KR102109317B1 - 고체 단백질 조성물의 신속한 용해를 위한 방법 및 장치 - Google Patents

고체 단백질 조성물의 신속한 용해를 위한 방법 및 장치 Download PDF

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Publication number
KR102109317B1
KR102109317B1 KR1020147021027A KR20147021027A KR102109317B1 KR 102109317 B1 KR102109317 B1 KR 102109317B1 KR 1020147021027 A KR1020147021027 A KR 1020147021027A KR 20147021027 A KR20147021027 A KR 20147021027A KR 102109317 B1 KR102109317 B1 KR 102109317B1
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KR
South Korea
Prior art keywords
closed container
fibrinogen
syringe
closed
movable seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020147021027A
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English (en)
Korean (ko)
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KR20140108709A (ko
Inventor
에레츠 이란
크피르 레제브
다나 레이트만
이스라엘 누르
모티 메론
죤 굿맨
Original Assignee
옴릭스 바이오파머슈티컬스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority claimed from IL217273A external-priority patent/IL217273A0/en
Application filed by 옴릭스 바이오파머슈티컬스 리미티드 filed Critical 옴릭스 바이오파머슈티컬스 리미티드
Publication of KR20140108709A publication Critical patent/KR20140108709A/ko
Application granted granted Critical
Publication of KR102109317B1 publication Critical patent/KR102109317B1/ko
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
    • B01F25/4512—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture with reciprocating pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25—Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • B01F33/251—Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7163—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected in a mouth-to-mouth, end-to-end disposition, i.e. the openings are juxtaposed before contacting the contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/718—Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Peptides Or Proteins (AREA)
KR1020147021027A 2011-12-29 2012-12-20 고체 단백질 조성물의 신속한 용해를 위한 방법 및 장치 Expired - Fee Related KR102109317B1 (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
IL217273A IL217273A0 (en) 2011-12-29 2011-12-29 Fast dissolution of solid fibrinogen
IL217273 2011-12-29
US201261582524P 2012-01-03 2012-01-03
US61/582,524 2012-01-03
US201261677048P 2012-07-30 2012-07-30
US61/677,048 2012-07-30
IL22118012 2012-07-30
IL221180 2012-07-30
PCT/IL2012/000393 WO2013098805A1 (en) 2011-12-29 2012-12-20 Method and device for fast dissolution of solid protein composition

Publications (2)

Publication Number Publication Date
KR20140108709A KR20140108709A (ko) 2014-09-12
KR102109317B1 true KR102109317B1 (ko) 2020-05-29

Family

ID=48696437

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147021027A Expired - Fee Related KR102109317B1 (ko) 2011-12-29 2012-12-20 고체 단백질 조성물의 신속한 용해를 위한 방법 및 장치

Country Status (13)

Country Link
US (2) US10618950B2 (enExample)
EP (1) EP2797681B1 (enExample)
JP (1) JP6223999B2 (enExample)
KR (1) KR102109317B1 (enExample)
AU (1) AU2012360048B2 (enExample)
BR (1) BR112014016193A8 (enExample)
CA (2) CA3078563A1 (enExample)
ES (1) ES2621363T3 (enExample)
IL (1) IL233361B (enExample)
IN (1) IN2014DN05901A (enExample)
MX (1) MX351980B (enExample)
RU (1) RU2605710C2 (enExample)
WO (1) WO2013098805A1 (enExample)

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IL244922A0 (en) * 2016-04-05 2016-07-31 Omrix Biopharmaceuticals Ltd Device and method for sample preparation
US11071782B2 (en) 2016-04-20 2021-07-27 Coherus Biosciences, Inc. Method of filling a container with no headspace
US10150115B2 (en) * 2016-07-21 2018-12-11 Spacepharma SA System and method for rehydrating powder and delivering the rehydrated powder to a reactor
WO2018150375A1 (en) * 2017-02-17 2018-08-23 Baxter International Inc. Devices and methods for forming and delivering a tissue sealant
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EP4452233B1 (en) 2021-12-21 2025-12-24 Omrix Biopharmaceuticals Ltd. Highly soluble fibrinogen compositions

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Also Published As

Publication number Publication date
CA2861722A1 (en) 2013-07-04
US11634473B2 (en) 2023-04-25
CN104144742A (zh) 2014-11-12
RU2605710C2 (ru) 2016-12-27
EP2797681A1 (en) 2014-11-05
JP6223999B2 (ja) 2017-11-01
WO2013098805A1 (en) 2013-07-04
MX2014008033A (es) 2014-12-08
US20130312868A1 (en) 2013-11-28
RU2014131276A (ru) 2016-02-20
US20200262892A1 (en) 2020-08-20
JP2015509084A (ja) 2015-03-26
BR112014016193A8 (pt) 2017-07-04
US10618950B2 (en) 2020-04-14
MX351980B (es) 2017-11-03
CA3078563A1 (en) 2013-07-04
KR20140108709A (ko) 2014-09-12
CA2861722C (en) 2020-06-30
EP2797681B1 (en) 2017-02-01
BR112014016193A2 (pt) 2017-06-13
IL233361A0 (en) 2014-08-31
AU2012360048B2 (en) 2017-05-25
IL233361B (en) 2018-06-28
AU2012360048A1 (en) 2014-08-14
ES2621363T3 (es) 2017-07-03
HK1203438A1 (en) 2015-10-30
IN2014DN05901A (enExample) 2015-06-05

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