KR20080112340A - 커큐민의 합성 - Google Patents

커큐민의 합성 Download PDF

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Publication number
KR20080112340A
KR20080112340A KR1020087026287A KR20087026287A KR20080112340A KR 20080112340 A KR20080112340 A KR 20080112340A KR 1020087026287 A KR1020087026287 A KR 1020087026287A KR 20087026287 A KR20087026287 A KR 20087026287A KR 20080112340 A KR20080112340 A KR 20080112340A
Authority
KR
South Korea
Prior art keywords
curcumin
vanillin
acetylacetone
water
entrainer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020087026287A
Other languages
English (en)
Korean (ko)
Inventor
크리스토프 베흘리
Original Assignee
디에스엠 아이피 어셋츠 비.브이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 디에스엠 아이피 어셋츠 비.브이. filed Critical 디에스엠 아이피 어셋츠 비.브이.
Publication of KR20080112340A publication Critical patent/KR20080112340A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
    • C07C49/248—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
KR1020087026287A 2006-03-29 2007-03-19 커큐민의 합성 Ceased KR20080112340A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06006519.0 2006-03-29
EP06006519 2006-03-29

Publications (1)

Publication Number Publication Date
KR20080112340A true KR20080112340A (ko) 2008-12-24

Family

ID=38093544

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087026287A Ceased KR20080112340A (ko) 2006-03-29 2007-03-19 커큐민의 합성

Country Status (7)

Country Link
US (1) US7964755B2 (enExample)
EP (1) EP1999097B1 (enExample)
JP (1) JP5341747B2 (enExample)
KR (1) KR20080112340A (enExample)
CN (1) CN101454267B (enExample)
AT (1) ATE538080T1 (enExample)
WO (1) WO2007110168A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101952422A (zh) 2007-12-27 2011-01-19 巴克斯特国际公司 化学修饰的因子ix
US8680143B2 (en) 2008-07-07 2014-03-25 Laila Pharmaceuticals Pvt. Ltd. Orally active curcuminoid compounds
EP2857379B1 (en) * 2012-05-08 2020-09-02 Asac Compañía De Biotecnología E Investigación SA Method for the synthesis of curcumin
CN102701934A (zh) * 2012-05-30 2012-10-03 江南大学 一种以氧化锌负载氧化镁为催化剂催化合成姜黄素的方法
CN102701933A (zh) * 2012-05-30 2012-10-03 江南大学 一种采用氧化铝负载氟化钾固体碱催化合成姜黄素的方法
CN102911022B (zh) * 2012-10-25 2015-12-09 山东鲁诺动物药业有限公司 一种天然姜黄素类物的人工合成方法
CN103910615A (zh) * 2014-04-09 2014-07-09 西安雅森生物技术有限公司 一种合成姜黄素的方法
CN108101761B (zh) * 2017-12-08 2021-08-03 陕西嘉禾生物科技股份有限公司 一种姜黄素的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL255427A (enExample) * 1959-08-31
DE3821197A1 (de) * 1988-06-23 1989-12-28 Basf Ag Verfahren zur herstellung von (alpha),(beta)-ungesaettigten ketonen
US5679864A (en) 1995-11-03 1997-10-21 Gene Print Inc. Process for the synthesis of curcumin-related compounds

Also Published As

Publication number Publication date
CN101454267B (zh) 2012-09-26
WO2007110168A1 (en) 2007-10-04
ATE538080T1 (de) 2012-01-15
CN101454267A (zh) 2009-06-10
EP1999097A1 (en) 2008-12-10
EP1999097B1 (en) 2011-12-21
US7964755B2 (en) 2011-06-21
US20100312015A1 (en) 2010-12-09
JP2009531353A (ja) 2009-09-03
JP5341747B2 (ja) 2013-11-13

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Date Code Title Description
PA0105 International application

Patent event date: 20081027

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20111226

Comment text: Request for Examination of Application

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PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20130711

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20131008

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20130711

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I