DK167929B1 - Rekombinant dna-molekyle indeholdende en for hesteinterferoner kodende sekvens, transformeret vaertsorganisme indeholdende dna-molekylet, interferon kodet af det rekombinante dna-molekyle, fremgangsmaade til fremstilling af heste-interferoner, anvendelse af interferonerne, middel til terapeutisk behandling samt heste-interferon til anvendelse som laegemiddel - Google Patents

Rekombinant dna-molekyle indeholdende en for hesteinterferoner kodende sekvens, transformeret vaertsorganisme indeholdende dna-molekylet, interferon kodet af det rekombinante dna-molekyle, fremgangsmaade til fremstilling af heste-interferoner, anvendelse af interferonerne, middel til terapeutisk behandling samt heste-interferon til anvendelse som laegemiddel Download PDF

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Publication number
DK167929B1
DK167929B1 DK586585A DK586585A DK167929B1 DK 167929 B1 DK167929 B1 DK 167929B1 DK 586585 A DK586585 A DK 586585A DK 586585 A DK586585 A DK 586585A DK 167929 B1 DK167929 B1 DK 167929B1
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ctg
gag
glu
gin
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DK586585A
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Danish (da)
English (en)
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DK586585A (da
DK586585D0 (da
Inventor
A Himmler
R Hauptmann
N Hauel
G Adolf
P Swetly
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Boehringer Ingelheim Int
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DK586585A 1984-12-18 1985-12-17 Rekombinant dna-molekyle indeholdende en for hesteinterferoner kodende sekvens, transformeret vaertsorganisme indeholdende dna-molekylet, interferon kodet af det rekombinante dna-molekyle, fremgangsmaade til fremstilling af heste-interferoner, anvendelse af interferonerne, middel til terapeutisk behandling samt heste-interferon til anvendelse som laegemiddel DK167929B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE3446124 1984-12-18
DE3446122 1984-12-18
DE3446122 1984-12-18
DE3446124 1984-12-18
DE3529262 1985-08-16
DE3529262 1985-08-16
DE3535115 1985-10-02
DE3535115 1985-10-02

Publications (3)

Publication Number Publication Date
DK586585D0 DK586585D0 (da) 1985-12-17
DK586585A DK586585A (da) 1986-06-19
DK167929B1 true DK167929B1 (da) 1994-01-03

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK586585A DK167929B1 (da) 1984-12-18 1985-12-17 Rekombinant dna-molekyle indeholdende en for hesteinterferoner kodende sekvens, transformeret vaertsorganisme indeholdende dna-molekylet, interferon kodet af det rekombinante dna-molekyle, fremgangsmaade til fremstilling af heste-interferoner, anvendelse af interferonerne, middel til terapeutisk behandling samt heste-interferon til anvendelse som laegemiddel

Country Status (19)

Country Link
US (2) US5605688A (enExample)
EP (1) EP0186098B1 (enExample)
JP (1) JPH0753596A (enExample)
KR (1) KR940010864B1 (enExample)
AT (1) ATE77410T1 (enExample)
AU (1) AU604634B2 (enExample)
CA (1) CA1339954C (enExample)
DE (1) DE3544520C2 (enExample)
DK (1) DK167929B1 (enExample)
ES (1) ES8704515A1 (enExample)
FI (1) FI90990C (enExample)
GR (1) GR853062B (enExample)
HU (1) HU212836B (enExample)
IE (1) IE58685B1 (enExample)
IL (1) IL77369A (enExample)
NO (1) NO176057C (enExample)
NZ (1) NZ214602A (enExample)
PT (1) PT81691B (enExample)
WO (1) WO1986003775A1 (enExample)

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DE3642096A1 (de) * 1986-12-10 1988-06-16 Boehringer Ingelheim Int Pferde-(gamma)-interferon
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
US20020127200A1 (en) 1998-05-29 2002-09-12 Shumin Yang Canine and feline immunoregulatory proteins, nucleic acid molecules, and uses thereof
USRE40374E1 (en) 1998-05-29 2008-06-10 Heska Corporation Canine IL-13 immunoregulatory proteins and uses thereof
AU4102099A (en) 1998-05-29 1999-12-13 Heska Corporation Canine Interleukin -4 Proteins, Nucleic Acid Molecules, and Uses Thereof
US6482403B1 (en) 1998-05-29 2002-11-19 Heska Corporation Caniney IL-13 immunoregulatory proteins and uses thereof
CN101062419B (zh) 1998-10-16 2016-06-29 生物基因Ma公司 干扰素-β-1a的聚合物缀合物及其使用
CN100420482C (zh) * 2000-11-03 2008-09-24 精达制药公司 ω干扰素在制备用于治疗丙型肝炎的药物中的用途
CA2466228A1 (en) * 2001-11-09 2003-08-07 Biomedicines, Inc. Method for treating diseases with omega interferon
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
ATE481963T1 (de) 2006-05-30 2010-10-15 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
PL2359808T3 (pl) 2006-08-09 2013-10-31 Intarcia Therapeutics Inc Osmotyczne systemy dostawcze i zespoły tłokowe
JP5351884B2 (ja) 2007-04-23 2013-11-27 インターシア セラピューティクス,インコーポレイティド インスリン分泌促進性ペプチドの懸濁製剤及び使用
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
RU2547990C2 (ru) 2009-09-28 2015-04-10 Интарсия Терапьютикс, Инк. Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
HRP20180621T1 (hr) 2011-03-15 2018-07-27 Biogen Ma Inc. Postupak smanjivanja simptoma sličnih gripi, povezan s intramuskularnom primjenom interferona uz upotrebu režima rastuće doze uz brzo titranje
CN102321169A (zh) * 2011-09-30 2012-01-18 长春工业大学 一种犬重组干扰素α及制备方法
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
AU2016270984B2 (en) 2015-06-03 2021-02-25 Intarcia Therapeutics, Inc. Implant placement and removal systems
SG11201810102SA (en) 2016-05-16 2018-12-28 Intarcia Therapeutics Inc Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
IL267736B2 (en) 2017-01-03 2024-03-01 Intarcia Therapeutics Inc Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
CN108424915A (zh) * 2018-01-12 2018-08-21 中国农业科学院北京畜牧兽医研究所 犬干扰素-α2重组蛋白的制备方法
CN108486127A (zh) * 2018-01-12 2018-09-04 中国农业科学院北京畜牧兽医研究所 犬干扰素-α6α7重组蛋白及其制备方法与应用
CN111233998B (zh) * 2018-08-02 2021-10-19 中国农业科学院北京畜牧兽医研究所 一种犬干扰素CaIFN-λ突变体及其应用
GB202011945D0 (en) * 2020-07-31 2020-09-16 Ilc Therapeutics Ltd Compositions and methods relating to the treatment of diseases
CN112079912B (zh) * 2020-09-25 2022-05-06 广州源博医药科技有限公司 一种高活性的犬α干扰素重组蛋白及其制备方法和应用

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US4262090A (en) * 1979-06-04 1981-04-14 Cetus Corporation Interferon production
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
ATE25985T1 (de) * 1980-06-12 1987-04-15 Japan Found Cancer Plasmid.
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
AR241654A1 (es) * 1982-05-05 1992-10-30 Genentech Inc Procedimiento para producir activador de plasminogeno de tejido humano.
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
JPS60118196A (ja) * 1983-11-30 1985-06-25 Takeda Chem Ind Ltd インタ−フェロンの製造法
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
FI90990C (fi) * 1984-12-18 1994-04-25 Boehringer Ingelheim Int Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
US4689224A (en) * 1985-10-07 1987-08-25 Neogen Corporation Method for administering vaccines containing equine leukokines and compositions therefor

Also Published As

Publication number Publication date
WO1986003775A1 (fr) 1986-07-03
NO176057C (no) 1995-01-25
NO176057B (no) 1994-10-17
EP0186098A1 (de) 1986-07-02
ES550043A0 (es) 1987-04-01
FI854994L (fi) 1986-06-19
FI90990B (fi) 1994-01-14
ES8704515A1 (es) 1987-04-01
ATE77410T1 (de) 1992-07-15
AU5132085A (en) 1986-06-26
NZ214602A (en) 1991-06-25
NO855078L (no) 1986-06-19
AU604634B2 (en) 1991-01-03
PT81691A (de) 1986-01-01
GR853062B (enExample) 1986-04-21
JPH0753596A (ja) 1995-02-28
US5605688A (en) 1997-02-25
DK586585A (da) 1986-06-19
FI854994A0 (fi) 1985-12-16
DE3544520C2 (de) 1995-07-20
DE3544520A1 (de) 1986-12-18
FI90990C (fi) 1994-04-25
KR940010864B1 (ko) 1994-11-18
KR860005020A (ko) 1986-07-16
IE58685B1 (en) 1994-02-09
CA1339954C (en) 1998-07-14
IL77369A (en) 1993-07-08
HU212836B (en) 1996-12-30
HUT40165A (en) 1986-11-28
EP0186098B1 (de) 1992-06-17
DK586585D0 (da) 1985-12-17
US5798228A (en) 1998-08-25
PT81691B (pt) 1988-04-21
IE853194L (en) 1986-06-18

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed