KR20170078689A - 췌장암을 치료하기 위한 펩타이드 기반 방법 - Google Patents
췌장암을 치료하기 위한 펩타이드 기반 방법 Download PDFInfo
- Publication number
- KR20170078689A KR20170078689A KR1020177012656A KR20177012656A KR20170078689A KR 20170078689 A KR20170078689 A KR 20170078689A KR 1020177012656 A KR1020177012656 A KR 1020177012656A KR 20177012656 A KR20177012656 A KR 20177012656A KR 20170078689 A KR20170078689 A KR 20170078689A
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- South Korea
- Prior art keywords
- peptide
- pancreatic cancer
- lys
- phe
- gemcitabine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
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- Rheumatology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- AIDS & HIV (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462063909P | 2014-10-14 | 2014-10-14 | |
| US62/063,909 | 2014-10-14 | ||
| PCT/US2015/055305 WO2016061087A1 (en) | 2014-10-14 | 2015-10-13 | Peptide-based methods for treating pancreatic cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20170078689A true KR20170078689A (ko) | 2017-07-07 |
Family
ID=54365375
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177012890A Active KR102478073B1 (ko) | 2014-10-14 | 2015-10-13 | 항-염증 특성을 갖는 펩타이드 |
| KR1020177012656A Ceased KR20170078689A (ko) | 2014-10-14 | 2015-10-13 | 췌장암을 치료하기 위한 펩타이드 기반 방법 |
| KR1020227043575A Ceased KR20230004907A (ko) | 2014-10-14 | 2015-10-13 | 항-염증 특성을 갖는 펩타이드 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177012890A Active KR102478073B1 (ko) | 2014-10-14 | 2015-10-13 | 항-염증 특성을 갖는 펩타이드 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020227043575A Ceased KR20230004907A (ko) | 2014-10-14 | 2015-10-13 | 항-염증 특성을 갖는 펩타이드 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US9492499B2 (enExample) |
| EP (2) | EP3206703B1 (enExample) |
| JP (3) | JP6613312B2 (enExample) |
| KR (3) | KR102478073B1 (enExample) |
| CN (2) | CN107580502B (enExample) |
| AU (2) | AU2015333728B2 (enExample) |
| BR (1) | BR112017007543A2 (enExample) |
| CA (2) | CA2963478A1 (enExample) |
| WO (2) | WO2016061087A1 (enExample) |
| ZA (1) | ZA201702537B (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014100615A1 (en) | 2012-12-20 | 2014-06-26 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| JP6613312B2 (ja) * | 2014-10-14 | 2019-11-27 | ジ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンティッド バイ ザ セクレタリー,デパートメント オブ ヘルス アンド ヒューマン サービシズ | 膵臓癌を処置するためのペプチドをベースとする方法 |
| WO2017149012A1 (en) * | 2016-03-02 | 2017-09-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Peptides and uses thereof for reducing cd95-mediated cell motility |
| SG11201807770RA (en) * | 2016-03-24 | 2018-10-30 | Nantcell Inc | Sequence arrangements and sequences for neoepitope presentation |
| US12144850B2 (en) | 2016-04-08 | 2024-11-19 | Purdue Research Foundation | Methods and compositions for car T cell therapy |
| EP3454884B1 (en) | 2016-05-10 | 2023-07-12 | Sorbonne Université | Agents that activate cd47 and their use in the treatment of inflammation |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| CN109789190A (zh) | 2016-06-30 | 2019-05-21 | 河谷控股Ip有限责任公司 | Nant癌症疫苗 |
| CN106432014B (zh) * | 2016-09-05 | 2019-08-16 | 中国医学科学院放射医学研究所 | 胺基硫醇类化合物及其制备方法和其在辐射防护中的应用 |
| US10799555B2 (en) | 2016-09-15 | 2020-10-13 | Leidos, Inc. | PD-1 peptide inhibitors |
| TWI808063B (zh) * | 2016-11-09 | 2023-07-11 | 國立臺灣大學 | 治療或預防癌症的方法 |
| US20190358263A1 (en) * | 2016-12-07 | 2019-11-28 | Oslo Universitetssykehus Hf | Compositions and Methods for Cell Therapy |
| CA3051481A1 (en) | 2017-02-07 | 2018-08-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (ple) car t cell tumor targeting (ctct) agents |
| ES3010559T3 (en) | 2017-02-28 | 2025-04-03 | Endocyte Inc | Compositions and methods for car t cell therapy |
| JP2020517259A (ja) | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| AU2018258119B2 (en) | 2017-04-24 | 2021-04-01 | Nantcell, Inc. | Targeted neoepitope vectors and methods therefor |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| ES3041991T3 (en) | 2017-05-25 | 2025-11-17 | Leidos Inc | Pd-1 and ctla-4 dual inhibitor peptides |
| EP3687559B1 (en) | 2017-09-29 | 2025-11-12 | Sanford Burnham Prebys Medical Discovery Institute | Compositions that target tumor-associated macrophages and methods of use therefor |
| CN109745324A (zh) * | 2017-11-06 | 2019-05-14 | 中国科学院上海生命科学研究院 | 非经典NF-kB通路的小分子抑制剂及其应用 |
| JP7549303B2 (ja) | 2018-01-22 | 2024-09-11 | エンドサイト・インコーポレイテッド | Car t細胞の使用方法 |
| CN111936518A (zh) | 2018-02-06 | 2020-11-13 | 西雅图儿童医院(Dba西雅图儿童研究所) | 对fl-ple标记的肿瘤表现出最佳的t细胞功能的荧光素特异性car |
| JP7273421B2 (ja) | 2018-02-21 | 2023-05-15 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用 |
| CN112105382A (zh) | 2018-02-23 | 2020-12-18 | 恩多塞特公司 | 用于car t细胞疗法的顺序方法 |
| AU2018410849B2 (en) | 2018-02-27 | 2025-02-27 | Leidos, Inc. | PD-1 peptide inhibitors |
| US11823773B2 (en) | 2018-04-13 | 2023-11-21 | Nant Holdings Ip, Llc | Nant cancer vaccine strategies |
| EP3810278A1 (en) * | 2018-06-20 | 2021-04-28 | Universidade de Coimbra | (3s)- and (3r)-6,7-bis(hydroxymethyl)-1h,3h-pyrrolo[1,2-c]thiazoles as p53 activators |
| BR112021005464A2 (pt) * | 2018-08-15 | 2021-06-29 | The Regents Of The University Of California | inibição de il-10 para vacinas e imunoterapia |
| US12385903B2 (en) | 2018-08-27 | 2025-08-12 | Nantbio, Inc. | RP182 compositions and methods |
| JP7766489B2 (ja) * | 2018-08-29 | 2025-11-10 | リップタイド バイオサイエンス インコーポレイテッド | 免疫調節特性を有するペプチド |
| US20220143130A1 (en) * | 2018-08-29 | 2022-05-12 | Riptide Bioscience, Inc. | Peptides Having Immunomodulatory Properties |
| US10413584B1 (en) | 2018-08-29 | 2019-09-17 | Riptide Bioscience, Inc. | Peptides having immunomodulatory properties |
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