JPH0753596A - インタフェロン - Google Patents

インタフェロン

Info

Publication number
JPH0753596A
JPH0753596A JP6057871A JP5787194A JPH0753596A JP H0753596 A JPH0753596 A JP H0753596A JP 6057871 A JP6057871 A JP 6057871A JP 5787194 A JP5787194 A JP 5787194A JP H0753596 A JPH0753596 A JP H0753596A
Authority
JP
Japan
Prior art keywords
plasmid
dna
interferon
fragment
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6057871A
Other languages
English (en)
Japanese (ja)
Inventor
Adolf Himmler
ヒムラー,アドルフ
Rudolf Hauptmann
ハウプトマン,ルドルフ
Norbert Hauel
ハウエル,ノルベルト
Gunther Adolf
アドルフ,ギユンター
Peter Swetly
スウエツトリイ,ピーター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of JPH0753596A publication Critical patent/JPH0753596A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP6057871A 1984-12-18 1994-03-28 インタフェロン Pending JPH0753596A (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE3446122 1984-12-18
DE3446124 1984-12-18
DE3529262 1985-08-16
DE35351152 1985-10-02
DE35292628 1985-10-02
DE34461248 1985-10-02
DE3535115 1985-10-02
DE34461221 1985-10-02

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP61500354A Division JPS62501469A (ja) 1984-12-18 1985-12-17 イヌおよびウマインタ−フエロン

Publications (1)

Publication Number Publication Date
JPH0753596A true JPH0753596A (ja) 1995-02-28

Family

ID=27433247

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6057871A Pending JPH0753596A (ja) 1984-12-18 1994-03-28 インタフェロン

Country Status (19)

Country Link
US (2) US5605688A (enExample)
EP (1) EP0186098B1 (enExample)
JP (1) JPH0753596A (enExample)
KR (1) KR940010864B1 (enExample)
AT (1) ATE77410T1 (enExample)
AU (1) AU604634B2 (enExample)
CA (1) CA1339954C (enExample)
DE (1) DE3544520C2 (enExample)
DK (1) DK167929B1 (enExample)
ES (1) ES8704515A1 (enExample)
FI (1) FI90990C (enExample)
GR (1) GR853062B (enExample)
HU (1) HU212836B (enExample)
IE (1) IE58685B1 (enExample)
IL (1) IL77369A (enExample)
NO (1) NO176057C (enExample)
NZ (1) NZ214602A (enExample)
PT (1) PT81691B (enExample)
WO (1) WO1986003775A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023535583A (ja) * 2020-07-31 2023-08-18 アイエルシー セラピューティクス リミテッド 疾病の治療に関する組成物および方法

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
US20020127200A1 (en) 1998-05-29 2002-09-12 Shumin Yang Canine and feline immunoregulatory proteins, nucleic acid molecules, and uses thereof
USRE40374E1 (en) 1998-05-29 2008-06-10 Heska Corporation Canine IL-13 immunoregulatory proteins and uses thereof
AU4102099A (en) 1998-05-29 1999-12-13 Heska Corporation Canine Interleukin -4 Proteins, Nucleic Acid Molecules, and Uses Thereof
US6482403B1 (en) 1998-05-29 2002-11-19 Heska Corporation Caniney IL-13 immunoregulatory proteins and uses thereof
CN101062419B (zh) 1998-10-16 2016-06-29 生物基因Ma公司 干扰素-β-1a的聚合物缀合物及其使用
CN100420482C (zh) * 2000-11-03 2008-09-24 精达制药公司 ω干扰素在制备用于治疗丙型肝炎的药物中的用途
CA2466228A1 (en) * 2001-11-09 2003-08-07 Biomedicines, Inc. Method for treating diseases with omega interferon
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
ATE481963T1 (de) 2006-05-30 2010-10-15 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
JP5351884B2 (ja) 2007-04-23 2013-11-27 インターシア セラピューティクス,インコーポレイティド インスリン分泌促進性ペプチドの懸濁製剤及び使用
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
HRP20180621T1 (hr) 2011-03-15 2018-07-27 Biogen Ma Inc. Postupak smanjivanja simptoma sličnih gripi, povezan s intramuskularnom primjenom interferona uz upotrebu režima rastuće doze uz brzo titranje
CN102321169A (zh) * 2011-09-30 2012-01-18 长春工业大学 一种犬重组干扰素α及制备方法
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
AU2016270984B2 (en) 2015-06-03 2021-02-25 Intarcia Therapeutics, Inc. Implant placement and removal systems
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
IL267736B2 (en) 2017-01-03 2024-03-01 Intarcia Therapeutics Inc Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
CN108424915A (zh) * 2018-01-12 2018-08-21 中国农业科学院北京畜牧兽医研究所 犬干扰素-α2重组蛋白的制备方法
CN108486127A (zh) * 2018-01-12 2018-09-04 中国农业科学院北京畜牧兽医研究所 犬干扰素-α6α7重组蛋白及其制备方法与应用
CN111233998B (zh) * 2018-08-02 2021-10-19 中国农业科学院北京畜牧兽医研究所 一种犬干扰素CaIFN-λ突变体及其应用
CN112079912B (zh) * 2020-09-25 2022-05-06 广州源博医药科技有限公司 一种高活性的犬α干扰素重组蛋白及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088622A2 (en) * 1982-03-08 1983-09-14 Genentech, Inc. Animal interferons, processes involved in their production, compositions containing them, DNA sequences coding therefor and expression vehicles containing such sequences and cells transformed thereby

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980002375A1 (en) * 1977-09-23 1980-11-13 Hem Res Inc High purity animal interferons
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells
AR241654A1 (es) * 1982-05-05 1992-10-30 Genentech Inc Procedimiento para producir activador de plasminogeno de tejido humano.
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
US4689224A (en) * 1985-10-07 1987-08-25 Neogen Corporation Method for administering vaccines containing equine leukokines and compositions therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088622A2 (en) * 1982-03-08 1983-09-14 Genentech, Inc. Animal interferons, processes involved in their production, compositions containing them, DNA sequences coding therefor and expression vehicles containing such sequences and cells transformed thereby

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023535583A (ja) * 2020-07-31 2023-08-18 アイエルシー セラピューティクス リミテッド 疾病の治療に関する組成物および方法

Also Published As

Publication number Publication date
WO1986003775A1 (fr) 1986-07-03
NO176057C (no) 1995-01-25
NO176057B (no) 1994-10-17
EP0186098A1 (de) 1986-07-02
DK167929B1 (da) 1994-01-03
ES550043A0 (es) 1987-04-01
FI854994L (fi) 1986-06-19
FI90990B (fi) 1994-01-14
ES8704515A1 (es) 1987-04-01
ATE77410T1 (de) 1992-07-15
AU5132085A (en) 1986-06-26
NZ214602A (en) 1991-06-25
NO855078L (no) 1986-06-19
AU604634B2 (en) 1991-01-03
PT81691A (de) 1986-01-01
GR853062B (enExample) 1986-04-21
US5605688A (en) 1997-02-25
DK586585A (da) 1986-06-19
FI854994A0 (fi) 1985-12-16
DE3544520C2 (de) 1995-07-20
DE3544520A1 (de) 1986-12-18
FI90990C (fi) 1994-04-25
KR940010864B1 (ko) 1994-11-18
KR860005020A (ko) 1986-07-16
IE58685B1 (en) 1994-02-09
CA1339954C (en) 1998-07-14
IL77369A (en) 1993-07-08
HU212836B (en) 1996-12-30
HUT40165A (en) 1986-11-28
EP0186098B1 (de) 1992-06-17
DK586585D0 (da) 1985-12-17
US5798228A (en) 1998-08-25
PT81691B (pt) 1988-04-21
IE853194L (en) 1986-06-18

Similar Documents

Publication Publication Date Title
JPH0753596A (ja) インタフェロン
JP2515308B2 (ja) ヒト免疫インタ−フエロン
JP2566909B2 (ja) 新規遺伝子配列、それによつてコ−ドされるi型インタ−フエロンペプチドおよびそのインタ−フエロンを産生する微生物
DK170054B1 (da) DNA-sekvenser, transformerede værtsorganismer, polypeptid med biologisk aktivitet som gamma-hesteinteferon, fremgangsmåde til fremstilling heraf og farmaceutisk præparat indeholdende polypeptidet
PL149079B1 (en) Method of obtaining polypeptides of ifn-beta type
JP2653061B2 (ja) 新規ポリペプチドおよびその製造法
JPS61129200A (ja) 新規な白血球インタ−フエロン
CN108840945A (zh) 猪白蛋白-干扰素α-白介素2融合蛋白、制备方法及其编码基因、一种猪长效干扰素
AU633278B2 (en) Isolation and cloning of complementary dna for gene coding of bovine trophoblast protein-1
WO2002081519A9 (fr) Nouvelle proteine hybride ifn-thy, preparation et utilisation
JPS62501469A (ja) イヌおよびウマインタ−フエロン
JPS62223199A (ja) 新規なペプチド
HRP950157A2 (en) Polypeptide with human interferon (ifn-gamma) characteristics