KR890003000B1 - 이미다조[1,2-a]피리미딘의 제조방법 - Google Patents

이미다조[1,2-a]피리미딘의 제조방법 Download PDF

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Publication number
KR890003000B1
KR890003000B1 KR1019830003982A KR830003982A KR890003000B1 KR 890003000 B1 KR890003000 B1 KR 890003000B1 KR 1019830003982 A KR1019830003982 A KR 1019830003982A KR 830003982 A KR830003982 A KR 830003982A KR 890003000 B1 KR890003000 B1 KR 890003000B1
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KR
South Korea
Prior art keywords
group
formula
compound
alkyl
cycloalkyl
Prior art date
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Expired
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KR1019830003982A
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English (en)
Korean (ko)
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KR840005812A (ko
Inventor
윌프레드 로저 틀리
Original Assignee
로우셀 우크라프
허버트 후리텔
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Priority claimed from GB838303612A external-priority patent/GB8303612D0/en
Application filed by 로우셀 우크라프, 허버트 후리텔 filed Critical 로우셀 우크라프
Publication of KR840005812A publication Critical patent/KR840005812A/ko
Application granted granted Critical
Publication of KR890003000B1 publication Critical patent/KR890003000B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019830003982A 1982-08-27 1983-08-25 이미다조[1,2-a]피리미딘의 제조방법 Expired KR890003000B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB8224606 1982-08-27
GB24606 1982-08-27
GB8224606 1982-08-27
GB03612 1983-02-09
GB838303612A GB8303612D0 (en) 1983-02-09 1983-02-09 Imidazo 1,2-a pyrimidines

Publications (2)

Publication Number Publication Date
KR840005812A KR840005812A (ko) 1984-11-19
KR890003000B1 true KR890003000B1 (ko) 1989-08-18

Family

ID=26283682

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830003982A Expired KR890003000B1 (ko) 1982-08-27 1983-08-25 이미다조[1,2-a]피리미딘의 제조방법

Country Status (19)

Country Link
US (2) US4532243A (enExample)
EP (1) EP0104104B1 (enExample)
KR (1) KR890003000B1 (enExample)
AR (1) AR241020A1 (enExample)
AU (1) AU559419B2 (enExample)
CA (1) CA1228589A (enExample)
DD (1) DD215550A5 (enExample)
DE (1) DE3366467D1 (enExample)
DK (1) DK390583A (enExample)
ES (1) ES8506314A1 (enExample)
FI (1) FI74010C (enExample)
GB (1) GB2128989B (enExample)
GR (1) GR79375B (enExample)
IE (1) IE55900B1 (enExample)
IL (1) IL69417A (enExample)
NZ (1) NZ205387A (enExample)
PH (1) PH20037A (enExample)
PT (1) PT77258B (enExample)
SU (1) SU1287752A3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
GB8334210D0 (en) * 1983-12-22 1984-02-01 Roussel Lab Ltd Imidazo(1 2-c)pyrimidines
GB8432073D0 (en) * 1984-12-19 1985-01-30 Roussel Lab Ltd Chemical compounds
GB8613591D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
GB8620060D0 (en) * 1986-08-18 1986-10-01 Roussel Lab Ltd Chemical compounds
US4731446A (en) * 1987-05-01 1988-03-15 The Dow Chemical Company Imidazo[1,2-a]pyrimidine sulfonic acids and acid halides
GB8712466D0 (en) * 1987-05-27 1987-07-01 Roussel Lab Ltd Chemical compounds
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
US5302586A (en) * 1991-12-19 1994-04-12 G. D. Searle & Co. Phosphonomethyl-imidazo[1,2-a]pyrimidine-2-carboxylic acid compounds for treatment of neurotoxic injury
HRP20030675A2 (en) * 2001-01-26 2004-08-31 Bristol Myers Squibb Co Imidazolyl derivatives as corticotropin relasing factor inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
FR2502622A1 (fr) * 1981-03-25 1982-10-01 Synthelabo Derives d'imidazo (1,2-a) pyrimidines, leur preparation et leur application en therapeutique
US4374988A (en) * 1981-11-05 1983-02-22 American Cyanamid Company 4-Heteroarylimidazo-[1,5-A]pyrimidines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4588720A (en) 1986-05-13
IL69417A0 (en) 1983-11-30
AU1846183A (en) 1984-03-01
DK390583D0 (da) 1983-08-26
IE832001L (en) 1984-02-27
FI833055L (fi) 1984-02-28
AR241020A2 (es) 1991-04-30
PH20037A (en) 1986-09-04
DD215550A5 (de) 1984-11-14
FI74010C (fi) 1987-12-10
ES525186A0 (es) 1985-07-01
EP0104104B1 (fr) 1986-09-24
US4532243A (en) 1985-07-30
GR79375B (enExample) 1984-10-22
KR840005812A (ko) 1984-11-19
GB8322993D0 (en) 1983-09-28
IE55900B1 (en) 1991-02-14
PT77258B (en) 1986-03-21
FI74010B (fi) 1987-08-31
AU559419B2 (en) 1987-03-12
IL69417A (en) 1987-12-20
AR241020A1 (es) 1991-04-30
PT77258A (en) 1983-09-01
FI833055A0 (fi) 1983-08-26
DE3366467D1 (en) 1986-10-30
EP0104104A1 (fr) 1984-03-28
ES8506314A1 (es) 1985-07-01
GB2128989B (en) 1986-03-19
SU1287752A3 (ru) 1987-01-30
NZ205387A (en) 1986-06-11
DK390583A (da) 1984-02-28
GB2128989A (en) 1984-05-10
CA1228589A (en) 1987-10-27

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