KR850001916B1 - 아미노-페닐-에탄올 아민의 제조방법 - Google Patents

아미노-페닐-에탄올 아민의 제조방법 Download PDF

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Publication number
KR850001916B1
KR850001916B1 KR7501095A KR750001095A KR850001916B1 KR 850001916 B1 KR850001916 B1 KR 850001916B1 KR 7501095 A KR7501095 A KR 7501095A KR 750001095 A KR750001095 A KR 750001095A KR 850001916 B1 KR850001916 B1 KR 850001916B1
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KR
South Korea
Prior art keywords
ethanol
phenyl
amino
tert
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR7501095A
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English (en)
Korean (ko)
Other versions
KR830000207A (ko
Inventor
엥겔하르트 균터
켁크 요하네스
크류거 케르트
놀 크라우스-라인홀트
피이퍼 헬무트
Original Assignee
에른스트 제에거 프리츠 조메르
독크톨 카르르 로오마에 지엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2261914A external-priority patent/DE2261914C3/de
Priority claimed from DE19732345442 external-priority patent/DE2345442C2/de
Priority claimed from DE19732351281 external-priority patent/DE2351281C3/de
Priority claimed from DE2354961A external-priority patent/DE2354961C2/de
Priority claimed from KR7302145A external-priority patent/KR790000255B1/ko
Application filed by 에른스트 제에거 프리츠 조메르, 독크톨 카르르 로오마에 지엠베하 filed Critical 에른스트 제에거 프리츠 조메르
Publication of KR830000207A publication Critical patent/KR830000207A/ko
Application granted granted Critical
Publication of KR850001916B1 publication Critical patent/KR850001916B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
KR7501095A 1972-12-08 1975-05-19 아미노-페닐-에탄올 아민의 제조방법 Expired KR850001916B1 (ko)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US2261914.3 1972-12-08
DE2261914.3 1972-12-18
DE2261914A DE2261914C3 (de) 1972-12-18 1972-12-18 Amino-phenyl-äthanolamine und deren Säureadditionssalze, Verfahren zu deren Herstellung und Arzneimittel
DE2345442.4 1973-09-08
US2345442.4 1973-09-08
DE19732345442 DE2345442C2 (de) 1973-09-08 1973-09-08 d- und l-Phenyläthanolamine und deren Salze, Herstellungsverfahren und Arzneimittel auf deren Basis
US2351281.4 1973-10-12
DE2351281.4 1973-10-12
DE19732351281 DE2351281C3 (de) 1973-10-12 1973-10-12 Aminophenyl-äthanolamin-Derivate, deren Herstellung und Verwendung
DE2354961A DE2354961C2 (de) 1973-11-02 1973-11-02 Verfahren zur Herstellung von Aminophenyl-äthanolaminen
US2354961.3 1973-11-02
DE2354961.3 1973-11-02
KR7302145A KR790000255B1 (en) 1973-11-02 1973-12-14 Process of manufacturing amino-penyl-ethanolamines

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR7302145A Division KR790000255B1 (en) 1972-12-08 1973-12-14 Process of manufacturing amino-penyl-ethanolamines

Publications (2)

Publication Number Publication Date
KR830000207A KR830000207A (ko) 1983-03-30
KR850001916B1 true KR850001916B1 (ko) 1985-12-31

Family

ID=27431596

Family Applications (1)

Application Number Title Priority Date Filing Date
KR7501095A Expired KR850001916B1 (ko) 1972-12-08 1975-05-19 아미노-페닐-에탄올 아민의 제조방법

Country Status (20)

Country Link
JP (1) JPS5811852B2 (enrdf_load_stackoverflow)
KR (1) KR850001916B1 (enrdf_load_stackoverflow)
BG (1) BG21209A3 (enrdf_load_stackoverflow)
CA (1) CA1027955A (enrdf_load_stackoverflow)
CH (2) CH605622A5 (enrdf_load_stackoverflow)
DD (1) DD111574A5 (enrdf_load_stackoverflow)
DK (1) DK150502C (enrdf_load_stackoverflow)
FI (1) FI62052C (enrdf_load_stackoverflow)
FR (1) FR2210414B1 (enrdf_load_stackoverflow)
GB (1) GB1445740A (enrdf_load_stackoverflow)
HK (1) HK6680A (enrdf_load_stackoverflow)
HU (1) HU168701B (enrdf_load_stackoverflow)
IE (1) IE39065B1 (enrdf_load_stackoverflow)
IL (1) IL43837A (enrdf_load_stackoverflow)
MY (1) MY8800145A (enrdf_load_stackoverflow)
NL (1) NL176168C (enrdf_load_stackoverflow)
NO (1) NO137782C (enrdf_load_stackoverflow)
PL (1) PL97194B1 (enrdf_load_stackoverflow)
RO (1) RO63025A (enrdf_load_stackoverflow)
SE (1) SE409700B (enrdf_load_stackoverflow)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2430486A1 (fr) * 1978-07-07 1980-02-01 Oreal Conditionnement d'un produit desinfectant et desodorisant pour cuvette de toilettes
NL8105170A (nl) * 1980-12-10 1982-07-01 Thomae Gmbh Dr K Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen.
FR2515177A1 (fr) * 1981-10-28 1983-04-29 Lafon Labor Nouveaux derives de 1-(aminophenyl)-2-amino-1-ethanol, leur procede de preparation et leur utilisation en therapeutique
US4943591A (en) * 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
GB8426191D0 (en) * 1984-10-17 1984-11-21 Glaxo Holdings Ltd Chemical compounds
EP0224001B1 (en) * 1985-10-17 1991-03-20 American Cyanamid Company Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
US4863959A (en) * 1985-10-17 1989-09-05 American Cyanamid Company Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals
GB8603475D0 (en) * 1986-02-12 1986-03-19 Glaxo Group Ltd Chemical compounds
GB8703007D0 (en) * 1987-02-10 1987-03-18 Glaxo Group Ltd Chemical compounds
EP0278727A3 (en) * 1987-02-10 1990-03-14 Glaxo Group Limited 1-(4-amino-3-chloro-5-trifluoromethylphenyl)-2-(substituted amino)ethanol derivatives and their use in the treatment of respiratory disease
SG119954A1 (en) * 2003-08-29 2006-03-28 Mitsui Chemicals Inc Insecticide for agricultural or horticultural use and method of use thereof
GB0604822D0 (en) * 2006-03-09 2006-04-19 Arakis Ltd The treatment of inflammatory disorders and pain
CN100497296C (zh) * 2006-07-07 2009-06-10 沈阳药科大学 旋光活性的苯乙醇胺类化合物及其制法
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods

Also Published As

Publication number Publication date
FR2210414B1 (enrdf_load_stackoverflow) 1977-01-28
MY8800145A (en) 1988-12-31
FR2210414A1 (enrdf_load_stackoverflow) 1974-07-12
IL43837A (en) 1977-02-28
DK150502B (da) 1987-03-16
NO137782B (no) 1978-01-16
DK150502C (da) 1987-10-26
FI62052B (fi) 1982-07-30
JPS5811852B2 (ja) 1983-03-04
AU6369373A (en) 1975-06-19
BG21209A3 (bg) 1976-03-20
PL97194B1 (pl) 1978-02-28
GB1445740A (en) 1976-08-11
RO63025A (fr) 1978-12-15
CH614188A5 (en) 1979-11-15
SE409700B (sv) 1979-09-03
DD111574A5 (enrdf_load_stackoverflow) 1975-02-20
IE39065B1 (en) 1978-08-02
NO137782C (no) 1978-04-26
NL176168B (nl) 1984-10-01
HU168701B (enrdf_load_stackoverflow) 1976-06-28
FI62052C (fi) 1982-11-10
CH605622A5 (enrdf_load_stackoverflow) 1978-10-13
JPS4994640A (enrdf_load_stackoverflow) 1974-09-09
IL43837A0 (en) 1974-03-14
CA1027955A (en) 1978-03-14
NL7316139A (enrdf_load_stackoverflow) 1974-06-20
IE39065L (en) 1974-06-18
NL176168C (nl) 1985-03-01
KR830000207A (ko) 1983-03-30
HK6680A (en) 1980-03-07

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Legal Events

Date Code Title Description
PA0107 Divisional application

Comment text: Divisional Application of Patent

Patent event date: 19750519

Patent event code: PA01071R01D

Filing date: 19731214

Application number text: 1019730002145

PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19791204

Patent event code: PE09021S01D

PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19800619

Patent event code: PE09021S01D

PE0601 Decision on rejection of patent

Patent event date: 19810328

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19800619

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

Patent event date: 19791204

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19830110

Patent event code: PE09021S01D

PG1501 Laying open of application
PE0601 Decision on rejection of patent

Patent event date: 19830908

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19830110

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

Patent event date: 19800619

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

Patent event date: 19791204

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

PG1605 Publication of application before grant of patent

Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19851210

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19860314