KR102148303B1 - R-스폰딘 전위 및 그의 사용 방법 - Google Patents

R-스폰딘 전위 및 그의 사용 방법 Download PDF

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KR102148303B1
KR102148303B1 KR1020147024749A KR20147024749A KR102148303B1 KR 102148303 B1 KR102148303 B1 KR 102148303B1 KR 1020147024749 A KR1020147024749 A KR 1020147024749A KR 20147024749 A KR20147024749 A KR 20147024749A KR 102148303 B1 KR102148303 B1 KR 102148303B1
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exon
translocation
spondin
rspo3
rspo2
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KR20140130461A (ko
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조라 모드루산
프레데릭 제이. 드사우바게
스테펜 두린크
소마세카르 세샤기리
에릭 윌리엄 스타위스키
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제넨테크, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
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  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020147024749A 2012-02-11 2013-02-11 R-스폰딘 전위 및 그의 사용 방법 Expired - Fee Related KR102148303B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261597746P 2012-02-11 2012-02-11
US61/597,746 2012-02-11
US201261674763P 2012-07-23 2012-07-23
US61/674,763 2012-07-23
PCT/US2013/025525 WO2013120056A1 (en) 2012-02-11 2013-02-11 R-spondin translocations and methods using the same

Publications (2)

Publication Number Publication Date
KR20140130461A KR20140130461A (ko) 2014-11-10
KR102148303B1 true KR102148303B1 (ko) 2020-08-26

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US (2) US20130209473A1 (enExample)
EP (1) EP2812350B1 (enExample)
JP (2) JP6545959B2 (enExample)
KR (1) KR102148303B1 (enExample)
CN (2) CN113398268A (enExample)
AR (1) AR089978A1 (enExample)
AU (1) AU2013216753B2 (enExample)
BR (1) BR112014019741A2 (enExample)
CA (1) CA2862316A1 (enExample)
HK (1) HK1211037A1 (enExample)
IL (2) IL233680B (enExample)
MX (1) MX366804B (enExample)
RU (1) RU2014133069A (enExample)
SG (1) SG11201404703WA (enExample)
WO (1) WO2013120056A1 (enExample)
ZA (1) ZA201406620B (enExample)

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EP3825411A1 (en) 2014-06-18 2021-05-26 Clear Gene, Inc. Methods, compositions, and devices for rapid analysis of biological markers
KR20170029490A (ko) 2014-07-11 2017-03-15 제넨테크, 인크. 노치 경로 억제
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US9777052B2 (en) 2014-12-02 2017-10-03 The Board Of Regents Of The University Of Oklahoma R-spondin variants, compositions, and methods of use
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KR20180010198A (ko) * 2015-05-26 2018-01-30 큐어제닉스 코포레이션 종양 바이오마커 및 이의 용도
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EP3455621B1 (en) * 2016-05-13 2023-07-19 Cincinnati Children's Hospital Medical Center Simplification of a septic shock endotyping strategy for clinical application
US11104953B2 (en) 2016-05-13 2021-08-31 Children's Hospital Medical Center Septic shock endotyping strategy and mortality risk for clinical application
KR102777127B1 (ko) 2016-08-02 2025-03-07 비스테라, 인크. 조작된 폴리펩티드 및 그의 용도
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EP3528841A1 (en) * 2016-10-20 2019-08-28 The Regents of The University of California Methods and compositions for the treatment of rna viral infections
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JP7352904B2 (ja) * 2019-10-08 2023-09-29 国立大学法人 東京大学 分析装置、分析方法及びプログラム
WO2021132574A1 (ja) 2019-12-27 2021-07-01 日本放送協会 送信装置及び受信装置
CN114480632B (zh) * 2020-11-16 2023-05-16 江萤 人微卫星不稳定位点的检测方法及其应用
CN113957075B (zh) * 2021-11-22 2023-04-07 百世诺(北京)医学检验实验室有限公司 突变的遗传性心律失常基因及其应用
CN114107482A (zh) * 2021-11-29 2022-03-01 百世诺(北京)医学检验实验室有限公司 肺动脉高压突变基因及其应用
KR102551095B1 (ko) * 2023-03-21 2023-07-04 순천향대학교 산학협력단 신규한 항-인간 알스폰딘2 항체 및 이의 용도
KR102554222B1 (ko) * 2023-03-21 2023-07-11 순천향대학교 산학협력단 신규한 항-인간 알스폰딘3 항체 및 이의 용도
CN119656337A (zh) * 2024-11-06 2025-03-21 中山大学附属第六医院 肿瘤细胞pcbp1基因突变调控cd8+t细胞在制备免疫治疗药物或制剂中的用途

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