KR870000204B1 - 치환된 테트라하이드로나프탈렌의 제조방법 - Google Patents

치환된 테트라하이드로나프탈렌의 제조방법 Download PDF

Info

Publication number
KR870000204B1
KR870000204B1 KR1019830005431A KR830005431A KR870000204B1 KR 870000204 B1 KR870000204 B1 KR 870000204B1 KR 1019830005431 A KR1019830005431 A KR 1019830005431A KR 830005431 A KR830005431 A KR 830005431A KR 870000204 B1 KR870000204 B1 KR 870000204B1
Authority
KR
South Korea
Prior art keywords
hydroxy
tetrahydro
methyl
compound
benzyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019830005431A
Other languages
English (en)
Korean (ko)
Other versions
KR840007561A (ko
Inventor
제임스 바흐 니콜라스
칼 콘펠드 에드먼드
다니엘 티터스 로버트
Original Assignee
일라이 릴리 앤드 캄파니
아더알 웨일
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 일라이 릴리 앤드 캄파니, 아더알 웨일 filed Critical 일라이 릴리 앤드 캄파니
Publication of KR840007561A publication Critical patent/KR840007561A/ko
Application granted granted Critical
Publication of KR870000204B1 publication Critical patent/KR870000204B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Materials Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1019830005431A 1982-11-16 1983-11-16 치환된 테트라하이드로나프탈렌의 제조방법 Expired KR870000204B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/442,074 US4448990A (en) 1982-11-16 1982-11-16 Hydroxyaminotetralincarboxamides
US442074 1982-11-16

Publications (2)

Publication Number Publication Date
KR840007561A KR840007561A (ko) 1984-12-08
KR870000204B1 true KR870000204B1 (ko) 1987-02-16

Family

ID=23755442

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830005431A Expired KR870000204B1 (ko) 1982-11-16 1983-11-16 치환된 테트라하이드로나프탈렌의 제조방법

Country Status (11)

Country Link
US (1) US4448990A (enExample)
EP (1) EP0109815B1 (enExample)
JP (1) JPS59108748A (enExample)
KR (1) KR870000204B1 (enExample)
CA (1) CA1198122A (enExample)
DE (1) DE3363813D1 (enExample)
DK (1) DK515483D0 (enExample)
GB (1) GB2130209B (enExample)
GR (1) GR79034B (enExample)
HU (1) HU196168B (enExample)
IL (1) IL70158A (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5970653A (ja) * 1982-10-15 1984-04-21 Takeda Chem Ind Ltd 眼圧低下剤
CA2012502A1 (en) * 1989-03-21 1990-09-21 Novartis Ag Initiators for materials which can be polymerized cationically
DE3924365A1 (de) * 1989-07-22 1991-01-24 Boehringer Ingelheim Kg 2-amino-7-carbamoyl-1,2,3,4- tetrahydronaphthaline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
WO1994022495A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
US5763609A (en) * 1996-03-21 1998-06-09 Neurogen Corporation Certain pyrrolo pyridine-3-carboxamides; a new class of gaba brain receptor ligands
SI0923542T1 (en) * 1996-05-31 2004-02-29 Pharmacia & Upjohn Company Aryl substituted cyclic amines as selective dopamine d3 ligands
IT1294931B1 (it) * 1997-09-22 1999-04-23 Sigma Tau Ind Farmaceuti Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella
KR101325519B1 (ko) * 2004-10-14 2013-11-08 애보트 게엠베하 운트 콤파니 카게 도파민 ｄ3 수용체의 조절에 반응하는 장애를 치료하기에적합한 아릴설포닐메틸 또는 아릴설폰아미드 치환된 방향족화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2029509A (en) * 1932-12-23 1936-02-04 Ici Ltd Arylamides of 2,3-hydroxynaphthoic acids
US4163063A (en) * 1976-01-02 1979-07-31 University Of Iowa Research Foundation Aminotetralin adrenergic β-agonists
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat

Also Published As

Publication number Publication date
HU196168B (en) 1988-10-28
GB2130209B (en) 1986-05-29
GR79034B (enExample) 1984-10-02
EP0109815B1 (en) 1986-05-28
EP0109815A1 (en) 1984-05-30
GB2130209A (en) 1984-05-31
DK515483D0 (da) 1983-11-11
GB8330279D0 (en) 1983-12-21
JPS59108748A (ja) 1984-06-23
US4448990A (en) 1984-05-15
IL70158A (en) 1987-03-31
KR840007561A (ko) 1984-12-08
DE3363813D1 (en) 1986-07-03
CA1198122A (en) 1985-12-17
IL70158A0 (en) 1984-02-29

Similar Documents

Publication Publication Date Title
JPH0737460B2 (ja) ピラノインドリジン誘導体及びその製造法
CN113999134B (zh) 一种福莫特罗、其可药用盐及其中间体的制备方法
US5434304A (en) Process for preparing formoterol and related compounds
JPH07316113A (ja) 新規アリールアルキル（チオ）アミド化合物
CZ284256B6 (cs) Nový způsob výroby formoterolu a příbuzných sloučenin
KR870000204B1 (ko) 치환된 테트라하이드로나프탈렌의 제조방법
FR2466465A1 (fr) Derives de d-6-n-propylergolines, leur procede de preparation et compositions pharmaceutiques en contenant
PT85061B (pt) Processo para a preparacao de analogos triciclicos de ergolina contendo a estrutura parcial bcd
US4283401A (en) Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy
JPH02744A (ja) 心臟血管系に対し活性な化合物
DE69002474T2 (de) Carboxyalkyl-ether von 2-Amino-7-hydroxytetralin.
JPH08502483A (ja) 新規なキノキサリンジオン誘導体、それらの製造および使用
EP0008249A2 (fr) Dérivés de fluorènes et fluoranthènes, leur procédé de préparation et leur application en thérapeutique
Gerecke et al. Selective Ether Cleavage in the Aporphine Series. Conversion of (S)‐Bulbocapnine into (S)‐Corytuberine and (S)‐Corydine Methyl Ether
JPH09510207A (ja) エポキシドからのｃｉｓ−１−アミノ−２−アルカノールの位置特異的製法
JPS6017795B2 (ja) 新規エルゴリン誘導体の製造法
US4500545A (en) Hydroxyaminotetralincarboxamides
US3226402A (en) And process of making and using same
JPH0341459B2 (enExample)
IE48295B1 (en) Octahydro-2h-pyrrolo(3,4-g)quinolines
KR830000654B1 (ko) 테트라하이드로-2H-벤조[c]피롤의 제조방법
EP1858844A1 (en) Novel crystalline forms of antidiabetic compounds
KR830000273B1 (ko) 옥타하이드로 피라졸로[3,4-g]퀴놀린의 제조방법
BE884145R (fr) Composes indoliques nouveaux
US3213128A (en) Demethylation process

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19831116

PA0201 Request for examination
PG1501 Laying open of application
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19860929

Patent event code: PE09021S01D

PG1605 Publication of application before grant of patent

Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19870109

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19870428