KR20140062469A - 폴리펩티드 분리 방법 - Google Patents
폴리펩티드 분리 방법 Download PDFInfo
- Publication number
- KR20140062469A KR20140062469A KR1020147004217A KR20147004217A KR20140062469A KR 20140062469 A KR20140062469 A KR 20140062469A KR 1020147004217 A KR1020147004217 A KR 1020147004217A KR 20147004217 A KR20147004217 A KR 20147004217A KR 20140062469 A KR20140062469 A KR 20140062469A
- Authority
- KR
- South Korea
- Prior art keywords
- polypeptide
- medium
- receptor
- gamma
- ser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161509746P | 2011-07-20 | 2011-07-20 | |
| US61/509,746 | 2011-07-20 | ||
| PCT/US2012/047699 WO2013013193A1 (en) | 2011-07-20 | 2012-07-20 | Polypeptide separation methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20140062469A true KR20140062469A (ko) | 2014-05-23 |
Family
ID=46634526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147004217A Ceased KR20140062469A (ko) | 2011-07-20 | 2012-07-20 | 폴리펩티드 분리 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10221210B2 (enExample) |
| EP (1) | EP2734537B1 (enExample) |
| JP (1) | JP2014527518A (enExample) |
| KR (1) | KR20140062469A (enExample) |
| CN (1) | CN103827134A (enExample) |
| AU (1) | AU2012283858C1 (enExample) |
| BR (1) | BR112014001120A2 (enExample) |
| CA (1) | CA2842559A1 (enExample) |
| IL (1) | IL230486A0 (enExample) |
| WO (1) | WO2013013193A1 (enExample) |
| ZA (1) | ZA201401140B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2734537B1 (en) | 2011-07-20 | 2022-12-21 | Zepteon, Incorporated | Polypeptide separation methods |
| JP6356605B2 (ja) * | 2011-10-19 | 2018-07-11 | ロシュ グリクアート アーゲー | フコシル化抗体の分離法 |
| PL2814587T3 (pl) | 2012-02-15 | 2018-10-31 | F.Hoffmann-La Roche Ag | Chromatografia powinowactwa oparta na receptorze Fc |
| ES2834113T3 (es) | 2013-03-15 | 2021-06-16 | H Lundbeck As | Purificación de anticuerpos y monitorización de la pureza |
| EP3048112B1 (en) * | 2013-09-18 | 2020-03-11 | Tosoh Corporation | Fc-BINDING PROTEIN, METHOD FOR PRODUCING SAID PROTEIN, AND ANTIBODY ADSORBENT USING SAID PROTEIN, AND METHODS FOR PURIFYING AND IDENTIFYING ANTIBODY USING SAID ADSORBENT |
| FR3025515B1 (fr) | 2014-09-05 | 2016-09-09 | Lab Francais Du Fractionnement | Procede de purification d'un anticorps monoclonal |
| EP3215528B1 (en) | 2014-11-06 | 2019-08-07 | F.Hoffmann-La Roche Ag | Fc-region variants with modified fcrn-binding and methods of use |
| US20180319838A1 (en) * | 2015-11-04 | 2018-11-08 | Biogen Ma Inc. | Conjugation methods for modifying or immobilizing proteins |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US20200087390A1 (en) | 2016-12-21 | 2020-03-19 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| JP7047425B2 (ja) * | 2017-02-20 | 2022-04-05 | 東ソー株式会社 | 抗体の分離能が向上したFc結合性タンパク質およびそれを用いた抗体の分離方法 |
| EP3702462B1 (en) | 2017-10-27 | 2024-10-09 | Tosoh Corporation | Fc-BINDING PROTEIN EXHIBITING IMPROVED ALKALINE RESISTANCE, METHOD FOR PRODUCING SAID PROTEIN, ANTIBODY ADSORBENT USING SAID PROTEIN, AND METHOD FOR SEPARATING ANTIBODY USING SAID ANTIBODY ADSORBENT |
| CN113272649B (zh) * | 2018-10-25 | 2024-03-12 | 瑞泽恩制药公司 | 用于分析病毒衣壳蛋白组成的方法 |
| JP7700092B2 (ja) * | 2019-07-03 | 2025-06-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | グリコフォームの精製 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932557A (en) | 1972-12-19 | 1976-01-13 | Gulf Research & Development Company | Reactive hydrophilic epoxy containing polymer |
| US4210723A (en) | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
| DE3543348A1 (de) | 1985-12-07 | 1987-06-11 | Bayer Ag | Perlfoermige vernetzte, epoxy- und basische aminogruppen aufweisende mischpolymerisate, verfahren zu ihrer herstellung und ihre verwendung |
| US5260373A (en) | 1987-03-13 | 1993-11-09 | Repligen Corporation | Immobilized immunoglobulin-binding proteins |
| GB8902770D0 (en) | 1989-02-08 | 1989-03-30 | Bioprocessing Ltd | Improvements in or relating to supports for immunoaffinity separations |
| SE467308B (sv) | 1990-10-22 | 1992-06-29 | Berol Nobel Ab | Fast yta belagd med ett hydrofilt ytterskikt med kovalent bundna biopolymerer, saett att framstaella en saadan yta och ett konjugat daerfoer |
| US5456909A (en) * | 1992-08-07 | 1995-10-10 | T Cell Sciences, Inc. | Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo |
| US5543054A (en) | 1993-11-24 | 1996-08-06 | Millipore Corporation | Method and apparatus for covalent immobilization of charge- conjugated carbohydrate molecules |
| SE9503925D0 (sv) | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
| US5874165A (en) | 1996-06-03 | 1999-02-23 | Gore Enterprise Holdings, Inc. | Materials and method for the immobilization of bioactive species onto polymeric subtrates |
| DE69840412D1 (de) * | 1997-10-31 | 2009-02-12 | Genentech Inc | Methoden und zusammensetzungen bestehend aus glykoprotein-glykoformen |
| EP1006183A1 (en) | 1998-12-03 | 2000-06-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Recombinant soluble Fc receptors |
| FR2807767B1 (fr) * | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | Anticorps monoclonaux anti-d |
| US7449308B2 (en) | 2000-06-28 | 2008-11-11 | Glycofi, Inc. | Combinatorial DNA library for producing modified N-glycans in lower eukaryotes |
| US7598055B2 (en) | 2000-06-28 | 2009-10-06 | Glycofi, Inc. | N-acetylglucosaminyltransferase III expression in lower eukaryotes |
| ATE440959T1 (de) | 2000-06-28 | 2009-09-15 | Glycofi Inc | Verfahren für die herstellung modifizierter glykoproteine |
| US7625756B2 (en) | 2000-06-28 | 2009-12-01 | GycoFi, Inc. | Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells |
| WO2002030954A1 (en) * | 2000-10-06 | 2002-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Method of purifying antibody |
| KR100988949B1 (ko) | 2001-10-25 | 2010-10-20 | 제넨테크, 인크. | 당단백질 조성물 |
| ITMI20020729A1 (it) | 2002-04-08 | 2003-10-08 | Resindion S R L | Supporti per l'immobilizzazione covalente di enzimi |
| US7261893B2 (en) | 2002-10-22 | 2007-08-28 | Wyeth | Neutralizing antibodies against GDF-8 and uses therefor |
| ES2214136B1 (es) | 2003-02-21 | 2007-05-16 | Consejo Sup. De Invest. Cientificas. | Nuevo metodo de inmovilizacion de enzimas y otras bio-macromoleculas sobre soportes activados con grupos epoxido conteniendo grupos ionizados en el brazo espaciador que une cada grupo epoxido a la superficie del soporte. |
| EP1737969B2 (en) | 2004-04-15 | 2018-09-12 | GlycoFi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| JP4839583B2 (ja) | 2004-07-15 | 2011-12-21 | 和光純薬工業株式会社 | FcγレセプターIIIaに特異的な抗体およびそれを用いたFcγレセプターIIIaの測定方法 |
| AU2005279347A1 (en) * | 2004-08-30 | 2006-03-09 | Lonza Biologics Plc. | Affinity- plus ion exchange- chromatography for purifying antibodies |
| ES2396555T3 (es) | 2004-12-15 | 2013-02-22 | Janssen Alzheimer Immunotherapy | Anticuerpos que reconocen péptido beta amiloide |
| DK1869065T3 (da) | 2005-03-11 | 2020-06-08 | Wyeth Llc | Fremgangsmåde til kromatografi med svag opdeling |
| BRPI0611600B8 (pt) * | 2005-06-17 | 2021-05-25 | Wyeth Corp | método para purificação de uma proteína tendo uma região fc a partir de um líquido fonte compreendendo a proteína e uma ou mais impurezas, e kit |
| ES2417147T3 (es) | 2005-10-21 | 2013-08-06 | Revo Biologics, Inc. | Anticuerpos con actividad de citotoxicidad celular dependiente de anticuerpos mejorada, métodos para su producción y uso |
| CN101365948B (zh) * | 2006-01-06 | 2012-11-07 | Emd密理博公司 | 亲和层析基质及其制备和使用方法 |
| KR101495549B1 (ko) | 2006-07-13 | 2015-02-25 | 와이어쓰 엘엘씨 | 당단백질의 생산 |
| US8969532B2 (en) | 2006-10-03 | 2015-03-03 | Novo Nordisk A/S | Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography |
| WO2008085988A1 (en) * | 2007-01-05 | 2008-07-17 | Amgen Inc. | Methods of purifying proteins |
| US20080248510A1 (en) | 2007-04-03 | 2008-10-09 | Ulrich Brinkmann | HUMAN Fc GAMMA RECEPTOR III |
| AU2008240078B2 (en) | 2007-04-16 | 2012-10-25 | Momenta Pharmaceuticals, Inc. | Multi-dimensional chromatographic methods for separating N-glycans |
| US7919313B2 (en) | 2007-07-12 | 2011-04-05 | Sangamo Biosciences, Inc. | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression |
| US20090035807A1 (en) * | 2007-07-31 | 2009-02-05 | Wyeth | Analysis of polypeptide production |
| CA2697091A1 (en) * | 2007-08-31 | 2009-03-05 | F. Hoffmann-La Roche Ag | Glycosylation profile analysis |
| EP2365979A2 (en) * | 2008-10-22 | 2011-09-21 | Biogen Idec MA Inc. | Recombinant fcrn and variants thereof for purification of fc-containing fusion proteins |
| JP2010126436A (ja) * | 2008-11-25 | 2010-06-10 | Tosoh Corp | 抗体精製用吸着剤、およびそれを用いた抗体精製方法 |
| ES2817802T3 (es) * | 2009-08-07 | 2021-04-08 | Emd Millipore Corp | Métodos para purificar una proteína objetivo de una o más impurezas en una muestra |
| EP2734537B1 (en) | 2011-07-20 | 2022-12-21 | Zepteon, Incorporated | Polypeptide separation methods |
| JP6356605B2 (ja) | 2011-10-19 | 2018-07-11 | ロシュ グリクアート アーゲー | フコシル化抗体の分離法 |
-
2012
- 2012-07-20 EP EP12743825.7A patent/EP2734537B1/en not_active Revoked
- 2012-07-20 BR BR112014001120A patent/BR112014001120A2/pt not_active IP Right Cessation
- 2012-07-20 WO PCT/US2012/047699 patent/WO2013013193A1/en not_active Ceased
- 2012-07-20 CN CN201280045699.2A patent/CN103827134A/zh active Pending
- 2012-07-20 KR KR1020147004217A patent/KR20140062469A/ko not_active Ceased
- 2012-07-20 AU AU2012283858A patent/AU2012283858C1/en not_active Ceased
- 2012-07-20 JP JP2014521843A patent/JP2014527518A/ja active Pending
- 2012-07-20 CA CA2842559A patent/CA2842559A1/en not_active Abandoned
- 2012-07-20 US US13/554,501 patent/US10221210B2/en active Active
-
2014
- 2014-01-16 IL IL230486A patent/IL230486A0/en unknown
- 2014-02-14 ZA ZA2014/01140A patent/ZA201401140B/en unknown
-
2019
- 2019-01-08 US US16/242,113 patent/US20190194248A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130084648A1 (en) | 2013-04-04 |
| US20190194248A1 (en) | 2019-06-27 |
| BR112014001120A2 (pt) | 2017-02-21 |
| WO2013013193A1 (en) | 2013-01-24 |
| ZA201401140B (en) | 2015-04-29 |
| JP2014527518A (ja) | 2014-10-16 |
| US10221210B2 (en) | 2019-03-05 |
| CA2842559A1 (en) | 2013-01-24 |
| AU2012283858B2 (en) | 2017-07-06 |
| IL230486A0 (en) | 2014-03-31 |
| EP2734537A1 (en) | 2014-05-28 |
| AU2012283858C1 (en) | 2020-01-23 |
| AU2012283858A1 (en) | 2014-03-06 |
| EP2734537B1 (en) | 2022-12-21 |
| CN103827134A (zh) | 2014-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20140219 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20170719 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20180627 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20180918 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20180627 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |