NZ205387A - Substituted imidazo(1,2-a)pyrimidine derivatives,methods for their preparation and pharmaceutical compositions - Google Patents

Substituted imidazo(1,2-a)pyrimidine derivatives,methods for their preparation and pharmaceutical compositions

Info

Publication number
NZ205387A
NZ205387A NZ205387A NZ20538783A NZ205387A NZ 205387 A NZ205387 A NZ 205387A NZ 205387 A NZ205387 A NZ 205387A NZ 20538783 A NZ20538783 A NZ 20538783A NZ 205387 A NZ205387 A NZ 205387A
Authority
NZ
New Zealand
Prior art keywords
formula
group
compound
compounds
phenylmethanone
Prior art date
Application number
NZ205387A
Other languages
English (en)
Inventor
W R Tully
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838303612A external-priority patent/GB8303612D0/en
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NZ205387A publication Critical patent/NZ205387A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NZ205387A 1982-08-27 1983-08-26 Substituted imidazo(1,2-a)pyrimidine derivatives,methods for their preparation and pharmaceutical compositions NZ205387A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8224606 1982-08-27
GB838303612A GB8303612D0 (en) 1983-02-09 1983-02-09 Imidazo 1,2-a pyrimidines

Publications (1)

Publication Number Publication Date
NZ205387A true NZ205387A (en) 1986-06-11

Family

ID=26283682

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ205387A NZ205387A (en) 1982-08-27 1983-08-26 Substituted imidazo(1,2-a)pyrimidine derivatives,methods for their preparation and pharmaceutical compositions

Country Status (19)

Country Link
US (2) US4532243A (enExample)
EP (1) EP0104104B1 (enExample)
KR (1) KR890003000B1 (enExample)
AR (1) AR241020A1 (enExample)
AU (1) AU559419B2 (enExample)
CA (1) CA1228589A (enExample)
DD (1) DD215550A5 (enExample)
DE (1) DE3366467D1 (enExample)
DK (1) DK390583A (enExample)
ES (1) ES8506314A1 (enExample)
FI (1) FI74010C (enExample)
GB (1) GB2128989B (enExample)
GR (1) GR79375B (enExample)
IE (1) IE55900B1 (enExample)
IL (1) IL69417A (enExample)
NZ (1) NZ205387A (enExample)
PH (1) PH20037A (enExample)
PT (1) PT77258B (enExample)
SU (1) SU1287752A3 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
GB8334210D0 (en) * 1983-12-22 1984-02-01 Roussel Lab Ltd Imidazo(1 2-c)pyrimidines
GB8432073D0 (en) * 1984-12-19 1985-01-30 Roussel Lab Ltd Chemical compounds
GB8613591D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
GB8620060D0 (en) * 1986-08-18 1986-10-01 Roussel Lab Ltd Chemical compounds
US4731446A (en) * 1987-05-01 1988-03-15 The Dow Chemical Company Imidazo[1,2-a]pyrimidine sulfonic acids and acid halides
GB8712466D0 (en) * 1987-05-27 1987-07-01 Roussel Lab Ltd Chemical compounds
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
US5302586A (en) * 1991-12-19 1994-04-12 G. D. Searle & Co. Phosphonomethyl-imidazo[1,2-a]pyrimidine-2-carboxylic acid compounds for treatment of neurotoxic injury
HRP20030675A2 (en) * 2001-01-26 2004-08-31 Bristol Myers Squibb Co Imidazolyl derivatives as corticotropin relasing factor inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
FR2502622A1 (fr) * 1981-03-25 1982-10-01 Synthelabo Derives d'imidazo (1,2-a) pyrimidines, leur preparation et leur application en therapeutique
US4374988A (en) * 1981-11-05 1983-02-22 American Cyanamid Company 4-Heteroarylimidazo-[1,5-A]pyrimidines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US4588720A (en) 1986-05-13
IL69417A0 (en) 1983-11-30
AU1846183A (en) 1984-03-01
DK390583D0 (da) 1983-08-26
IE832001L (en) 1984-02-27
FI833055L (fi) 1984-02-28
AR241020A2 (es) 1991-04-30
KR890003000B1 (ko) 1989-08-18
PH20037A (en) 1986-09-04
DD215550A5 (de) 1984-11-14
FI74010C (fi) 1987-12-10
ES525186A0 (es) 1985-07-01
EP0104104B1 (fr) 1986-09-24
US4532243A (en) 1985-07-30
GR79375B (enExample) 1984-10-22
KR840005812A (ko) 1984-11-19
GB8322993D0 (en) 1983-09-28
IE55900B1 (en) 1991-02-14
PT77258B (en) 1986-03-21
FI74010B (fi) 1987-08-31
AU559419B2 (en) 1987-03-12
IL69417A (en) 1987-12-20
AR241020A1 (es) 1991-04-30
PT77258A (en) 1983-09-01
FI833055A0 (fi) 1983-08-26
DE3366467D1 (en) 1986-10-30
EP0104104A1 (fr) 1984-03-28
ES8506314A1 (es) 1985-07-01
GB2128989B (en) 1986-03-19
SU1287752A3 (ru) 1987-01-30
DK390583A (da) 1984-02-28
GB2128989A (en) 1984-05-10
CA1228589A (en) 1987-10-27

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