KR20070011458A - 키나제의 벤조트리아진 억제제 - Google Patents
키나제의 벤조트리아진 억제제 Download PDFInfo
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- KR20070011458A KR20070011458A KR1020067023392A KR20067023392A KR20070011458A KR 20070011458 A KR20070011458 A KR 20070011458A KR 1020067023392 A KR1020067023392 A KR 1020067023392A KR 20067023392 A KR20067023392 A KR 20067023392A KR 20070011458 A KR20070011458 A KR 20070011458A
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- 0 Cc1cc(-c2cc(*C3NC3)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(N(C)CCN1CCCC1)(=O)=O)nn2 Chemical compound Cc1cc(-c2cc(*C3NC3)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(N(C)CCN1CCCC1)(=O)=O)nn2 0.000 description 7
- FNLOXZWNBHKDHT-UHFFFAOYSA-N C/C=S(/c1cc(Nc2nc(c(C)cc(-c3cc(O)ccc3Cl)c3)c3nn2)ccc1)\NCCN(C)C Chemical compound C/C=S(/c1cc(Nc2nc(c(C)cc(-c3cc(O)ccc3Cl)c3)c3nn2)ccc1)\NCCN(C)C FNLOXZWNBHKDHT-UHFFFAOYSA-N 0.000 description 1
- CZJQXIJQVQAMQY-UHFFFAOYSA-N C/C=S(\c1cccc(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1)/NCCN1CCCC1 Chemical compound C/C=S(\c1cccc(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1)/NCCN1CCCC1 CZJQXIJQVQAMQY-UHFFFAOYSA-N 0.000 description 1
- ABUMAALIRMJYKL-UHFFFAOYSA-N CC(C1)C(Nc(nnc2c3)nc2c(C)cc3-c2c(C)cccc2C)=CC=C1OCCCN1CCN(C)CC1 Chemical compound CC(C1)C(Nc(nnc2c3)nc2c(C)cc3-c2c(C)cccc2C)=CC=C1OCCCN1CCN(C)CC1 ABUMAALIRMJYKL-UHFFFAOYSA-N 0.000 description 1
- PFVCCMOOCGLRPV-ZBEWQZTPSA-N CC1(C)OB(/C(/C=N)=C/N)OC1(C)C Chemical compound CC1(C)OB(/C(/C=N)=C/N)OC1(C)C PFVCCMOOCGLRPV-ZBEWQZTPSA-N 0.000 description 1
- RWHGLLOSNOBOAG-UHFFFAOYSA-N CC1C=CC=C(C)C1c(cc1C)cc2c1nc(Nc1ccc(C3(CC3)C#N)cc1)nn2 Chemical compound CC1C=CC=C(C)C1c(cc1C)cc2c1nc(Nc1ccc(C3(CC3)C#N)cc1)nn2 RWHGLLOSNOBOAG-UHFFFAOYSA-N 0.000 description 1
- RWWXMAISBSXVJW-UHFFFAOYSA-N CCS(c1cc(NC2(C)N=Nc(cc(cc3C)-c4c(C)cccc4C)c3N2)ccc1)N1CCN(C)CC1 Chemical compound CCS(c1cc(NC2(C)N=Nc(cc(cc3C)-c4c(C)cccc4C)c3N2)ccc1)N1CCN(C)CC1 RWWXMAISBSXVJW-UHFFFAOYSA-N 0.000 description 1
- OHOCYSFPKSCDCC-UHFFFAOYSA-N COc(cc(c1c2)N=C(N)[N-][NH+]1[O-])c2Br Chemical compound COc(cc(c1c2)N=C(N)[N-][NH+]1[O-])c2Br OHOCYSFPKSCDCC-UHFFFAOYSA-N 0.000 description 1
- URMHCJJAQHPSHE-UHFFFAOYSA-N Cc(c(-c(cc1C)cc2c1nc(Nc1cnccc1)nn2)c1)ccc1O Chemical compound Cc(c(-c(cc1C)cc2c1nc(Nc1cnccc1)nn2)c1)ccc1O URMHCJJAQHPSHE-UHFFFAOYSA-N 0.000 description 1
- SCSUWQZPGBAANL-UHFFFAOYSA-O Cc(c(C1=CNCC=C1Cl)c1)cc2c1N[NH2+]C(Nc1ccc(C(N3CCN(C)CC3)O)cc1)=N2 Chemical compound Cc(c(C1=CNCC=C1Cl)c1)cc2c1N[NH2+]C(Nc1ccc(C(N3CCN(C)CC3)O)cc1)=N2 SCSUWQZPGBAANL-UHFFFAOYSA-O 0.000 description 1
- ZZFQEPHEJPYQRX-UHFFFAOYSA-N Cc(cc1N=C(Nc(cc2)ccc2S(NCCN2CCCC2)(=O)=O)N(C)Nc1c1)c1N(CCC1)CC1O Chemical compound Cc(cc1N=C(Nc(cc2)ccc2S(NCCN2CCCC2)(=O)=O)N(C)Nc1c1)c1N(CCC1)CC1O ZZFQEPHEJPYQRX-UHFFFAOYSA-N 0.000 description 1
- LABCTTMUCCQJOL-UHFFFAOYSA-N Cc(cc1nc(Nc(cc2)ccc2S(NCCN2CCCC2)(=O)=O)nnc1c1)c1-c1ccc(CO)[s]1 Chemical compound Cc(cc1nc(Nc(cc2)ccc2S(NCCN2CCCC2)(=O)=O)nnc1c1)c1-c1ccc(CO)[s]1 LABCTTMUCCQJOL-UHFFFAOYSA-N 0.000 description 1
- KPQNUXDKYZNGIH-UHFFFAOYSA-N Cc(ccc(OC(c1ccccc1)=O)c1)c1-c1cc(C)c2nc(Nc(cc3)ccc3S(NCCN3CCCC3)=O)nnc2c1 Chemical compound Cc(ccc(OC(c1ccccc1)=O)c1)c1-c1cc(C)c2nc(Nc(cc3)ccc3S(NCCN3CCCC3)=O)nnc2c1 KPQNUXDKYZNGIH-UHFFFAOYSA-N 0.000 description 1
- ODUZZNIXCWMHDQ-UHFFFAOYSA-N Cc(cccc1)c1-c(cc(c(N=C(N)[N-]1)c2)[N+]1(C)[O-])c2OC Chemical compound Cc(cccc1)c1-c(cc(c(N=C(N)[N-]1)c2)[N+]1(C)[O-])c2OC ODUZZNIXCWMHDQ-UHFFFAOYSA-N 0.000 description 1
- IGVIZKFUQQWEII-UHFFFAOYSA-N Cc1cc(-c(c(Cl)ccc2)c2Cl)cc2c1nc(Nc(cc1)ccc1OC)nn2 Chemical compound Cc1cc(-c(c(Cl)ccc2)c2Cl)cc2c1nc(Nc(cc1)ccc1OC)nn2 IGVIZKFUQQWEII-UHFFFAOYSA-N 0.000 description 1
- CSXVLYGUGWXOAL-UHFFFAOYSA-N Cc1cc(-c(c(Cl)ccc2O)c2F)cc2c1nc(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)nn2 Chemical compound Cc1cc(-c(c(Cl)ccc2O)c2F)cc2c1nc(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)nn2 CSXVLYGUGWXOAL-UHFFFAOYSA-N 0.000 description 1
- KQSFXNJAOKXFFH-UHFFFAOYSA-N Cc1cc(-c(c(Cl)ccc2OC)c2Cl)cc2c1nc(Nc(cc1)ccc1S(C(CC1)CCN1C(OCc1ccccc1)=O)O)nn2 Chemical compound Cc1cc(-c(c(Cl)ccc2OC)c2Cl)cc2c1nc(Nc(cc1)ccc1S(C(CC1)CCN1C(OCc1ccccc1)=O)O)nn2 KQSFXNJAOKXFFH-UHFFFAOYSA-N 0.000 description 1
- JFPQJONXEVRXFI-UHFFFAOYSA-N Cc1cc(-c(cc(cc2)OC)c2Cl)cc2c1nc(N)nn2 Chemical compound Cc1cc(-c(cc(cc2)OC)c2Cl)cc2c1nc(N)nn2 JFPQJONXEVRXFI-UHFFFAOYSA-N 0.000 description 1
- VAWLAPYBUJTXRS-UHFFFAOYSA-N Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(C1CCNCC1)(=O)=O)nn2 Chemical compound Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(C1CCNCC1)(=O)=O)nn2 VAWLAPYBUJTXRS-UHFFFAOYSA-N 0.000 description 1
- RCZHVXSTTOXWRM-UHFFFAOYSA-N Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(CCCN1CCCC1)(=O)=O)nn2 Chemical compound Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(CCCN1CCCC1)(=O)=O)nn2 RCZHVXSTTOXWRM-UHFFFAOYSA-N 0.000 description 1
- ZBRROTSBDAODQD-UHFFFAOYSA-N Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)nn2 Chemical compound Cc1cc(-c2cc(O)ccc2Cl)cc2c1nc(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)nn2 ZBRROTSBDAODQD-UHFFFAOYSA-N 0.000 description 1
- OHSRGSMDJHRVCW-UHFFFAOYSA-N Cc1cc(-c2cc(OC)ccc2Cl)cc2c1nc(Nc(cc1)ccc1C(N1CCN(C)CC1)=O)nn2 Chemical compound Cc1cc(-c2cc(OC)ccc2Cl)cc2c1nc(Nc(cc1)ccc1C(N1CCN(C)CC1)=O)nn2 OHSRGSMDJHRVCW-UHFFFAOYSA-N 0.000 description 1
- UDKAJCCCEMHMRL-UHFFFAOYSA-N Cc1cc(-c2cccc(O)c2F)cc2c1N=C(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)N(C)N2 Chemical compound Cc1cc(-c2cccc(O)c2F)cc2c1N=C(Nc(cc1)ccc1S(NCCN1CCCC1)(=O)=O)N(C)N2 UDKAJCCCEMHMRL-UHFFFAOYSA-N 0.000 description 1
- SEGUBAOUZUWQIU-UHFFFAOYSA-N Cc1cc2nc(Nc(cc3)ccc3S(NCCN3CCCC3)(=O)=O)nnc2cc1-c1c[nH]nc1 Chemical compound Cc1cc2nc(Nc(cc3)ccc3S(NCCN3CCCC3)(=O)=O)nnc2cc1-c1c[nH]nc1 SEGUBAOUZUWQIU-UHFFFAOYSA-N 0.000 description 1
- PALCXSSPRKLOQR-UHFFFAOYSA-N Cc1ccc(C)c(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1 Chemical compound Cc1ccc(C)c(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1 PALCXSSPRKLOQR-UHFFFAOYSA-N 0.000 description 1
- OYVBTDSVIPSNGN-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1)cc2c1nc(Nc1ccccc1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1)cc2c1nc(Nc1ccccc1)nn2 OYVBTDSVIPSNGN-UHFFFAOYSA-N 0.000 description 1
- NCCBXUNIYZFBJX-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OC)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OC)nn2 NCCBXUNIYZFBJX-UHFFFAOYSA-N 0.000 description 1
- YJSFAHMGDRBZGH-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OCCN1CCCC1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OCCN1CCCC1)nn2 YJSFAHMGDRBZGH-UHFFFAOYSA-N 0.000 description 1
- LRRYSZJODUIJIM-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OCCN1CCN(C)CC1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1OCCN1CCN(C)CC1)nn2 LRRYSZJODUIJIM-UHFFFAOYSA-N 0.000 description 1
- GGNXJUYBBQRVPK-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1S(N(C)CCN1CCCC1)(=O)=O)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1S(N(C)CCN1CCCC1)(=O)=O)nn2 GGNXJUYBBQRVPK-UHFFFAOYSA-N 0.000 description 1
- OSEIUQRJBFSSJX-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cn1)ccc1OC)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc(cn1)ccc1OC)nn2 OSEIUQRJBFSSJX-UHFFFAOYSA-N 0.000 description 1
- NGGCCTYGNWOTDF-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccc(C(NCCCN3CCCC3)=O)[o]1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccc(C(NCCCN3CCCC3)=O)[o]1)nn2 NGGCCTYGNWOTDF-UHFFFAOYSA-N 0.000 description 1
- XARNNPFETIANRB-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1cccc(OC)c1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1cccc(OC)c1)nn2 XARNNPFETIANRB-UHFFFAOYSA-N 0.000 description 1
- YHHHJKZCRBUOTD-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccnc(OCCN3CCCC3)c1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccnc(OCCN3CCCC3)c1)nn2 YHHHJKZCRBUOTD-UHFFFAOYSA-N 0.000 description 1
- ZJQVYURHZFRKLA-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccncc1)nn2 Chemical compound Cc1cccc(C)c1-c(cc1C)cc2c1nc(Nc1ccncc1)nn2 ZJQVYURHZFRKLA-UHFFFAOYSA-N 0.000 description 1
- ADXGPZOSBKVNNC-UHFFFAOYSA-N Cc1cccc(C)c1-c(cc1[N+](C)([O-])O)cc2c1N=C(Nc(cc1)ccc1OCCN1CCCC1)[NH+]2[OH2+] Chemical compound Cc1cccc(C)c1-c(cc1[N+](C)([O-])O)cc2c1N=C(Nc(cc1)ccc1OCCN1CCCC1)[NH+]2[OH2+] ADXGPZOSBKVNNC-UHFFFAOYSA-N 0.000 description 1
- PVMYJIUXPSAQRU-UHFFFAOYSA-N Cc1cccc(Cl)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1O)nn2 Chemical compound Cc1cccc(Cl)c1-c(cc1C)cc2c1nc(Nc(cc1)ccc1O)nn2 PVMYJIUXPSAQRU-UHFFFAOYSA-N 0.000 description 1
- BCFAJUIGPMLBBZ-UHFFFAOYSA-N Cc1cccc(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1 Chemical compound Cc1cccc(Nc2nc(c(C)cc(-c3c(C)cccc3C)c3)c3nn2)c1 BCFAJUIGPMLBBZ-UHFFFAOYSA-N 0.000 description 1
- SOHGBCJRAJJOHG-UHFFFAOYSA-N Cc1cccc(Nc2nc(c(C)cc(-c3cc(OC)cc(OC)c3)c3)c3nn2)c1C Chemical compound Cc1cccc(Nc2nc(c(C)cc(-c3cc(OC)cc(OC)c3)c3)c3nn2)c1C SOHGBCJRAJJOHG-UHFFFAOYSA-N 0.000 description 1
- NSJVYHOPHZMZPN-UHFFFAOYSA-N Cc1ccccc1B(O)O Chemical compound Cc1ccccc1B(O)O NSJVYHOPHZMZPN-UHFFFAOYSA-N 0.000 description 1
- RRQNWZSUEPXFBD-UHFFFAOYSA-N NC(N)=NC(C1)C(NO)=CC(Br)=C1Cl Chemical compound NC(N)=NC(C1)C(NO)=CC(Br)=C1Cl RRQNWZSUEPXFBD-UHFFFAOYSA-N 0.000 description 1
- BDXAJMMKEDNEDS-UHFFFAOYSA-O NC([NH2+]1)=Nc(cc(cc2)Cl)c2N1O Chemical compound NC([NH2+]1)=Nc(cc(cc2)Cl)c2N1O BDXAJMMKEDNEDS-UHFFFAOYSA-O 0.000 description 1
- ZCWXYZBQDNFULS-UHFFFAOYSA-N Nc1cc(Cl)ccc1[N+]([O-])=O Chemical compound Nc1cc(Cl)ccc1[N+]([O-])=O ZCWXYZBQDNFULS-UHFFFAOYSA-N 0.000 description 1
- HWWNZYNBPKPHKD-UHFFFAOYSA-N O=C(N(CC1)CCC1S(c(cc1)ccc1Br)(=O)=O)OCc1ccccc1 Chemical compound O=C(N(CC1)CCC1S(c(cc1)ccc1Br)(=O)=O)OCc1ccccc1 HWWNZYNBPKPHKD-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56123704P | 2004-04-08 | 2004-04-08 | |
US60/561,237 | 2004-04-08 | ||
US64343905P | 2005-01-12 | 2005-01-12 | |
US60/643,439 | 2005-01-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20070011458A true KR20070011458A (ko) | 2007-01-24 |
Family
ID=35125563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020067023392A KR20070011458A (ko) | 2004-04-08 | 2005-04-07 | 키나제의 벤조트리아진 억제제 |
Country Status (10)
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7208493B2 (en) * | 2002-10-03 | 2007-04-24 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
US20050282814A1 (en) * | 2002-10-03 | 2005-12-22 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
CA2567574C (en) * | 2004-04-08 | 2013-01-08 | Targegen, Inc. | Benzotriazine inhibitors of kinases |
NZ553492A (en) * | 2004-08-25 | 2010-11-26 | Targegen Inc | Triazole derivatives and methods of use |
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- 2005-04-07 NZ NZ551027A patent/NZ551027A/en not_active IP Right Cessation
- 2005-04-07 EP EP12167912A patent/EP2543376A1/en not_active Withdrawn
- 2005-04-07 AU AU2005231507A patent/AU2005231507B2/en not_active Ceased
- 2005-04-07 US US11/102,405 patent/US7456176B2/en active Active
- 2005-04-07 KR KR1020067023392A patent/KR20070011458A/ko not_active Application Discontinuation
- 2005-04-07 NZ NZ588139A patent/NZ588139A/en not_active IP Right Cessation
- 2005-04-07 RU RU2006139258/04A patent/RU2006139258A/ru not_active Application Discontinuation
- 2005-04-07 EP EP05762774.7A patent/EP1809614B1/en not_active Not-in-force
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2006
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CA2567574A1 (en) | 2005-10-20 |
US20090275569A1 (en) | 2009-11-05 |
EP1809614A4 (en) | 2010-02-17 |
NZ588139A (en) | 2012-02-24 |
US8481536B2 (en) | 2013-07-09 |
NZ551027A (en) | 2011-01-28 |
RU2006139258A (ru) | 2008-05-20 |
US20110294796A1 (en) | 2011-12-01 |
EP1809614A2 (en) | 2007-07-25 |
EP1809614B1 (en) | 2014-05-07 |
AU2005231507A1 (en) | 2005-10-20 |
HK1110578A1 (en) | 2008-07-18 |
IL178908A (en) | 2015-09-24 |
AU2005231507B2 (en) | 2012-03-01 |
WO2005096784A3 (en) | 2009-02-19 |
WO2005096784A2 (en) | 2005-10-20 |
US20050245524A1 (en) | 2005-11-03 |
EP2543376A1 (en) | 2013-01-09 |
CA2567574C (en) | 2013-01-08 |
IL178908A0 (en) | 2011-08-01 |
US7456176B2 (en) | 2008-11-25 |
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