AR078085A1 - Peptidos tau antigenicos y usos de los mismos - Google Patents
Peptidos tau antigenicos y usos de los mismosInfo
- Publication number
- AR078085A1 AR078085A1 ARP100102753A ARP100102753A AR078085A1 AR 078085 A1 AR078085 A1 AR 078085A1 AR P100102753 A ARP100102753 A AR P100102753A AR P100102753 A ARP100102753 A AR P100102753A AR 078085 A1 AR078085 A1 AR 078085A1
- Authority
- AR
- Argentina
- Prior art keywords
- tau
- phospho
- epitope
- pser
- pthr
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 abstract 3
- 230000002163 immunogen Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- DCWXELXMIBXGTH-QMMMGPOBSA-N phosphonotyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-QMMMGPOBSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR078085A1 true AR078085A1 (es) | 2011-10-12 |
Family
ID=42941871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100102753A AR078085A1 (es) | 2009-07-30 | 2010-07-29 | Peptidos tau antigenicos y usos de los mismos |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110177109A1 (enExample) |
| EP (1) | EP2459214A1 (enExample) |
| JP (1) | JP2013500326A (enExample) |
| KR (2) | KR20120049900A (enExample) |
| CN (1) | CN102596236B (enExample) |
| AR (1) | AR078085A1 (enExample) |
| AU (1) | AU2010277254B2 (enExample) |
| CA (1) | CA2768346A1 (enExample) |
| CO (1) | CO6612199A2 (enExample) |
| IN (1) | IN2012DN00446A (enExample) |
| MX (1) | MX2012001194A (enExample) |
| NZ (2) | NZ598356A (enExample) |
| PE (1) | PE20120817A1 (enExample) |
| RU (2) | RU2518291C2 (enExample) |
| SG (1) | SG177637A1 (enExample) |
| TW (2) | TWI461209B (enExample) |
| WO (1) | WO2011013034A1 (enExample) |
Families Citing this family (46)
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| CA2745096C (en) | 2008-12-09 | 2013-11-05 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| CN102596221B (zh) | 2009-06-10 | 2019-06-04 | 纽约大学 | 病理tau蛋白的免疫靶向 |
| SI2625198T1 (sl) * | 2010-10-07 | 2015-11-30 | Ac Immune S.A. Epfl Innovation Park | Protitelesa, ki prepoznavajo fosfo-tau |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| ES2714692T3 (es) | 2011-01-31 | 2019-05-29 | Tau Bio Logic Corp | Tratamiento de tauopatías |
| EP2732291B1 (en) | 2011-07-11 | 2017-11-29 | Indi Molecular, Inc. | Akt-specific capture agents, compositions, and methods of using and making |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| RU2639537C2 (ru) | 2011-10-07 | 2017-12-21 | Ац Иммуне С.А. | Фосфоспецифичные антитела, распознающие тау |
| WO2013151762A1 (en) | 2012-04-05 | 2013-10-10 | Ac Immune S.A. | Humanized tau antibody |
| NZ703423A (en) * | 2012-07-03 | 2018-02-23 | Univ Washington | Antibodies to tau |
| SG10201701181XA (en) | 2012-08-16 | 2017-04-27 | Ipierian Inc | Methods of treating a tauopathy |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| BR112015023262B8 (pt) | 2013-03-15 | 2024-02-06 | Ac Immune Sa | Anticorpo isolado, imunoconjugado, formulação farmacêutica e usos do anticorpo |
| WO2015017280A1 (en) * | 2013-07-28 | 2015-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン，インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商Ｃ２Ｎ醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| CN107073297B (zh) | 2014-07-08 | 2021-09-14 | 纽约大学 | Tau显像配体和其在Tau蛋白病的诊断和治疗中的用途 |
| WO2016154522A1 (en) * | 2015-03-25 | 2016-09-29 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
| MX2017015908A (es) | 2015-07-06 | 2018-03-15 | Ucb Biopharma Sprl | Anticuerpos de union a tau. |
| US10988528B2 (en) | 2015-08-13 | 2021-04-27 | New York University | Antibody-based molecules specific for the truncated ASP421 epitope of Tau and their uses in the diagnosis and treatment of tauopathy |
| WO2018064597A1 (en) | 2016-09-29 | 2018-04-05 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| IL302108A (en) | 2017-10-25 | 2023-06-01 | Ac Immune Sa | Preparations of phosphorylated tau peptides and uses thereof |
| MX2020005555A (es) * | 2017-10-27 | 2020-08-20 | United Neuroscience | Construcciones inmunogenicas de peptidos de tau. |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
| GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
| JP7719713B2 (ja) * | 2018-10-07 | 2025-08-06 | ザ ユニヴァーシティ オブ ブリティッシュ コロンビア | α－シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法 |
| CA3129252A1 (en) | 2019-02-08 | 2020-08-13 | Ac Immune S.A. | Method of safe administration of phosphorylated tau peptide vaccine |
| AU2020219374A1 (en) * | 2019-02-08 | 2021-07-01 | Prothena Biosciences Limited | Antibodies recognizing tau |
| US20200291391A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| US11155609B2 (en) | 2019-04-05 | 2021-10-26 | TauC3 Biologies Limited | Anti-TAUC3 antibodies and uses thereof |
| MA55902A (fr) | 2019-04-24 | 2022-03-16 | Ac Immune Sa | Administration hétérologue de vaccins tau |
| WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
| US20220218805A1 (en) * | 2019-05-27 | 2022-07-14 | The University Of British Columbia | Conformation-specific epitopes in tau, antibodies thereto and methods related thereof |
| GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| AU2021321206A1 (en) * | 2020-08-07 | 2023-03-09 | Othair Prothena Limited | Tau vaccine for the treatment of alzheimer's disease |
| EP4212172A4 (en) * | 2020-09-08 | 2024-10-16 | Osaka University | Immunogenic composition targeting phosphorylated tau protein |
| KR20240052854A (ko) * | 2021-09-08 | 2024-04-23 | 조인트 스탁 컴퍼니 "바이오케드" | Mhc 단백질 기반 이종 이량체를 포함하는 이중 특이적 항체 |
| KR20240082368A (ko) * | 2021-09-29 | 2024-06-10 | 얀센 파마슈티칼즈, 인코포레이티드 | 타우 포스포펩티드 접합체의 안전한 투여 방법 |
| CN115894659B (zh) * | 2022-10-19 | 2023-11-10 | 上海优宁维生物科技股份有限公司 | 微管相关蛋白Tau抗原及其制备方法和应用 |
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| EP1517702A4 (en) | 2002-02-21 | 2006-05-03 | Apovia Inc | IMMUNOGENIC HBC CHIMERIC PARTICLES STABILIZED WITH AN N-TERMINAL END CYSTEINE |
| US20040176283A1 (en) | 2002-04-01 | 2004-09-09 | Robinson John A. | Methods and compositions for the design of synthetic vaccines |
| GB0209878D0 (en) | 2002-04-30 | 2002-06-05 | Glaxosmithkline Biolog Sa | Vaccine |
| RU2324704C2 (ru) | 2002-07-17 | 2008-05-20 | Цитос Байотекнолоджи Аг | Молекулярные массивы антигенов |
| EP2338510A1 (en) * | 2002-07-19 | 2011-06-29 | Novartis Pharma AG | Vaccine compositions containing amyloid beta1-6 antigen arrays |
| EP1572234B1 (en) | 2002-12-10 | 2012-02-22 | Sanofi Pasteur Biologics Co. | STABILIZED IMMUNOGENIC HBc CHIMER PARTICLES |
| ES2546175T3 (es) * | 2003-12-17 | 2015-09-21 | Wyeth Llc | Conjugados transportadores de péptidos inmunogénicos y métodos para producirlos |
| CA2574090A1 (en) | 2004-07-18 | 2006-12-21 | Coley Pharmaceutical Group, Ltd. | Methods and compositions for inducing innate immune responses |
| CA2572427A1 (en) | 2004-07-18 | 2006-01-18 | Heather L. Davis | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
| CA2583017A1 (en) * | 2004-10-13 | 2006-04-20 | Ablynx N.V. | Single domain camelide anti-amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenerative neural diseases such as alzheimer's disease |
| US8012936B2 (en) * | 2006-03-29 | 2011-09-06 | New York University | Tau fragments for immunotherapy |
| DE602006015421D1 (de) * | 2006-04-13 | 2010-08-26 | Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh | HER-2/neu Multipeptidimpfstoff |
| US20080166785A1 (en) | 2006-08-16 | 2008-07-10 | Monica Sala-Schaeffer | Polynucleotides allowing the expression and secretion of recombinant HBsAg virus-like particles containing a foreign peptide, their production and use |
| CN102596221B (zh) * | 2009-06-10 | 2019-06-04 | 纽约大学 | 病理tau蛋白的免疫靶向 |
| FR3058624B1 (fr) | 2016-11-15 | 2018-12-07 | L'oreal | Brosse pour l'application d'un produit sur les cils et/ou les sourcils |
-
2010
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en not_active Ceased
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20110177109A1 (en) | 2011-07-21 |
| CN102596236B (zh) | 2015-06-24 |
| TW201106968A (en) | 2011-03-01 |
| RU2518291C2 (ru) | 2014-06-10 |
| RU2014112002A (ru) | 2015-10-10 |
| NZ598356A (en) | 2014-06-27 |
| TWI461209B (zh) | 2014-11-21 |
| TW201436804A (zh) | 2014-10-01 |
| MX2012001194A (es) | 2012-03-07 |
| CN102596236A (zh) | 2012-07-18 |
| WO2011013034A4 (en) | 2011-04-28 |
| CA2768346A1 (en) | 2011-02-03 |
| AU2010277254A1 (en) | 2012-02-09 |
| RU2012102701A (ru) | 2013-09-10 |
| JP2013500326A (ja) | 2013-01-07 |
| EP2459214A1 (en) | 2012-06-06 |
| CO6612199A2 (es) | 2013-02-01 |
| KR20120049900A (ko) | 2012-05-17 |
| AU2010277254B2 (en) | 2015-05-07 |
| IN2012DN00446A (enExample) | 2015-05-15 |
| NZ618391A (en) | 2015-07-31 |
| WO2011013034A1 (en) | 2011-02-03 |
| KR20130127547A (ko) | 2013-11-22 |
| SG177637A1 (en) | 2012-03-29 |
| PE20120817A1 (es) | 2012-07-07 |
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