KR920701242A - 환원된 비가역성 봄베신 길항제 - Google Patents

환원된 비가역성 봄베신 길항제

Info

Publication number
KR920701242A
KR920701242A KR1019910700701A KR910700701A KR920701242A KR 920701242 A KR920701242 A KR 920701242A KR 1019910700701 A KR1019910700701 A KR 1019910700701A KR 910700701 A KR910700701 A KR 910700701A KR 920701242 A KR920701242 A KR 920701242A
Authority
KR
South Korea
Prior art keywords
residue
peptide
clch
group
leu
Prior art date
Application number
KR1019910700701A
Other languages
English (en)
Korean (ko)
Inventor
드 카스티글리오네 로베르토
고지니 루이지아
코라디 파비오
치오메이 마리나
몰리나리 이사벨라
프란제티 크리스티나
Original Assignee
원본미기재
팜이탈리아 카를로 에르바 에스.알.엘
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898925024A external-priority patent/GB8925024D0/en
Priority claimed from GB909006413A external-priority patent/GB9006413D0/en
Application filed by 원본미기재, 팜이탈리아 카를로 에르바 에스.알.엘 filed Critical 원본미기재
Publication of KR920701242A publication Critical patent/KR920701242A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
KR1019910700701A 1989-11-06 1990-11-02 환원된 비가역성 봄베신 길항제 KR920701242A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB898925024A GB8925024D0 (en) 1989-11-06 1989-11-06 Reduced irreversible bombesin antagonists
GB89250245 1989-11-06
GB909006413A GB9006413D0 (en) 1990-03-22 1990-03-22 Reduced irreversible bombesin antagonists
GB90064130 1990-03-22
PCT/EP1990/001836 WO1991006563A1 (en) 1989-11-06 1990-11-02 Reduced irreversible bombesin antagonists

Publications (1)

Publication Number Publication Date
KR920701242A true KR920701242A (ko) 1992-08-11

Family

ID=26296160

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910700701A KR920701242A (ko) 1989-11-06 1990-11-02 환원된 비가역성 봄베신 길항제

Country Status (9)

Country Link
EP (1) EP0452447A1 (ja)
JP (1) JPH04502629A (ja)
KR (1) KR920701242A (ja)
AU (1) AU6610390A (ja)
CA (1) CA2045494A1 (ja)
HU (1) HUT58763A (ja)
IE (1) IE903958A1 (ja)
IL (1) IL96216A0 (ja)
WO (1) WO1991006563A1 (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834433A (en) * 1990-07-26 1998-11-10 Merrell Pharmaceuticals Inc. Compounds and pharmaceutical uses of peptides of bombesin and GRP
ES2106188T3 (es) * 1991-05-23 1997-11-01 Merrell Pharma Inc Analogos de bombesina.
WO1993016105A1 (en) * 1992-02-07 1993-08-19 Merrell Dow Pharmaceuticals Inc. Phenylalanine analogs of bombesin
WO2004093807A2 (en) 2003-04-22 2004-11-04 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin vectors
EP2848628A1 (en) * 2010-01-25 2015-03-18 Cornell University Aromatic-cationic peptides and uses of same
CA2886068C (en) 2012-09-25 2021-06-22 Advanced Accelerator Applications Usa, Inc. Radiolabeled grpr-antagonists for diagnostic imaging and treatment of grpr-positive cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
GB8808768D0 (en) * 1988-04-14 1988-05-18 Erba Carlo Spa Peptide ligands for bombesin receptors
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
MC2144A1 (fr) * 1988-10-14 1992-02-19 Univ Tulane Peptides therapeutiques

Also Published As

Publication number Publication date
WO1991006563A1 (en) 1991-05-16
CA2045494A1 (en) 1991-05-07
JPH04502629A (ja) 1992-05-14
AU6610390A (en) 1991-05-31
IE903958A1 (en) 1991-05-08
IL96216A0 (en) 1991-08-16
HUT58763A (en) 1992-03-30
EP0452447A1 (en) 1991-10-23
HU912604D0 (en) 1992-01-28

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Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid