KR920701217A - 리피드 a 단당류 녹체 - Google Patents

리피드 a 단당류 녹체

Info

Publication number
KR920701217A
KR920701217A KR1019910700512A KR910700512A KR920701217A KR 920701217 A KR920701217 A KR 920701217A KR 1019910700512 A KR1019910700512 A KR 1019910700512A KR 910700512 A KR910700512 A KR 910700512A KR 920701217 A KR920701217 A KR 920701217A
Authority
KR
South Korea
Prior art keywords
monosaccharide
lipid
green body
integer
rust
Prior art date
Application number
KR1019910700512A
Other languages
English (en)
Other versions
KR940005344B1 (ko
Inventor
아끼라 하세가와
마고또 기소
신이찌 우에사또
마사노브 스즈끼
도미오 이시다
유다까 사이또
Original Assignee
아끼라 하세가와
미즈노 시게루
니흥 다바꼬 상교 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아끼라 하세가와, 미즈노 시게루, 니흥 다바꼬 상교 가부시끼가이샤 filed Critical 아끼라 하세가와
Publication of KR920701217A publication Critical patent/KR920701217A/ko
Application granted granted Critical
Publication of KR940005344B1 publication Critical patent/KR940005344B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Lubricants (AREA)

Abstract

내용 없음

Description

리피드 A 단당류 녹체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 일반식
    (식중, R1은 수소원자 또는 히드록실기를 의미하고, ℓ은 8-14의 정수를, m은 11-17의 정수를 n은 8-14의 정수를 의미한다)로 나타내는 것을 특징으로 하는 리피드 A 단당류녹체.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910700512A 1989-09-20 1990-09-20 리피드a 단당류 녹체 KR940005344B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1241866A JPH0655749B2 (ja) 1989-09-20 1989-09-20 リピッドａ単糖類縁体
JP1-241866 1989-09-20
PCT/JP1990/001208 WO1991004259A1 (fr) 1989-09-20 1990-09-20 Analogue de monosaccharide a lipidique

Publications (2)

Publication Number Publication Date
KR920701217A true KR920701217A (ko) 1992-08-11
KR940005344B1 KR940005344B1 (ko) 1994-06-17

Family

ID=17080690

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910700512A KR940005344B1 (ko) 1989-09-20 1990-09-20 리피드a 단당류 녹체

Country Status (6)

Country Link
US (1) US5191072A (ko)
EP (1) EP0444208A4 (ko)
JP (1) JPH0655749B2 (ko)
KR (1) KR940005344B1 (ko)
CA (1) CA2042053C (ko)
WO (1) WO1991004259A1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660325B2 (en) * 1991-10-11 1995-06-22 Eisai Co. Ltd. Anti-endotoxin compounds and related molecules and methods
US5530113A (en) * 1991-10-11 1996-06-25 Eisai Co., Ltd. Anti-endotoxin compounds
WO1993011139A1 (fr) * 1991-11-27 1993-06-10 Japan Tobacco Inc. Analogue de lipide a substitue en position 6
US6368604B1 (en) 1997-09-26 2002-04-09 University Of Maryland Biotechnology Institute Non-pyrogenic derivatives of lipid A
EP1088553A4 (en) * 1998-05-06 2002-01-30 Ono Pharmaceutical Co IMMUNOSUPPRESSOR CONTAINING GLUCOPYRANOSIS DERIVATIVE AS ACTIVE INGREDIENT
WO2001025254A2 (en) 1999-10-04 2001-04-12 University Of Maryland Biotechnology Institute Novel adjuvant comprising a lipopolysaccharide antagonist
WO2003095842A1 (de) * 2002-05-07 2003-11-20 Emu Unterwasserpumpen Gmbh Antriebsmotor, insbesondere für eine pumpe
WO2003094850A2 (en) * 2002-05-09 2003-11-20 Biomira, Inc. Lipid a and other carbohydrate ligand analogs
WO2005077876A1 (ja) * 2004-01-28 2005-08-25 Idemitsu Kosan Co., Ltd. 長鎖分岐アルキル基含有カルボニル化合物
EP2060588B1 (en) * 2006-09-04 2014-08-06 Daicel Corporation Polysaccharide derivative and separating agent for optical isomer containing the same
EP2678005A4 (en) 2011-02-24 2015-06-10 Oncothyreon Inc GLUCOLOPOPEPTIDE MUC1-BASED VACCINE WITH AN ADJUVANS
WO2013050413A1 (en) 2011-10-03 2013-04-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for obtaining a population of regulatory t cells
CA2972635A1 (en) 2015-01-06 2016-07-14 Immunovaccine Technologies Inc. Lipid a mimics, methods of preparation, and uses thereof
WO2019175147A1 (en) 2018-03-12 2019-09-19 Janssen Vaccines & Prevention B.V. Vaccines against intra-abdominal infections
JP2022550884A (ja) 2019-10-02 2022-12-05 ヤンセン ファッシンズ アンド プリベンション ベーフェー スタフィロコッカス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ）ペプチドおよび使用方法
JP7485771B2 (ja) 2020-01-16 2024-05-16 ヤンセン ファーマシューティカルズ，インコーポレーテッド ＦｉｍＨ変異体、その組成物、及びその使用
MX2023008251A (es) 2021-01-12 2023-07-26 Janssen Pharmaceuticals Inc Mutantes de fimh, composiciones con estos y uso de estos.
UY39710A (es) 2021-04-01 2022-09-30 Janssen Pharmaceuticals Inc Producción de bioconjugados de o18 de e. coli

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60501259A (ja) * 1983-05-06 1985-08-08 ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン 免疫刺激活性をもつ単糖類化合物
JPS61126094A (ja) * 1984-11-26 1986-06-13 Toho Yakuhin Kogyo Kk リピドａの非還元側サブユニツト類縁体
JPS61126093A (ja) * 1984-11-26 1986-06-13 Toho Yakuhin Kogyo Kk リピドａの非還元側サブユニツト類縁体
JPS61172867A (ja) * 1985-01-29 1986-08-04 Toho Yakuhin Kogyo Kk リピドａの非還元側サブユニツトの類縁化合物
GR860379B (en) * 1985-02-22 1986-06-11 Akzo Nv Novel disaccharide and trisaccharide derivatives of the lipid a type
JPS61275299A (ja) * 1985-05-29 1986-12-05 Akira Hasegawa デオキシムラミルジペプチド誘導体
JPS62108895A (ja) * 1985-11-06 1987-05-20 Fuji Yakuhin Kogyo Kk 新規なグルコサミン誘導体
JPS6344588A (ja) * 1986-08-11 1988-02-25 Toho Yakuhin Kogyo Kk リピドａ単糖類縁体のレクタス型異性体
JPS6330495A (ja) * 1986-07-24 1988-02-09 Toho Yakuhin Kogyo Kk リピドａ単糖類縁体の立体異性体
US4746742A (en) * 1985-11-28 1988-05-24 Toho Yakuhin Kogyo Kabushiki Kaisha Analogs of nonreducing monosaccharide moiety of lipid A
JPS62129292A (ja) * 1985-11-28 1987-06-11 Toho Yakuhin Kogyo Kk 生物活性を発現するリピドａ単糖類縁体
JPS62129293A (ja) * 1985-11-28 1987-06-11 Toho Yakuhin Kogyo Kk 親水性のリピドａ単糖類縁体
JPS63179885A (ja) * 1985-12-06 1988-07-23 Ono Pharmaceut Co Ltd 新規なグリコピラノース誘導体
JPS6333391A (ja) * 1986-07-28 1988-02-13 Toho Yakuhin Kogyo Kk 新規なリピドａ単糖類縁体としての硫黄誘導体
EP0288888B1 (en) * 1987-05-01 1993-12-08 Ono Pharmaceutical Co., Ltd. Novel glucopyranose derivatives
JPH01146892A (ja) * 1987-12-03 1989-06-08 Toho Yakuhin Kogyo Kk 新規ホスホリルグルコサミン誘導体
JPH0225494A (ja) * 1988-07-12 1990-01-26 Akira Hasegawa グルコサミン誘導体
JPH0262888A (ja) * 1988-08-30 1990-03-02 Akira Hasegawa 新規なグルコサミン類
JPH0262889A (ja) * 1988-08-30 1990-03-02 Akira Hasegawa 新規なグルコサミン誘導体

Also Published As

Publication number Publication date
KR940005344B1 (ko) 1994-06-17
CA2042053C (en) 1993-08-10
JPH0655749B2 (ja) 1994-07-27
EP0444208A1 (en) 1991-09-04
JPH03106894A (ja) 1991-05-07
EP0444208A4 (en) 1992-03-11
CA2042053A1 (en) 1993-08-10
US5191072A (en) 1993-03-02
WO1991004259A1 (fr) 1991-04-04

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E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee