KR840004746A - 2-옥소-1-아제티딘술폰산 유도체의 제조방법 - Google Patents

2-옥소-1-아제티딘술폰산 유도체의 제조방법 Download PDF

Info

Publication number
KR840004746A
KR840004746A KR1019830002380A KR830002380A KR840004746A KR 840004746 A KR840004746 A KR 840004746A KR 1019830002380 A KR1019830002380 A KR 1019830002380A KR 830002380 A KR830002380 A KR 830002380A KR 840004746 A KR840004746 A KR 840004746A
Authority
KR
South Korea
Prior art keywords
group
general formula
carboxy
hydrogen atom
substituted
Prior art date
Application number
KR1019830002380A
Other languages
English (en)
Other versions
KR900005112B1 (ko
Inventor
스스무 나까가와
Original Assignee
이와다레 고이찌
반유세이야꾸 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57091471A external-priority patent/JPS58208288A/ja
Priority claimed from JP4785283A external-priority patent/JPS59175490A/ja
Application filed by 이와다레 고이찌, 반유세이야꾸 가부시기가이샤 filed Critical 이와다레 고이찌
Publication of KR840004746A publication Critical patent/KR840004746A/ko
Application granted granted Critical
Publication of KR900005112B1 publication Critical patent/KR900005112B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

2-옥소-1-아제티딘술폰산 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 하기 일반식(A)로 나타내는 화합물을 하기 일반식(B)의 화합물의 카르복시기를 활성화시켜 생성된 반응성 유도체와 반응시키고, 일반식(A)의 화합물의 R1이 수소원자일때 반응 생성물을 술폰화시키고, 보호기를 제거함을 특징으로 하는 하기 일반식(1)로 나타내는 광학적으로 활성인 화합물 및 약학적으로 허용가능한 그의 염의 제조방법.
    (식중, R은 직쇄 또는 측쇄 C1~C4알킬기, C3~C4알케닐기, C3~C4알키닐기, 카르복시-치환 메틸기, 시아노-치환 메틸기, 카르복시에 의해 치환될 수 있는 C3~C6시클로알킬기, 카르복시-치환 C1~C5알킬기, 벤질기 및 페닐기의 군에서 선택된 기를 나타내며, R1은 수소원자, -SO3H 또는 -SO3H의 무기산염 또는 유기아민염을 나타내고, R2는 수소원자 또는 아미노기에 대한 보호기를 나타내며, R이 카르복시치환체를 갖는다면 R은 카르복시기에 대한 보호기에 의해 보호된다.)
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830002380A 1982-05-31 1983-05-30 2-옥소-1-아제티딘술폰산 유도체의 제조방법 KR900005112B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP91471 1982-05-31
JP57091471A JPS58208288A (ja) 1982-05-31 1982-05-31 ２−オキソ−１−アゼチジンスルホン酸誘導体
JP91,471/82 1982-05-31
JP47852 1983-03-24
JP47,852/83 1983-03-24
JP4785283A JPS59175490A (ja) 1983-03-24 1983-03-24 ２−オキソ−１−アゼチジンスルホン酸誘導体

Publications (2)

Publication Number Publication Date
KR840004746A true KR840004746A (ko) 1984-10-24
KR900005112B1 KR900005112B1 (ko) 1990-07-19

Family

ID=26388054

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002380A KR900005112B1 (ko) 1982-05-31 1983-05-30 2-옥소-1-아제티딘술폰산 유도체의 제조방법

Country Status (6)

Country Link
EP (1) EP0095778B1 (ko)
KR (1) KR900005112B1 (ko)
CA (1) CA1203806A (ko)
DE (1) DE3364927D1 (ko)
HU (1) HU189290B (ko)
SU (1) SU1195908A3 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558467B2 (fr) * 1981-10-23 1987-03-20 Roussel Uclaf Nouveau produit derive de l'acide 3-amino 2-oxo azetidine 1-sulfamique, son procede de preparation, son application comme medicament et un produit intermediaire necessaire a sa preparation
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
EP0096296B1 (de) * 1982-06-03 1987-07-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 1-Sulfo-2-oxoazetidinderivate
GB8504072D0 (en) * 1985-02-18 1985-03-20 Fujisawa Pharmaceutical Co Cephem compounds
FR2585021B2 (fr) * 1985-07-18 1989-05-19 Roussel Uclaf Nouveaux derives de la 3-amino 2-oxoazetidinone comportant, en position 1, un radical heterocyclique azote, leur procede de preparation et leur application comme medicaments
US4684722A (en) * 1986-01-06 1987-08-04 E. R. Squibb & Sons, Inc. Monosulfactams
EP1414088B1 (en) * 2001-07-31 2013-05-22 Tokuyama Corporation Novel onium salt, electrolyte for nonaqueous cell containing the novel onium salt for nonaqueous cell, and method for optimizing a negative electrode using an electrolyte containing the onium salt
PL3122745T3 (pl) 2014-03-24 2019-08-30 Novartis Ag Monobaktamowe związki organiczne do leczenia zakażeń bakteryjnych
DK3353175T3 (da) 2015-09-23 2020-09-14 Novartis Ag Salte og faste former af et monobactam-antibiotikum
WO2019026004A2 (en) 2017-08-02 2019-02-07 Novartis Ag CHEMICAL PROCESS FOR THE PREPARATION OF ANTIBIOTIC MONOBACTAM AND ITS INTERMEDIATES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0021678B1 (en) * 1979-06-08 1984-11-07 Takeda Chemical Industries, Ltd. 1-sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof
EP0048953B1 (en) * 1980-09-29 1988-03-09 E.R. Squibb & Sons, Inc. Beta-lactam antibiotics

Also Published As

Publication number Publication date
EP0095778B1 (en) 1986-07-30
CA1203806A (en) 1986-04-29
DE3364927D1 (en) 1986-09-04
SU1195908A3 (ru) 1985-11-30
EP0095778A1 (en) 1983-12-07
HU189290B (en) 1986-06-30
KR900005112B1 (ko) 1990-07-19

Similar Documents

Publication Publication Date Title
KR850000406A (ko) 4-클로로-2-페닐이미다졸-5-아세트산유도체의 제조방법
KR870001142A (ko) 페닐 에테르의 제법
KR830001947A (ko) 화합물의 제조방법
KR850003402A (ko) 2-아미노-5-하이드록시-4-메틸 피리미딘 유도체의 제조방법
KR840001952A (ko) N-(4-(3-아미노프로필) 아미노부틸)-2-(ω)-과니디노-지방산-아미도)-2-치환된-에탄아미드 이들의 염 및 이들의 제조방법
KR840004746A (ko) 2-옥소-1-아제티딘술폰산 유도체의 제조방법
KR840001145A (ko) 피리다진의 아미노 화합물의 제조방법
KR960701068A (ko) 실릴화 아세틸콜린에스테라제 억제제(Silylated acetylcholinesterase inhibitors)
KR840000563A (ko) 세펨 화합물의 제조방법
KR840002404A (ko) 세포 디짐의 결정성 염의 제조방법
KR890014435A (ko) 페녹시알킬카복실산 유도체 및 이의 제조방법
KR840006254A (ko) 7-치환된-3-비닐-3-세펨화합물의 제조방법
KR830004220A (ko) 약리적 활성 펩티드
KR850001724A (ko) 4-페닐-4-옥소-부텐-2-오인산유도체의 제조방법
KR830004217A (ko) 약학적 활성이 있는 펩타이드
PT83334B (pt) Processo para a preparacao de compostos beta-lactamicos
KR850004470A (ko) 유기 화합물의 제조방법
KR840006238A (ko) 신규 α-아릴-α-피리딜알카노인산 유도체의 제조방법
ATE40117T1 (de) O-substituierte 3-oxypyridiniumsalze, verfahren zu ihrer herstellung und ihre verwendung als fungizide fuer den pflanzenschutz.
KR840008160A (ko) 신규 세팜 화합물 및 그의 제조방법
KR850007800A (ko) 세팔로스포린 유도체의 에스테르 제조방법
KR830001899A (ko) 4-아미노-3-퀴놀린카복실산 및 에스테르-항분비, 항궤양 화합물
KR830001265A (ko) 새로운 티아디아졸 화합물류와 그 제조방법
KR830004311A (ko) 페니실린 화합물의 제조방법
KR940014340A (ko) 3-아자비시클로[3.l.0]헥산-2-온 유도체와 제초제 활성 성분으로 이를 포함하는 제조체 조성물

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee