KR930007880A - 비스(페닐)에탄 유도체 - Google Patents
비스(페닐)에탄 유도체 Download PDFInfo
- Publication number
- KR930007880A KR930007880A KR1019920018971A KR920018971A KR930007880A KR 930007880 A KR930007880 A KR 930007880A KR 1019920018971 A KR1019920018971 A KR 1019920018971A KR 920018971 A KR920018971 A KR 920018971A KR 930007880 A KR930007880 A KR 930007880A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- alkoxy
- formula
- acyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- BSZXAFXFTLXUFV-UHFFFAOYSA-N 1-phenylethylbenzene Chemical class C=1C=CC=CC=1C(C)C1=CC=CC=C1 BSZXAFXFTLXUFV-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 claims abstract 9
- 150000001875 compounds Chemical class 0.000 claims abstract 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 4
- 125000002252 acyl group Chemical group 0.000 claims abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 4
- 239000001257 hydrogen Substances 0.000 claims abstract 4
- 150000003839 salts Chemical group 0.000 claims abstract 4
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 claims 1
- 125000005677 ethinylene group Chemical group [*:2]C#C[*:1] 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- GZOFTOHENYHNMS-UHFFFAOYSA-N methyl 5-[2-(2,5-dimethoxyphenyl)ethyl]-2-hydroxybenzoate Chemical compound C1=C(O)C(C(=O)OC)=CC(CCC=2C(=CC=C(OC)C=2)OC)=C1 GZOFTOHENYHNMS-UHFFFAOYSA-N 0.000 claims 1
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 238000005809 transesterification reaction Methods 0.000 claims 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- External Artificial Organs (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Photoreceptors In Electrophotography (AREA)
- Paints Or Removers (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9121943 | 1991-10-16 | ||
| GB919121943A GB9121943D0 (en) | 1991-10-16 | 1991-10-16 | Organic compounds,processes for their production and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR930007880A true KR930007880A (ko) | 1993-05-20 |
Family
ID=10703010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920018971A Ceased KR930007880A (ko) | 1991-10-16 | 1992-10-15 | 비스(페닐)에탄 유도체 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5488135A (https=) |
| EP (1) | EP0539326B1 (https=) |
| JP (1) | JP2543298B2 (https=) |
| KR (1) | KR930007880A (https=) |
| AT (1) | ATE136536T1 (https=) |
| AU (1) | AU653441B2 (https=) |
| CA (1) | CA2080555C (https=) |
| CZ (1) | CZ282473B6 (https=) |
| DE (1) | DE69209771T2 (https=) |
| DK (1) | DK0539326T3 (https=) |
| ES (1) | ES2087499T3 (https=) |
| FI (1) | FI924657A7 (https=) |
| GB (1) | GB9121943D0 (https=) |
| GR (1) | GR3019856T3 (https=) |
| HK (1) | HK146696A (https=) |
| HU (2) | HU215151B (https=) |
| IL (1) | IL103417A (https=) |
| MX (1) | MX9205921A (https=) |
| NO (1) | NO178540C (https=) |
| NZ (1) | NZ244730A (https=) |
| PH (1) | PH31113A (https=) |
| RO (1) | RO111074B1 (https=) |
| RU (1) | RU2118311C1 (https=) |
| SG (1) | SG50542A1 (https=) |
| SK (1) | SK312592A3 (https=) |
| TW (1) | TW221051B (https=) |
| ZA (1) | ZA928021B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69616993T2 (de) * | 1995-03-14 | 2002-07-04 | Novartis Ag, Basel | Trisubstituierte phenyl derivate |
| DE10015525A1 (de) * | 2000-03-30 | 2001-10-11 | Deutsches Krebsforsch | Synthetische Derivate von Lunularsäure, Arzneimittel enthaltend diese Verbindung, Verfahren zur Herstellung der Lunularsäurederivate sowie deren Verwendung |
| US7103979B2 (en) | 2001-04-20 | 2006-09-12 | Hitachi Koki Co., Ltd. | Portable electric cutting device with blower mechanism |
| ES2204300B1 (es) * | 2002-07-18 | 2005-05-01 | J. URIACH & CIA S.A. | Nuevos derivados del acido 2,4-dihidroxibenzoico. |
| DE10349088A1 (de) | 2002-10-22 | 2004-09-09 | Hitachi Koki Co., Ltd. | Elektrische Handschneidvorrichtung mit Gebläsemechanismus |
| JP3765425B2 (ja) | 2004-01-26 | 2006-04-12 | 日立工機株式会社 | 携帯用電動切断機 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE269619C (https=) * | ||||
| DE293108C (https=) * | ||||
| US3657430A (en) * | 1969-06-25 | 1972-04-18 | Merck & Co Inc | Composition and methods for treating inflammation |
| EP0028305B1 (en) * | 1979-09-13 | 1984-02-01 | The Wellcome Foundation Limited | Diaryl compounds and pharmaceutical formulations containing them |
| WO1988003806A1 (en) * | 1986-11-19 | 1988-06-02 | Chemex Pharmaceuticals, Inc. | Pharmacologically active compositions of catecholic butanes with zinc |
| WO1988003800A1 (en) * | 1986-11-19 | 1988-06-02 | Chemex Pharmaceuticals, Inc. | Lipoxygenase inhibitors |
| HUT60458A (en) * | 1991-02-01 | 1992-09-28 | Sandoz Ag | Process for producing benzyloxyphenyl derivatives and pharmaceutical compositions comprising same |
| US5409930A (en) * | 1991-05-10 | 1995-04-25 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
-
1991
- 1991-10-16 GB GB919121943A patent/GB9121943D0/en active Pending
-
1992
- 1992-10-05 HU HU9203156A patent/HU215151B/hu not_active IP Right Cessation
- 1992-10-13 EP EP92810782A patent/EP0539326B1/en not_active Expired - Lifetime
- 1992-10-13 AT AT92810782T patent/ATE136536T1/de not_active IP Right Cessation
- 1992-10-13 DK DK92810782.0T patent/DK0539326T3/da active
- 1992-10-13 ES ES92810782T patent/ES2087499T3/es not_active Expired - Lifetime
- 1992-10-13 DE DE69209771T patent/DE69209771T2/de not_active Expired - Lifetime
- 1992-10-13 SG SG1996004564A patent/SG50542A1/en unknown
- 1992-10-14 CA CA002080555A patent/CA2080555C/en not_active Expired - Fee Related
- 1992-10-14 NO NO923983A patent/NO178540C/no unknown
- 1992-10-14 NZ NZ244730A patent/NZ244730A/en unknown
- 1992-10-14 RO RO92-01311A patent/RO111074B1/ro unknown
- 1992-10-14 IL IL10341792A patent/IL103417A/xx not_active IP Right Cessation
- 1992-10-14 CZ CS923125A patent/CZ282473B6/cs not_active IP Right Cessation
- 1992-10-14 FI FI924657A patent/FI924657A7/fi unknown
- 1992-10-14 AU AU27044/92A patent/AU653441B2/en not_active Ceased
- 1992-10-14 SK SK3125-92A patent/SK312592A3/sk unknown
- 1992-10-15 JP JP4277054A patent/JP2543298B2/ja not_active Expired - Fee Related
- 1992-10-15 MX MX9205921A patent/MX9205921A/es not_active IP Right Cessation
- 1992-10-15 KR KR1019920018971A patent/KR930007880A/ko not_active Ceased
- 1992-10-15 RU RU92004377A patent/RU2118311C1/ru active
- 1992-10-16 PH PH45119A patent/PH31113A/en unknown
- 1992-10-16 ZA ZA928021A patent/ZA928021B/xx unknown
- 1992-10-16 US US07/962,370 patent/US5488135A/en not_active Expired - Lifetime
- 1992-10-17 TW TW081108265A patent/TW221051B/zh active
-
1995
- 1995-06-19 HU HU95P/P00247P patent/HU211233A9/hu unknown
-
1996
- 1996-05-07 GR GR960401241T patent/GR3019856T3/el unknown
- 1996-08-01 HK HK146696A patent/HK146696A/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR850000406A (ko) | 4-클로로-2-페닐이미다졸-5-아세트산유도체의 제조방법 | |
| KR960004352A (ko) | 유기금속 유도체와 그것의 제법과정 | |
| EP1437359A3 (en) | Novel 3,6-Hemiketals from the Class of 9a-Azalides | |
| KR950011462A (ko) | 호르몬 활성이 저하된 에스트라디올 유도체-알킬화제 결합체, 그의 제조방법, 그의 제조에 유용한 화합물, 및 상기 결합체 또는 에스트라디올 유도체를 함유하는 성장억제조성물 | |
| KR900018048A (ko) | 환 치환된 2-아미노-1,2,3,4-테트라하이드로나프탈렌 | |
| KR890014486A (ko) | N-시클로프로필아닐, 및 1-시클로프로필-퀴놀론카르복실산 및 그의 유도체의 제조에 있어서 n-시클로프로필아닐린의 용도 | |
| KR930007880A (ko) | 비스(페닐)에탄 유도체 | |
| KR910016727A (ko) | 1,5-벤조티아제핀 유도체의 제조방법 | |
| KR830007683A (ko) | 7β-[2-(2-아미노-4-티아졸릴)-2-(신)-메톡시 아미노 아세트 아미도]-3-세펨-4-카복실산의 에스테르의 제조방법 | |
| KR880009926A (ko) | 알킬멜라토닌 | |
| KR840004757A (ko) | 세파로스포린 유도체의 제조방법 | |
| KR950010897A (ko) | 신규의 화학적 보호제(chemopreventive agent) 및 그의 제조방법 | |
| KR850006176A (ko) | (아릴티오) 피리딜 알칼올 유도체의 제조방법 | |
| KR900003179A (ko) | 벤조디아제핀 화합물 및 약제로서의 이의 용도 | |
| KR850001766A (ko) | 무라밀디펩타이드 활성 에스테르 유도체의 제조방법 | |
| KR890008121A (ko) | 로다닌 유도체 및 약제학적 조성물 | |
| KR900000378A (ko) | 타이로신유도체 및 그 제조법 | |
| KR830001900A (ko) | 페닐모르판과 그의 중간물질및 제조방법 | |
| KR920002594A (ko) | 5-이소티아졸아민 유도체 | |
| KR920700210A (ko) | 신규 이미다졸 유도체, 그의 제법 및 그의 의약용도 | |
| KR920002564A (ko) | N-알킬 티아졸리딘 유도체 | |
| KR960000882A (ko) | 신규한 피리돈 카르본산 유도체 및 그의 제조방법 | |
| KR940003950A (ko) | 다가 페놀 화합물의 제조방법 | |
| KR920009818A (ko) | 신규 벤조디옥솔 유도체 및 이를 함유하는 간장해 개선제 | |
| KR860008999A (ko) | N- 페닐-4-페닐-1- 피페라진카복스아미딘의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19921015 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19971014 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19921015 Comment text: Patent Application |
|
| N231 | Notification of change of applicant | ||
| PN2301 | Change of applicant |
Patent event date: 19980227 Comment text: Notification of Change of Applicant Patent event code: PN23011R01D |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19990731 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 19991029 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19990731 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |