KR20200015608A - Htra1 발현을 조절하기 위한 안티센스 올리고뉴클레오티드 - Google Patents

Htra1 발현을 조절하기 위한 안티센스 올리고뉴클레오티드 Download PDF

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KR20200015608A
KR20200015608A KR1020197038723A KR20197038723A KR20200015608A KR 20200015608 A KR20200015608 A KR 20200015608A KR 1020197038723 A KR1020197038723 A KR 1020197038723A KR 20197038723 A KR20197038723 A KR 20197038723A KR 20200015608 A KR20200015608 A KR 20200015608A
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oligonucleotide
oligonucleotides
htra1
nucleosides
seq
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루벤 알바레즈 산체스
로베르토 이아콘
페테르 하게도른
주잔네 카믈러
쇠렌 오토센
신드리 트라우스타손
하이디 뤠 후들부슈
뤼케 페데르센
마르코 베레라
안드레아스 디에크만
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에프. 호프만-라 로슈 아게
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
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    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2320/32—Special delivery means, e.g. tissue-specific

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  • Ophthalmology & Optometry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020197038723A 2017-06-01 2018-05-30 Htra1 발현을 조절하기 위한 안티센스 올리고뉴클레오티드 Withdrawn KR20200015608A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP17173964.2 2017-06-01
EP17173964 2017-06-01
EP17209407.0 2017-12-21
EP17209535.8 2017-12-21
EP17209535 2017-12-21
EP17209407 2017-12-21
PCT/EP2018/064221 WO2018220034A1 (en) 2017-06-01 2018-05-30 Antisense oligonucleotides for modulating htra1 expression

Publications (1)

Publication Number Publication Date
KR20200015608A true KR20200015608A (ko) 2020-02-12

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KR1020197038723A Withdrawn KR20200015608A (ko) 2017-06-01 2018-05-30 Htra1 발현을 조절하기 위한 안티센스 올리고뉴클레오티드

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US (3) US20190055564A1 (https=)
EP (1) EP3630976A1 (https=)
JP (1) JP7169995B2 (https=)
KR (1) KR20200015608A (https=)
CN (1) CN110691849A (https=)
AU (1) AU2018277219A1 (https=)
BR (1) BR112019025290A2 (https=)
CA (1) CA3062590A1 (https=)
CL (1) CL2019003337A1 (https=)
CO (1) CO2019013317A2 (https=)
CR (1) CR20190543A (https=)
IL (1) IL271039A (https=)
MA (1) MA49278A (https=)
MX (1) MX2019014187A (https=)
PE (1) PE20191845A1 (https=)
PH (1) PH12019502636A1 (https=)
RU (1) RU2019143004A (https=)
TW (1) TW201907008A (https=)
WO (1) WO2018220034A1 (https=)

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AU2017289204A1 (en) 2016-07-01 2019-01-17 F. Hoffmann-La Roche Ag Antisense oligonucleotides for modulating HTRA1 expression
AU2019218987B2 (en) 2018-02-12 2025-04-24 Ionis Pharmaceuticals, Inc. Modified compounds and uses thereof
CN116507741A (zh) * 2020-08-20 2023-07-28 基因组评论股份有限公司 年龄相关性黄斑变性诊断用生物标记物及其用途
CA3199951A1 (en) * 2020-10-30 2022-05-05 Hideaki Hara Gdf15 modulators for use in inhibiting ocular tissue fibrosis

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JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
AU9063398A (en) 1997-09-12 1999-04-05 Exiqon A/S Oligonucleotide analogues
WO2000008134A2 (en) * 1998-08-03 2000-02-17 Novartis Ag HUMAN HtrA SERINE PROTEASE
CZ296576B6 (cs) 1999-02-12 2006-04-12 Sankyo Company Limited Nukleosidový analog a oligonukleotidový analog a farmaceutický prostredek, sonda a primer s jeho obsahem
EP1178999B1 (en) 1999-05-04 2007-03-14 Santaris Pharma A/S L-ribo-lna analogues
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Publication number Publication date
TW201907008A (zh) 2019-02-16
JP7169995B2 (ja) 2022-11-11
CN110691849A (zh) 2020-01-14
EP3630976A1 (en) 2020-04-08
BR112019025290A2 (pt) 2020-06-23
CR20190543A (es) 2020-02-10
PH12019502636A1 (en) 2020-06-08
MA49278A (fr) 2020-04-08
CO2019013317A2 (es) 2020-01-17
MX2019014187A (es) 2020-01-27
PE20191845A1 (es) 2019-12-31
RU2019143004A (ru) 2021-07-09
WO2018220034A1 (en) 2018-12-06
US20200157546A1 (en) 2020-05-21
US20220042022A1 (en) 2022-02-10
CA3062590A1 (en) 2018-12-06
AU2018277219A1 (en) 2019-12-19
IL271039A (en) 2020-01-30
JP2020521491A (ja) 2020-07-27
US20190055564A1 (en) 2019-02-21
CL2019003337A1 (es) 2020-05-15

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Patent event date: 20191230

Patent event code: PA01051R01D

Comment text: International Patent Application

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