KR20120034613A - 키나아제 억제제로서 사용을 위한 이미다조피라진 - Google Patents

키나아제 억제제로서 사용을 위한 이미다조피라진 Download PDF

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KR20120034613A
KR20120034613A KR1020117027154A KR20117027154A KR20120034613A KR 20120034613 A KR20120034613 A KR 20120034613A KR 1020117027154 A KR1020117027154 A KR 1020117027154A KR 20117027154 A KR20117027154 A KR 20117027154A KR 20120034613 A KR20120034613 A KR 20120034613A
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호아킨 패스토르 페르난데즈
소니아 마르티네즈 콘잘레스
율렌 오야르자발 산타마리나
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센트로 내셔널 드 인베스티가시오네스 온콜로지카스 (씨엔아이오)
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    • C07ORGANIC CHEMISTRY
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    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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KR1020117027154A 2009-04-16 2010-04-16 키나아제 억제제로서 사용을 위한 이미다조피라진 Ceased KR20120034613A (ko)

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EP09380079 2009-04-16
EP09380079.5 2009-04-16

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KR1020177028146A Division KR101792837B1 (ko) 2009-04-16 2010-04-16 키나아제 억제제로서 사용을 위한 이미다조피라진

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KR1020177028146A Active KR101792837B1 (ko) 2009-04-16 2010-04-16 키나아제 억제제로서 사용을 위한 이미다조피라진

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US (1) US8778935B2 (enExample)
EP (1) EP2419429B1 (enExample)
JP (1) JP5805623B2 (enExample)
KR (2) KR20120034613A (enExample)
CN (1) CN102428087B (enExample)
AU (1) AU2010238361B2 (enExample)
BR (1) BRPI1014572B8 (enExample)
CA (1) CA2756759C (enExample)
DK (1) DK2419429T3 (enExample)
EA (1) EA022629B1 (enExample)
ES (1) ES2475091T3 (enExample)
IL (1) IL215297A (enExample)
MX (1) MX2011010915A (enExample)
NZ (1) NZ596185A (enExample)
SG (1) SG175195A1 (enExample)
WO (1) WO2010119264A1 (enExample)
ZA (1) ZA201107717B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190005876A (ko) * 2016-04-15 2019-01-16 블루프린트 메디신즈 코포레이션 액티빈 수용체 유사 키나아제의 저해제
KR20190095403A (ko) * 2016-12-21 2019-08-14 아세르타 파마. 비.브이. 브루톤 티로신 키나제의 이미다조피라진 저해제

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AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
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KR20190061096A (ko) 2010-04-22 2019-06-04 버텍스 파마슈티칼스 인코포레이티드 시클로알킬카르복스아미도-인돌 화합물의 제조 방법
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WO2012052745A1 (en) 2010-10-21 2012-04-26 Centro Nacional De Investigaciones Oncológicas (Cnio) Combinations of pi3k inhibitors with a second anti -tumor agent
EP2444084A1 (en) 2010-10-21 2012-04-25 Centro Nacional de Investigaciones Oncológicas (CNIO) Use of PI3K inibitors for the treatment of obesity
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AU2013251475B2 (en) 2012-04-26 2018-01-04 The General Hospital Corporation Agents and methods for treating and preventing seborrheic keratosis
CN103450204B (zh) * 2012-05-31 2016-08-17 中国科学院上海药物研究所 吡咯[2,1-f][1,2,4]并三嗪类化合物,其制备方法及用途
CN102675323B (zh) * 2012-06-01 2014-04-09 南京药石药物研发有限公司 吡咯并[2,1-f][1,2,4]三嗪衍生物及其抗肿瘤用途
RU2657540C2 (ru) 2012-06-26 2018-06-14 Янссен Фармацевтика Нв Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств
KR102171706B1 (ko) 2012-07-09 2020-10-30 얀센 파마슈티카 엔.브이. 포스포디에스테라아제 10 효소의 억제제
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KR102421235B1 (ko) 2014-02-13 2022-07-15 인사이트 코포레이션 Lsd1 저해제로서 사이클로프로필아민
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