KR880001234B1 - N-아세틸뉴라민산염의 제조 방법 - Google Patents

N-아세틸뉴라민산염의 제조 방법 Download PDF

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Publication number
KR880001234B1
KR880001234B1 KR1019850006606A KR850006606A KR880001234B1 KR 880001234 B1 KR880001234 B1 KR 880001234B1 KR 1019850006606 A KR1019850006606 A KR 1019850006606A KR 850006606 A KR850006606 A KR 850006606A KR 880001234 B1 KR880001234 B1 KR 880001234B1
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KR
South Korea
Prior art keywords
acetylneuraminic acid
acetylneuraminate
expectorant
ammonium
cilia
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Expired
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KR1019850006606A
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English (en)
Korean (ko)
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KR860002525A (ko
Inventor
사다노리 오가사와라
다카시 하나후사
가쯔히데 가리야
마사요시 이토오
요시야스 시도리
Original Assignee
메쿠토 가부시기 가이샤
곤도오 야스노리
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Publication of KR860002525A publication Critical patent/KR860002525A/ko
Application granted granted Critical
Publication of KR880001234B1 publication Critical patent/KR880001234B1/ko
Expired legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019850006606A 1984-09-11 1985-09-10 N-아세틸뉴라민산염의 제조 방법 Expired KR880001234B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59189950A JPS6168418A (ja) 1984-09-11 1984-09-11 去痰薬
JP59-189950 1984-09-11

Publications (2)

Publication Number Publication Date
KR860002525A KR860002525A (ko) 1986-04-26
KR880001234B1 true KR880001234B1 (ko) 1988-07-12

Family

ID=16249907

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850006606A Expired KR880001234B1 (ko) 1984-09-11 1985-09-10 N-아세틸뉴라민산염의 제조 방법

Country Status (14)

Country Link
US (1) US4698332A (https=)
EP (2) EP0177783B1 (https=)
JP (1) JPS6168418A (https=)
KR (1) KR880001234B1 (https=)
CN (1) CN85108388B (https=)
AT (2) ATE94396T1 (https=)
AU (1) AU582584B2 (https=)
CA (1) CA1246452A (https=)
DE (2) DE3587928T2 (https=)
DK (1) DK165046C (https=)
ES (1) ES8606323A1 (https=)
FI (1) FI83963C (https=)
HU (2) HU197515B (https=)
ZA (1) ZA856905B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61289037A (ja) * 1985-06-14 1986-12-19 Mect Corp 新規去痰薬
GB8519416D0 (en) * 1985-08-01 1985-09-04 Unilever Plc Oligosaccharides
JP2573594B2 (ja) * 1987-03-06 1997-01-22 メクト株式会社 Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法
US5843445A (en) * 1987-06-24 1998-12-01 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
JP2517293B2 (ja) * 1987-06-25 1996-07-24 メクト株式会社 細胞、組織修復剤
US5393742A (en) * 1990-08-30 1995-02-28 Mect Corporation Preparation for treating renal disease
US5514665A (en) * 1993-12-30 1996-05-07 University Of British Columbia Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
AUPQ275799A0 (en) * 1999-09-10 1999-10-07 Luminis Pty Limited Recombinant bacterium expressing an oligosaccharide receptor mimic
JP4005115B1 (ja) 2007-02-08 2007-11-07 日本臓器製薬株式会社 疼痛疾患治療剤
US9241896B2 (en) * 2008-12-19 2016-01-26 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
UA110325C2 (en) * 2009-07-03 2015-12-25 Australian Biomedical Company Pty Ltd Medicinal carbohydrates for treating respiratory conditions
CA2805222A1 (en) 2010-07-13 2012-01-19 Ultragenyx Pharmaceutical Inc. Methods and formulations for treating sialic acid deficiencies
HK1201067A1 (en) 2011-10-24 2015-08-21 罕见病药物研发公司 Sialic acid analogs
WO2014151523A1 (en) * 2013-03-15 2014-09-25 Huiru Wang Compositions and products for infectious or inflammatory diseases or conditions
WO2014151526A1 (en) 2013-03-15 2014-09-25 Huiru Wang Biological therapeutics for infection-relating disorders or conditions
AU2015297470B2 (en) * 2014-07-30 2019-05-02 Kyowa Hakko Bio Co., Ltd. Crystal of alkali metal N-acetylneuraminate anhydrate, and process for producing same
JP6671305B2 (ja) * 2015-01-28 2020-03-25 協和発酵バイオ株式会社 Ｎ−アセチルノイラミン酸アンモニウム塩・無水和物の結晶及びその製造方法
US10385085B2 (en) 2015-09-14 2019-08-20 Ultragenyx Pharmaceutical Inc. Crystal forms of sialic acid or salt or solvate thereof
CN109771316B (zh) * 2018-12-29 2022-02-25 中国科学院合肥物质科学研究院 一种提高n-乙酰神经氨酸水溶液稳定性的方法及其应用
CN110606864B (zh) * 2019-10-08 2023-10-10 中国科学院合肥物质科学研究院 一种n-乙酰神经氨酸钙盐晶体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali

Also Published As

Publication number Publication date
EP0429430A2 (en) 1991-05-29
US4698332A (en) 1987-10-06
FI83963B (fi) 1991-06-14
AU582584B2 (en) 1989-04-06
ZA856905B (en) 1986-06-25
FI83963C (fi) 1991-09-25
HU197515B (en) 1989-04-28
DK413785D0 (da) 1985-09-11
JPS6168418A (ja) 1986-04-08
DE3587928D1 (de) 1994-10-27
DE3587587D1 (de) 1993-10-21
HU198733B (en) 1989-11-28
EP0177783A3 (en) 1989-02-22
FI853456L (fi) 1986-03-12
DE3587928T2 (de) 1995-01-26
ATE111738T1 (de) 1994-10-15
DK165046B (da) 1992-10-05
HUT40804A (en) 1987-02-27
DK413785A (da) 1986-03-12
JPS6328411B2 (https=) 1988-06-08
DK165046C (da) 1993-02-22
FI853456A0 (fi) 1985-09-10
ES546840A0 (es) 1986-04-16
CA1246452A (en) 1988-12-13
ES8606323A1 (es) 1986-04-16
DE3587587T2 (de) 1994-03-31
EP0429430A3 (en) 1991-10-23
CN85108388A (zh) 1987-06-03
CN85108388B (zh) 1988-08-24
AU4719985A (en) 1986-03-20
EP0177783B1 (en) 1994-09-21
KR860002525A (ko) 1986-04-26
ATE94396T1 (de) 1993-10-15
EP0177783A2 (en) 1986-04-16
EP0429430B1 (en) 1993-09-15

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