KR102645398B1 - 신규 인공 핵산 분자 - Google Patents
신규 인공 핵산 분자 Download PDFInfo
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- KR102645398B1 KR102645398B1 KR1020187008732A KR20187008732A KR102645398B1 KR 102645398 B1 KR102645398 B1 KR 102645398B1 KR 1020187008732 A KR1020187008732 A KR 1020187008732A KR 20187008732 A KR20187008732 A KR 20187008732A KR 102645398 B1 KR102645398 B1 KR 102645398B1
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| KR20240111764A (ko) * | 2021-12-13 | 2024-07-17 | 주식회사 에스엠엘바이오팜 | 발현 효율을 증가시킨 핵산 발현 플랫폼 |
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| WO2012116714A1 (en) | 2011-03-02 | 2012-09-07 | Curevac Gmbh | Vaccination in elderly patients |
| WO2013120497A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein |
| WO2013120499A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen |
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| WO2015024668A2 (en) | 2013-08-21 | 2015-02-26 | Curevac Gmbh | Respiratory syncytial virus (rsv) vaccine |
| WO2015024669A1 (en) | 2013-08-21 | 2015-02-26 | Curevac Gmbh | Combination vaccine |
| RU2712743C2 (ru) | 2013-08-21 | 2020-01-30 | Куревак Аг | Вакцина против бешенства |
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| PT3766916T (pt) | 2014-06-25 | 2022-11-28 | Acuitas Therapeutics Inc | Novos lípidos e formulações de nanopartículas lipídicas para distribuição de ácidos nucleicos |
| DK3708668T3 (da) | 2014-12-12 | 2022-09-26 | Curevac Ag | Kunstigt nukleinsyremolekyle til forbedret proteinudtrykkelse |
| EP3283059B1 (en) | 2015-04-13 | 2024-01-03 | CureVac Manufacturing GmbH | Method for producing rna compositions |
| EP4026568A1 (en) | 2015-04-17 | 2022-07-13 | CureVac Real Estate GmbH | Lyophilization of rna |
| US20180303925A1 (en) | 2015-04-27 | 2018-10-25 | The Trustees Of The University Of Pennsylvania | Nucleoside-Modified RNA For Inducing an Adaptive Immune Response |
| EP3289101B1 (en) | 2015-04-30 | 2021-06-23 | CureVac AG | Immobilized poly(n)polymerase |
| EP3294885B1 (en) | 2015-05-08 | 2020-07-01 | CureVac Real Estate GmbH | Method for producing rna |
| BR112017017949A2 (pt) | 2015-05-15 | 2018-04-10 | Curevac Ag | regimes de iniciação-reforço envolvendo administração de pelo menos um constructo de mrna |
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| EP3298142B1 (en) | 2015-05-20 | 2021-07-14 | CureVac AG | Dry powder composition comprising long-chain rna |
| DK4108769T3 (da) | 2015-05-29 | 2023-10-09 | Curevac Mfg Gmbh | Fremgangsmåde til fremstilling og oprensning af rna, omfattende mindst et trin til tangential-flow-filtrering |
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| AU2016285852B2 (en) | 2015-06-29 | 2020-12-17 | Acuitas Therapeutics Inc. | Lipids and lipid nanoparticle formulations for delivery of nucleic acids |
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| US11225682B2 (en) | 2015-10-12 | 2022-01-18 | Curevac Ag | Automated method for isolation, selection and/or detection of microorganisms or cells comprised in a solution |
| LT3368507T (lt) | 2015-10-28 | 2023-03-10 | Acuitas Therapeutics Inc. | Nauji lipidai ir lipidų nanodalelių kompozicijos, skirtos nukleorūgščių tiekimui |
| US11413346B2 (en) | 2015-11-09 | 2022-08-16 | Curevac Ag | Rotavirus vaccines |
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| CN109475640B (zh) | 2016-06-09 | 2023-03-10 | 库瑞瓦格欧洲公司 | 核酸被运载物的混合载运体 |
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| US12491261B2 (en) | 2016-10-26 | 2025-12-09 | Acuitas Therapeutics, Inc. | Lipid nanoparticle formulations |
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| US20190024096A1 (en) | 2015-08-07 | 2019-01-24 | Curevac Ag | Process for the in vivo production of rna in a host cell |
| EP3334828B1 (en) | 2015-08-10 | 2020-10-28 | CureVac Real Estate GmbH | Method of increasing the replication of a circular dna molecule |
| US11225682B2 (en) | 2015-10-12 | 2022-01-18 | Curevac Ag | Automated method for isolation, selection and/or detection of microorganisms or cells comprised in a solution |
| US11413346B2 (en) | 2015-11-09 | 2022-08-16 | Curevac Ag | Rotavirus vaccines |
| US20180126003A1 (en) | 2016-05-04 | 2018-05-10 | Curevac Ag | New targets for rna therapeutics |
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2016
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| WO2014164253A1 (en) | 2013-03-09 | 2014-10-09 | Moderna Therapeutics, Inc. | Heterologous untranslated regions for mrna |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240111764A (ko) * | 2021-12-13 | 2024-07-17 | 주식회사 에스엠엘바이오팜 | 발현 효율을 증가시킨 핵산 발현 플랫폼 |
| KR102818855B1 (ko) | 2021-12-13 | 2025-06-16 | 주식회사 에스엠엘바이오팜 | 발현 효율을 증가시킨 핵산 발현 플랫폼 |
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| SG10201913629VA (en) | 2020-03-30 |
| JP7304155B2 (ja) | 2023-07-06 |
| CN114381470A (zh) | 2022-04-22 |
| EP4108774A1 (en) | 2022-12-28 |
| JP2021192613A (ja) | 2021-12-23 |
| WO2017036580A1 (en) | 2017-03-09 |
| CN108026537B (zh) | 2022-02-08 |
| DK3341482T3 (da) | 2022-08-15 |
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| MX2018001040A (es) | 2018-06-15 |
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| AU2016316439B2 (en) | 2022-02-24 |
| CA2992801A1 (en) | 2017-03-09 |
| AU2016316439A1 (en) | 2018-02-08 |
| RU2018110872A3 (enExample) | 2020-07-24 |
| EP3341482B1 (en) | 2022-07-06 |
| RU2018110872A (ru) | 2019-10-01 |
| MX395421B (es) | 2025-03-25 |
| KR20180038564A (ko) | 2018-04-16 |
| JP2018529329A (ja) | 2018-10-11 |
| JP7245878B2 (ja) | 2023-03-24 |
| US20250171789A1 (en) | 2025-05-29 |
| BR112018001995A2 (pt) | 2018-09-18 |
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