MA45603A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents

Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Info

Publication number
MA45603A
MA45603A MA045603A MA45603A MA45603A MA 45603 A MA45603 A MA 45603A MA 045603 A MA045603 A MA 045603A MA 45603 A MA45603 A MA 45603A MA 45603 A MA45603 A MA 45603A
Authority
MA
Morocco
Prior art keywords
guanylate cyclase
new processes
soluble guanylate
preparing soluble
cyclase stimulators
Prior art date
Application number
MA045603A
Other languages
English (en)
Inventor
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Song Xue
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MA45603A publication Critical patent/MA45603A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA045603A 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble MA45603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07

Publications (1)

Publication Number Publication Date
MA45603A true MA45603A (fr) 2019-05-15

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045603A MA45603A (fr) 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Country Status (16)

Country Link
US (3) US11319308B2 (fr)
EP (2) EP4249488A3 (fr)
JP (1) JP7112384B2 (fr)
KR (1) KR102487872B1 (fr)
CN (1) CN109563077A (fr)
AU (1) AU2017291827B2 (fr)
BR (1) BR112019000291A2 (fr)
CA (1) CA3029375A1 (fr)
CL (2) CL2019000016A1 (fr)
EA (1) EA201990237A1 (fr)
ES (1) ES2963563T3 (fr)
IL (1) IL263995B (fr)
MA (1) MA45603A (fr)
MX (2) MX2019000105A (fr)
SG (1) SG11201900096QA (fr)
WO (1) WO2018009597A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
MA45603A (fr) 2016-07-07 2019-05-15 Ironwood Pharmaceuticals Inc Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble
SG11202006311SA (en) 2018-01-10 2020-07-29 Cyclerion Therapeutics Inc Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators
WO2019161534A1 (fr) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8969349B2 (en) 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors
WO2012003405A1 (fr) 2010-06-30 2012-01-05 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
EP2797915B1 (fr) * 2011-12-27 2016-07-13 Ironwood Pharmaceuticals, Inc. Dérivés de 2-bénzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole en tant que stimulateurs de la cyclase de guanylate soluble (sGC) pour le traitement de la hypertension ou de l'insuffisance cardiaque
EP2897953B8 (fr) * 2012-09-19 2019-06-26 Cyclerion Therapeutics, Inc. Stimulateurs de sgc
SI3660013T1 (sl) * 2013-03-15 2022-05-31 Cyclerion Therapeutics, Inc. SGC stimulatorji
EP3092231B1 (fr) 2013-12-11 2018-06-27 Ironwood Pharmaceuticals, Inc. Stimulateurs de la sgc
EP3194382B1 (fr) * 2014-09-17 2021-09-08 Cyclerion Therapeutics, Inc. Dérivés de pyrazole utilisés comme stimulateurs de sgc
JP2017527604A (ja) * 2014-09-17 2017-09-21 アイアンウッド ファーマシューティカルズ インコーポレイテッド sGC刺激剤
EP3194395B1 (fr) * 2014-09-17 2019-12-04 Cyclerion Therapeutics, Inc. Stimulateurs de la sgc
WO2016044445A2 (fr) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Stimulateurs de sgc
EA201891315A1 (ru) 2015-11-30 2018-12-28 Айронвуд Фармасьютикалз, Инк. Твердые дисперсии, содержащие стимулятор sgc
EP3481820B1 (fr) 2016-07-07 2023-10-18 Cyclerion Therapeutics, Inc. Formes solides d'un stimulateur de la gcs
MA45603A (fr) 2016-07-07 2019-05-15 Ironwood Pharmaceuticals Inc Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
CA3086207A1 (fr) * 2017-12-19 2019-06-27 Cyclerion Therapeutics, Inc. Stimulateurs de sgc
SG11202006311SA (en) * 2018-01-10 2020-07-29 Cyclerion Therapeutics Inc Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators

Also Published As

Publication number Publication date
US20220227748A1 (en) 2022-07-21
EP3481818B1 (fr) 2023-09-06
WO2018009597A1 (fr) 2018-01-11
EP4249488A2 (fr) 2023-09-27
EA201990237A1 (ru) 2019-08-30
EP4249488A3 (fr) 2023-12-20
EP3481818C0 (fr) 2023-09-06
BR112019000291A2 (pt) 2019-04-16
SG11201900096QA (en) 2019-02-27
US11773089B2 (en) 2023-10-03
CN109563077A (zh) 2019-04-02
KR20190025986A (ko) 2019-03-12
CL2023000228A1 (es) 2023-09-29
CL2019000016A1 (es) 2019-05-03
EP3481818A1 (fr) 2019-05-15
US20240059684A1 (en) 2024-02-22
ES2963563T3 (es) 2024-03-27
JP2019525913A (ja) 2019-09-12
MX2019000105A (es) 2019-04-22
KR102487872B1 (ko) 2023-01-12
IL263995A (en) 2019-02-28
IL263995B (en) 2021-02-28
US20210323951A1 (en) 2021-10-21
CA3029375A1 (fr) 2018-01-11
MX2022001495A (es) 2022-03-11
AU2017291827B2 (en) 2021-10-21
US11319308B2 (en) 2022-05-03
AU2017291827A1 (en) 2019-02-07
JP7112384B2 (ja) 2022-08-03

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