KR102234623B1 - Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법 - Google Patents

Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법 Download PDF

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KR102234623B1
KR102234623B1 KR1020157035878A KR20157035878A KR102234623B1 KR 102234623 B1 KR102234623 B1 KR 102234623B1 KR 1020157035878 A KR1020157035878 A KR 1020157035878A KR 20157035878 A KR20157035878 A KR 20157035878A KR 102234623 B1 KR102234623 B1 KR 102234623B1
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nucleotides
double
delete delete
rnai agent
strand
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KR20160009687A (ko
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제임스 버틀러
브라이언 베텐코트
칼란토타틸 지. 라지브
마틴 마이어
클라우스 채리스
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알닐람 파마슈티칼스 인코포레이티드
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
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KR1020157035878A 2013-05-22 2014-05-22 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법 Active KR102234623B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217008872A KR102365809B1 (ko) 2013-05-22 2014-05-22 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361826178P 2013-05-22 2013-05-22
US61/826,178 2013-05-22
US201361912988P 2013-12-06 2013-12-06
US61/912,988 2013-12-06
PCT/US2014/039149 WO2014190157A1 (en) 2013-05-22 2014-05-22 Tmprss6 compositions and methods of use thereof

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KR20160009687A KR20160009687A (ko) 2016-01-26
KR102234623B1 true KR102234623B1 (ko) 2021-04-02

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KR1020157035878A Active KR102234623B1 (ko) 2013-05-22 2014-05-22 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법
KR1020227005177A Active KR102486617B1 (ko) 2013-05-22 2014-05-22 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법

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US (6) US9783806B2 (enExample)
EP (3) EP3587578A1 (enExample)
JP (5) JP2016520593A (enExample)
KR (3) KR102365809B1 (enExample)
CN (2) CN105452463B (enExample)
AP (1) AP2015008862A0 (enExample)
AU (3) AU2014268529C1 (enExample)
BR (1) BR112015029276B1 (enExample)
CA (2) CA3178370A1 (enExample)
CL (2) CL2015003440A1 (enExample)
EA (1) EA201592225A1 (enExample)
HK (1) HK1221978A1 (enExample)
IL (5) IL285780B (enExample)
MY (1) MY181888A (enExample)
RU (1) RU2015154738A (enExample)
SG (2) SG10202103166XA (enExample)
TW (3) TWI727917B (enExample)
UY (1) UY35583A (enExample)
WO (1) WO2014190157A1 (enExample)
ZA (1) ZA202110854B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240002200A (ko) * 2022-06-24 2024-01-04 노보 노르디스크 에이/에스 막관통 세린 프로테아제 6(tmprss6) 발현을 억제하기 위한 조성물 및 방법

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013529907A (ja) 2010-05-24 2013-07-25 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク Ｎｇａｌタンパク質変異体及びその使用
SG10201602369PA (en) 2011-03-29 2016-05-30 Alnylam Pharmaceuticals Inc Double-Stranded RNA (dsRNA) For Inhibiting Expression Of TMPRSS6
KR102853694B1 (ko) 2011-11-18 2025-09-03 알닐람 파마슈티칼스 인코포레이티드 변형된 ＲＮＡｉ 제제
EP2925337B1 (en) * 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
KR102365809B1 (ko) 2013-05-22 2022-02-23 알닐람 파마슈티칼스 인코포레이티드 Ｔｍｐｒｓｓ6 조성물 및 이의 사용 방법
CN105899663B (zh) 2013-12-26 2019-07-26 学校法人东京医科大学 用于基因表达控制的人工模拟miRNA及其用途
CN106068324B (zh) 2013-12-27 2020-12-29 株式会社博纳克 控制基因表达的人工匹配型miRNA及其用途
IL316808A (en) 2014-08-20 2025-01-01 Alnylam Pharmaceuticals Inc Modified double-stranded RNA materials and their uses
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