KR20010101991A - 리포좀 분말 에어로졸의 폐적용을 위한 압축 공기 흡입기및 그에 적합한 분말 에어로졸 - Google Patents

리포좀 분말 에어로졸의 폐적용을 위한 압축 공기 흡입기및 그에 적합한 분말 에어로졸 Download PDF

Info

Publication number
KR20010101991A
KR20010101991A KR1020017009854A KR20017009854A KR20010101991A KR 20010101991 A KR20010101991 A KR 20010101991A KR 1020017009854 A KR1020017009854 A KR 1020017009854A KR 20017009854 A KR20017009854 A KR 20017009854A KR 20010101991 A KR20010101991 A KR 20010101991A
Authority
KR
South Korea
Prior art keywords
compressed air
powder aerosol
liposomes
liposome
aerosol
Prior art date
Application number
KR1020017009854A
Other languages
English (en)
Korean (ko)
Inventor
디에데리흐쥴리아에바
코흐울프강
뢰딩후버트
레스즈카레기나
빈트호르스트
Original Assignee
간덴 데, 죠스트 에.
막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친
슈베르트 헬무트
프라운호퍼-게젤샤프트 츄어 푀르더룽 데어 안게반텐 포르슝에.파우.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 간덴 데, 죠스트 에., 막스-델부뤽-센트럼 퓌어 몰레쿨라레 메디친, 슈베르트 헬무트, 프라운호퍼-게젤샤프트 츄어 푀르더룽 데어 안게반텐 포르슝에.파우. filed Critical 간덴 데, 죠스트 에.
Publication of KR20010101991A publication Critical patent/KR20010101991A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/0012—Apparatus for achieving spraying before discharge from the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/06—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/062—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet
    • B05B7/066—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with only one liquid outlet and at least one gas outlet with an inner liquid outlet surrounded by at least one annular gas outlet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
KR1020017009854A 1999-02-03 2000-02-03 리포좀 분말 에어로졸의 폐적용을 위한 압축 공기 흡입기및 그에 적합한 분말 에어로졸 KR20010101991A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19905285.9 1999-02-03
DE19905285 1999-02-03
DE19954107 1999-11-02
DE19954107.8 1999-11-02
PCT/DE2000/000337 WO2000045878A2 (de) 1999-02-03 2000-02-03 Druckluftinhalator zur pulmonalen applikation liposomalen pulver-aerosols sowie dafür geeignete pulver-aerosole

Publications (1)

Publication Number Publication Date
KR20010101991A true KR20010101991A (ko) 2001-11-15

Family

ID=26051750

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020017009854A KR20010101991A (ko) 1999-02-03 2000-02-03 리포좀 분말 에어로졸의 폐적용을 위한 압축 공기 흡입기및 그에 적합한 분말 에어로졸

Country Status (12)

Country Link
EP (1) EP1148905A2 (ja)
JP (1) JP2002538855A (ja)
KR (1) KR20010101991A (ja)
CN (1) CN1338956A (ja)
AU (1) AU3416400A (ja)
CA (1) CA2361807A1 (ja)
DE (1) DE10004860A1 (ja)
HU (1) HUP0105445A2 (ja)
PL (1) PL349885A1 (ja)
RU (1) RU2001124354A (ja)
SK (1) SK10942001A3 (ja)
WO (1) WO2000045878A2 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100682334B1 (ko) * 2006-07-14 2007-02-16 (주)지에프씨 미립상 레시틴 왁스 조성물 제조장치
KR101313993B1 (ko) * 2012-07-24 2013-10-01 한국화학연구원 약물 흡입 장치
WO2014017826A1 (ko) * 2012-07-24 2014-01-30 한국화학연구원 약물 흡입 장치

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10112167C2 (de) * 2001-03-12 2003-02-13 Bionorica Ag Verfahren zur schonenden Gewinnung von Trockenextrakten
US6900317B2 (en) 2002-02-19 2005-05-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Salts of the CGRP antagonist BIBN4096 and inhalable powdered medicaments containing them
GB0219815D0 (en) * 2002-08-24 2002-10-02 Accentus Plc Preparation of small crystals
US6883517B2 (en) * 2002-09-30 2005-04-26 Asaf Halamish Downdraft nebulizer
US7459146B2 (en) * 2003-05-30 2008-12-02 3M Innovative Properties Company Stabilized aerosol dispersions
WO2005102429A1 (en) 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
JP5674637B2 (ja) * 2009-02-26 2015-02-25 中村　正一 ガスミスト吸入器
RU2595971C2 (ru) 2011-09-06 2016-08-27 Бритиш Америкэн Тобэкко (Инвестментс) Лимитед Нагревание курительного материала
WO2013065776A1 (ja) * 2011-11-04 2013-05-10 日本エー・シー・ピー株式会社 ガスミスト吸入器
GB201217067D0 (en) 2012-09-25 2012-11-07 British American Tobacco Co Heating smokable material
GB201311620D0 (en) 2013-06-28 2013-08-14 British American Tobacco Co Devices Comprising a Heat Source Material and Activation Chambers for the Same
GB201500582D0 (en) 2015-01-14 2015-02-25 British American Tobacco Co Apparatus for heating or cooling a material contained therein
GB201415381D0 (en) * 2014-08-29 2014-10-15 Algipharma As Inhalable powder formulations of alginate oligomers
US11924930B2 (en) 2015-08-31 2024-03-05 Nicoventures Trading Limited Article for use with apparatus for heating smokable material
US20170055584A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Article for use with apparatus for heating smokable material
US20170055575A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Material for use with apparatus for heating smokable material
US20170119047A1 (en) 2015-10-30 2017-05-04 British American Tobacco (Investments) Limited Article for Use with Apparatus for Heating Smokable Material
US20170119046A1 (en) 2015-10-30 2017-05-04 British American Tobacco (Investments) Limited Apparatus for Heating Smokable Material
CN109562237B (zh) * 2016-04-15 2021-08-27 卡尔生物治疗公司 雾化喷嘴和操作这样的雾化喷嘴的方法
GB201817868D0 (en) * 2018-11-01 2018-12-19 Nicoventures Trading Ltd Aerosolised formulation
CN111514418B (zh) * 2019-06-12 2022-01-14 中南大学湘雅二医院 一种自吸式经鼻粉末材料给送装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3569880D1 (de) * 1984-05-28 1989-06-08 Mallinckrodt Inc Aerosol generator-inhalator
US5209821A (en) * 1985-05-09 1993-05-11 Purdue Research Foundation Apparatus for removing volatiles from, or dehydrating, liquid products
DE3686025T2 (de) 1985-05-22 1993-01-07 Liposome Technology Inc Verfahren und system zum einatmen von liposomen.
DE4438292C2 (de) * 1994-10-26 1999-07-22 Pari Gmbh Dosisgenaue Aerosolerzeugung für die Inhalationstherapie
GB2321419B (en) * 1997-01-27 2001-02-07 Medic Aid Ltd Atomizer

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100682334B1 (ko) * 2006-07-14 2007-02-16 (주)지에프씨 미립상 레시틴 왁스 조성물 제조장치
KR101313993B1 (ko) * 2012-07-24 2013-10-01 한국화학연구원 약물 흡입 장치
WO2014017826A1 (ko) * 2012-07-24 2014-01-30 한국화학연구원 약물 흡입 장치
WO2014017827A1 (ko) * 2012-07-24 2014-01-30 한국화학연구원 약물 흡입 장치
KR101373981B1 (ko) * 2012-07-24 2014-03-12 한국화학연구원 약물 흡입 장치

Also Published As

Publication number Publication date
RU2001124354A (ru) 2003-06-20
CA2361807A1 (en) 2000-08-10
WO2000045878A3 (de) 2000-09-28
EP1148905A2 (de) 2001-10-31
SK10942001A3 (sk) 2002-05-09
DE10004860A1 (de) 2000-10-05
PL349885A1 (en) 2002-09-23
AU3416400A (en) 2000-08-25
HUP0105445A2 (en) 2002-06-29
JP2002538855A (ja) 2002-11-19
WO2000045878A2 (de) 2000-08-10
CN1338956A (zh) 2002-03-06

Similar Documents

Publication Publication Date Title
KR20010101991A (ko) 리포좀 분말 에어로졸의 폐적용을 위한 압축 공기 흡입기및 그에 적합한 분말 에어로졸
US20050196345A1 (en) Compressed air inhaler for pulmonary application of liposomal powder aerosols and powder aerosols
JP4766745B2 (ja) 経鼻式吸入器
EP1061901B1 (en) Nicotine inhaler
ES2525087T5 (es) Polvos basados en fosfolípidos para administración de fármacos
KR100652532B1 (ko) 유동 저항이 조절된 에어로졸화 활성 약물의 송달
CA2081474A1 (en) Direct spray-dried drug/lipid powder composition
Javadzadeh et al. Therapeutic nanostructures for pulmonary drug delivery
AU4979700A (en) Compositions for aerosolization and inhalation
JPH11506790A (ja) 肺疾患の治療に有用なジヌクレオチド
JPS63500175A (ja) リポソ−ム吸入法および吸入システム
PT1143931E (pt) Libertação de fármacos por via pulmonar
JP2003528701A (ja) 定量吐出装置および液体配合物
JP2001502666A (ja) 肺遺伝子送達のための組成物および方法
JP3481236B2 (ja) 固体粒状薬剤及び固体粒状薬剤エーロゾル投薬装置
US20200360279A1 (en) Nebulized imatinib formulations, manufacture, and uses thereof
US20020020412A1 (en) Jet nebulizer assembly for home administration of drugs in aerosols
JPS61200849A (ja) リポソームの製造方法
MX2013004030A (es) Composicion farmaceutica a base de denufosol para tratar fibrosis quistica.
CA2265198C (en) Method of producing a nicotine medicament and a medicament made by the method
US20050118108A1 (en) Pulmonary delivery of a liquid medicament aerosol
CZ287114B6 (en) Therapeutic preparation in the form of aerosol and use of gas mixture
CA2329453A1 (en) Helium and neon as means for delivering drug in inhaler
Ho 13. GENERATION AND ANALYSIS OF LIPOSOME AEROSOLS
EP2340816A1 (en) A plant for manufacturing composite carrier particles

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid