KR20120049900A - 항원성 타우 펩타이드 및 이의 용도 - Google Patents
항원성 타우 펩타이드 및 이의 용도 Download PDFInfo
- Publication number
- KR20120049900A KR20120049900A KR1020127005415A KR20127005415A KR20120049900A KR 20120049900 A KR20120049900 A KR 20120049900A KR 1020127005415 A KR1020127005415 A KR 1020127005415A KR 20127005415 A KR20127005415 A KR 20127005415A KR 20120049900 A KR20120049900 A KR 20120049900A
- Authority
- KR
- South Korea
- Prior art keywords
- peptide
- tau
- antigenic
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 | |
| US61/229,860 | 2009-07-30 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137028550A Division KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20120049900A true KR20120049900A (ko) | 2012-05-17 |
Family
ID=42941871
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127005415A Abandoned KR20120049900A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
| KR1020137028550A Ceased KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020137028550A Ceased KR20130127547A (ko) | 2009-07-30 | 2010-07-20 | 항원성 타우 펩타이드 및 이의 용도 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110177109A1 (enExample) |
| EP (1) | EP2459214A1 (enExample) |
| JP (1) | JP2013500326A (enExample) |
| KR (2) | KR20120049900A (enExample) |
| CN (1) | CN102596236B (enExample) |
| AR (1) | AR078085A1 (enExample) |
| AU (1) | AU2010277254B2 (enExample) |
| CA (1) | CA2768346A1 (enExample) |
| CO (1) | CO6612199A2 (enExample) |
| IN (1) | IN2012DN00446A (enExample) |
| MX (1) | MX2012001194A (enExample) |
| NZ (2) | NZ618391A (enExample) |
| PE (1) | PE20120817A1 (enExample) |
| RU (2) | RU2518291C2 (enExample) |
| SG (1) | SG177637A1 (enExample) |
| TW (2) | TW201436804A (enExample) |
| WO (1) | WO2011013034A1 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010067262A1 (en) | 2008-12-09 | 2010-06-17 | Pfizer Inc. | Immunostimulatory oligonucleotides |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| CA3239368A1 (en) * | 2009-06-10 | 2010-12-16 | New York University | Immunological targeting of pathological tau proteins |
| PE20140218A1 (es) * | 2010-10-07 | 2014-03-01 | Ac Inmune S A | Composicion farmaceutica |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| US8703137B2 (en) | 2011-01-31 | 2014-04-22 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| CA2841577C (en) | 2011-07-11 | 2018-12-04 | Indi Molecular, Inc. | Akt-specific capture agents, compositions, and methods of using and making |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| ES2600915T3 (es) | 2011-10-07 | 2017-02-13 | Ac Immune S.A. | Anticuerpos fosfoespecíficos que reconocen Tau |
| EP2834270B1 (en) | 2012-04-05 | 2019-10-30 | AC Immune S.A. | Humanized tau antibody |
| JP6345655B2 (ja) * | 2012-07-03 | 2018-06-20 | ワシントン・ユニバーシティWashington University | タウに対する抗体 |
| DK2885010T3 (da) | 2012-08-16 | 2020-02-03 | Ipierian Inc | Fremgangsmåder til behandling med tauopati |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| BR112015023262B8 (pt) | 2013-03-15 | 2024-02-06 | Ac Immune Sa | Anticorpo isolado, imunoconjugado, formulação farmacêutica e usos do anticorpo |
| US10195257B2 (en) * | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン,インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| JP6913018B2 (ja) | 2014-07-08 | 2021-08-04 | ニューヨーク・ユニバーシティ | タウイメージングリガンド、ならびにタウ異常症の診断および治療におけるそれらの使用 |
| WO2016154522A1 (en) * | 2015-03-25 | 2016-09-29 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
| MX2017015908A (es) | 2015-07-06 | 2018-03-15 | Ucb Biopharma Sprl | Anticuerpos de union a tau. |
| CN115112898B (zh) | 2015-07-15 | 2026-03-24 | 加州理工学院 | Il-17f-特异性捕获剂、组合物以及使用和制造的方法 |
| CN108135986B (zh) | 2015-08-13 | 2022-07-29 | 纽约大学 | 对于Tau的截短的Asp421表位特异性的基于抗体的分子和它们在诊断和治疗Tau疾病中的用途 |
| EP3440101B1 (en) | 2016-04-04 | 2021-10-06 | Indi Molecular, Inc. | Cd8-specific capture agents, compositions, and methods of using and making |
| US11884707B2 (en) | 2016-09-29 | 2024-01-30 | Regeneron Pharmaceuticals, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| US11719705B2 (en) | 2017-06-15 | 2023-08-08 | Indi Molecular, Inc. | IL-17F and IL-17A-specific capture agents, compositions, and methods of using and making |
| EA202091012A1 (ru) | 2017-10-25 | 2020-08-27 | Янссен Фармасьютикалз, Инк. | Композиции фосфорилированных тау-пептидов и их применения |
| AU2018355574B2 (en) | 2017-10-27 | 2025-09-04 | United Neuroscience | Tau peptide immunogen constructs |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
| GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
| EP3861015A4 (en) * | 2018-10-07 | 2022-11-23 | The University of British Columbia | CONFORMATION SPECIFIC EPITOPES IN ALPHA-SYNUCLEIN, ANTIBODIES DIRECTED AGAINST AND METHODS THEREOF |
| CN113597431B (zh) * | 2019-02-08 | 2025-02-21 | 普罗塞纳生物科学有限公司 | 识别Tau的抗体 |
| CN113710269A (zh) | 2019-02-08 | 2021-11-26 | Ac免疫有限公司 | 磷酸化Tau肽疫苗的安全施用方法 |
| WO2020186091A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| CA3135170A1 (en) | 2019-04-05 | 2020-10-08 | Tauc3 Biologics Limited | Anti-tauc3 antibodies and uses thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| MA55902A (fr) | 2019-04-24 | 2022-03-16 | Ac Immune Sa | Administration hétérologue de vaccins tau |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| AU2020284288A1 (en) * | 2019-05-27 | 2022-01-20 | Promis Neurosciences Inc. | Conformation-specific epitopes in tau, antibodies thereto and methods related thereof |
| GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| CN117751132A (zh) * | 2020-08-07 | 2024-03-22 | 普罗塞纳生物科学有限公司 | 用于治疗阿尔兹海默氏病的tau疫苗 |
| WO2022054795A1 (ja) * | 2020-09-08 | 2022-03-17 | 国立大学法人大阪大学 | リン酸化タウタンパク質を標的とする免疫原性組成物 |
| KR20240052854A (ko) * | 2021-09-08 | 2024-04-23 | 조인트 스탁 컴퍼니 "바이오케드" | Mhc 단백질 기반 이종 이량체를 포함하는 이중 특이적 항체 |
| WO2023056369A1 (en) * | 2021-09-29 | 2023-04-06 | Janssen Pharmaceuticals, Inc. | Method of safe administration of tau phosphopeptide conjugate |
| CN115894659B (zh) * | 2022-10-19 | 2023-11-10 | 上海优宁维生物科技股份有限公司 | 微管相关蛋白Tau抗原及其制备方法和应用 |
| WO2025227011A1 (en) * | 2024-04-26 | 2025-10-30 | Unm Rainforest Innovations | Immunotherapy compositions and methods for treatment of tauopathy, neuroinflammation, and synaptic loss |
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2010
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en not_active Ceased
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
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2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102596236B (zh) | 2015-06-24 |
| NZ618391A (en) | 2015-07-31 |
| WO2011013034A1 (en) | 2011-02-03 |
| TW201436804A (zh) | 2014-10-01 |
| RU2518291C2 (ru) | 2014-06-10 |
| TW201106968A (en) | 2011-03-01 |
| EP2459214A1 (en) | 2012-06-06 |
| NZ598356A (en) | 2014-06-27 |
| CN102596236A (zh) | 2012-07-18 |
| TWI461209B (zh) | 2014-11-21 |
| US20110177109A1 (en) | 2011-07-21 |
| WO2011013034A4 (en) | 2011-04-28 |
| AU2010277254B2 (en) | 2015-05-07 |
| AR078085A1 (es) | 2011-10-12 |
| KR20130127547A (ko) | 2013-11-22 |
| PE20120817A1 (es) | 2012-07-07 |
| MX2012001194A (es) | 2012-03-07 |
| AU2010277254A1 (en) | 2012-02-09 |
| RU2014112002A (ru) | 2015-10-10 |
| RU2012102701A (ru) | 2013-09-10 |
| CA2768346A1 (en) | 2011-02-03 |
| SG177637A1 (en) | 2012-03-29 |
| CO6612199A2 (es) | 2013-02-01 |
| JP2013500326A (ja) | 2013-01-07 |
| IN2012DN00446A (enExample) | 2015-05-15 |
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