KR20120113709A - 벤조이미다졸 화합물 및 그의 용도 - Google Patents
벤조이미다졸 화합물 및 그의 용도 Download PDFInfo
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- KR20120113709A KR20120113709A KR1020127012726A KR20127012726A KR20120113709A KR 20120113709 A KR20120113709 A KR 20120113709A KR 1020127012726 A KR1020127012726 A KR 1020127012726A KR 20127012726 A KR20127012726 A KR 20127012726A KR 20120113709 A KR20120113709 A KR 20120113709A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26226309P | 2009-11-18 | 2009-11-18 | |
| US61/262,263 | 2009-11-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20120113709A true KR20120113709A (ko) | 2012-10-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127012726A Withdrawn KR20120113709A (ko) | 2009-11-18 | 2010-11-17 | 벤조이미다졸 화합물 및 그의 용도 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8530467B2 (enExample) |
| EP (1) | EP2501697B1 (enExample) |
| JP (1) | JP5657018B2 (enExample) |
| KR (1) | KR20120113709A (enExample) |
| CN (1) | CN102741245B (enExample) |
| AR (1) | AR079050A1 (enExample) |
| AU (1) | AU2010322478B2 (enExample) |
| BR (1) | BR112012011518B8 (enExample) |
| CA (1) | CA2777746C (enExample) |
| ES (1) | ES2442797T3 (enExample) |
| IN (1) | IN2012DN03391A (enExample) |
| MX (1) | MX2012005329A (enExample) |
| RU (1) | RU2542582C2 (enExample) |
| TW (1) | TW201121957A (enExample) |
| UY (1) | UY33037A (enExample) |
| WO (1) | WO2011062550A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150123812A (ko) * | 2013-01-31 | 2015-11-04 | 네오메드 인스티튜트 | 이미다조피리딘 화합물 및 이의 용도 |
| KR20200092938A (ko) * | 2017-09-18 | 2020-08-04 | 벨루스 헬스 코프 인크. | 선택적 p2x3 조정제 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012158117A1 (en) * | 2011-05-17 | 2012-11-22 | Astrazeneca Ab | Combination therapies for treating pain |
| WO2015093586A1 (ja) * | 2013-12-20 | 2015-06-25 | 塩野義製薬株式会社 | トロンボポエチン受容体アゴニスト作用を有する光学活性な化合物およびその中間体の製造方法 |
| WO2016004358A1 (en) | 2014-07-03 | 2016-01-07 | Afferent Pharmaceuticals, Inc. | Methods and compositions for treating diseases and conditions |
| CN108904507A (zh) * | 2018-02-11 | 2018-11-30 | 赖英杰 | P2x3受体调节剂苯并咪唑化合物在制备抗呼吸疾病药物中的应用 |
| KR102797127B1 (ko) * | 2018-12-29 | 2025-04-21 | 우한 크리에이터나 사이언스 앤드 테크놀로지 컴퍼니, 리미티드 | 헤테로고리계 화합물, 중간체, 이의 제조 방법 및 용도 |
| CN113727716A (zh) * | 2019-02-25 | 2021-11-30 | 贝卢斯医疗咳嗽病公司 | 采用p2x3调节剂的治疗 |
| BR112022015858A2 (pt) * | 2020-02-14 | 2022-10-25 | Bellus Health Cough Inc | Composto, composição farmacêutica, e, métodos para tratar um distúrbio associado à atividade de p2x3, para tratar dor, para tratar um distúrbio do trato urinário, para reduzir ou prevenir a perda descontrolada de urina, para tratar tosse, para tratar prurido e para tratar endometriose, dor associada à endometriose e sintomas associados à endometriose |
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| TW202227458A (zh) * | 2020-12-04 | 2022-07-16 | 大陸商上海拓界生物醫藥科技有限公司 | 含有稠合三環的化合物及其醫藥用途 |
| CN114478508A (zh) * | 2021-12-31 | 2022-05-13 | 淮北师范大学 | 一种苯并咪唑化合物的结晶形式 |
| TW202342468A (zh) * | 2022-02-11 | 2023-11-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | P2x3受體拮抗劑的晶型及其製備方法 |
| TW202337452A (zh) * | 2022-02-11 | 2023-10-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | P2x3受體拮抗劑的藥用鹽及其製備方法 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150123812A (ko) * | 2013-01-31 | 2015-11-04 | 네오메드 인스티튜트 | 이미다조피리딘 화합물 및 이의 용도 |
| KR20200092938A (ko) * | 2017-09-18 | 2020-08-04 | 벨루스 헬스 코프 인크. | 선택적 p2x3 조정제 |
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| ES2442797T3 (es) | 2014-02-13 |
| TW201121957A (en) | 2011-07-01 |
| MX2012005329A (es) | 2012-05-29 |
| CA2777746C (en) | 2019-05-14 |
| AU2010322478A1 (en) | 2012-05-31 |
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| CN102741245A (zh) | 2012-10-17 |
| JP5657018B2 (ja) | 2015-01-21 |
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| BR112012011518A2 (pt) | 2016-06-28 |
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| JP2013511517A (ja) | 2013-04-04 |
| CN102741245B (zh) | 2014-11-05 |
| EP2501697A1 (en) | 2012-09-26 |
| IN2012DN03391A (enExample) | 2015-10-23 |
| RU2542582C2 (ru) | 2015-02-20 |
| US20120289504A1 (en) | 2012-11-15 |
| EP2501697B1 (en) | 2013-10-23 |
| RU2012124268A (ru) | 2013-12-27 |
| BR112012011518B8 (pt) | 2023-01-10 |
| AU2010322478B2 (en) | 2013-11-14 |
| WO2011062550A1 (en) | 2011-05-26 |
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