ATE102618T1 - Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide. - Google Patents
Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide.Info
- Publication number
- ATE102618T1 ATE102618T1 AT91104943T AT91104943T ATE102618T1 AT E102618 T1 ATE102618 T1 AT E102618T1 AT 91104943 T AT91104943 T AT 91104943T AT 91104943 T AT91104943 T AT 91104943T AT E102618 T1 ATE102618 T1 AT E102618T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- indolesulfonamides
- dihydroindols
- cycloalcano
- heterocyclic ring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909008108A GB9008108D0 (en) | 1990-04-10 | 1990-04-10 | Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE102618T1 true ATE102618T1 (de) | 1994-03-15 |
Family
ID=10674203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91104943T ATE102618T1 (de) | 1990-04-10 | 1991-03-28 | Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5204374A (de) |
| EP (1) | EP0451634B1 (de) |
| JP (1) | JPH04234846A (de) |
| KR (1) | KR910018374A (de) |
| AT (1) | ATE102618T1 (de) |
| AU (1) | AU632213B2 (de) |
| CA (1) | CA2039873A1 (de) |
| DE (1) | DE69101330T2 (de) |
| DK (1) | DK0451634T3 (de) |
| ES (1) | ES2062591T3 (de) |
| GB (1) | GB9008108D0 (de) |
| HU (1) | HU209645B (de) |
| IE (1) | IE64843B1 (de) |
| IL (1) | IL97795A (de) |
| NZ (1) | NZ237709A (de) |
| PT (1) | PT97280A (de) |
| TW (1) | TW221995B (de) |
| ZA (1) | ZA912609B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464746A (en) * | 1991-12-17 | 1995-11-07 | Abbott Laboratories | Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives |
| EP0708767B1 (de) * | 1993-07-20 | 2001-02-14 | Abbott Laboratories | Haptene, tracer, immunogene und antikörper für carbazol - und dibenzofuran - derivate |
| DE19506739A1 (de) * | 1995-02-27 | 1996-08-29 | Bayer Ag | [3-Amino]-tetrahydrocarbazol-propansäureester |
| US7534897B2 (en) | 2002-05-16 | 2009-05-19 | Shionogi & Co., Ltd. | Indole arylsulfonaimide compounds exhibiting PGD 2 receptor antagonism |
| AU2003231513A1 (en) * | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Pgd2 receptor antagonist |
| ES2314446T3 (es) | 2003-06-10 | 2009-03-16 | Smithkline Beecham Corporation | Derivados de tetrahidrocarbazol y su uso farmaceutico. |
| KR20060017544A (ko) | 2003-06-12 | 2006-02-23 | 스미스클라인 비참 코포레이션 | 테트라히드로카르바졸 유도체 및 이의 약제학적 용도 |
| BRPI0611705A2 (pt) * | 2005-06-24 | 2016-11-16 | Lilly Co Eli | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de composto |
| US7662831B2 (en) | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| US7601856B2 (en) | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
| UA98777C2 (en) * | 2006-11-20 | 2012-06-25 | Эли Лилли Энд Компани | Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators |
| CN101434571B (zh) * | 2007-11-13 | 2012-05-30 | 杭州容立医药科技有限公司 | 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法 |
| JP5603327B2 (ja) * | 2008-05-16 | 2014-10-08 | イーライ リリー アンド カンパニー | テトラヒドロシクロペンタ［ｂ］インドールアンドロゲン受容体調節物質 |
| JP2011526281A (ja) * | 2008-06-24 | 2011-10-06 | アミラ ファーマシューティカルズ，インク． | プロスタグランジンｄ２受容体のシクロアルカン［ｂ］インドールアンタゴニスト |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3946021A (en) * | 1970-07-23 | 1976-03-23 | Richardson-Merrell Inc. | Bis-basic ketones of carbazole |
| US3975398A (en) * | 1973-08-01 | 1976-08-17 | Boehringer Mannheim G.M.B.H. | 9-Substituted 3-aminocarbazole compounds |
| US4464379A (en) * | 1981-06-01 | 1984-08-07 | A. Nattermann & Cie Gmbh | Indol acetic acid derivatives and anti-inflamatory and related uses thereof |
| DE3514696A1 (de) * | 1985-04-24 | 1986-11-06 | Bayer Ag, 5090 Leverkusen | N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung |
| DE3631824A1 (de) * | 1986-02-21 | 1988-03-31 | Bayer Ag | Cycloalkano(1.2-b)indol-sulfonamide |
| US4940719A (en) * | 1986-03-27 | 1990-07-10 | Merck Frosst Canada, Inc. | Tetrahydrocarbazole esters, pharmaceutical compositions and use |
| DE3613623A1 (de) * | 1986-04-23 | 1987-10-29 | Bayer Ag | N-dihydroindolylethyl-sulfonamide |
-
1990
- 1990-04-10 GB GB909008108A patent/GB9008108D0/en active Pending
-
1991
- 1991-03-28 EP EP91104943A patent/EP0451634B1/de not_active Expired - Lifetime
- 1991-03-28 AT AT91104943T patent/ATE102618T1/de not_active IP Right Cessation
- 1991-03-28 ES ES91104943T patent/ES2062591T3/es not_active Expired - Lifetime
- 1991-03-28 DK DK91104943.5T patent/DK0451634T3/da active
- 1991-03-28 DE DE69101330T patent/DE69101330T2/de not_active Expired - Fee Related
- 1991-04-03 US US07/679,710 patent/US5204374A/en not_active Expired - Fee Related
- 1991-04-04 JP JP3097906A patent/JPH04234846A/ja active Pending
- 1991-04-05 NZ NZ237709A patent/NZ237709A/en unknown
- 1991-04-05 CA CA002039873A patent/CA2039873A1/en not_active Abandoned
- 1991-04-08 PT PT97280A patent/PT97280A/pt not_active Application Discontinuation
- 1991-04-08 IL IL9779591A patent/IL97795A/en not_active IP Right Cessation
- 1991-04-09 ZA ZA912609A patent/ZA912609B/xx unknown
- 1991-04-09 IE IE118691A patent/IE64843B1/en not_active IP Right Cessation
- 1991-04-09 AU AU74252/91A patent/AU632213B2/en not_active Ceased
- 1991-04-09 HU HU911140A patent/HU209645B/hu not_active IP Right Cessation
- 1991-04-09 TW TW080102639A patent/TW221995B/zh active
- 1991-04-09 KR KR1019910005656A patent/KR910018374A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE911186A1 (en) | 1991-10-23 |
| EP0451634B1 (de) | 1994-03-09 |
| EP0451634A2 (de) | 1991-10-16 |
| AU632213B2 (en) | 1992-12-17 |
| JPH04234846A (ja) | 1992-08-24 |
| AU7425291A (en) | 1991-10-17 |
| DE69101330D1 (de) | 1994-04-14 |
| TW221995B (de) | 1994-04-01 |
| EP0451634A3 (en) | 1992-01-02 |
| HU911140D0 (en) | 1991-10-28 |
| KR910018374A (ko) | 1991-11-30 |
| GB9008108D0 (en) | 1990-06-06 |
| DK0451634T3 (da) | 1994-05-02 |
| IL97795A (en) | 1995-08-31 |
| US5204374A (en) | 1993-04-20 |
| NZ237709A (en) | 1992-10-28 |
| HUT57205A (en) | 1991-11-28 |
| CA2039873A1 (en) | 1991-10-11 |
| ES2062591T3 (es) | 1994-12-16 |
| PT97280A (pt) | 1992-01-31 |
| IL97795A0 (en) | 1992-06-21 |
| DE69101330T2 (de) | 1994-06-16 |
| ZA912609B (en) | 1992-01-29 |
| HU209645B (en) | 1994-09-28 |
| IE64843B1 (en) | 1995-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |