IN2012DN00446A - - Google Patents
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- Publication number
- IN2012DN00446A IN2012DN00446A IN446DEN2012A IN2012DN00446A IN 2012DN00446 A IN2012DN00446 A IN 2012DN00446A IN 446DEN2012 A IN446DEN2012 A IN 446DEN2012A IN 2012DN00446 A IN2012DN00446 A IN 2012DN00446A
- Authority
- IN
- India
- Prior art keywords
- immunogens
- compositions
- tau
- medicine
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 | |
| PCT/IB2010/053313 WO2011013034A1 (en) | 2009-07-30 | 2010-07-20 | Antigenic tau peptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN00446A true IN2012DN00446A (enExample) | 2015-05-15 |
Family
ID=42941871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN446DEN2012 IN2012DN00446A (enExample) | 2009-07-30 | 2010-07-20 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110177109A1 (enExample) |
| EP (1) | EP2459214A1 (enExample) |
| JP (1) | JP2013500326A (enExample) |
| KR (2) | KR20120049900A (enExample) |
| CN (1) | CN102596236B (enExample) |
| AR (1) | AR078085A1 (enExample) |
| AU (1) | AU2010277254B2 (enExample) |
| CA (1) | CA2768346A1 (enExample) |
| CO (1) | CO6612199A2 (enExample) |
| IN (1) | IN2012DN00446A (enExample) |
| MX (1) | MX2012001194A (enExample) |
| NZ (2) | NZ598356A (enExample) |
| PE (1) | PE20120817A1 (enExample) |
| RU (2) | RU2518291C2 (enExample) |
| SG (1) | SG177637A1 (enExample) |
| TW (2) | TWI461209B (enExample) |
| WO (1) | WO2011013034A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010067262A1 (en) | 2008-12-09 | 2010-06-17 | Pfizer Inc. | Immunostimulatory oligonucleotides |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| EP3329932A1 (en) | 2009-06-10 | 2018-06-06 | New York University | Immunological targeting of pathological tau proteins |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| KR101988672B1 (ko) * | 2010-10-07 | 2019-06-12 | 에이씨 이뮨 에스.에이. | 타우를 인식하는 포스포특이적 항체 |
| US20120244174A1 (en) | 2011-01-31 | 2012-09-27 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| US9239332B2 (en) | 2011-07-11 | 2016-01-19 | Indi Molecular, Inc. | Akt-specific capture agents, compositions, and methods of using and making |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| AR092779A1 (es) | 2011-10-07 | 2015-05-06 | Ac Immune Sa | Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau |
| JP6293731B2 (ja) | 2012-04-05 | 2018-03-14 | エーシー イミューン エス.エー. | ヒト化タウ抗体 |
| KR20150036346A (ko) * | 2012-07-03 | 2015-04-07 | 워싱턴 유니버시티 | Tau에 대한 항체 |
| RS60080B1 (sr) | 2012-08-16 | 2020-05-29 | Ipierian Inc | Metodi lečenja tauopatije |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| RU2661111C2 (ru) | 2013-03-15 | 2018-07-11 | Ац Иммуне С.А. | Антитела к тау и способы применения |
| EP3027205A4 (en) * | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン,インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| ES2985805T3 (es) | 2014-07-08 | 2024-11-07 | Univ New York | Ligandos de formación de imágenes de TAU y sus usos en el diagnóstico y el tratamiento de tauopatías |
| US20180050097A1 (en) * | 2015-03-25 | 2018-02-22 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
| KR102742965B1 (ko) | 2015-07-06 | 2024-12-13 | 유씨비 바이오파마 에스알엘 | 타우 결합 항체 |
| ES3017796T3 (en) | 2015-07-15 | 2025-05-13 | California Inst Of Techn | Il-17f-specific capture agents and methods of using |
| JP6913078B2 (ja) | 2015-08-13 | 2021-08-04 | ニューヨーク・ユニバーシティ | タウの短縮型Asp421エピトープに特異的な、抗体を基にした分子、ならびにタウ異常症の診断および治療におけるそれらの使用 |
| US11884707B2 (en) | 2016-09-29 | 2024-01-30 | Regeneron Pharmaceuticals, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| AU2018355325B2 (en) * | 2017-10-25 | 2024-11-28 | Ac Immune S.A. | Compositions of phosphorylated tau peptides and uses thereof |
| US11773148B2 (en) * | 2017-10-27 | 2023-10-03 | United Neuroscience | Tau peptide immunogen constructs |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
| GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
| CA3148562A1 (en) * | 2018-10-07 | 2020-04-16 | Neil R. Cashman | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
| US11684576B2 (en) | 2019-02-08 | 2023-06-27 | Ac Immune Sa | Method of safe administration of phosphorylated tau peptide vaccine |
| MX2021009440A (es) * | 2019-02-08 | 2021-09-10 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau. |
| WO2020186091A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| JP7748876B2 (ja) | 2019-04-05 | 2025-10-03 | タウク3 バイオロジクス リミテッド | 抗タウc3抗体及びその使用 |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| JP7617852B2 (ja) | 2019-04-24 | 2025-01-20 | ヤンセン ファーマシューティカルズ,インコーポレーテッド | タウワクチンの異種投与 |
| US12216122B2 (en) | 2019-05-20 | 2025-02-04 | Regeneron Pharmaceuticals, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1) |
| CA3142040A1 (en) * | 2019-05-27 | 2020-12-03 | The University Of British Columbia | Conformation-specific epitopes in tau, antibodies thereto and methods related thereof |
| GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| KR20230080398A (ko) * | 2020-08-07 | 2023-06-07 | 프로테나 바이오사이언시즈 리미티드 | 알츠하이머 질환 치료용 tau 백신 |
| EP4212172A4 (en) * | 2020-09-08 | 2024-10-16 | Osaka University | Immunogenic composition targeting phosphorylated tau protein |
| EP4400514A4 (en) * | 2021-09-08 | 2025-10-22 | Biocad Joint Stock Co | BISPECIFIC ANTIBODY COMPRISING AN MHC PROTEIN-BASED HETERODIMER |
| WO2023056369A1 (en) * | 2021-09-29 | 2023-04-06 | Janssen Pharmaceuticals, Inc. | Method of safe administration of tau phosphopeptide conjugate |
| CN115894659B (zh) * | 2022-10-19 | 2023-11-10 | 上海优宁维生物科技股份有限公司 | 微管相关蛋白Tau抗原及其制备方法和应用 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| EP0092574B1 (en) | 1981-10-23 | 1992-04-29 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and methods of making same |
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| DE3525624A1 (de) | 1985-07-18 | 1987-01-22 | Celamerck Gmbh & Co Kg | Insektizid wirksames mittel zur bekaempfung von textilschaedlingen |
| US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
| NZ235315A (en) | 1989-09-19 | 1991-09-25 | Wellcome Found | Chimaeric hepadnavirus core antigen proteins and their construction |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| AU9052091A (en) | 1990-12-20 | 1992-07-22 | Smithkline Beecham Biologicals (Sa) | Vaccines based on hepatitis b surface antigen |
| US7408027B1 (en) * | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
| WO1993011231A1 (en) * | 1991-12-06 | 1993-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Tools for the diagnosis and treatment of alzheimer's disease |
| EP0544942A1 (en) * | 1991-12-06 | 1993-06-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel tools for the diagnosis and treatment of Alzheimer disease |
| KR100278157B1 (ko) | 1992-06-25 | 2001-01-15 | 장 스테판느 | 보조약을 함유하는 백신 조성물 |
| SK117395A3 (en) | 1993-03-23 | 1996-11-06 | Smithkline Beecham Biolog | Vaccine composition and manufacturing process thereof |
| DE4321946A1 (de) | 1993-07-01 | 1995-01-12 | Hoechst Ag | Methylphosphonsäureester, Verfahren zu deren Herstellung und deren Verwendung |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5658738A (en) | 1994-05-31 | 1997-08-19 | Becton Dickinson And Company | Bi-directional oligonucleotides that bind thrombin |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| EP1167378B1 (en) | 1994-07-15 | 2011-05-11 | University of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| CN1185811A (zh) | 1995-03-31 | 1998-06-24 | H·沃尔夫 | 依赖于逆转录病毒样颗粒的抗原呈递系统 |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| US20020086009A1 (en) * | 1996-03-13 | 2002-07-04 | Koichi Ishiguro | Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| WO1998016247A1 (en) | 1996-10-11 | 1998-04-23 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| WO1998022120A1 (en) * | 1996-11-19 | 1998-05-28 | The Wistar Institute Of Anatomy & Biology | Diagnostic and therapeutic reagents for alzheimer's disease |
| AUPO517897A0 (en) | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
| EP1039935A4 (en) | 1997-02-28 | 2005-04-27 | Univ Iowa Res Found | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
| DE69841122D1 (de) | 1997-03-10 | 2009-10-15 | Coley Pharm Gmbh | Verwendung von nicht-methyliertem CpG Dinukleotid in Kombination mit Aluminium als Adjuvantien |
| AU7690898A (en) | 1997-05-20 | 1998-12-11 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
| DE69819150T3 (de) | 1997-06-06 | 2007-12-20 | Dynavax Technologies Corp., San Diego | Immunstimulierende oligonucleotide, zusammensetzungen davon, und verfahren zur verwendung davon |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| DE69815692T2 (de) | 1997-09-05 | 2004-04-29 | Glaxosmithkline Biologicals S.A. | Öl in wasser emulsionen mit saponinen |
| CA2320488C (en) | 1998-02-12 | 2007-03-06 | Immune Complex, Corporation | Strategically modified hepatitis b core proteins and their derivatives |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| KR20010042573A (ko) | 1998-04-09 | 2001-05-25 | 장 스테판느 | 애쥬번트 조성물 |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| IL142395A0 (en) | 1998-10-16 | 2002-03-10 | Smithkline Beecham Biolog | Adjuvant systems and vaccines |
| AU770802B2 (en) | 1998-10-21 | 2004-03-04 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Virus-like particles for the induction of autoantibodies |
| CA2349505A1 (en) | 1998-11-05 | 2000-05-11 | Powderject Vaccines, Inc. | Nucleic acid constructs for genetic immunization |
| EP1135162B1 (en) | 1998-11-30 | 2008-10-29 | Cytos Biotechnology AG | Ordered molecular presentation of allergens, method of preparation and use |
| AUPP807399A0 (en) | 1999-01-08 | 1999-02-04 | Csl Limited | Improved immunogenic lhrh composition and methods relating thereto |
| EP1150710B1 (en) | 1999-02-17 | 2010-04-21 | Csl Limited | Immunogenic complexes and methods relating thereto |
| ATE346608T1 (de) | 1999-03-19 | 2006-12-15 | Glaxosmithkline Biolog Sa | Impstoff gegen streptococcus pneumoniae |
| CA2370697C (en) | 1999-04-19 | 2012-03-06 | Smithkline Beecham Biologicals S.A. | Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide |
| MXPA02003068A (es) | 1999-09-24 | 2002-09-30 | Smithkline Beecham Biolog | Adyuvante que comprende un eter o ester alquilo de polioxietileno y al menos un tensioactivo no ionico.. |
| MXPA02003067A (es) | 1999-09-24 | 2002-09-30 | Smithkline Beecham Biolog | Uso de combinacion de ester sorbitano de polioxietileno y octoxinol como adjuvante y su uso en vacunas. |
| KR100808313B1 (ko) | 2000-04-07 | 2008-02-27 | 유니버시티 오브 리즈 이노베이션즈 리미티드 | 비형 간염 코어 항원 융합 단백질 |
| AU2001252458A1 (en) | 2000-05-05 | 2001-11-20 | Martin Bachmann | Molecular antigen arrays and vaccines |
| DE60117978T2 (de) | 2000-06-22 | 2006-11-02 | UCB Pharma Ltd., Slough | Modifizierung des hepatitis b kernantigens |
| AU2001269272A1 (en) | 2000-07-15 | 2002-01-30 | Lighthouse Display International Limited | Shelf edge display fittings |
| AUPQ912000A0 (en) | 2000-07-31 | 2000-08-24 | Crown In The Right Of The Queensland Department Of Health, The | Improved virus like particles |
| US20030138769A1 (en) | 2000-08-16 | 2003-07-24 | Birkett Ashley J. | Immunogenic HBc chimer particles having enhanced stability |
| US7264810B2 (en) * | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| EP1450856B1 (en) | 2001-09-14 | 2009-11-11 | Cytos Biotechnology AG | Packaging of immunostimulatory cpg into virus-like particles: method of preparation and use |
| JP4360906B2 (ja) | 2001-09-14 | 2009-11-11 | サイトス バイオテクノロジー アーゲー | ウィルス様粒子によって誘導される免疫応答を高めるための、抗原提示細胞のインビボでの活性化 |
| AU2003213168A1 (en) | 2002-02-21 | 2003-12-19 | Apovia, Inc. | IMMUNOGENIC HBc CHIMER PARTICLES STABILIZED WITH AN N-TERMINAL CYSTEINE |
| US20040176283A1 (en) | 2002-04-01 | 2004-09-09 | Robinson John A. | Methods and compositions for the design of synthetic vaccines |
| GB0209878D0 (en) | 2002-04-30 | 2002-06-05 | Glaxosmithkline Biolog Sa | Vaccine |
| CN1668637B (zh) | 2002-07-17 | 2010-05-26 | 希托斯生物技术股份公司 | 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列 |
| PT1524994E (pt) * | 2002-07-19 | 2011-08-01 | Cytos Biotechnology Ag | Composições de vacina contendo fileiras de antigénio amilóide beta 1-6 |
| WO2004053091A2 (en) | 2002-12-10 | 2004-06-24 | Lorantis Ltd. | STABILIZED IMMUNOGENIC HBc CHIMER PARTICLES |
| NZ548352A (en) * | 2003-12-17 | 2009-09-25 | Wyeth Corp | Immunogenic peptide carrier conjugates and methods of producing same |
| JP2008506683A (ja) | 2004-07-18 | 2008-03-06 | コーリー ファーマシューティカル グループ, リミテッド | 先天免疫応答を誘導するための方法および組成物 |
| EP2484374A1 (en) | 2004-07-18 | 2012-08-08 | CSL Limited | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
| WO2006040153A2 (en) * | 2004-10-13 | 2006-04-20 | Ablynx N.V. | Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease |
| US8012936B2 (en) * | 2006-03-29 | 2011-09-06 | New York University | Tau fragments for immunotherapy |
| DE602006015421D1 (de) * | 2006-04-13 | 2010-08-26 | Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh | HER-2/neu Multipeptidimpfstoff |
| US20080166785A1 (en) | 2006-08-16 | 2008-07-10 | Monica Sala-Schaeffer | Polynucleotides allowing the expression and secretion of recombinant HBsAg virus-like particles containing a foreign peptide, their production and use |
| EP3329932A1 (en) * | 2009-06-10 | 2018-06-06 | New York University | Immunological targeting of pathological tau proteins |
| FR3058624B1 (fr) | 2016-11-15 | 2018-12-07 | L'oreal | Brosse pour l'application d'un produit sur les cils et/ou les sourcils |
-
2010
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en not_active Ceased
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SG177637A1 (en) | 2012-03-29 |
| TWI461209B (zh) | 2014-11-21 |
| RU2012102701A (ru) | 2013-09-10 |
| JP2013500326A (ja) | 2013-01-07 |
| NZ598356A (en) | 2014-06-27 |
| NZ618391A (en) | 2015-07-31 |
| RU2014112002A (ru) | 2015-10-10 |
| CA2768346A1 (en) | 2011-02-03 |
| EP2459214A1 (en) | 2012-06-06 |
| MX2012001194A (es) | 2012-03-07 |
| PE20120817A1 (es) | 2012-07-07 |
| US20110177109A1 (en) | 2011-07-21 |
| TW201106968A (en) | 2011-03-01 |
| KR20120049900A (ko) | 2012-05-17 |
| TW201436804A (zh) | 2014-10-01 |
| CN102596236A (zh) | 2012-07-18 |
| WO2011013034A4 (en) | 2011-04-28 |
| CO6612199A2 (es) | 2013-02-01 |
| AU2010277254B2 (en) | 2015-05-07 |
| KR20130127547A (ko) | 2013-11-22 |
| CN102596236B (zh) | 2015-06-24 |
| AR078085A1 (es) | 2011-10-12 |
| AU2010277254A1 (en) | 2012-02-09 |
| RU2518291C2 (ru) | 2014-06-10 |
| WO2011013034A1 (en) | 2011-02-03 |
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