CA2045494A1 - Reduced irreversible bombesin antagonists - Google Patents

Reduced irreversible bombesin antagonists

Info

Publication number
CA2045494A1
CA2045494A1 CA002045494A CA2045494A CA2045494A1 CA 2045494 A1 CA2045494 A1 CA 2045494A1 CA 002045494 A CA002045494 A CA 002045494A CA 2045494 A CA2045494 A CA 2045494A CA 2045494 A1 CA2045494 A1 CA 2045494A1
Authority
CA
Canada
Prior art keywords
leu
residue
gly
peptide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002045494A
Other languages
English (en)
French (fr)
Inventor
Luigia Gozzini
Fabio Corradi
Marina Ciomei
Isabella Molinari
Cristina Franzetti
Roberto De Castiglione
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898925024A external-priority patent/GB8925024D0/en
Priority claimed from GB909006413A external-priority patent/GB9006413D0/en
Application filed by Individual filed Critical Individual
Publication of CA2045494A1 publication Critical patent/CA2045494A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C07K7/086—Bombesin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Steroid Compounds (AREA)
CA002045494A 1989-11-06 1990-11-02 Reduced irreversible bombesin antagonists Abandoned CA2045494A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB898925024A GB8925024D0 (en) 1989-11-06 1989-11-06 Reduced irreversible bombesin antagonists
GB8925024.5 1989-11-06
GB9006413.0 1990-03-22
GB909006413A GB9006413D0 (en) 1990-03-22 1990-03-22 Reduced irreversible bombesin antagonists

Publications (1)

Publication Number Publication Date
CA2045494A1 true CA2045494A1 (en) 1991-05-07

Family

ID=26296160

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002045494A Abandoned CA2045494A1 (en) 1989-11-06 1990-11-02 Reduced irreversible bombesin antagonists

Country Status (9)

Country Link
EP (1) EP0452447A1 (ja)
JP (1) JPH04502629A (ja)
KR (1) KR920701242A (ja)
AU (1) AU6610390A (ja)
CA (1) CA2045494A1 (ja)
HU (1) HUT58763A (ja)
IE (1) IE903958A1 (ja)
IL (1) IL96216A0 (ja)
WO (1) WO1991006563A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9839703B2 (en) 2012-09-25 2017-12-12 Advanced Accelerator Applications Usa, Inc. Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834433A (en) * 1990-07-26 1998-11-10 Merrell Pharmaceuticals Inc. Compounds and pharmaceutical uses of peptides of bombesin and GRP
ES2106188T3 (es) * 1991-05-23 1997-11-01 Merrell Pharma Inc Analogos de bombesina.
WO1993016105A1 (en) * 1992-02-07 1993-08-19 Merrell Dow Pharmaceuticals Inc. Phenylalanine analogs of bombesin
WO2004093807A2 (en) 2003-04-22 2004-11-04 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin vectors
EP2848628A1 (en) * 2010-01-25 2015-03-18 Cornell University Aromatic-cationic peptides and uses of same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795449B2 (ja) * 1987-09-24 1998-09-10 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ペプチド
GB8808768D0 (en) * 1988-04-14 1988-05-18 Erba Carlo Spa Peptide ligands for bombesin receptors
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
MC2144A1 (fr) * 1988-10-14 1992-02-19 Univ Tulane Peptides therapeutiques

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9839703B2 (en) 2012-09-25 2017-12-12 Advanced Accelerator Applications Usa, Inc. Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer
US11083805B2 (en) 2012-09-25 2021-08-10 Advanced Accelerator Applications International Sa Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer
US12064489B2 (en) 2012-09-25 2024-08-20 Advanced Accelerator Applications International Sa Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer
US12064491B2 (en) 2012-09-25 2024-08-20 Advanced Accelerator Applications International Sa Radiolabeled GRPR-antagonists for diagnostic imaging and treatment of GRPR-positive cancer
US12064490B2 (en) 2012-09-25 2024-08-20 Advanced Accelerator Applications International Sa Radiolabeled GRPR-Antagonists for Diagnostic Imaging and Treatment of GRPR-Positive Cancer

Also Published As

Publication number Publication date
WO1991006563A1 (en) 1991-05-16
JPH04502629A (ja) 1992-05-14
AU6610390A (en) 1991-05-31
IE903958A1 (en) 1991-05-08
IL96216A0 (en) 1991-08-16
HUT58763A (en) 1992-03-30
EP0452447A1 (en) 1991-10-23
KR920701242A (ko) 1992-08-11
HU912604D0 (en) 1992-01-28

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Legal Events

Date Code Title Description
FZDE Discontinued