GB2444410B - Genetic analysis systems and methods - Google Patents
Genetic analysis systems and methodsInfo
- Publication number
- GB2444410B GB2444410B GB0723512A GB0723512A GB2444410B GB 2444410 B GB2444410 B GB 2444410B GB 0723512 A GB0723512 A GB 0723512A GB 0723512 A GB0723512 A GB 0723512A GB 2444410 B GB2444410 B GB 2444410B
- Authority
- GB
- United Kingdom
- Prior art keywords
- individual
- disease
- information
- correlations
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000012252 genetic analysis Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000002068 genetic effect Effects 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 206010074026 Exfoliation glaucoma Diseases 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
- G16B50/30—Data warehousing; Computing architectures
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G06F19/18—
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/40—Population genetics; Linkage disequilibrium
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Bioethics (AREA)
- Databases & Information Systems (AREA)
- Ecology (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
Abstract
A method or system for assessing phenotypes, such as a disease or a susceptibility to a disease, of an individual's genomic information, such as single nucleotide polymorphisms (SNPs), comprises comparing a genomic profile of the individual with a database of genotype/phenotype correlations. reporting the results back to the individual, updating the database with newly discovered correlations and/or new genomic data and reporting the revised correlations back to the individual. Multiple genetic markers, together with other information, are combined to produce a Genetic Composite Index (GCI) score. An on-line portals comprising a website allows individuals to access and analyse the information. Methods for determining predisposition to, in particular, Alzheimer's Disease, colorectal cancer, osteoarthritis or exfoliation glaucoma, based on specific SNP markers, are provided.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86806606P | 2006-11-30 | 2006-11-30 | |
US95112307P | 2007-07-20 | 2007-07-20 | |
US11/781,679 US20080131887A1 (en) | 2006-11-30 | 2007-07-23 | Genetic Analysis Systems and Methods |
US97219807P | 2007-09-13 | 2007-09-13 | |
US98562207P | 2007-11-05 | 2007-11-05 | |
US98968507P | 2007-11-21 | 2007-11-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
GB0723512D0 GB0723512D0 (en) | 2008-01-09 |
GB2444410A GB2444410A (en) | 2008-06-04 |
GB2444410B true GB2444410B (en) | 2011-08-24 |
Family
ID=38962435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB0723512A Active GB2444410B (en) | 2006-11-30 | 2007-11-30 | Genetic analysis systems and methods |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP2102651A4 (en) |
JP (2) | JP2010522537A (en) |
KR (1) | KR20090105921A (en) |
CN (1) | CN103642902B (en) |
AU (1) | AU2007325021B2 (en) |
CA (1) | CA2671267A1 (en) |
GB (1) | GB2444410B (en) |
HK (1) | HK1139737A1 (en) |
TW (1) | TWI363309B (en) |
WO (1) | WO2008067551A2 (en) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8340950B2 (en) | 2006-02-10 | 2012-12-25 | Affymetrix, Inc. | Direct to consumer genotype-based products and services |
US20080131887A1 (en) | 2006-11-30 | 2008-06-05 | Stephan Dietrich A | Genetic Analysis Systems and Methods |
WO2008103299A2 (en) | 2007-02-16 | 2008-08-28 | Massachusetts Eye & Ear Infirmary | Methods and compositions for prognosing, detecting, and treating age-related macular degeneration |
US7844609B2 (en) | 2007-03-16 | 2010-11-30 | Expanse Networks, Inc. | Attribute combination discovery |
FR2934698B1 (en) * | 2008-08-01 | 2011-11-18 | Commissariat Energie Atomique | PREDICTION METHOD FOR THE PROGNOSIS OR DIAGNOSIS OR THERAPEUTIC RESPONSE OF A DISEASE AND IN PARTICULAR PROSTATE CANCER AND DEVICE FOR PERFORMING THE METHOD. |
CN102171697A (en) * | 2008-08-08 | 2011-08-31 | 纳维哲尼克斯公司 | Methods and systems for personalized action plans |
EP2335174A1 (en) * | 2008-09-12 | 2011-06-22 | Navigenics INC. | Methods and systems for incorporating multiple environmental and genetic risk factors |
NZ572036A (en) | 2008-10-15 | 2010-03-26 | Nikola Kirilov Kasabov | Data analysis and predictive systems and related methodologies |
US8367333B2 (en) * | 2008-12-12 | 2013-02-05 | Decode Genetics Ehf. | Genetic variants as markers for use in diagnosis, prognosis and treatment of eosinophilia, asthma, and myocardial infarction |
US8108406B2 (en) | 2008-12-30 | 2012-01-31 | Expanse Networks, Inc. | Pangenetic web user behavior prediction system |
EP3276526A1 (en) | 2008-12-31 | 2018-01-31 | 23Andme, Inc. | Finding relatives in a database |
CA2760439A1 (en) | 2009-04-30 | 2010-11-04 | Good Start Genetics, Inc. | Methods and compositions for evaluating genetic markers |
EP2438193B1 (en) * | 2009-06-01 | 2015-07-22 | Genetic Technologies Limited | Methods for breast cancer risk assessment |
DE102010013114B4 (en) * | 2010-03-26 | 2012-02-16 | Rüdiger Lawaczeck | Prediagnostic safety system |
KR20110136638A (en) * | 2010-06-15 | 2011-12-21 | 재단법인 게놈연구재단 | Online social network construction method and system with personal genome data |
WO2012006669A1 (en) * | 2010-07-13 | 2012-01-19 | Fitgenes Pty Ltd | System and method for determining personal health intervention |
WO2012030967A1 (en) * | 2010-08-31 | 2012-03-08 | Knome, Inc. | Personal genome indexer |
US20120309641A1 (en) | 2010-10-19 | 2012-12-06 | Medtronic, Inc. | Diagnostic kits, genetic markers, and methods for scd or sca therapy selection |
CN103314383A (en) * | 2010-11-01 | 2013-09-18 | 皇家飞利浦电子股份有限公司 | In vitro diagnostic testing including automated brokering of royalty payments for proprietary tests |
US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
US8718950B2 (en) | 2011-07-08 | 2014-05-06 | The Medical College Of Wisconsin, Inc. | Methods and apparatus for identification of disease associated mutations |
US20140310215A1 (en) * | 2011-09-26 | 2014-10-16 | John Trakadis | Method and system for genetic trait search based on the phenotype and the genome of a human subject |
WO2013055911A1 (en) | 2011-10-14 | 2013-04-18 | Dana-Farber Cancer Institute, Inc. | Znf365/zfp365 biomarker predictive of anti-cancer response |
KR101295785B1 (en) * | 2011-10-31 | 2013-08-12 | 삼성에스디에스 주식회사 | Apparatus and Method for Constructing Gene-Disease Relation Database |
US10437858B2 (en) | 2011-11-23 | 2019-10-08 | 23Andme, Inc. | Database and data processing system for use with a network-based personal genetics services platform |
US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
KR20140009854A (en) * | 2012-07-13 | 2014-01-23 | 삼성전자주식회사 | Method and apparatus for analyzing gene information for treatment decision |
KR101967248B1 (en) * | 2012-08-16 | 2019-04-10 | 삼성전자주식회사 | Method and apparatus for analyzing personalized multi-omics data |
JP5844715B2 (en) | 2012-11-07 | 2016-01-20 | 学校法人沖縄科学技術大学院大学学園 | Data communication system, data analysis apparatus, data communication method, and program |
KR101533395B1 (en) * | 2013-01-21 | 2015-07-08 | 이상열 | Method and system estimating resemblance between subject using single nucleotide polymorphism |
WO2014119914A1 (en) * | 2013-02-01 | 2014-08-07 | 에스케이텔레콤 주식회사 | Method for providing information about gene sequence-based personal marker and apparatus using same |
WO2014152421A1 (en) | 2013-03-14 | 2014-09-25 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
US20140274763A1 (en) * | 2013-03-15 | 2014-09-18 | Pathway Genomics Corporation | Method and system to predict response to pain treatments |
US9192647B2 (en) | 2013-10-04 | 2015-11-24 | Hans-Michael Dosch | Method for reversing recent-onset type 1 diabetes (T1D) by administering substance P (sP) |
TW201516725A (en) * | 2013-10-18 | 2015-05-01 | Tci Gene Inc | Single nucleotide polymorphism disease incidence prediction system |
US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
FI20136079A (en) * | 2013-11-04 | 2015-05-05 | Medisapiens Oy | Genetic health assessment procedure and system |
DE202014010499U1 (en) | 2013-12-17 | 2015-10-20 | Kymab Limited | Targeting of human PCSK9 for cholesterol treatment |
KR101400946B1 (en) * | 2013-12-27 | 2014-05-29 | 한국과학기술정보연구원 | Biological network analyzing device and method thereof |
KR102131973B1 (en) * | 2013-12-30 | 2020-07-08 | 주식회사 케이티 | Method and System for personalized healthcare |
CN106460062A (en) | 2014-05-05 | 2017-02-22 | 美敦力公司 | Methods and compositions for SCD, CRT, CRT-D, or SCA therapy identification and/or selection |
US11053548B2 (en) | 2014-05-12 | 2021-07-06 | Good Start Genetics, Inc. | Methods for detecting aneuploidy |
EP4328245A3 (en) | 2014-07-15 | 2024-06-05 | Kymab Ltd. | Antibodies for use in treating conditions related to specific pcsk9 variants in specific patients populations |
DE202015009002U1 (en) | 2014-07-15 | 2016-08-18 | Kymab Limited | Targeting of human PCSK9 for cholesterol treatment |
EP2975059A1 (en) | 2014-07-15 | 2016-01-20 | Kymab Limited | Antibodies for use in treating conditions related to specific pcsk9 variants in specific patients populations |
WO2016023916A1 (en) | 2014-08-12 | 2016-02-18 | Kymab Limited | Treatment of disease using ligand binding to targets of interest |
US20180032673A1 (en) * | 2014-09-03 | 2018-02-01 | Otsuka Pharmaceutical Co., Ltd. | Pathology determination assistance device, method and storage medium |
WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
CA2999708A1 (en) | 2014-09-24 | 2016-03-31 | Good Start Genetics, Inc. | Process control for increased robustness of genetic assays |
WO2016071701A1 (en) | 2014-11-07 | 2016-05-12 | Kymab Limited | Treatment of disease using ligand binding to targets of interest |
CA3010579A1 (en) | 2015-01-06 | 2016-07-14 | Good Start Genetics, Inc. | Screening for structural variants |
WO2016118527A1 (en) | 2015-01-20 | 2016-07-28 | Nantomics, Llc | Systems and methods for response prediction to chemotherapy in high grade bladder cancer |
EP3256606B1 (en) * | 2015-02-09 | 2019-05-22 | 10X Genomics, Inc. | Systems and methods for determining structural variation |
KR20190047108A (en) * | 2015-03-03 | 2019-05-07 | 난토믹스, 엘엘씨 | Ensemble-based Research Recommendation Systems and Methods |
KR102508971B1 (en) * | 2015-07-22 | 2023-03-09 | 주식회사 케이티 | Method and apparatus for predicting the disease risk |
CA3035342A1 (en) * | 2015-09-16 | 2017-03-23 | Good Start Genetics, Inc. | Systems and methods for medical genetic testing |
EP3350721A4 (en) * | 2015-09-18 | 2019-06-12 | Fabric Genomics, Inc. | Predicting disease burden from genome variants |
KR101795662B1 (en) * | 2015-11-19 | 2017-11-13 | 연세대학교 산학협력단 | Apparatus and Method for Diagnosis of metabolic disease |
FR3045874B1 (en) * | 2015-12-18 | 2019-06-14 | Axlr, Satt Du Languedoc Roussillon | ARCHITECTURE FOR GENOMIC DATA ANALYSIS |
JP6776576B2 (en) * | 2016-03-28 | 2020-10-28 | 富士通株式会社 | Database processing program, database processing device and database processing method |
KR101991007B1 (en) * | 2016-05-27 | 2019-06-20 | (주)메디젠휴먼케어 | A system and apparatus for disease-related genomic analysis using SNP |
EP3479272A1 (en) * | 2016-06-29 | 2019-05-08 | Koninklijke Philips N.V. | Disease-oriented genomic anonymization |
KR101815529B1 (en) | 2016-07-29 | 2018-01-30 | (주)신테카바이오 | Human Haplotyping System And Method |
WO2018042185A1 (en) * | 2016-09-02 | 2018-03-08 | Imperial Innovations Ltd | Methods, systems and apparatus for identifying pathogenic gene variants |
CN106778083A (en) * | 2016-11-28 | 2017-05-31 | 墨宝股份有限公司 | A kind of method and device for automatically generating genetic test report |
WO2018110490A1 (en) * | 2016-12-12 | 2018-06-21 | 日本電気株式会社 | Information processing device, genetic information creation method, and program |
JP7264046B2 (en) * | 2017-03-15 | 2023-04-25 | 東洋紡株式会社 | Genetic test method and genetic test kit |
CN108629153A (en) * | 2017-03-23 | 2018-10-09 | 广州康昕瑞基因健康科技有限公司 | Cma gene analysis method and system |
AU2018315056B2 (en) * | 2017-08-08 | 2021-06-17 | Queensland University Of Technology | Methods for diagnosis of early stage heart failure |
KR102073590B1 (en) * | 2017-08-17 | 2020-02-06 | (주)에이엔티홀딩스 | Method, system and non-transitory computer-readable recording medium for providing a service based on genetic information |
KR102097540B1 (en) * | 2017-12-26 | 2020-04-07 | 주식회사 클리노믹스 | Method for disease and phenotype risk score calculation |
CN108549795A (en) * | 2018-03-13 | 2018-09-18 | 刘吟 | Genetic counselling information system based on pedigree chart frame |
GB201810897D0 (en) * | 2018-07-03 | 2018-08-15 | Chronomics Ltd | Phenotype prediction |
CN109355368A (en) * | 2018-10-22 | 2019-02-19 | 江苏美因康生物科技有限公司 | A kind of kit and method of quick detection hypertension individuation medication gene pleiomorphism |
EP3874510A4 (en) | 2018-10-31 | 2022-08-03 | Ancestry.com DNA, LLC | Estimation of phenotypes using dna, pedigree, and historical data |
GB2578727A (en) * | 2018-11-05 | 2020-05-27 | Earlham Inst | Genomic analysis |
EP3899039A4 (en) * | 2018-12-20 | 2022-09-14 | The Johns Hopkins University | Treating type 1 diabetes, other autoimmune diseases |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001016860A2 (en) * | 1999-08-27 | 2001-03-08 | Iris Bio Technologies, Inc. | Artificial intelligence system for genetic analysis |
WO2001026029A2 (en) * | 1999-10-01 | 2001-04-12 | Orchid Biosciences, Inc. | Method and system for providing genotype clinical information over a computer network |
JP2002107366A (en) * | 2000-10-02 | 2002-04-10 | Hitachi Ltd | Diagnosis-assisting system |
WO2002063415A2 (en) * | 2000-12-04 | 2002-08-15 | Genaissance Pharmaceuticals, Inc. | System and method for the management of genomic data |
WO2002086663A2 (en) * | 2001-04-20 | 2002-10-31 | Cerner Corporation | Computer system fro providing information about the risk of an atypical clinical event based upon genetic information |
US20050037399A1 (en) * | 2003-07-16 | 2005-02-17 | Chau-Ting Yeh | Novel viral sequences |
US20050196770A1 (en) * | 2004-03-05 | 2005-09-08 | Perlegen Sciences, Inc. | Methods for genetic analysis |
EP1684202A1 (en) * | 2003-10-15 | 2006-07-26 | Signpost Corporation | Method of determining genetic polymorphism for judgment of degree of disease risk, method of judging degree of disease risk, and judgment array |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000067139A (en) * | 1998-08-25 | 2000-03-03 | Hitachi Ltd | Electronic medical sheet system |
US20030208454A1 (en) * | 2000-03-16 | 2003-11-06 | Rienhoff Hugh Y. | Method and system for populating a database for further medical characterization |
US20020128860A1 (en) * | 2001-01-04 | 2002-09-12 | Leveque Joseph A. | Collecting and managing clinical information |
US7461006B2 (en) * | 2001-08-29 | 2008-12-02 | Victor Gogolak | Method and system for the analysis and association of patient-specific and population-based genomic data with drug safety adverse event data |
AU2002363329A1 (en) * | 2001-11-06 | 2003-05-19 | Elizabeth Gray | Pharmacogenomics-based system for clinical applications |
US20040053263A1 (en) * | 2002-08-30 | 2004-03-18 | Abreu Maria T. | Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease |
JPWO2004109551A1 (en) * | 2003-06-05 | 2006-07-20 | 株式会社日立ハイテクノロジーズ | Information providing system and program using base sequence related information |
GB0313964D0 (en) * | 2003-06-16 | 2003-07-23 | Mars Inc | Genotype test |
US8222005B2 (en) * | 2003-09-17 | 2012-07-17 | Agency For Science, Technology And Research | Method for gene identification signature (GIS) analysis |
US20050214811A1 (en) * | 2003-12-12 | 2005-09-29 | Margulies David M | Processing and managing genetic information |
CA2573945A1 (en) * | 2004-07-16 | 2006-01-26 | Bayer Healthcare Ag | Single nucleotide polymorphisms as prognostic tool to diagnose adverse drug reactions (adr) and drug efficacy |
WO2006053955A2 (en) * | 2004-11-19 | 2006-05-26 | Oy Jurilab Ltd | Method and kit for detecting a risk of essential arterial hypertension |
-
2007
- 2007-11-30 GB GB0723512A patent/GB2444410B/en active Active
- 2007-11-30 CN CN201310565723.1A patent/CN103642902B/en active Active
- 2007-11-30 TW TW096145856A patent/TWI363309B/en not_active IP Right Cessation
- 2007-11-30 AU AU2007325021A patent/AU2007325021B2/en not_active Ceased
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- 2007-11-30 WO PCT/US2007/086138 patent/WO2008067551A2/en active Application Filing
- 2007-11-30 JP JP2009539519A patent/JP2010522537A/en active Pending
- 2007-11-30 CA CA002671267A patent/CA2671267A1/en not_active Abandoned
- 2007-11-30 EP EP07854875A patent/EP2102651A4/en not_active Ceased
-
2010
- 2010-06-30 HK HK10106416.1A patent/HK1139737A1/en not_active IP Right Cessation
-
2014
- 2014-05-16 JP JP2014102062A patent/JP2014140387A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001016860A2 (en) * | 1999-08-27 | 2001-03-08 | Iris Bio Technologies, Inc. | Artificial intelligence system for genetic analysis |
WO2001026029A2 (en) * | 1999-10-01 | 2001-04-12 | Orchid Biosciences, Inc. | Method and system for providing genotype clinical information over a computer network |
JP2002107366A (en) * | 2000-10-02 | 2002-04-10 | Hitachi Ltd | Diagnosis-assisting system |
WO2002063415A2 (en) * | 2000-12-04 | 2002-08-15 | Genaissance Pharmaceuticals, Inc. | System and method for the management of genomic data |
WO2002086663A2 (en) * | 2001-04-20 | 2002-10-31 | Cerner Corporation | Computer system fro providing information about the risk of an atypical clinical event based upon genetic information |
US20050037399A1 (en) * | 2003-07-16 | 2005-02-17 | Chau-Ting Yeh | Novel viral sequences |
EP1684202A1 (en) * | 2003-10-15 | 2006-07-26 | Signpost Corporation | Method of determining genetic polymorphism for judgment of degree of disease risk, method of judging degree of disease risk, and judgment array |
US20050196770A1 (en) * | 2004-03-05 | 2005-09-08 | Perlegen Sciences, Inc. | Methods for genetic analysis |
Non-Patent Citations (1)
Title |
---|
Environmental Health Perspectives (e-pub 13 Nov 2006); Vol 15, pp 231-234, "A statistical model for assessing genetic...", Demchuk et al * |
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JP2010522537A (en) | 2010-07-08 |
CN103642902A (en) | 2014-03-19 |
AU2007325021A1 (en) | 2008-06-05 |
GB0723512D0 (en) | 2008-01-09 |
TWI363309B (en) | 2012-05-01 |
WO2008067551A2 (en) | 2008-06-05 |
EP2102651A2 (en) | 2009-09-23 |
CA2671267A1 (en) | 2008-06-05 |
KR20090105921A (en) | 2009-10-07 |
EP2102651A4 (en) | 2010-11-17 |
JP2014140387A (en) | 2014-08-07 |
WO2008067551A3 (en) | 2008-12-11 |
CN103642902B (en) | 2016-01-20 |
HK1139737A1 (en) | 2010-09-24 |
AU2007325021B2 (en) | 2013-05-09 |
GB2444410A (en) | 2008-06-04 |
TW200847056A (en) | 2008-12-01 |
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