KR20090105921A - 유전자 분석 시스템 및 방법 - Google Patents

유전자 분석 시스템 및 방법 Download PDF

Info

Publication number
KR20090105921A
KR20090105921A KR1020097013756A KR20097013756A KR20090105921A KR 20090105921 A KR20090105921 A KR 20090105921A KR 1020097013756 A KR1020097013756 A KR 1020097013756A KR 20097013756 A KR20097013756 A KR 20097013756A KR 20090105921 A KR20090105921 A KR 20090105921A
Authority
KR
South Korea
Prior art keywords
individual
phenotype
risk
profile
genotype
Prior art date
Application number
KR1020097013756A
Other languages
English (en)
Korean (ko)
Inventor
디에트리치 에이. 스테판
멜리사 플로렌 필리포네
제니퍼 웨슬
미첼 카길
에란 할페린
Original Assignee
네이비제닉스 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/781,679 external-priority patent/US20080131887A1/en
Application filed by 네이비제닉스 인크. filed Critical 네이비제닉스 인크.
Publication of KR20090105921A publication Critical patent/KR20090105921A/ko

Links

Images

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Ecology (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
KR1020097013756A 2006-11-30 2007-11-30 유전자 분석 시스템 및 방법 KR20090105921A (ko)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US86806606P 2006-11-30 2006-11-30
US60/868,066 2006-11-30
US95112307P 2007-07-20 2007-07-20
US60/951,123 2007-07-20
US11/781,679 2007-07-23
US11/781,679 US20080131887A1 (en) 2006-11-30 2007-07-23 Genetic Analysis Systems and Methods
US97219807P 2007-09-13 2007-09-13
US60/972,198 2007-09-13
US98562207P 2007-11-05 2007-11-05
US60/985,622 2007-11-05
US98968507P 2007-11-21 2007-11-21
US60/989,685 2007-11-21
PCT/US2007/086138 WO2008067551A2 (en) 2006-11-30 2007-11-30 Genetic analysis systems and methods

Publications (1)

Publication Number Publication Date
KR20090105921A true KR20090105921A (ko) 2009-10-07

Family

ID=38962435

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097013756A KR20090105921A (ko) 2006-11-30 2007-11-30 유전자 분석 시스템 및 방법

Country Status (10)

Country Link
EP (1) EP2102651A4 (de)
JP (2) JP2010522537A (de)
KR (1) KR20090105921A (de)
CN (1) CN103642902B (de)
AU (1) AU2007325021B2 (de)
CA (1) CA2671267A1 (de)
GB (1) GB2444410B (de)
HK (1) HK1139737A1 (de)
TW (1) TWI363309B (de)
WO (1) WO2008067551A2 (de)

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101295785B1 (ko) * 2011-10-31 2013-08-12 삼성에스디에스 주식회사 유전변이 데이터 베이스 구축 장치 및 방법
KR20140009854A (ko) * 2012-07-13 2014-01-23 삼성전자주식회사 치료제 선정을 위한 유전 정보의 분석 방법 및 장치
KR20140023607A (ko) * 2012-08-16 2014-02-27 삼성전자주식회사 개인의 유전 정보를 분석하는 방법 및 장치
KR101400946B1 (ko) * 2013-12-27 2014-05-29 한국과학기술정보연구원 생물학적 네트워크 분석 장치 및 방법
WO2014119914A1 (ko) * 2013-02-01 2014-08-07 에스케이텔레콤 주식회사 유전자 서열 기반 개인 마커에 관한 정보를 제공하는 방법 및 이를 이용한 장치
KR101533395B1 (ko) * 2013-01-21 2015-07-08 이상열 단일 염기 다형성을 이용한 개체간의 유사도 산출 방법 및 시스템
KR20150078236A (ko) * 2013-12-30 2015-07-08 주식회사 케이티 개인 건강관리 방법 및 시스템
WO2017014469A1 (ko) * 2015-07-22 2017-01-26 주식회사 케이티 질병 위험도 예측 방법 및 이를 수행하는 장치
WO2017086675A1 (ko) * 2015-11-19 2017-05-26 연세대학교 산학협력단 대사 이상 질환 진단 장치 및 그 방법
KR20170134203A (ko) * 2016-05-27 2017-12-06 (주) 메디젠휴먼케어 Snp를 이용한 질병 관련 유전체 분석 시스템 및 장치
WO2018021636A1 (ko) * 2016-07-29 2018-02-01 (주)신테카바이오 휴먼 하플로타이핑 시스템 및 방법
KR20190019395A (ko) * 2017-08-17 2019-02-27 (주)에이엔티홀딩스 유전자 정보에 기초하여 서비스를 제공하기 위한 방법, 시스템 및 비일시성의 컴퓨터 판독 가능 기록 매체
KR20190077997A (ko) * 2017-12-26 2019-07-04 주식회사 클리노믹스 질병 및 표현형 위험도 예측 장치 및 방법
KR102136207B1 (ko) * 2019-12-31 2020-07-21 주식회사 클리노믹스 유전자 정보 개인 맞춤형 소셜 컨텐츠 정보 제공 시스템 및 그 방법
KR102179850B1 (ko) * 2019-12-06 2020-11-17 주식회사 클리노믹스 구강 내 미생물 분석장치를 이용한 건강 예측 시스템 및 방법
KR20210000070A (ko) * 2019-06-24 2021-01-04 (주) 아이크로진 유전 정보를 이용한 시각화 방법 및 시각화 서비스 플랫폼
KR102223362B1 (ko) * 2020-08-10 2021-03-05 주식회사 쓰리빌리언 증상 연관 유전변이를 이용한 질병 유발 유전변이 발굴 시스템 및 방법
KR102223361B1 (ko) * 2020-09-23 2021-03-05 주식회사 쓰리빌리언 유전자 네트워크를 활용한 유전질병 진단 시스템
WO2021045270A1 (ko) * 2019-09-02 2021-03-11 주식회사 클리노믹스 피검사자와 생물체 간의 유전자 정보를 이용한 유전적 띠 제공 시스템 및 그 방법
WO2021112319A1 (ko) * 2019-12-06 2021-06-10 주식회사 클리노믹스 게놈 정보를 이용한 유전적 성씨 정보 제공 시스템 및 방법
WO2021137563A1 (ko) * 2020-01-02 2021-07-08 주식회사 클리노믹스 국가, 민족, 및 인종별 표준게놈지도를 이용한 정체성 분석 서비스 제공 방법

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8340950B2 (en) 2006-02-10 2012-12-25 Affymetrix, Inc. Direct to consumer genotype-based products and services
US20080131887A1 (en) 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
US7972787B2 (en) 2007-02-16 2011-07-05 Massachusetts Eye And Ear Infirmary Methods for detecting age-related macular degeneration
US20080228700A1 (en) 2007-03-16 2008-09-18 Expanse Networks, Inc. Attribute Combination Discovery
FR2934698B1 (fr) * 2008-08-01 2011-11-18 Commissariat Energie Atomique Procede de prediction pour le pronostic ou le diagnostic ou la reponse therapeutique d'une maladie et notamment du cancer de la prostate et dispositif permettant la mise en oeuvre du procede.
AU2009279434A1 (en) * 2008-08-08 2010-02-11 Navigenics, Inc. Methods and systems for personalized action plans
KR20110074527A (ko) * 2008-09-12 2011-06-30 네이비제닉스 인크. 복수의 환경 및 유전 위험 인자를 통합하기 위한 방법 및 시스템
NZ572036A (en) 2008-10-15 2010-03-26 Nikola Kirilov Kasabov Data analysis and predictive systems and related methodologies
WO2010067381A1 (en) * 2008-12-12 2010-06-17 Decode Genetics Ehf Genetic variants as markers for use in diagnosis, prognosis and treatment of eosinophilia, asthma, and myocardial infarction
US8108406B2 (en) 2008-12-30 2012-01-31 Expanse Networks, Inc. Pangenetic web user behavior prediction system
US8463554B2 (en) 2008-12-31 2013-06-11 23Andme, Inc. Finding relatives in a database
CA2760439A1 (en) 2009-04-30 2010-11-04 Good Start Genetics, Inc. Methods and compositions for evaluating genetic markers
EP2438193B1 (de) * 2009-06-01 2015-07-22 Genetic Technologies Limited Verfahren zur brustkrebsrisikobewertung
DE102010013114B4 (de) * 2010-03-26 2012-02-16 Rüdiger Lawaczeck Prädiagnostisches Sicherheitssystem
KR20110136638A (ko) * 2010-06-15 2011-12-21 재단법인 게놈연구재단 게놈정보를 이용하여 온라인 상의 사회적 네트워크를 형성하는 시스템 및 그 형성방법
WO2012006669A1 (en) * 2010-07-13 2012-01-19 Fitgenes Pty Ltd System and method for determining personal health intervention
WO2012030967A1 (en) * 2010-08-31 2012-03-08 Knome, Inc. Personal genome indexer
WO2012054653A2 (en) 2010-10-19 2012-04-26 Medtronic, Inc. Diagnostic kits, genetic markers, and methods for scd or sca therapy selection
WO2012059839A2 (en) * 2010-11-01 2012-05-10 Koninklijke Philips Electronics N.V. In vitro diagnostic testing including automated brokering of royalty payments for proprietary tests
US9163281B2 (en) 2010-12-23 2015-10-20 Good Start Genetics, Inc. Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
US8718950B2 (en) 2011-07-08 2014-05-06 The Medical College Of Wisconsin, Inc. Methods and apparatus for identification of disease associated mutations
US20140310215A1 (en) * 2011-09-26 2014-10-16 John Trakadis Method and system for genetic trait search based on the phenotype and the genome of a human subject
US10378060B2 (en) 2011-10-14 2019-08-13 Dana-Farber Cancer Institute, Inc. ZNF365/ZFP365 biomarker predictive of anti-cancer response
US10437858B2 (en) 2011-11-23 2019-10-08 23Andme, Inc. Database and data processing system for use with a network-based personal genetics services platform
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
JP5844715B2 (ja) 2012-11-07 2016-01-20 学校法人沖縄科学技術大学院大学学園 データ通信システム、データ解析装置、データ通信方法、および、プログラム
EP2971159B1 (de) 2013-03-14 2019-05-08 Molecular Loop Biosolutions, LLC Verfahren zur analyse von nukleinsäuren
US20140274763A1 (en) * 2013-03-15 2014-09-18 Pathway Genomics Corporation Method and system to predict response to pain treatments
US9192647B2 (en) 2013-10-04 2015-11-24 Hans-Michael Dosch Method for reversing recent-onset type 1 diabetes (T1D) by administering substance P (sP)
TW201516725A (zh) * 2013-10-18 2015-05-01 Tci Gene Inc 單一核苷酸多型性疾病發生率預測系統
US10851414B2 (en) 2013-10-18 2020-12-01 Good Start Genetics, Inc. Methods for determining carrier status
FI20136079A (fi) * 2013-11-04 2015-05-05 Medisapiens Oy Menetelmä ja järjestelmä geeniperimän terveyden arvioimiseksi
DE202014010499U1 (de) 2013-12-17 2015-10-20 Kymab Limited Targeting von humaner PCSK9 zur Cholesterinbehandlung
CN106460062A (zh) 2014-05-05 2017-02-22 美敦力公司 用于scd、crt、crt‑d或sca治疗识别和/或选择的方法和组合物
WO2015175530A1 (en) 2014-05-12 2015-11-19 Gore Athurva Methods for detecting aneuploidy
EP4328245A3 (de) 2014-07-15 2024-06-05 Kymab Ltd. Antikörper zur verwendung bei der behandlung von erkrankungen im zusammenhang mit spezifischen pcsk9-varianten in bestimmten patientenpopulationen
DE202015009007U1 (de) 2014-07-15 2016-08-19 Kymab Limited Targeting von humaner PCSK9 zur Cholesterinbehandlung
EP2975059A1 (de) 2014-07-15 2016-01-20 Kymab Limited Antikörper zur anwendung zur behandlung von spezifischen pcsk9 varianten bezogenen erkrankungen in spezifischen patientengruppen
WO2016023916A1 (en) 2014-08-12 2016-02-18 Kymab Limited Treatment of disease using ligand binding to targets of interest
ES2898435T3 (es) * 2014-09-03 2022-03-07 Otsuka Pharma Co Ltd Dispositivo de ayuda para la determinación de patología, método, programa y medio de almacenamiento
US11408024B2 (en) 2014-09-10 2022-08-09 Molecular Loop Biosciences, Inc. Methods for selectively suppressing non-target sequences
JP2017536087A (ja) 2014-09-24 2017-12-07 グッド スタート ジェネティクス， インコーポレイテッド 遺伝子アッセイのロバストネスを増大させるためのプロセス制御
WO2016071701A1 (en) 2014-11-07 2016-05-12 Kymab Limited Treatment of disease using ligand binding to targets of interest
EP4095261A1 (de) 2015-01-06 2022-11-30 Molecular Loop Biosciences, Inc. Abtasten auf strukturelle varianten
CN107548498A (zh) 2015-01-20 2018-01-05 南托米克斯有限责任公司 用于反应预测高级别膀胱癌中的化疗的系统和方法
CA2975529A1 (en) * 2015-02-09 2016-08-18 10X Genomics, Inc. Systems and methods for determining structural variation and phasing using variant call data
CA2978708A1 (en) * 2015-03-03 2016-09-09 Nantomics, Llc Ensemble-based research recommendation systems and methods
CA3035342A1 (en) * 2015-09-16 2017-03-23 Good Start Genetics, Inc. Systems and methods for medical genetic testing
AU2016324166A1 (en) * 2015-09-18 2018-05-10 Omicia, Inc. Predicting disease burden from genome variants
FR3045874B1 (fr) * 2015-12-18 2019-06-14 Axlr, Satt Du Languedoc Roussillon Architecture pour l'analyse de donnees genomiques
JP6776576B2 (ja) * 2016-03-28 2020-10-28 富士通株式会社 データベース処理プログラム、データベース処理装置及びデータベース処理方法
EP3479272A1 (de) * 2016-06-29 2019-05-08 Koninklijke Philips N.V. Krankheitsausgerichtete genomische anonymisierung
WO2018042185A1 (en) * 2016-09-02 2018-03-08 Imperial Innovations Ltd Methods, systems and apparatus for identifying pathogenic gene variants
CN106778083A (zh) * 2016-11-28 2017-05-31 墨宝股份有限公司 一种自动生成基因检测报告的方法及装置
EP3553737A4 (de) * 2016-12-12 2019-11-06 Nec Corporation Informationsverarbeitungsvorrichtung, verfahren zur erzeugung genetischer informationen und programm
CN108884488A (zh) * 2017-03-15 2018-11-23 东洋纺株式会社 基因检测方法及基因检测试剂盒
CN108629153A (zh) * 2017-03-23 2018-10-09 广州康昕瑞基因健康科技有限公司 医学基因分析方法和系统
WO2019028507A1 (en) * 2017-08-08 2019-02-14 Queensland University Of Technology METHODS OF DIAGNOSING PRECOCUS STAGES OF CARDIAC INSUFFICIENCY
CN108549795A (zh) * 2018-03-13 2018-09-18 刘吟 基于家系图框架的遗传咨询信息系统
GB201810897D0 (en) * 2018-07-03 2018-08-15 Chronomics Ltd Phenotype prediction
CN109355368A (zh) * 2018-10-22 2019-02-19 江苏美因康生物科技有限公司 一种快速检测高血压个体化用药基因多态性的试剂盒及方法
US10896742B2 (en) 2018-10-31 2021-01-19 Ancestry.Com Dna, Llc Estimation of phenotypes using DNA, pedigree, and historical data
GB2578727A (en) * 2018-11-05 2020-05-27 Earlham Inst Genomic analysis
WO2020132456A1 (en) * 2018-12-20 2020-06-25 The Johns Hopkins University Treating type 1 diabetes, other autoimmune diseases
JP7137520B2 (ja) * 2019-04-23 2022-09-14 ジェネシスヘルスケア株式会社 膵炎のリスクを判定する方法
JP7137526B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 アトピー性皮膚炎のリスクを判定する方法
JP7137524B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 変形性膝関節症のリスクを判定する方法
JP7137521B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 乾癬のリスクを判定する方法
JP7137525B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 接触性皮膚炎のリスクを判定する方法
JP7137522B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 脊椎側弯症のリスクを判定する方法
JP7137523B2 (ja) * 2019-04-24 2022-09-14 ジェネシスヘルスケア株式会社 じんましんのリスクを判定する方法
CN113921143B (zh) * 2021-10-08 2024-04-16 天津金域医学检验实验室有限公司 一种共分离分析中Bayes因子的个性化估算方法及系统
CN114360732B (zh) * 2022-01-12 2024-04-09 平安科技（深圳）有限公司 医疗数据分析方法、装置、电子设备及存储介质

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000067139A (ja) * 1998-08-25 2000-03-03 Hitachi Ltd 電子カルテシステム
EP2899660A1 (de) * 1999-08-27 2015-07-29 Iris Biotechnologies Inc. System mit künstlicher Intelligenz zur genetischen Analyse
WO2001026029A2 (en) * 1999-10-01 2001-04-12 Orchid Biosciences, Inc. Method and system for providing genotype clinical information over a computer network
US20020133495A1 (en) * 2000-03-16 2002-09-19 Rienhoff Hugh Y. Database system and method
JP2002107366A (ja) * 2000-10-02 2002-04-10 Hitachi Ltd 診断支援システム
AU2001297684A1 (en) * 2000-12-04 2002-08-19 Genaissance Pharmaceuticals, Inc. System and method for the management of genomic data
US20020128860A1 (en) * 2001-01-04 2002-09-12 Leveque Joseph A. Collecting and managing clinical information
US20020187483A1 (en) * 2001-04-20 2002-12-12 Cerner Corporation Computer system for providing information about the risk of an atypical clinical event based upon genetic information
US7461006B2 (en) * 2001-08-29 2008-12-02 Victor Gogolak Method and system for the analysis and association of patient-specific and population-based genomic data with drug safety adverse event data
US20030104453A1 (en) * 2001-11-06 2003-06-05 David Pickar System for pharmacogenetics of adverse drug events
US20040053263A1 (en) * 2002-08-30 2004-03-18 Abreu Maria T. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
WO2004109551A1 (ja) * 2003-06-05 2004-12-16 Hitachi High-Technologies Corporation 塩基配列関連情報を用いた情報提供システム及びプログラム
GB0313964D0 (en) * 2003-06-16 2003-07-23 Mars Inc Genotype test
US7084264B2 (en) * 2003-07-16 2006-08-01 Chau-Ting Yeh Viral sequences
US8222005B2 (en) * 2003-09-17 2012-07-17 Agency For Science, Technology And Research Method for gene identification signature (GIS) analysis
KR20060130039A (ko) * 2003-10-15 2006-12-18 가부시끼가이샤 사인포스트 질환 위험도 판정용 유전자 다형의 결정 방법, 질환 위험도판정 방법 및 판정용 어레이
US20050214811A1 (en) * 2003-12-12 2005-09-29 Margulies David M Processing and managing genetic information
US7127355B2 (en) * 2004-03-05 2006-10-24 Perlegen Sciences, Inc. Methods for genetic analysis
JP2008506372A (ja) * 2004-07-16 2008-03-06 バイエル・ヘルスケア・アクチェンゲゼルシャフト 薬物有害反応（ａｄｒ）および薬効を診断するための予測ツールとしての一塩基多型
WO2006053955A2 (en) * 2004-11-19 2006-05-26 Oy Jurilab Ltd Method and kit for detecting a risk of essential arterial hypertension

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101295785B1 (ko) * 2011-10-31 2013-08-12 삼성에스디에스 주식회사 유전변이 데이터 베이스 구축 장치 및 방법
KR20140009854A (ko) * 2012-07-13 2014-01-23 삼성전자주식회사 치료제 선정을 위한 유전 정보의 분석 방법 및 장치
KR20140023607A (ko) * 2012-08-16 2014-02-27 삼성전자주식회사 개인의 유전 정보를 분석하는 방법 및 장치
KR101533395B1 (ko) * 2013-01-21 2015-07-08 이상열 단일 염기 다형성을 이용한 개체간의 유사도 산출 방법 및 시스템
WO2014119914A1 (ko) * 2013-02-01 2014-08-07 에스케이텔레콤 주식회사 유전자 서열 기반 개인 마커에 관한 정보를 제공하는 방법 및 이를 이용한 장치
US9984184B2 (en) 2013-12-27 2018-05-29 Korea Institute Of Science And Technology Information Biological network analysis device and method therefor
KR101400946B1 (ko) * 2013-12-27 2014-05-29 한국과학기술정보연구원 생물학적 네트워크 분석 장치 및 방법
WO2015099264A1 (ko) * 2013-12-27 2015-07-02 한국과학기술정보연구원 생물학적 네트워크 분석 장치 및 방법
KR20150078236A (ko) * 2013-12-30 2015-07-08 주식회사 케이티 개인 건강관리 방법 및 시스템
WO2017014469A1 (ko) * 2015-07-22 2017-01-26 주식회사 케이티 질병 위험도 예측 방법 및 이를 수행하는 장치
KR20170011389A (ko) * 2015-07-22 2017-02-02 주식회사 케이티 질병 위험도 예측 방법 및 이를 수행하는 장치
WO2017086675A1 (ko) * 2015-11-19 2017-05-26 연세대학교 산학협력단 대사 이상 질환 진단 장치 및 그 방법
KR20170134203A (ko) * 2016-05-27 2017-12-06 (주) 메디젠휴먼케어 Snp를 이용한 질병 관련 유전체 분석 시스템 및 장치
KR20190080832A (ko) * 2016-05-27 2019-07-08 (주) 메디젠휴먼케어 Snp를 이용한 질병 관련 유전체 분석 시스템 및 장치
WO2018021636A1 (ko) * 2016-07-29 2018-02-01 (주)신테카바이오 휴먼 하플로타이핑 시스템 및 방법
US10540324B2 (en) 2016-07-29 2020-01-21 Syntekabio Co., Ltd. Human haplotyping system and method
KR20190019395A (ko) * 2017-08-17 2019-02-27 (주)에이엔티홀딩스 유전자 정보에 기초하여 서비스를 제공하기 위한 방법, 시스템 및 비일시성의 컴퓨터 판독 가능 기록 매체
WO2019035691A3 (ko) * 2017-08-17 2019-07-04 (주)에이엔티홀딩스 유전자 정보에 기초하여 서비스를 제공하기 위한 방법, 시스템 및 비일시성의 컴퓨터 판독 가능 기록 매체
KR20190077997A (ko) * 2017-12-26 2019-07-04 주식회사 클리노믹스 질병 및 표현형 위험도 예측 장치 및 방법
KR20210000070A (ko) * 2019-06-24 2021-01-04 (주) 아이크로진 유전 정보를 이용한 시각화 방법 및 시각화 서비스 플랫폼
WO2021045270A1 (ko) * 2019-09-02 2021-03-11 주식회사 클리노믹스 피검사자와 생물체 간의 유전자 정보를 이용한 유전적 띠 제공 시스템 및 그 방법
KR102179850B1 (ko) * 2019-12-06 2020-11-17 주식회사 클리노믹스 구강 내 미생물 분석장치를 이용한 건강 예측 시스템 및 방법
WO2021112317A1 (ko) * 2019-12-06 2021-06-10 주식회사 클리노믹스 구강 내 미생물 분석장치를 이용한 건강 예측 시스템 및 방법
WO2021112319A1 (ko) * 2019-12-06 2021-06-10 주식회사 클리노믹스 게놈 정보를 이용한 유전적 성씨 정보 제공 시스템 및 방법
KR102136207B1 (ko) * 2019-12-31 2020-07-21 주식회사 클리노믹스 유전자 정보 개인 맞춤형 소셜 컨텐츠 정보 제공 시스템 및 그 방법
WO2021137539A1 (ko) * 2019-12-31 2021-07-08 주식회사 클리노믹스 유전자 정보 개인 맞춤형 소셜 컨텐츠 정보 제공 시스템 및 그 방법
WO2021137563A1 (ko) * 2020-01-02 2021-07-08 주식회사 클리노믹스 국가, 민족, 및 인종별 표준게놈지도를 이용한 정체성 분석 서비스 제공 방법
KR102223362B1 (ko) * 2020-08-10 2021-03-05 주식회사 쓰리빌리언 증상 연관 유전변이를 이용한 질병 유발 유전변이 발굴 시스템 및 방법
KR102223361B1 (ko) * 2020-09-23 2021-03-05 주식회사 쓰리빌리언 유전자 네트워크를 활용한 유전질병 진단 시스템

Also Published As

Publication number Publication date
TWI363309B (en) 2012-05-01
CN103642902B (zh) 2016-01-20
CA2671267A1 (en) 2008-06-05
HK1139737A1 (en) 2010-09-24
JP2010522537A (ja) 2010-07-08
AU2007325021B2 (en) 2013-05-09
GB2444410A (en) 2008-06-04
EP2102651A4 (de) 2010-11-17
JP2014140387A (ja) 2014-08-07
EP2102651A2 (de) 2009-09-23
WO2008067551A2 (en) 2008-06-05
GB2444410B (en) 2011-08-24
WO2008067551A3 (en) 2008-12-11
AU2007325021A1 (en) 2008-06-05
TW200847056A (en) 2008-12-01
GB0723512D0 (en) 2008-01-09
CN103642902A (zh) 2014-03-19

Similar Documents

Publication Publication Date Title
KR20090105921A (ko) 유전자 분석 시스템 및 방법
TWI423063B (zh) 用於個人化行為計劃之方法及系統
JP5491400B2 (ja) 祖先データを用いるゲノム解析の方法及びシステム
TWI423151B (zh) 結合多個環境及基因風險因子的方法及系統
Bush et al. Unravelling the human genome–phenome relationship using phenome-wide association studies
US9092391B2 (en) Genetic analysis systems and methods
Begg et al. Variation of breast cancer risk among BRCA1/2 carriers
Misganaw et al. Polygenic risk associated with post-traumatic stress disorder onset and severity
Mégarbané et al. Developmental delay, intellectual disability, short stature, subglottic stenosis, hearing impairment, onychodysplasia of the index fingers, and distinctive facial features: A newly reported autosomal recessive syndrome
Leighton Population-based Genotype-phenotype Correlation to Stratify Incident Cases of Motor Neurone Disease in Scotland, from 2015-2017
Zeng et al. A scalable EHR-based approach for phenotype discovery and variant interpretation for hereditary cancer genes
Umlai Application of Genomics for the Precision Molecular Diagnosis of Rare Short Stature Disorders
Burook et al. Polygenic risk associated with post-traumatic stress disorder onset and severity
Desiderio et al. Wiley series on mass spectrometry
DClinPsy et al. Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic
Munafò et al. CRUK Integrative Cancer Epidemiology Programme

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid