MA45593A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents
Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase solubleInfo
- Publication number
- MA45593A MA45593A MA045593A MA45593A MA45593A MA 45593 A MA45593 A MA 45593A MA 045593 A MA045593 A MA 045593A MA 45593 A MA45593 A MA 45593A MA 45593 A MA45593 A MA 45593A
- Authority
- MA
- Morocco
- Prior art keywords
- guanylate cyclase
- new processes
- soluble guanylate
- preparing soluble
- cyclase stimulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662359430P | 2016-07-07 | 2016-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA45593A true MA45593A (fr) | 2019-05-15 |
Family
ID=59351140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA045593A MA45593A (fr) | 2016-07-07 | 2017-07-06 | Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US11834444B2 (fr) |
| EP (1) | EP3481821B1 (fr) |
| JP (1) | JP7054395B2 (fr) |
| KR (1) | KR102513357B1 (fr) |
| CN (1) | CN109563086B (fr) |
| AU (1) | AU2017292811B2 (fr) |
| BR (1) | BR112019000292A2 (fr) |
| CA (1) | CA3029376A1 (fr) |
| CL (1) | CL2019000017A1 (fr) |
| EA (1) | EA201990236A1 (fr) |
| ES (1) | ES2962829T3 (fr) |
| IL (1) | IL263994B (fr) |
| JO (1) | JOP20180126A1 (fr) |
| MA (1) | MA45593A (fr) |
| MX (1) | MX2019000138A (fr) |
| SG (2) | SG11201900125PA (fr) |
| WO (1) | WO2018009602A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201900096QA (en) * | 2016-07-07 | 2019-02-27 | Ironwood Pharmaceuticals Inc | Novel processes for preparation of soluble guanylate cyclase stimulators |
| WO2019161534A1 (fr) * | 2018-02-22 | 2019-08-29 | Ironwood Pharmaceuticals, Inc. | Nouveaux procédés et intermédiaires pour la préparation de stimulateurs de guanylate cyclase soluble |
| MX2020007364A (es) | 2018-01-10 | 2020-11-18 | Cyclerion Therapeutics Inc | Nuevos procesos e intermediarios para la preparación de estimulantes de guanilato ciclasa soluble. |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101955439A (zh) * | 2009-07-14 | 2011-01-26 | 华东理工大学 | 一种α-取代-2-氨基乙酰胺的拆分方法 |
| AR088020A1 (es) | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | Compuestos heterociclicos como estimuladores de sgc |
| AU2012206561B2 (en) * | 2011-01-13 | 2015-12-17 | Novartis Ag | Novel heterocyclic derivatives and their use in the treatment of neurological disorders |
| CA2861804C (fr) | 2011-12-27 | 2021-10-26 | Ironwood Pharmaceuticals, Inc. | Pyrazoles 2-benzyle, 3-(pyrimidin-2-yle)-substitues utiles comme stimulateurs de scg |
| EP3660013B1 (fr) | 2013-03-15 | 2022-01-19 | Cyclerion Therapeutics, Inc. | Stimulateurs de sgc |
| CA2959757A1 (fr) * | 2014-09-17 | 2016-03-24 | Ironwood Pharmaceuticals, Inc. | Derives de pyrazole utilises comme stimulateurs de sgc |
| CN116637076A (zh) | 2015-11-30 | 2023-08-25 | 赛克里翁治疗有限公司 | 包含sGC刺激剂的固体分散体 |
| IL263996B2 (en) | 2016-07-07 | 2024-03-01 | Ironwood Pharmaceuticals Inc | Solid configurations of the SGC promoter |
| SG11201900096QA (en) * | 2016-07-07 | 2019-02-27 | Ironwood Pharmaceuticals Inc | Novel processes for preparation of soluble guanylate cyclase stimulators |
-
2017
- 2017-07-06 KR KR1020197003461A patent/KR102513357B1/ko active IP Right Grant
- 2017-07-06 CN CN201780048199.7A patent/CN109563086B/zh active Active
- 2017-07-06 US US16/315,221 patent/US11834444B2/en active Active
- 2017-07-06 SG SG11201900125PA patent/SG11201900125PA/en unknown
- 2017-07-06 WO PCT/US2017/040817 patent/WO2018009602A2/fr unknown
- 2017-07-06 EP EP17740238.5A patent/EP3481821B1/fr active Active
- 2017-07-06 MX MX2019000138A patent/MX2019000138A/es unknown
- 2017-07-06 MA MA045593A patent/MA45593A/fr unknown
- 2017-07-06 AU AU2017292811A patent/AU2017292811B2/en active Active
- 2017-07-06 JP JP2019500469A patent/JP7054395B2/ja active Active
- 2017-07-06 EA EA201990236A patent/EA201990236A1/ru unknown
- 2017-07-06 ES ES17740238T patent/ES2962829T3/es active Active
- 2017-07-06 BR BR112019000292-8A patent/BR112019000292A2/pt active Search and Examination
- 2017-07-06 CA CA3029376A patent/CA3029376A1/fr active Pending
- 2017-07-06 SG SG10202100168XA patent/SG10202100168XA/en unknown
-
2018
- 2018-12-24 JO JOP/2018/0126A patent/JOP20180126A1/ar unknown
- 2018-12-27 IL IL263994A patent/IL263994B/en unknown
-
2019
- 2019-01-04 CL CL2019000017A patent/CL2019000017A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2019000138A (es) | 2019-06-10 |
| SG11201900125PA (en) | 2019-02-27 |
| EP3481821A2 (fr) | 2019-05-15 |
| US11834444B2 (en) | 2023-12-05 |
| AU2017292811B2 (en) | 2021-10-21 |
| IL263994A (en) | 2019-01-31 |
| CA3029376A1 (fr) | 2018-01-11 |
| AU2017292811A1 (en) | 2019-02-07 |
| EP3481821C0 (fr) | 2023-09-06 |
| WO2018009602A2 (fr) | 2018-01-11 |
| EP3481821B1 (fr) | 2023-09-06 |
| US20210284632A1 (en) | 2021-09-16 |
| JOP20180126A1 (ar) | 2019-01-30 |
| KR102513357B1 (ko) | 2023-03-24 |
| EA201990236A1 (ru) | 2019-08-30 |
| CL2019000017A1 (es) | 2019-05-03 |
| KR20190025987A (ko) | 2019-03-12 |
| ES2962829T3 (es) | 2024-03-21 |
| SG10202100168XA (en) | 2021-02-25 |
| JP2019524712A (ja) | 2019-09-05 |
| CN109563086B (zh) | 2023-05-23 |
| CN109563086A (zh) | 2019-04-02 |
| JP7054395B2 (ja) | 2022-04-13 |
| BR112019000292A2 (pt) | 2019-04-16 |
| IL263994B (en) | 2021-10-31 |
| WO2018009602A3 (fr) | 2018-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1257760A1 (zh) | 多特異性抗體 | |
| ZA201700737B (en) | Cyclohexyl-ethyl substituted diaza- and triaza-tricyclic compounds as indole-amine-2,3-dioxygenase (ido) antagonists for the treatment of cancer | |
| HK1251546A1 (zh) | S-氯胺酮的(s)-csa鹽、s-氯胺酮的(r)-csa鹽和用於製備s-氯胺酮的方法 | |
| IL264143B (en) | Processes for preparing olaparib | |
| SI3433285T1 (sl) | Izboljšan postopek za pripravo sugamadeksa | |
| MA55193A (fr) | Procédés de préparation d'un inhibiteur de pi3k | |
| EP3152214A4 (fr) | Dérivés d'imidazo-pyrazine utiles en tant qu'activateurs de guanylate cyclases solubles | |
| DK3475417T3 (da) | Sammensætninger og fremgangsmåder til fremstilling af benzylisoquinolin-alkaloider, morphinan-alkaloider, thebain og derivater deraf | |
| EP3310782A4 (fr) | Dérivés d'imidazo-pyrazinyle utiles à titre d'activateurs de guanylate cyclase solubles | |
| EP3303342A4 (fr) | Dérivés d'imidazo-pyrazinyle utiles à titre d'activateurs de guanylate cyclase solubles | |
| MA45154A (fr) | Procédés de préparation d'oligomères | |
| MA45603A (fr) | Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble | |
| IL260465B (en) | A process for preparing an antibody-rifamycin conjugate | |
| IL260011A (en) | History of 5,3-diphenyl-diazole water-soluble compounds | |
| MA45593A (fr) | Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble | |
| EP3296287A4 (fr) | Procédé de purification de 1,4-diaminobutane | |
| PL3228619T3 (pl) | Sposób wytwarzania apiksabanu | |
| EP3305255A4 (fr) | Ceinture de grossesse de type gilet | |
| GB2561089B (en) | Process for the preparation of 17beta-hydroxy-des-a-androst-9, 10-en-5-one | |
| IL276852A (en) | A process for making soluble guinelate cyclase beads | |
| ZA201701533B (en) | Improvements to router apparatus (base features) | |
| IL251229A0 (en) | Process for preparing 5-bromo-1,2,3-trichlorobenzene | |
| MA45184A (fr) | Procédé de préparation de l'éluxadoline . | |
| IL253630A0 (en) | A process for the preparation of modified phenylisoxazoline derivatives | |
| GB2544346B (en) | Apparatus for tree work |