KR920701220A - 신규의 복핵 백금 착체 및 이를 유효성분으로하는 항종양제 - Google Patents
신규의 복핵 백금 착체 및 이를 유효성분으로하는 항종양제Info
- Publication number
- KR920701220A KR920701220A KR1019900701840A KR900701840A KR920701220A KR 920701220 A KR920701220 A KR 920701220A KR 1019900701840 A KR1019900701840 A KR 1019900701840A KR 900701840 A KR900701840 A KR 900701840A KR 920701220 A KR920701220 A KR 920701220A
- Authority
- KR
- South Korea
- Prior art keywords
- platinum complex
- binuclear platinum
- same
- structural formula
- following structural
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title claims 14
- 229910052697 platinum Inorganic materials 0.000 title claims 7
- 239000002246 antineoplastic agent Substances 0.000 title claims 5
- 239000004480 active ingredient Substances 0.000 claims 4
- HRGDZIGMBDGFTC-UHFFFAOYSA-N platinum(2+) Chemical compound [Pt+2] HRGDZIGMBDGFTC-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 단일 결정 X-선 구조에 분석에 기초한 본 발명의 화합물의 분자 아디어그램임.
Claims (8)
- 다음 구조식(Ⅰ)을 갖는 복핵 백금 착체
- 다음 구조식(Ⅱ)를 갖는 복핵 백금 착체
- 다음 구조식(Ⅲ)을 갖는 복핵 백금 착체
- 디-μ-술포아세테이토-비스〔(시스-디아미노시클로헥산)백금(Ⅱ)〕.
- 다음 구조식을 갖는 복핵 백금 착체를 유효성분으로서 함유하는 항종양제.
- 다음 구조식을 갖는 복핵 백금 착체를 유효성분으로서 함유하는 항종양제.
- 다음 구조식을 갖는 복핵 백금 착체를 유효성분으로서 함유하는 항종양제.
- 디-μ-술포아세테이토-비스-〔(시스-디아미노시클로헥산)백금(Ⅱ)〕를 유효성분으로서 함유하는 항종양제.※참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63-335306 | 1988-12-29 | ||
| JP33530688 | 1988-12-29 | ||
| JP1246570A JPH02275891A (ja) | 1988-12-29 | 1989-09-25 | 新規な複核白金錯体および該錯体を有効成分とする抗腫瘍剤 |
| JP1-246570 | 1989-09-25 | ||
| PCT/JP1989/001327 WO1990007514A1 (en) | 1988-12-29 | 1989-12-28 | New binuclear platinum complex and antineoplastic agent containing same as active ingredient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR920701220A true KR920701220A (ko) | 1992-08-11 |
Family
ID=26537797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900701840A KR920701220A (ko) | 1988-12-29 | 1989-12-28 | 신규의 복핵 백금 착체 및 이를 유효성분으로하는 항종양제 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5041580A (ko) |
| EP (1) | EP0407603A4 (ko) |
| JP (1) | JPH02275891A (ko) |
| KR (1) | KR920701220A (ko) |
| WO (1) | WO1990007514A1 (ko) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5487008A (en) * | 1990-04-20 | 1996-01-23 | The Regents Of The University Of Michigan | Method and system for detecting the misfire of a reciprocating internal combustion engine in frequency domain |
| DE4415263C1 (de) * | 1994-04-15 | 1995-11-30 | Asta Medica Ag | Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung |
| AU2163797A (en) * | 1996-03-11 | 1997-10-01 | Debiopharm S.A. | Binuclear platinum complexes, method for preparing same and pharmaceutical compositions containing said complexes |
| WO2008120690A1 (ja) * | 2007-03-29 | 2008-10-09 | Osaka University | 光学活性有機酸架橋二核白金（ｉｉ）錯体 |
| RU2008106419A (ru) * | 2008-02-21 | 2009-08-27 | Закрытое акционерное общество "Ива фарм" (RU) | Лекарственные средства на основе олигоядерных координационных соединений d-металлов, способ терапевтического воздействия на организм пациента и способ повышения терапевтической эффективности фармакологически активного вещества |
| RU2417999C2 (ru) | 2009-07-13 | 2011-05-10 | Закрытое Акционерное Общество "Ива Фарм" | БИЯДЕРНЫЕ КООРДИНАЦИОННЫЕ СОЕДИНЕНИЯ БИОЛОГИЧЕСКИ АКТИВНЫХ d-ЭЛЕМЕНТОВ С АЛИФАТИЧЕСКИМИ ТИОЛАМИ КАК СРЕДСТВА ПОВЫШЕНИЯ ЭФФЕКТИВНОСТИ ЛЕКАРСТВЕННЫХ ПРЕПАРАТОВ |
| KR101317809B1 (ko) | 2011-06-07 | 2013-10-16 | 한미약품 주식회사 | 암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물 |
| KR20140096571A (ko) | 2013-01-28 | 2014-08-06 | 한미약품 주식회사 | 1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법 |
| CN103467397B (zh) * | 2013-08-29 | 2015-01-28 | 山西大学 | 一种双核铂(ii)配合物及其制备方法和应用 |
| CN114621291B (zh) * | 2020-12-14 | 2024-04-16 | 广东阿格蕾雅光电材料有限公司 | 双核金属铂配合物及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4560782A (en) * | 1982-11-19 | 1985-12-24 | Research Corporation | Anti-tumor diplatinum coordination compounds |
| US4533502A (en) * | 1983-02-22 | 1985-08-06 | Rochon Fernande D | Platinum (II) compounds and their preparation |
| US4565884A (en) * | 1983-05-10 | 1986-01-21 | Andrulis Research Corporation | Bis-platinum complexes as antitumor agents |
| DE3432320A1 (de) * | 1984-09-03 | 1986-03-13 | Behringwerke Ag, 3550 Marburg | Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel |
| US4797393A (en) * | 1986-07-25 | 1989-01-10 | University Of Vermont And State Agricultural College | Bis-platinum complexes as chemotherapeutic agents |
-
1989
- 1989-09-25 JP JP1246570A patent/JPH02275891A/ja active Pending
- 1989-12-28 US US07/555,485 patent/US5041580A/en not_active Expired - Fee Related
- 1989-12-28 KR KR1019900701840A patent/KR920701220A/ko not_active Application Discontinuation
- 1989-12-28 WO PCT/JP1989/001327 patent/WO1990007514A1/ja not_active Application Discontinuation
- 1989-12-28 EP EP19900901031 patent/EP0407603A4/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0407603A1 (en) | 1991-01-16 |
| US5041580A (en) | 1991-08-20 |
| WO1990007514A1 (en) | 1990-07-12 |
| EP0407603A4 (en) | 1992-11-04 |
| JPH02275891A (ja) | 1990-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |