IL97795A - Cilcoalkano [b] dihydroindoles and indolesulfonamides are converted by the heterocycles and their pharmaceutical preparations - Google Patents

Cilcoalkano [b] dihydroindoles and indolesulfonamides are converted by the heterocycles and their pharmaceutical preparations

Info

Publication number
IL97795A
IL97795A IL9779591A IL9779591A IL97795A IL 97795 A IL97795 A IL 97795A IL 9779591 A IL9779591 A IL 9779591A IL 9779591 A IL9779591 A IL 9779591A IL 97795 A IL97795 A IL 97795A
Authority
IL
Israel
Prior art keywords
carbon atoms
formula
group
chain
straight
Prior art date
Application number
IL9779591A
Other languages
English (en)
Hebrew (he)
Other versions
IL97795A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL97795A0 publication Critical patent/IL97795A0/xx
Publication of IL97795A publication Critical patent/IL97795A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9779591A 1990-04-10 1991-04-08 Cilcoalkano [b] dihydroindoles and indolesulfonamides are converted by the heterocycles and their pharmaceutical preparations IL97795A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909008108A GB9008108D0 (en) 1990-04-10 1990-04-10 Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles

Publications (2)

Publication Number Publication Date
IL97795A0 IL97795A0 (en) 1992-06-21
IL97795A true IL97795A (en) 1995-08-31

Family

ID=10674203

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9779591A IL97795A (en) 1990-04-10 1991-04-08 Cilcoalkano [b] dihydroindoles and indolesulfonamides are converted by the heterocycles and their pharmaceutical preparations

Country Status (18)

Country Link
US (1) US5204374A (de)
EP (1) EP0451634B1 (de)
JP (1) JPH04234846A (de)
KR (1) KR910018374A (de)
AT (1) ATE102618T1 (de)
AU (1) AU632213B2 (de)
CA (1) CA2039873A1 (de)
DE (1) DE69101330T2 (de)
DK (1) DK0451634T3 (de)
ES (1) ES2062591T3 (de)
GB (1) GB9008108D0 (de)
HU (1) HU209645B (de)
IE (1) IE64843B1 (de)
IL (1) IL97795A (de)
NZ (1) NZ237709A (de)
PT (1) PT97280A (de)
TW (1) TW221995B (de)
ZA (1) ZA912609B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464746A (en) * 1991-12-17 1995-11-07 Abbott Laboratories Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives
EP0708767B1 (de) * 1993-07-20 2001-02-14 Abbott Laboratories Haptene, tracer, immunogene und antikörper für carbazol - und dibenzofuran - derivate
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
US7534897B2 (en) 2002-05-16 2009-05-19 Shionogi & Co., Ltd. Indole arylsulfonaimide compounds exhibiting PGD 2 receptor antagonism
AU2003231513A1 (en) * 2002-05-16 2003-12-02 Shionogi And Co., Ltd. Pgd2 receptor antagonist
ES2314446T3 (es) 2003-06-10 2009-03-16 Smithkline Beecham Corporation Derivados de tetrahidrocarbazol y su uso farmaceutico.
KR20060017544A (ko) 2003-06-12 2006-02-23 스미스클라인 비참 코포레이션 테트라히드로카르바졸 유도체 및 이의 약제학적 용도
BRPI0611705A2 (pt) * 2005-06-24 2016-11-16 Lilly Co Eli composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de composto
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
UA98777C2 (en) * 2006-11-20 2012-06-25 Эли Лилли Энд Компани Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators
CN101434571B (zh) * 2007-11-13 2012-05-30 杭州容立医药科技有限公司 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法
JP5603327B2 (ja) * 2008-05-16 2014-10-08 イーライ リリー アンド カンパニー テトラヒドロシクロペンタ[b]インドールアンドロゲン受容体調節物質
JP2011526281A (ja) * 2008-06-24 2011-10-06 アミラ ファーマシューティカルズ,インク. プロスタグランジンd2受容体のシクロアルカン[b]インドールアンタゴニスト

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946021A (en) * 1970-07-23 1976-03-23 Richardson-Merrell Inc. Bis-basic ketones of carbazole
US3975398A (en) * 1973-08-01 1976-08-17 Boehringer Mannheim G.M.B.H. 9-Substituted 3-aminocarbazole compounds
US4464379A (en) * 1981-06-01 1984-08-07 A. Nattermann & Cie Gmbh Indol acetic acid derivatives and anti-inflamatory and related uses thereof
DE3514696A1 (de) * 1985-04-24 1986-11-06 Bayer Ag, 5090 Leverkusen N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US4940719A (en) * 1986-03-27 1990-07-10 Merck Frosst Canada, Inc. Tetrahydrocarbazole esters, pharmaceutical compositions and use
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide

Also Published As

Publication number Publication date
IE911186A1 (en) 1991-10-23
EP0451634B1 (de) 1994-03-09
EP0451634A2 (de) 1991-10-16
AU632213B2 (en) 1992-12-17
JPH04234846A (ja) 1992-08-24
AU7425291A (en) 1991-10-17
DE69101330D1 (de) 1994-04-14
TW221995B (de) 1994-04-01
EP0451634A3 (en) 1992-01-02
HU911140D0 (en) 1991-10-28
KR910018374A (ko) 1991-11-30
GB9008108D0 (en) 1990-06-06
DK0451634T3 (da) 1994-05-02
US5204374A (en) 1993-04-20
NZ237709A (en) 1992-10-28
HUT57205A (en) 1991-11-28
CA2039873A1 (en) 1991-10-11
ES2062591T3 (es) 1994-12-16
PT97280A (pt) 1992-01-31
ATE102618T1 (de) 1994-03-15
IL97795A0 (en) 1992-06-21
DE69101330T2 (de) 1994-06-16
ZA912609B (en) 1992-01-29
HU209645B (en) 1994-09-28
IE64843B1 (en) 1995-09-06

Similar Documents

Publication Publication Date Title
US5204374A (en) Cycloalkano(b)dihydroindoles and -indolesulphonamides substituted by heterocycles
KR100567148B1 (ko) 치환된 n-[(아미노이미노메틸 또는 아미노메틸)페닐]프로필 아미드 및 이를 함유하는 약제학적 조성물
US5416099A (en) Fibrinogen receptor antagonists
JP3076003B2 (ja) 置換された4−(キノリン−2−イル−メトキシ)フエニル酢酸誘導体及びその塩
JP4615826B2 (ja) 置換インドールおよびインテグリンアンタゴニストとしてのそれらの使用
US8143304B2 (en) (3-amino-1,2,3,4-tetrahydro-9 H-carbazol-9-yl)-acetic acid derivatives
AU2002243692A1 (en) Substituted indoles and their use as integrin antagonists
US5223517A (en) Heterocyclically substituted cycloalkano[b]-indolesulphonamides
JPH10500425A (ja) 薬学的なジケトピペラジン化合物
EA001280B1 (ru) Замещенные n-[(аминоиминометил или аминометил)фенил] пропиламиды
US5039670A (en) Antithrombotic substituted cycloalkano(B)dihydroindole- and -indole-sulphonamides and use
JP3162572B2 (ja) インドロイルグアニジン誘導体
US5155121A (en) Phenylsulphonamide substituted pyridinealkene- and aminooxyalkanecarboxylic acid derivatives
AU655868B2 (en) New pyrrolidine compounds, process for preparing them and pharmaceutical compositions containing them
HU193909B (en) Process for preparing novel 1-4-dihydropyridine-carboxamide derivatives and pharmaceutics comprising these compounds
US5185348A (en) Phenylsulphonamide substituted pyridinealkene- and -aminooxyalkanecarboxylic acid derivatives
HU216829B (hu) Kétszeresen kondenzált pirrolcsoporttal helyettesített fenil-ciklohexán-karbonsav-származékok és az ezeket tartalmazó gyógyszerkészítmények, valamint eljárás előállításukra
NZ245519A (en) Pyrrolidine-substituted alkanoic and alkenoic acids and esters and pharmaceutical compositions
KR100235161B1 (ko) 2-옥소인돌린 유도체
NZ245327A (en) Quinolylmethoxyphenyl-acetamides, preparation and pharmaceutical compositions thereof

Legal Events

Date Code Title Description
RH Patent void