KR102162400B1 - 생체 투여 가능한 수용액 및 그 제조 방법 - Google Patents

생체 투여 가능한 수용액 및 그 제조 방법 Download PDF

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KR102162400B1
KR102162400B1 KR1020187032677A KR20187032677A KR102162400B1 KR 102162400 B1 KR102162400 B1 KR 102162400B1 KR 1020187032677 A KR1020187032677 A KR 1020187032677A KR 20187032677 A KR20187032677 A KR 20187032677A KR 102162400 B1 KR102162400 B1 KR 102162400B1
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aqueous solution
oxygen
nanobubbles
bio
liquid
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KR1020187032677A
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Korean (ko)
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KR20180130568A (ko
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다이 야마노우치
요시아키 다치바나
고스케 다치바나
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시그마 테크놀로지 유겐가이샤
다이 야마노우치
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020187032677A 2016-05-13 2017-05-11 생체 투여 가능한 수용액 및 그 제조 방법 KR102162400B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016096775 2016-05-13
JPJP-P-2016-096775 2016-05-13
PCT/JP2017/017779 WO2017195852A1 (ja) 2016-05-13 2017-05-11 生体投与可能な水溶液及びその製造方法

Publications (2)

Publication Number Publication Date
KR20180130568A KR20180130568A (ko) 2018-12-07
KR102162400B1 true KR102162400B1 (ko) 2020-10-06

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KR1020187032677A KR102162400B1 (ko) 2016-05-13 2017-05-11 생체 투여 가능한 수용액 및 그 제조 방법

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US (2) US20190298653A1 (zh)
EP (1) EP3456815A4 (zh)
JP (1) JP6751876B2 (zh)
KR (1) KR102162400B1 (zh)
CN (1) CN109415686B (zh)
WO (1) WO2017195852A1 (zh)

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US20200197318A1 (en) * 2017-05-22 2020-06-25 The Regents Of The University Of California Micro/nanobubble solutions for tissue preservation and generation thereof
JP2019104688A (ja) * 2017-12-08 2019-06-27 大平 猛 治療方法
JP7227694B2 (ja) * 2017-12-08 2023-02-22 大平 猛 正に帯電したナノバブル分散液
CA3086501C (en) * 2017-12-21 2023-08-22 Siemens Healthcare Diagnostics Inc. Compositions comprising stabilized oxygen and methods of forming the same
JP2019203047A (ja) * 2018-05-21 2019-11-28 豊国石油株式会社 工業用油剤及び工業用油剤の製造方法
EP3843673A4 (en) * 2018-08-31 2022-06-15 Revalesio Corporation METHODS AND COMPOSITIONS FOR THE TREATMENT OF STROKE
JP6760630B1 (ja) * 2019-10-29 2020-09-23 学校法人 愛知医科大学 微小気泡含有電解質液の製造方法および微小気泡含有電解質液の調製に用いる微小気泡含有溶媒の製造方法
EP4065472A1 (en) 2019-11-25 2022-10-05 DEKA Products Limited Partnership System for producing and packaging fluid, sealing member dispenser, reservoir feeding apparatus, bag sealing apparatus, reservoir filling set, method for filling a reservoir or a bag, filling and sampling nozzle
CN114469758B (zh) * 2022-01-25 2024-02-20 中国科学院上海应用物理研究所 一种小粒径纳米气泡水及其制备方法以及应用

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JP2011001271A (ja) * 2009-06-16 2011-01-06 Tomio Ota 輸液
JP2013166143A (ja) * 2012-01-18 2013-08-29 Sigma Technology Kk マイクロ・ナノバブルの発生方法、発生ノズル及び発生装置
US20150343399A1 (en) 2012-12-04 2015-12-03 Chung-Ang University Industry-Academy Cooperation Foundation Device for producing microbubble water by using ultrasonic vibrator, cell culture medium containing microbubble water, cell culturing method using same, high efficiency mixed fuel using microbubbles, and method for manufacturing same

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KR100583430B1 (ko) * 2004-03-08 2006-05-24 양경숙 차륜 가변형 스쿠터
JP5120998B2 (ja) * 2006-09-06 2013-01-16 国立大学法人 東京医科歯科大学 組織、細胞又は臓器の保存液
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CN111729523B (zh) * 2020-06-16 2022-03-15 上海交通大学 一种粒径均一可控的纳米气泡产生方法
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JP2009084258A (ja) * 2007-10-01 2009-04-23 Tokyo Medical & Dental Univ ナノバブルを含む癌の治療又は予防のための薬剤
JP2011001271A (ja) * 2009-06-16 2011-01-06 Tomio Ota 輸液
JP2013166143A (ja) * 2012-01-18 2013-08-29 Sigma Technology Kk マイクロ・ナノバブルの発生方法、発生ノズル及び発生装置
US20150343399A1 (en) 2012-12-04 2015-12-03 Chung-Ang University Industry-Academy Cooperation Foundation Device for producing microbubble water by using ultrasonic vibrator, cell culture medium containing microbubble water, cell culturing method using same, high efficiency mixed fuel using microbubbles, and method for manufacturing same

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Publication number Publication date
JP6751876B2 (ja) 2020-09-09
JPWO2017195852A1 (ja) 2018-07-26
KR20180130568A (ko) 2018-12-07
EP3456815A4 (en) 2019-11-27
EP3456815A1 (en) 2019-03-20
CN109415686A (zh) 2019-03-01
US20190298653A1 (en) 2019-10-03
CN109415686B (zh) 2023-02-21
WO2017195852A1 (ja) 2017-11-16
US20200338000A1 (en) 2020-10-29

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