KR910018374A - 헤테로사이클 치환된 시클로알카노[b] 디히드로인돌 및 -인돌술폰아미드 - Google Patents

헤테로사이클 치환된 시클로알카노[b] 디히드로인돌 및 -인돌술폰아미드 Download PDF

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Publication number
KR910018374A
KR910018374A KR1019910005656A KR910005656A KR910018374A KR 910018374 A KR910018374 A KR 910018374A KR 1019910005656 A KR1019910005656 A KR 1019910005656A KR 910005656 A KR910005656 A KR 910005656A KR 910018374 A KR910018374 A KR 910018374A
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KR
South Korea
Prior art keywords
carbon atoms
straight
group
branched chain
chain alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019910005656A
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English (en)
Korean (ko)
Inventor
이. 뭘러 율리히
로젠트레터 율리히
니뵈너 율리히
퍼즈본 엘리자베트
비쇼프 에르빈
델베크 한스-게오르크
노르만 페터
제이. 쿠드버트 니겔
피. 프란시스 힐라리
Original Assignee
롤프 브라운, 요아힘 그렘
바이엘 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 롤프 브라운, 요아힘 그렘, 바이엘 악티엔게젤샤프트 filed Critical 롤프 브라운, 요아힘 그렘
Publication of KR910018374A publication Critical patent/KR910018374A/ko
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019910005656A 1990-04-10 1991-04-09 헤테로사이클 치환된 시클로알카노[b] 디히드로인돌 및 -인돌술폰아미드 Withdrawn KR910018374A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909008108A GB9008108D0 (en) 1990-04-10 1990-04-10 Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
GB9008108.4 1990-04-10

Publications (1)

Publication Number Publication Date
KR910018374A true KR910018374A (ko) 1991-11-30

Family

ID=10674203

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910005656A Withdrawn KR910018374A (ko) 1990-04-10 1991-04-09 헤테로사이클 치환된 시클로알카노[b] 디히드로인돌 및 -인돌술폰아미드

Country Status (18)

Country Link
US (1) US5204374A (cg-RX-API-DMAC10.html)
EP (1) EP0451634B1 (cg-RX-API-DMAC10.html)
JP (1) JPH04234846A (cg-RX-API-DMAC10.html)
KR (1) KR910018374A (cg-RX-API-DMAC10.html)
AT (1) ATE102618T1 (cg-RX-API-DMAC10.html)
AU (1) AU632213B2 (cg-RX-API-DMAC10.html)
CA (1) CA2039873A1 (cg-RX-API-DMAC10.html)
DE (1) DE69101330T2 (cg-RX-API-DMAC10.html)
DK (1) DK0451634T3 (cg-RX-API-DMAC10.html)
ES (1) ES2062591T3 (cg-RX-API-DMAC10.html)
GB (1) GB9008108D0 (cg-RX-API-DMAC10.html)
HU (1) HU209645B (cg-RX-API-DMAC10.html)
IE (1) IE64843B1 (cg-RX-API-DMAC10.html)
IL (1) IL97795A (cg-RX-API-DMAC10.html)
NZ (1) NZ237709A (cg-RX-API-DMAC10.html)
PT (1) PT97280A (cg-RX-API-DMAC10.html)
TW (1) TW221995B (cg-RX-API-DMAC10.html)
ZA (1) ZA912609B (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464746A (en) * 1991-12-17 1995-11-07 Abbott Laboratories Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives
JP3292731B2 (ja) * 1993-07-20 2002-06-17 アボツト・ラボラトリーズ カルバゾール及びジベンゾフラン誘導体用のハプテン、トレーサー、免疫原及び抗体
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
EP2423190A1 (en) * 2002-05-16 2012-02-29 Shionogi&Co., Ltd. Compounds Exhibiting PGD 2 Receptor Antagonism
WO2003097042A1 (en) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Pgd2 receptor antagonist
EP1654228B1 (en) 2003-06-10 2008-10-22 Smithkline Beecham Corporation Tetrahydrocarbazole derivatives and their pharmaceutical use
ES2327416T3 (es) 2003-06-12 2009-10-29 Smithkline Beecham Corporation Derivados de tetraidrocarbazol y su uso farmaceutico.
AU2006262283B2 (en) * 2005-06-24 2011-10-13 Eli Lilly And Company Tetrahydrocarbazole derivatives useful as androgen receptor modulators (SARM)
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
UA98777C2 (en) * 2006-11-20 2012-06-25 Эли Лилли Энд Компани Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators
CN101434571B (zh) * 2007-11-13 2012-05-30 杭州容立医药科技有限公司 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法
EA019713B1 (ru) * 2008-05-16 2014-05-30 Эли Лилли Энд Компани ТЕТРАГИДРОЦИКЛОПЕНТА[b]ИНДОЛЬНЫЕ МОДУЛЯТОРЫ РЕЦЕПТОРОВ АНДРОГЕНОВ
EP2300425A4 (en) * 2008-06-24 2012-03-21 Panmira Pharmaceuticals Llc PROSTAGLANDIN D2 RECEPTOR CYCLOALCANEÝBINDLUCK ANTAGONISTS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946021A (en) * 1970-07-23 1976-03-23 Richardson-Merrell Inc. Bis-basic ketones of carbazole
US3975398A (en) * 1973-08-01 1976-08-17 Boehringer Mannheim G.M.B.H. 9-Substituted 3-aminocarbazole compounds
US4464379A (en) * 1981-06-01 1984-08-07 A. Nattermann & Cie Gmbh Indol acetic acid derivatives and anti-inflamatory and related uses thereof
DE3514696A1 (de) * 1985-04-24 1986-11-06 Bayer Ag, 5090 Leverkusen N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US4940719A (en) * 1986-03-27 1990-07-10 Merck Frosst Canada, Inc. Tetrahydrocarbazole esters, pharmaceutical compositions and use
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide

Also Published As

Publication number Publication date
PT97280A (pt) 1992-01-31
DE69101330D1 (de) 1994-04-14
IE64843B1 (en) 1995-09-06
EP0451634A3 (en) 1992-01-02
ATE102618T1 (de) 1994-03-15
DE69101330T2 (de) 1994-06-16
DK0451634T3 (da) 1994-05-02
ES2062591T3 (es) 1994-12-16
TW221995B (cg-RX-API-DMAC10.html) 1994-04-01
IL97795A0 (en) 1992-06-21
JPH04234846A (ja) 1992-08-24
CA2039873A1 (en) 1991-10-11
EP0451634B1 (en) 1994-03-09
EP0451634A2 (en) 1991-10-16
AU632213B2 (en) 1992-12-17
IL97795A (en) 1995-08-31
GB9008108D0 (en) 1990-06-06
NZ237709A (en) 1992-10-28
IE911186A1 (en) 1991-10-23
AU7425291A (en) 1991-10-17
US5204374A (en) 1993-04-20
HUT57205A (en) 1991-11-28
HU209645B (en) 1994-09-28
HU911140D0 (en) 1991-10-28
ZA912609B (en) 1992-01-29

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19910409

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid