IL230486A0 - Methods for the separation of polypeptides - Google Patents

Methods for the separation of polypeptides

Info

Publication number
IL230486A0
IL230486A0 IL230486A IL23048614A IL230486A0 IL 230486 A0 IL230486 A0 IL 230486A0 IL 230486 A IL230486 A IL 230486A IL 23048614 A IL23048614 A IL 23048614A IL 230486 A0 IL230486 A0 IL 230486A0
Authority
IL
Israel
Prior art keywords
separation methods
polypeptide separation
polypeptide
methods
separation
Prior art date
Application number
IL230486A
Other languages
English (en)
Hebrew (he)
Original Assignee
Zepteon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46634526&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL230486(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zepteon Inc filed Critical Zepteon Inc
Publication of IL230486A0 publication Critical patent/IL230486A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL230486A 2011-07-20 2014-01-16 Methods for the separation of polypeptides IL230486A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161509746P 2011-07-20 2011-07-20
PCT/US2012/047699 WO2013013193A1 (en) 2011-07-20 2012-07-20 Polypeptide separation methods

Publications (1)

Publication Number Publication Date
IL230486A0 true IL230486A0 (en) 2014-03-31

Family

ID=46634526

Family Applications (1)

Application Number Title Priority Date Filing Date
IL230486A IL230486A0 (en) 2011-07-20 2014-01-16 Methods for the separation of polypeptides

Country Status (11)

Country Link
US (2) US10221210B2 (enExample)
EP (1) EP2734537B1 (enExample)
JP (1) JP2014527518A (enExample)
KR (1) KR20140062469A (enExample)
CN (1) CN103827134A (enExample)
AU (1) AU2012283858C1 (enExample)
BR (1) BR112014001120A2 (enExample)
CA (1) CA2842559A1 (enExample)
IL (1) IL230486A0 (enExample)
WO (1) WO2013013193A1 (enExample)
ZA (1) ZA201401140B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2734537B1 (en) 2011-07-20 2022-12-21 Zepteon, Incorporated Polypeptide separation methods
JP6356605B2 (ja) * 2011-10-19 2018-07-11 ロシュ グリクアート アーゲー フコシル化抗体の分離法
PL2814587T3 (pl) 2012-02-15 2018-10-31 F.Hoffmann-La Roche Ag Chromatografia powinowactwa oparta na receptorze Fc
ES2834113T3 (es) 2013-03-15 2021-06-16 H Lundbeck As Purificación de anticuerpos y monitorización de la pureza
EP3048112B1 (en) * 2013-09-18 2020-03-11 Tosoh Corporation Fc-BINDING PROTEIN, METHOD FOR PRODUCING SAID PROTEIN, AND ANTIBODY ADSORBENT USING SAID PROTEIN, AND METHODS FOR PURIFYING AND IDENTIFYING ANTIBODY USING SAID ADSORBENT
FR3025515B1 (fr) 2014-09-05 2016-09-09 Lab Francais Du Fractionnement Procede de purification d'un anticorps monoclonal
EP3215528B1 (en) 2014-11-06 2019-08-07 F.Hoffmann-La Roche Ag Fc-region variants with modified fcrn-binding and methods of use
US20180319838A1 (en) * 2015-11-04 2018-11-08 Biogen Ma Inc. Conjugation methods for modifying or immobilizing proteins
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
US20200087390A1 (en) 2016-12-21 2020-03-19 Amgen Inc. Anti-tnf alpha antibody formulations
JP7047425B2 (ja) * 2017-02-20 2022-04-05 東ソー株式会社 抗体の分離能が向上したＦｃ結合性タンパク質およびそれを用いた抗体の分離方法
EP3702462B1 (en) 2017-10-27 2024-10-09 Tosoh Corporation Fc-BINDING PROTEIN EXHIBITING IMPROVED ALKALINE RESISTANCE, METHOD FOR PRODUCING SAID PROTEIN, ANTIBODY ADSORBENT USING SAID PROTEIN, AND METHOD FOR SEPARATING ANTIBODY USING SAID ANTIBODY ADSORBENT
CN113272649B (zh) * 2018-10-25 2024-03-12 瑞泽恩制药公司 用于分析病毒衣壳蛋白组成的方法
JP7700092B2 (ja) * 2019-07-03 2025-06-30 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング グリコフォームの精製

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932557A (en) 1972-12-19 1976-01-13 Gulf Research & Development Company Reactive hydrophilic epoxy containing polymer
US4210723A (en) 1976-07-23 1980-07-01 The Dow Chemical Company Method of coupling a protein to an epoxylated latex
DE3543348A1 (de) 1985-12-07 1987-06-11 Bayer Ag Perlfoermige vernetzte, epoxy- und basische aminogruppen aufweisende mischpolymerisate, verfahren zu ihrer herstellung und ihre verwendung
US5260373A (en) 1987-03-13 1993-11-09 Repligen Corporation Immobilized immunoglobulin-binding proteins
GB8902770D0 (en) 1989-02-08 1989-03-30 Bioprocessing Ltd Improvements in or relating to supports for immunoaffinity separations
SE467308B (sv) 1990-10-22 1992-06-29 Berol Nobel Ab Fast yta belagd med ett hydrofilt ytterskikt med kovalent bundna biopolymerer, saett att framstaella en saadan yta och ett konjugat daerfoer
US5456909A (en) * 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
US5543054A (en) 1993-11-24 1996-08-06 Millipore Corporation Method and apparatus for covalent immobilization of charge- conjugated carbohydrate molecules
SE9503925D0 (sv) 1995-11-07 1995-11-07 Pharmacia Biotech Ab Separationsmedium för IgG
US5874165A (en) 1996-06-03 1999-02-23 Gore Enterprise Holdings, Inc. Materials and method for the immobilization of bioactive species onto polymeric subtrates
DE69840412D1 (de) * 1997-10-31 2009-02-12 Genentech Inc Methoden und zusammensetzungen bestehend aus glykoprotein-glykoformen
EP1006183A1 (en) 1998-12-03 2000-06-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Recombinant soluble Fc receptors
FR2807767B1 (fr) * 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7598055B2 (en) 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
ATE440959T1 (de) 2000-06-28 2009-09-15 Glycofi Inc Verfahren für die herstellung modifizierter glykoproteine
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
WO2002030954A1 (en) * 2000-10-06 2002-04-18 Kyowa Hakko Kogyo Co., Ltd. Method of purifying antibody
KR100988949B1 (ko) 2001-10-25 2010-10-20 제넨테크, 인크. 당단백질 조성물
ITMI20020729A1 (it) 2002-04-08 2003-10-08 Resindion S R L Supporti per l'immobilizzazione covalente di enzimi
US7261893B2 (en) 2002-10-22 2007-08-28 Wyeth Neutralizing antibodies against GDF-8 and uses therefor
ES2214136B1 (es) 2003-02-21 2007-05-16 Consejo Sup. De Invest. Cientificas. Nuevo metodo de inmovilizacion de enzimas y otras bio-macromoleculas sobre soportes activados con grupos epoxido conteniendo grupos ionizados en el brazo espaciador que une cada grupo epoxido a la superficie del soporte.
EP1737969B2 (en) 2004-04-15 2018-09-12 GlycoFi, Inc. Production of galactosylated glycoproteins in lower eukaryotes
JP4839583B2 (ja) 2004-07-15 2011-12-21 和光純薬工業株式会社 ＦｃγレセプターＩＩＩａに特異的な抗体およびそれを用いたＦｃγレセプターＩＩＩａの測定方法
AU2005279347A1 (en) * 2004-08-30 2006-03-09 Lonza Biologics Plc. Affinity- plus ion exchange- chromatography for purifying antibodies
ES2396555T3 (es) 2004-12-15 2013-02-22 Janssen Alzheimer Immunotherapy Anticuerpos que reconocen péptido beta amiloide
DK1869065T3 (da) 2005-03-11 2020-06-08 Wyeth Llc Fremgangsmåde til kromatografi med svag opdeling
BRPI0611600B8 (pt) * 2005-06-17 2021-05-25 Wyeth Corp método para purificação de uma proteína tendo uma região fc a partir de um líquido fonte compreendendo a proteína e uma ou mais impurezas, e kit
ES2417147T3 (es) 2005-10-21 2013-08-06 Revo Biologics, Inc. Anticuerpos con actividad de citotoxicidad celular dependiente de anticuerpos mejorada, métodos para su producción y uso
CN101365948B (zh) * 2006-01-06 2012-11-07 Emd密理博公司 亲和层析基质及其制备和使用方法
KR101495549B1 (ko) 2006-07-13 2015-02-25 와이어쓰 엘엘씨 당단백질의 생산
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
WO2008085988A1 (en) * 2007-01-05 2008-07-17 Amgen Inc. Methods of purifying proteins
US20080248510A1 (en) 2007-04-03 2008-10-09 Ulrich Brinkmann HUMAN Fc GAMMA RECEPTOR III
AU2008240078B2 (en) 2007-04-16 2012-10-25 Momenta Pharmaceuticals, Inc. Multi-dimensional chromatographic methods for separating N-glycans
US7919313B2 (en) 2007-07-12 2011-04-05 Sangamo Biosciences, Inc. Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
US20090035807A1 (en) * 2007-07-31 2009-02-05 Wyeth Analysis of polypeptide production
CA2697091A1 (en) * 2007-08-31 2009-03-05 F. Hoffmann-La Roche Ag Glycosylation profile analysis
EP2365979A2 (en) * 2008-10-22 2011-09-21 Biogen Idec MA Inc. Recombinant fcrn and variants thereof for purification of fc-containing fusion proteins
JP2010126436A (ja) * 2008-11-25 2010-06-10 Tosoh Corp 抗体精製用吸着剤、およびそれを用いた抗体精製方法
ES2817802T3 (es) * 2009-08-07 2021-04-08 Emd Millipore Corp Métodos para purificar una proteína objetivo de una o más impurezas en una muestra
EP2734537B1 (en) 2011-07-20 2022-12-21 Zepteon, Incorporated Polypeptide separation methods
JP6356605B2 (ja) 2011-10-19 2018-07-11 ロシュ グリクアート アーゲー フコシル化抗体の分離法

Also Published As

Publication number Publication date
US20130084648A1 (en) 2013-04-04
US20190194248A1 (en) 2019-06-27
BR112014001120A2 (pt) 2017-02-21
WO2013013193A1 (en) 2013-01-24
KR20140062469A (ko) 2014-05-23
ZA201401140B (en) 2015-04-29
JP2014527518A (ja) 2014-10-16
US10221210B2 (en) 2019-03-05
CA2842559A1 (en) 2013-01-24
AU2012283858B2 (en) 2017-07-06
EP2734537A1 (en) 2014-05-28
AU2012283858C1 (en) 2020-01-23
AU2012283858A1 (en) 2014-03-06
EP2734537B1 (en) 2022-12-21
CN103827134A (zh) 2014-05-28

Similar Documents

Publication Publication Date Title
GB2522810B (en) Separating apparatus
IL232193A0 (en) membranes for separation
ZA201401140B (en) Polypeptide separation methods
ZA201309174B (en) Polypeptides
SG11201400432VA (en) Polypeptide vaccine
ZA201207920B (en) Separation method
GB201113811D0 (en) Protein recovery
GB2487195B (en) Separation device
GB201111183D0 (en) Peptide
SG10201606218WA (en) Purified Proteins
PL2665806T3 (pl) Urządzenie rozdzielające
GB201115910D0 (en) Peptides
ZA201400119B (en) Separation process
ZA201209070B (en) Separation method
GB201005991D0 (en) Separation method
PL2663388T3 (pl) System separacji elektromembranowej
GB201112849D0 (en) Polypeptide
GB201106130D0 (en) Polypeptide
GB201112985D0 (en) Polypeptide
GB2510702B (en) Separator
GB201115014D0 (en) Peptides
ZA201201634B (en) Material separation
GB201112296D0 (en) Separation process
GB201112297D0 (en) Separation process
GB201103967D0 (en) Polypeptide detection