KR20240074895A - 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 - Google Patents
트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 Download PDFInfo
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- KR20240074895A KR20240074895A KR1020247015927A KR20247015927A KR20240074895A KR 20240074895 A KR20240074895 A KR 20240074895A KR 1020247015927 A KR1020247015927 A KR 1020247015927A KR 20247015927 A KR20247015927 A KR 20247015927A KR 20240074895 A KR20240074895 A KR 20240074895A
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562199563P | 2015-07-31 | 2015-07-31 | |
| US62/199,563 | 2015-07-31 | ||
| US201662287518P | 2016-01-27 | 2016-01-27 | |
| US62/287,518 | 2016-01-27 | ||
| PCT/US2016/044359 WO2017023660A1 (en) | 2015-07-31 | 2016-07-28 | TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED DISEASES |
| KR1020187005958A KR102667020B1 (ko) | 2015-07-31 | 2016-07-28 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187005958A Division KR102667020B1 (ko) | 2015-07-31 | 2016-07-28 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240074895A true KR20240074895A (ko) | 2024-05-28 |
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ID=56682264
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247015927A Pending KR20240074895A (ko) | 2015-07-31 | 2016-07-28 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
| KR1020187005958A Active KR102667020B1 (ko) | 2015-07-31 | 2016-07-28 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187005958A Active KR102667020B1 (ko) | 2015-07-31 | 2016-07-28 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
Country Status (35)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| HUE026604T2 (hu) | 2008-10-20 | 2016-06-28 | Alnylam Pharmaceuticals Inc | Transztiretin-expresszió gátlására szolgáló készítmények és eljárások |
| CA2744987C (en) | 2008-12-02 | 2018-01-16 | Chiralgen, Ltd. | Method for the synthesis of phosphorus atom modified nucleic acids |
| CA2767253A1 (en) | 2009-07-06 | 2011-01-13 | Ontorii, Inc. | Novel nucleic acid prodrugs and methods of use thereof |
| WO2011139917A1 (en) | 2010-04-29 | 2011-11-10 | Isis Pharmaceuticals, Inc. | Modulation of transthyretin expression |
| WO2012039448A1 (ja) | 2010-09-24 | 2012-03-29 | 株式会社キラルジェン | 不斉補助基 |
| WO2013012758A1 (en) | 2011-07-19 | 2013-01-24 | Ontorii, Inc. | Methods for the synthesis of functionalized nucleic acids |
| MX391815B (es) * | 2011-11-18 | 2025-03-21 | Alnylam Pharmaceuticals Inc | AGENTES DE iARN, COMPOSICIONES Y METODOS DE LOS MISMOS PARA USARSE EN EL TRATAMIENTO DE ENFERMEDADES ASOCIADAS CON TRANSTITERINA (TTR). |
| KR102853694B1 (ko) | 2011-11-18 | 2025-09-03 | 알닐람 파마슈티칼스 인코포레이티드 | 변형된 RNAi 제제 |
| JP6268157B2 (ja) | 2012-07-13 | 2018-01-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| KR102712879B1 (ko) | 2012-07-13 | 2024-10-04 | 웨이브 라이프 사이언시스 리미티드 | 키랄 제어 |
| US10144933B2 (en) | 2014-01-15 | 2018-12-04 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
| JPWO2015108048A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| EP4137572A1 (en) | 2014-01-16 | 2023-02-22 | Wave Life Sciences Ltd. | Chiral design |
| KR20240074895A (ko) | 2015-07-31 | 2024-05-28 | 알닐람 파마슈티칼스 인코포레이티드 | 트랜스티레틴(TTR) iRNA 조성물 및 TTR-관련 질병을 치료하거나, 예방하기 위한 그의 사용 방법 |
| JOP20210043A1 (ar) * | 2015-10-01 | 2017-06-16 | Arrowhead Pharmaceuticals Inc | تراكيب وأساليب لتثبيط تعبير جيني للـ lpa |
| TWI865997B (zh) * | 2016-12-16 | 2024-12-11 | 美商阿尼拉製藥公司 | 使用甲狀腺素運載蛋白(TTR)iRNA組成物於治療或預防TTR相關疾病之方法 |
| AU2018336806B2 (en) | 2017-09-19 | 2025-04-10 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for treating transthyretin (TTR) mediated amyloidosis |
| HRP20250277T1 (hr) * | 2017-12-01 | 2025-05-09 | Suzhou Ribo Life Science Co., Ltd. | Dvolančani oligonukleotid, sastav i konjugat koji sadrži dvolančani oligonukleotid, postupak njihove pripreme i upotreba |
| CA3114396A1 (en) | 2018-09-28 | 2020-04-02 | Alnylam Pharmaceuticals, Inc. | Transthyretin (ttr) irna compositions and methods of use thereof for treating or preventing ttr-associated ocular diseases |
| EP4022062A1 (en) | 2019-08-30 | 2022-07-06 | Alnylam Pharmaceuticals, Inc. | Neurofilament light chain (nfl) as a biomarker for transthyretin amyloidosis polyneuropathy |
| CN115461460A (zh) | 2020-03-06 | 2022-12-09 | 阿尔尼拉姆医药品有限公司 | 用于抑制转甲状腺素蛋白(ttr)的表达的组合物和方法 |
| WO2022094152A1 (en) * | 2020-10-28 | 2022-05-05 | Neotope Neuroscience Limited | Anti-transthyretin antibodies and methods of use thereof |
| AU2022242899A1 (en) * | 2021-03-24 | 2023-11-09 | Atalanta Therapeutics, Inc. | Double-stranded sirna having patterned chemical modifications |
| WO2022260939A2 (en) | 2021-06-08 | 2022-12-15 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for treating or preventing stargardt's disease and/or retinal binding protein 4 (rbp4)-associated disorders |
| KR20240042004A (ko) | 2021-08-03 | 2024-04-01 | 알닐람 파마슈티칼스 인코포레이티드 | 트랜스티레틴(TTR) iRNA 조성물 및 이의 사용 방법 |
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| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |