KR20090082422A - 트라이포스겐 (ｂｔｃ)에 의한 당의 염소화에 의한 수크랄로스의 제조 방법 - Google Patents

트라이포스겐 (ｂｔｃ)에 의한 당의 염소화에 의한 수크랄로스의 제조 방법

Info

Publication number
KR20090082422A
KR20090082422A KR1020097010474A KR20097010474A KR20090082422A KR 20090082422 A KR20090082422 A KR 20090082422A KR 1020097010474 A KR1020097010474 A KR 1020097010474A KR 20097010474 A KR20097010474 A KR 20097010474A KR 20090082422 A KR20090082422 A KR 20090082422A
Authority
KR
South Korea
Prior art keywords
sucrose
btc
ester
dmf
chlorination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020097010474A
Other languages
English (en)
Korean (ko)
Inventor
데이비드 로산 호
정하오 완
Original Assignee
맘테크 인터내셔널 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 맘테크 인터내셔널 리미티드 filed Critical 맘테크 인터내셔널 리미티드
Publication of KR20090082422A publication Critical patent/KR20090082422A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K5/00—Lactose
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K7/00—Maltose

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020097010474A 2006-10-25 2007-10-24 트라이포스겐 (ｂｔｃ)에 의한 당의 염소화에 의한 수크랄로스의 제조 방법 Withdrawn KR20090082422A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/552,789 2006-10-25
US11/552,789 US8258291B2 (en) 2006-10-25 2006-10-25 Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)

Publications (1)

Publication Number Publication Date
KR20090082422A true KR20090082422A (ko) 2009-07-30

Family

ID=39325402

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097010474A Withdrawn KR20090082422A (ko) 2006-10-25 2007-10-24 트라이포스겐 (ｂｔｃ)에 의한 당의 염소화에 의한 수크랄로스의 제조 방법

Country Status (19)

Country Link
US (1) US8258291B2 (enExample)
EP (1) EP2094873B1 (enExample)
JP (1) JP2010508285A (enExample)
KR (1) KR20090082422A (enExample)
CN (1) CN101631878A (enExample)
AT (1) ATE515509T1 (enExample)
AU (1) AU2007308947A1 (enExample)
BR (1) BRPI0718178A2 (enExample)
CA (1) CA2667419A1 (enExample)
CY (1) CY1112434T1 (enExample)
DK (1) DK2094873T3 (enExample)
ES (1) ES2366063T3 (enExample)
MX (1) MX2009004355A (enExample)
PL (1) PL2094873T3 (enExample)
PT (1) PT2094873E (enExample)
RU (1) RU2009119515A (enExample)
SI (1) SI2094873T1 (enExample)
TW (1) TW200833706A (enExample)
WO (1) WO2008052076A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US7862744B2 (en) * 2008-07-23 2011-01-04 Mamtek International Limited Methods and systems for preparing materials for sucralose production
CA2817630C (en) 2010-11-23 2019-09-03 Lexington Pharmaceuticals Laboratories, Llc Low temperature chlorination of carbohydrates
US8884004B2 (en) 2011-09-02 2014-11-11 Divi's Laboratories, Ltd. Process for the preparation of sucralose
DK2646452T3 (da) 2011-10-14 2016-06-20 Lexington Pharmaceutical Laboratories Llc Chlorering af carbohydrater og carbohydratderivater
CN103087116A (zh) * 2011-11-07 2013-05-08 常茂生物化学工程股份有限公司 三氯蔗糖的制备方法
CN104774227A (zh) * 2015-04-08 2015-07-15 常州市牛塘化工厂有限公司 一种蔗糖-6-乙酯的氯化方法
WO2016194001A1 (en) * 2015-05-29 2016-12-08 Alaparthi Lakshmi Prasad Processes for preparation of sugammadex and intermediates thereof
CN105153248A (zh) * 2015-08-28 2015-12-16 山东康宝生化科技有限公司 在固体光气法合成三氯蔗糖6乙酯过程中的温度控制方法
CN105111250A (zh) * 2015-08-28 2015-12-02 山东康宝生化科技有限公司 一种利用固体光气进行三氯蔗糖6乙酯的制备方法
JP6815932B2 (ja) * 2017-05-31 2021-01-20 株式会社トクヤマ Ｎ−カルバメート保護カルボキシ無水物の製造方法
CN108203452B (zh) * 2018-01-24 2021-04-06 山东康宝生化科技有限公司 一种合成三氯蔗糖-6-乙酯的方法
CN110950888B (zh) * 2019-11-11 2022-05-20 山东省科学院菏泽分院 一种Vilsmeier试剂参与的氯噁酮的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072725A (en) * 1960-11-14 1963-01-08 Du Pont Preparation of dimethylformamide
DE3165986D1 (en) * 1980-07-08 1984-10-18 Tate & Lyle Plc Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs)
GB8818430D0 (en) * 1988-08-03 1988-09-07 Tate & Lyle Plc Process
US4980463A (en) * 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
JP3002885B2 (ja) 1989-11-02 2000-01-24 住友化学工業株式会社 ジメチルホルムアミドの回収精製法
JP3514495B2 (ja) * 1992-10-02 2004-03-31 エーザイ株式会社 ハロゲン化アミノチアジアゾリル酢酸誘導体の製造法
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
EP1076661A1 (en) * 1998-05-15 2001-02-21 Rostislav G. Zhbankov Method of preparation of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
HU228576B1 (en) * 1998-10-20 2013-04-29 Lundbeck & Co As H Method for the preparation of citalopram
US6998480B2 (en) * 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
CN1176094C (zh) 2003-05-23 2004-11-17 广东省食品工业研究所 一种三氯蔗糖的合成方法
US20060205936A1 (en) * 2005-03-14 2006-09-14 Sl Laboratories, Llc Chlorination of Sucrose-6-esters
US20090030193A1 (en) * 2005-05-04 2009-01-29 Pharmed Medicare Private Limited Synthesis of Vilsmeier Haack Reagent from Di(Trichlo-Romethyl) Carbonate for Chlorination Reaction
US7951937B2 (en) 2005-08-30 2011-05-31 V.B. Medicare Private Limited Process for purification of trichlorogalactosucrose based on direct extraction in organic solvent from reaction mixture followed by evaporative removal of solvent
US20090264640A1 (en) 2006-05-23 2009-10-22 V.B. Medicare Pvt. Ltd Recovery of dimethylformamide and other solvents from process streams of manufacture of trichlorogalactosucrose
US20080103295A1 (en) 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst

Also Published As

Publication number Publication date
EP2094873B1 (en) 2011-07-06
PT2094873E (pt) 2011-08-24
RU2009119515A (ru) 2010-11-27
AU2007308947A1 (en) 2008-05-02
DK2094873T3 (da) 2011-08-15
SI2094873T1 (sl) 2011-12-30
CA2667419A1 (en) 2008-05-02
TW200833706A (en) 2008-08-16
CN101631878A (zh) 2010-01-20
ATE515509T1 (de) 2011-07-15
EP2094873A4 (en) 2009-11-25
ES2366063T3 (es) 2011-10-14
JP2010508285A (ja) 2010-03-18
WO2008052076A2 (en) 2008-05-02
CY1112434T1 (el) 2015-12-09
BRPI0718178A2 (pt) 2013-12-17
WO2008052076B1 (en) 2008-09-12
US20080103298A1 (en) 2008-05-01
PL2094873T3 (pl) 2011-10-31
MX2009004355A (es) 2009-08-25
EP2094873A2 (en) 2009-09-02
US8258291B2 (en) 2012-09-04
WO2008052076A3 (en) 2008-07-17

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20090522

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid