MX2019000115A - Formas solidas de un estimulador de gualinato ciclasa soluble (sgc). - Google Patents
Formas solidas de un estimulador de gualinato ciclasa soluble (sgc).Info
- Publication number
- MX2019000115A MX2019000115A MX2019000115A MX2019000115A MX2019000115A MX 2019000115 A MX2019000115 A MX 2019000115A MX 2019000115 A MX2019000115 A MX 2019000115A MX 2019000115 A MX2019000115 A MX 2019000115A MX 2019000115 A MX2019000115 A MX 2019000115A
- Authority
- MX
- Mexico
- Prior art keywords
- solid forms
- sgc
- disorders
- sgc stimulator
- stimulator
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 4
- 229940127296 soluble guanylate cyclase stimulator Drugs 0.000 title 1
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 4
- 102000007637 Soluble Guanylyl Cyclase Human genes 0.000 abstract 3
- 108010007205 Soluble Guanylyl Cyclase Proteins 0.000 abstract 3
- ZOOGRGPOEVQQDX-KHLHZJAASA-N cyclic guanosine monophosphate Chemical compound C([C@H]1O2)O[P@](O)(=O)O[C@@H]1[C@H](O)[C@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-KHLHZJAASA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- Tropical Medicine & Parasitology (AREA)
Abstract
La presente descripción se refiere a formas sólidas cristalinas de un estimulador de guanilato ciclasa soluble (sGC), Compuesto I. En la presente descripción también se proporcionan métodos para la preparación de estas formas sólidas. La invención también se refiere a formulaciones farmacéuticas y formas de dosificación que comprenden estas formas sólidas y a usos de estas, solas o en combinación con uno o más agentes adicionales para tratar y/o prevenir diversas enfermedades o trastornos; estas enfermedades o trastornos son aquellos que pueden beneficiarse de la estimulación de sGC o de un aumento en la concentración de óxido nítrico (NO) y/o monofosfato de guanosina cíclica (cGMP).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201662359466P | 2016-07-07 | 2016-07-07 | |
PCT/US2017/040827 WO2018009609A1 (en) | 2016-07-07 | 2017-07-06 | Solid forms of an sgc stimulator |
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MX2019000115A true MX2019000115A (es) | 2019-04-22 |
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MX2019000115A MX2019000115A (es) | 2016-07-07 | 2017-07-06 | Formas solidas de un estimulador de gualinato ciclasa soluble (sgc). |
MX2022001565A MX2022001565A (es) | 2016-07-07 | 2019-01-07 | Formas solidas de un estimulador de guanilato ciclasa soluble (sgc). |
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MX2022001565A MX2022001565A (es) | 2016-07-07 | 2019-01-07 | Formas solidas de un estimulador de guanilato ciclasa soluble (sgc). |
Country Status (16)
Country | Link |
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US (3) | US10889577B2 (es) |
EP (1) | EP3481820B1 (es) |
JP (2) | JP2019524710A (es) |
KR (2) | KR20230074840A (es) |
CN (1) | CN109563087A (es) |
AU (1) | AU2017292818B2 (es) |
BR (1) | BR112019000293A2 (es) |
CA (1) | CA3029333A1 (es) |
CL (1) | CL2019000018A1 (es) |
EA (1) | EA039753B1 (es) |
IL (1) | IL263996B2 (es) |
JO (1) | JOP20180127A1 (es) |
MA (1) | MA45588A (es) |
MX (2) | MX2019000115A (es) |
TW (1) | TWI774683B (es) |
WO (1) | WO2018009609A1 (es) |
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-
2017
- 2017-07-06 EP EP17739833.6A patent/EP3481820B1/en active Active
- 2017-07-06 MX MX2019000115A patent/MX2019000115A/es unknown
- 2017-07-06 WO PCT/US2017/040827 patent/WO2018009609A1/en unknown
- 2017-07-06 JP JP2019500453A patent/JP2019524710A/ja active Pending
- 2017-07-06 KR KR1020237017060A patent/KR20230074840A/ko not_active Application Discontinuation
- 2017-07-06 CA CA3029333A patent/CA3029333A1/en active Pending
- 2017-07-06 EA EA201990235A patent/EA039753B1/ru unknown
- 2017-07-06 AU AU2017292818A patent/AU2017292818B2/en active Active
- 2017-07-06 CN CN201780048867.6A patent/CN109563087A/zh active Pending
- 2017-07-06 BR BR112019000293-6A patent/BR112019000293A2/pt unknown
- 2017-07-06 KR KR1020197003464A patent/KR20190025989A/ko not_active Application Discontinuation
- 2017-07-06 IL IL263996A patent/IL263996B2/en unknown
- 2017-07-06 US US16/315,226 patent/US10889577B2/en active Active
- 2017-07-06 MA MA045588A patent/MA45588A/fr unknown
- 2017-07-07 TW TW106122962A patent/TWI774683B/zh active
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2018
- 2018-12-24 JO JOP/2018/0127A patent/JOP20180127A1/ar unknown
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2019
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- 2019-01-07 MX MX2022001565A patent/MX2022001565A/es unknown
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2020
- 2020-12-29 US US17/136,473 patent/US11572358B2/en active Active
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2022
- 2022-07-04 JP JP2022107994A patent/JP2022130689A/ja active Pending
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2023
- 2023-06-02 US US18/204,997 patent/US20240059683A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
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CN109563087A (zh) | 2019-04-02 |
EA201990235A1 (ru) | 2019-07-31 |
TW201805283A (zh) | 2018-02-16 |
BR112019000293A2 (pt) | 2019-04-16 |
US10889577B2 (en) | 2021-01-12 |
IL263996A (en) | 2019-01-31 |
AU2017292818A1 (en) | 2019-01-31 |
US20190169179A1 (en) | 2019-06-06 |
CA3029333A1 (en) | 2018-01-11 |
IL263996B2 (en) | 2024-03-01 |
EA039753B1 (ru) | 2022-03-10 |
KR20230074840A (ko) | 2023-05-31 |
IL263996B1 (en) | 2023-11-01 |
MX2022001565A (es) | 2022-03-02 |
EP3481820A1 (en) | 2019-05-15 |
KR20190025989A (ko) | 2019-03-12 |
WO2018009609A1 (en) | 2018-01-11 |
CL2019000018A1 (es) | 2019-05-03 |
MA45588A (fr) | 2019-05-15 |
JP2022130689A (ja) | 2022-09-06 |
TWI774683B (zh) | 2022-08-21 |
AU2017292818B2 (en) | 2021-10-21 |
JP2019524710A (ja) | 2019-09-05 |
US20210188830A1 (en) | 2021-06-24 |
US11572358B2 (en) | 2023-02-07 |
US20240059683A1 (en) | 2024-02-22 |
EP3481820B1 (en) | 2023-10-18 |
JOP20180127A1 (ar) | 2019-01-30 |
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