MA45603A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents

Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Info

Publication number
MA45603A
MA45603A MA045603A MA45603A MA45603A MA 45603 A MA45603 A MA 45603A MA 045603 A MA045603 A MA 045603A MA 45603 A MA45603 A MA 45603A MA 45603 A MA45603 A MA 45603A
Authority
MA
Morocco
Prior art keywords
guanylate cyclase
new processes
soluble guanylate
preparing soluble
cyclase stimulators
Prior art date
Application number
MA045603A
Other languages
English (en)
Inventor
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Song Xue
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MA45603A publication Critical patent/MA45603A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA045603A 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble MA45603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07

Publications (1)

Publication Number Publication Date
MA45603A true MA45603A (fr) 2019-05-15

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045603A MA45603A (fr) 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Country Status (16)

Country Link
US (3) US11319308B2 (fr)
EP (2) EP4249488A3 (fr)
JP (1) JP7112384B2 (fr)
KR (1) KR102487872B1 (fr)
CN (1) CN109563077A (fr)
AU (1) AU2017291827B2 (fr)
BR (1) BR112019000291A2 (fr)
CA (1) CA3029375A1 (fr)
CL (2) CL2019000016A1 (fr)
EA (1) EA201990237A1 (fr)
ES (1) ES2963563T3 (fr)
IL (1) IL263995B (fr)
MA (1) MA45603A (fr)
MX (2) MX2019000105A (fr)
SG (1) SG11201900096QA (fr)
WO (1) WO2018009597A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7054395B2 (ja) * 2016-07-07 2022-04-13 サイクレリオン・セラピューティクス,インコーポレーテッド 可溶性グアニル酸シクラーゼ刺激剤の新規な調製方法
CN109563077A (zh) 2016-07-07 2019-04-02 铁木医药有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的新方法
TW202402741A (zh) 2018-01-10 2024-01-16 美商賽克瑞恩醫療公司 用於製備可溶性鳥苷酸環化酶刺激劑之新穎方法及中間物
WO2019161534A1 (fr) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ603789A (en) 2010-05-26 2015-03-27 Sunovion Pharmaceuticals Inc Heteroaryl compounds and methods of use thereof
DK2588465T3 (en) 2010-06-30 2017-05-01 Ironwood Pharmaceuticals Inc SGC stimulators
CA2861804C (fr) * 2011-12-27 2021-10-26 Ironwood Pharmaceuticals, Inc. Pyrazoles 2-benzyle, 3-(pyrimidin-2-yle)-substitues utiles comme stimulateurs de scg
CA2885645A1 (fr) * 2012-09-19 2014-03-27 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
CN109369635B (zh) * 2013-03-15 2023-06-30 赛克里翁治疗有限公司 化合物或其药学上可接受的盐及其应用和药物组合物
US20160311826A1 (en) * 2013-12-11 2016-10-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
US20170298055A1 (en) * 2014-09-17 2017-10-19 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
EP3194386A2 (fr) * 2014-09-17 2017-07-26 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
US20170291889A1 (en) * 2014-09-17 2017-10-12 Ironwood Pharmaceuticals, Inc. Pyrazole derivatives as sgc stimulators
CA2961531A1 (fr) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Stimulateurs de la sgc
KR20180086497A (ko) * 2015-11-30 2018-07-31 아이언우드 파마슈티컬스, 인코포레이티드 sGC 자극제를 포함하는 고체 분산물
CN109563077A (zh) 2016-07-07 2019-04-02 铁木医药有限公司 用于制备可溶性鸟苷酸环化酶刺激剂的新方法
JP7054395B2 (ja) 2016-07-07 2022-04-13 サイクレリオン・セラピューティクス,インコーポレーテッド 可溶性グアニル酸シクラーゼ刺激剤の新規な調製方法
US10889577B2 (en) 2016-07-07 2021-01-12 Cyclerion Therapeutics, Inc. Solid forms of an sGC stimulator
US11897887B2 (en) * 2017-12-19 2024-02-13 Tisento Therapeutics Inc. sGC stimulators
TW202402741A (zh) * 2018-01-10 2024-01-16 美商賽克瑞恩醫療公司 用於製備可溶性鳥苷酸環化酶刺激劑之新穎方法及中間物

Also Published As

Publication number Publication date
CA3029375A1 (fr) 2018-01-11
US20210323951A1 (en) 2021-10-21
US20240059684A1 (en) 2024-02-22
US11319308B2 (en) 2022-05-03
CN109563077A (zh) 2019-04-02
BR112019000291A2 (pt) 2019-04-16
MX2019000105A (es) 2019-04-22
JP2019525913A (ja) 2019-09-12
KR20190025986A (ko) 2019-03-12
AU2017291827A1 (en) 2019-02-07
EP3481818A1 (fr) 2019-05-15
AU2017291827B2 (en) 2021-10-21
EP3481818C0 (fr) 2023-09-06
EP4249488A2 (fr) 2023-09-27
KR102487872B1 (ko) 2023-01-12
MX2022001495A (es) 2022-03-11
US20220227748A1 (en) 2022-07-21
CL2019000016A1 (es) 2019-05-03
EP4249488A3 (fr) 2023-12-20
EA201990237A1 (ru) 2019-08-30
CL2023000228A1 (es) 2023-09-29
JP7112384B2 (ja) 2022-08-03
IL263995B (en) 2021-02-28
EP3481818B1 (fr) 2023-09-06
SG11201900096QA (en) 2019-02-27
ES2963563T3 (es) 2024-03-27
US11773089B2 (en) 2023-10-03
WO2018009597A1 (fr) 2018-01-11
IL263995A (en) 2019-02-28

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