DE3544520C2 - Hunde-Interferone - Google Patents

Hunde-Interferone

Info

Publication number
DE3544520C2
DE3544520C2 DE3544520A DE3544520A DE3544520C2 DE 3544520 C2 DE3544520 C2 DE 3544520C2 DE 3544520 A DE3544520 A DE 3544520A DE 3544520 A DE3544520 A DE 3544520A DE 3544520 C2 DE3544520 C2 DE 3544520C2
Authority
DE
Germany
Prior art keywords
dna
plasmid
alpha
interferon
interferons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3544520A
Other languages
German (de)
English (en)
Other versions
DE3544520A1 (de
Inventor
Adolf Prof Dr Himmler
Rudolf Dr Hauptmann
Norbert Dr Hauel
Guenther Dr Adolf
Peter Dr Swetly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to DE3544520A priority Critical patent/DE3544520C2/de
Publication of DE3544520A1 publication Critical patent/DE3544520A1/de
Priority to US08/302,391 priority patent/US5605688A/en
Application granted granted Critical
Publication of DE3544520C2 publication Critical patent/DE3544520C2/de
Priority to US08/805,165 priority patent/US5798228A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DE3544520A 1984-12-18 1985-12-17 Hunde-Interferone Expired - Fee Related DE3544520C2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE3544520A DE3544520C2 (de) 1984-12-18 1985-12-17 Hunde-Interferone
US08/302,391 US5605688A (en) 1984-12-18 1994-09-08 Recombinant dog and horse type I interferons
US08/805,165 US5798228A (en) 1984-12-18 1997-02-24 Recombinant production of dog and horse type I interferons

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE3446122 1984-12-18
DE3446124 1984-12-18
DE3529262 1985-08-16
DE3535115 1985-10-02
DE3544520A DE3544520C2 (de) 1984-12-18 1985-12-17 Hunde-Interferone

Publications (2)

Publication Number Publication Date
DE3544520A1 DE3544520A1 (de) 1986-12-18
DE3544520C2 true DE3544520C2 (de) 1995-07-20

Family

ID=27433247

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3544520A Expired - Fee Related DE3544520C2 (de) 1984-12-18 1985-12-17 Hunde-Interferone

Country Status (19)

Country Link
US (2) US5605688A (enExample)
EP (1) EP0186098B1 (enExample)
JP (1) JPH0753596A (enExample)
KR (1) KR940010864B1 (enExample)
AT (1) ATE77410T1 (enExample)
AU (1) AU604634B2 (enExample)
CA (1) CA1339954C (enExample)
DE (1) DE3544520C2 (enExample)
DK (1) DK167929B1 (enExample)
ES (1) ES8704515A1 (enExample)
FI (1) FI90990C (enExample)
GR (1) GR853062B (enExample)
HU (1) HU212836B (enExample)
IE (1) IE58685B1 (enExample)
IL (1) IL77369A (enExample)
NO (1) NO176057C (enExample)
NZ (1) NZ214602A (enExample)
PT (1) PT81691B (enExample)
WO (1) WO1986003775A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
US20020127200A1 (en) 1998-05-29 2002-09-12 Shumin Yang Canine and feline immunoregulatory proteins, nucleic acid molecules, and uses thereof
USRE40374E1 (en) 1998-05-29 2008-06-10 Heska Corporation Canine IL-13 immunoregulatory proteins and uses thereof
AU4102099A (en) 1998-05-29 1999-12-13 Heska Corporation Canine Interleukin -4 Proteins, Nucleic Acid Molecules, and Uses Thereof
US6482403B1 (en) 1998-05-29 2002-11-19 Heska Corporation Caniney IL-13 immunoregulatory proteins and uses thereof
CN101062419B (zh) 1998-10-16 2016-06-29 生物基因Ma公司 干扰素-β-1a的聚合物缀合物及其使用
CN100420482C (zh) * 2000-11-03 2008-09-24 精达制药公司 ω干扰素在制备用于治疗丙型肝炎的药物中的用途
CA2466228A1 (en) * 2001-11-09 2003-08-07 Biomedicines, Inc. Method for treating diseases with omega interferon
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
ATE481963T1 (de) 2006-05-30 2010-10-15 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
JP5351884B2 (ja) 2007-04-23 2013-11-27 インターシア セラピューティクス，インコーポレイティド インスリン分泌促進性ペプチドの懸濁製剤及び使用
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
HRP20180621T1 (hr) 2011-03-15 2018-07-27 Biogen Ma Inc. Postupak smanjivanja simptoma sličnih gripi, povezan s intramuskularnom primjenom interferona uz upotrebu režima rastuće doze uz brzo titranje
CN102321169A (zh) * 2011-09-30 2012-01-18 长春工业大学 一种犬重组干扰素α及制备方法
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
AU2016270984B2 (en) 2015-06-03 2021-02-25 Intarcia Therapeutics, Inc. Implant placement and removal systems
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
IL267736B2 (en) 2017-01-03 2024-03-01 Intarcia Therapeutics Inc Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
CN108424915A (zh) * 2018-01-12 2018-08-21 中国农业科学院北京畜牧兽医研究所 犬干扰素-α2重组蛋白的制备方法
CN108486127A (zh) * 2018-01-12 2018-09-04 中国农业科学院北京畜牧兽医研究所 犬干扰素-α6α7重组蛋白及其制备方法与应用
CN111233998B (zh) * 2018-08-02 2021-10-19 中国农业科学院北京畜牧兽医研究所 一种犬干扰素CaIFN-λ突变体及其应用
GB202011945D0 (en) * 2020-07-31 2020-09-16 Ilc Therapeutics Ltd Compositions and methods relating to the treatment of diseases
CN112079912B (zh) * 2020-09-25 2022-05-06 广州源博医药科技有限公司 一种高活性的犬α干扰素重组蛋白及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980002375A1 (en) * 1977-09-23 1980-11-13 Hem Res Inc High purity animal interferons
US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
AR241654A1 (es) * 1982-05-05 1992-10-30 Genentech Inc Procedimiento para producir activador de plasminogeno de tejido humano.
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
US4689224A (en) * 1985-10-07 1987-08-25 Neogen Corporation Method for administering vaccines containing equine leukokines and compositions therefor

Also Published As

Publication number Publication date
WO1986003775A1 (fr) 1986-07-03
NO176057C (no) 1995-01-25
NO176057B (no) 1994-10-17
EP0186098A1 (de) 1986-07-02
DK167929B1 (da) 1994-01-03
ES550043A0 (es) 1987-04-01
FI854994L (fi) 1986-06-19
FI90990B (fi) 1994-01-14
ES8704515A1 (es) 1987-04-01
ATE77410T1 (de) 1992-07-15
AU5132085A (en) 1986-06-26
NZ214602A (en) 1991-06-25
NO855078L (no) 1986-06-19
AU604634B2 (en) 1991-01-03
PT81691A (de) 1986-01-01
GR853062B (enExample) 1986-04-21
JPH0753596A (ja) 1995-02-28
US5605688A (en) 1997-02-25
DK586585A (da) 1986-06-19
FI854994A0 (fi) 1985-12-16
DE3544520A1 (de) 1986-12-18
FI90990C (fi) 1994-04-25
KR940010864B1 (ko) 1994-11-18
KR860005020A (ko) 1986-07-16
IE58685B1 (en) 1994-02-09
CA1339954C (en) 1998-07-14
IL77369A (en) 1993-07-08
HU212836B (en) 1996-12-30
HUT40165A (en) 1986-11-28
EP0186098B1 (de) 1992-06-17
DK586585D0 (da) 1985-12-17
US5798228A (en) 1998-08-25
PT81691B (pt) 1988-04-21
IE853194L (en) 1986-06-18

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee