KR102803160B1 - sGC 자극제의 고체 형태 - Google Patents
sGC 자극제의 고체 형태 Download PDFInfo
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- KR102803160B1 KR102803160B1 KR1020237017060A KR20237017060A KR102803160B1 KR 102803160 B1 KR102803160 B1 KR 102803160B1 KR 1020237017060 A KR1020237017060 A KR 1020237017060A KR 20237017060 A KR20237017060 A KR 20237017060A KR 102803160 B1 KR102803160 B1 KR 102803160B1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662359466P | 2016-07-07 | 2016-07-07 | |
| US62/359,466 | 2016-07-07 | ||
| KR1020197003464A KR20190025989A (ko) | 2016-07-07 | 2017-07-06 | sGC 자극제의 고체 형태 |
| PCT/US2017/040827 WO2018009609A1 (en) | 2016-07-07 | 2017-07-06 | Solid forms of an sgc stimulator |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197003464A Division KR20190025989A (ko) | 2016-07-07 | 2017-07-06 | sGC 자극제의 고체 형태 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20230074840A KR20230074840A (ko) | 2023-05-31 |
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| KR102803160B1 (ko) | 2016-07-07 | 2025-04-30 | 사이클리온 테라퓨틱스, 인크. | sGC 자극제의 고체 형태 |
| CA3029375A1 (en) | 2016-07-07 | 2018-01-11 | Ironwood Pharmaceuticals, Inc. | Novel processes for preparation of soluble guanylate cyclase stimulators |
| SG10202100168XA (en) | 2016-07-07 | 2021-02-25 | Cyclerion Therapeutics Inc | Novel processes for preparation of soluble guanylate cyclase stimulators |
| WO2019161534A1 (en) * | 2018-02-22 | 2019-08-29 | Ironwood Pharmaceuticals, Inc. | Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators |
| CN109503574B (zh) * | 2018-12-14 | 2021-07-06 | 中国人民解放军军事科学院军事医学研究院 | 抗肺动脉高压药物sgc-003的多晶型晶体变体及其制备方法 |
| CN110862424A (zh) * | 2019-12-03 | 2020-03-06 | 海南顿斯医药科技有限公司 | 一种硫酸阿米卡星化合物 |
| WO2023009710A1 (en) * | 2021-07-28 | 2023-02-02 | Cyclerion Therapeutics, Inc. | Treatment of hfpef in post-menopausal women with an sgc stimulator |
| CN114199812A (zh) * | 2021-12-28 | 2022-03-18 | 南通联亚药业有限公司 | 一种盐酸美金刚缓释制剂中盐酸美金刚的检测方法 |
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2017
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- 2017-07-06 EP EP17739833.6A patent/EP3481820B1/en active Active
- 2017-07-06 MA MA045588A patent/MA45588A/fr unknown
- 2017-07-06 CN CN201780048867.6A patent/CN109563087A/zh active Pending
- 2017-07-06 BR BR112019000293-6A patent/BR112019000293A2/pt not_active Application Discontinuation
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- 2023-06-02 US US18/204,997 patent/US20240059683A1/en not_active Abandoned
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- 2024-08-28 US US18/818,111 patent/US20250129060A1/en not_active Abandoned
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