IN2014DN05901A - - Google Patents
Info
- Publication number
- IN2014DN05901A IN2014DN05901A IN5901DEN2014A IN2014DN05901A IN 2014DN05901 A IN2014DN05901 A IN 2014DN05901A IN 5901DEN2014 A IN5901DEN2014 A IN 5901DEN2014A IN 2014DN05901 A IN2014DN05901 A IN 2014DN05901A
- Authority
- IN
- India
- Prior art keywords
- pressure
- solid
- headspace
- devices
- aqueous solvent
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/50—Mixing liquids with solids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
- B01F25/4512—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture with reciprocating pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/25—Mixers with loose mixing elements, e.g. loose balls in a receptacle
- B01F33/251—Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
- B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7163—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected in a mouth-to-mouth, end-to-end disposition, i.e. the openings are juxtaposed before contacting the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/718—Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Provided are methods and devices for dissolving solid protein compositions such as solid compositions comprising fibrinogen in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub atmospheric. Aqueous solvent is introduced into the container while maintain the sub atmospheric pressure and subsequent to addition of the solvent the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL217273A IL217273A0 (en) | 2011-12-29 | 2011-12-29 | Fast dissolution of solid fibrinogen |
US201261582524P | 2012-01-03 | 2012-01-03 | |
US201261677048P | 2012-07-30 | 2012-07-30 | |
IL22118012 | 2012-07-30 | ||
PCT/IL2012/000393 WO2013098805A1 (en) | 2011-12-29 | 2012-12-20 | Method and device for fast dissolution of solid protein composition |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014DN05901A true IN2014DN05901A (en) | 2015-06-05 |
Family
ID=48696437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN5901DEN2014 IN2014DN05901A (en) | 2011-12-29 | 2012-12-20 |
Country Status (14)
Country | Link |
---|---|
US (2) | US10618950B2 (en) |
EP (1) | EP2797681B1 (en) |
JP (1) | JP6223999B2 (en) |
KR (1) | KR102109317B1 (en) |
AU (1) | AU2012360048B2 (en) |
BR (1) | BR112014016193A8 (en) |
CA (2) | CA2861722C (en) |
ES (1) | ES2621363T3 (en) |
HK (1) | HK1203438A1 (en) |
IL (1) | IL233361B (en) |
IN (1) | IN2014DN05901A (en) |
MX (1) | MX351980B (en) |
RU (1) | RU2605710C2 (en) |
WO (1) | WO2013098805A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10618950B2 (en) | 2011-12-29 | 2020-04-14 | Omrix Biopharmaceuticals Ltd. | Method and device for fast dissolution of solid protein composition |
AU2015207464B2 (en) | 2014-01-20 | 2019-10-03 | Eveon | Process for reconstitution of a solid form of a pharmaceutical composition |
US20170274012A1 (en) * | 2014-09-03 | 2017-09-28 | Entegrion, Inc. | Acceleration of Reconstitution of Plasma Powder by Mixing with Small Beads |
US11229702B1 (en) | 2015-10-28 | 2022-01-25 | Coherus Biosciences, Inc. | High concentration formulations of adalimumab |
USD877891S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution and delivery device |
USD829888S1 (en) * | 2015-12-22 | 2018-10-02 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution and delivery device |
USD877890S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution device |
US10918790B2 (en) * | 2015-12-22 | 2021-02-16 | Guangzhou Bioseal Biotech Co., Ltd. | Dual syringe with funnel feeding kit |
IL244922A0 (en) * | 2016-04-05 | 2016-07-31 | Omrix Biopharmaceuticals Ltd | Device and process for sample preparation |
WO2017184880A1 (en) | 2016-04-20 | 2017-10-26 | Coherus Biosciences, Inc. | A method of filling a container with no headspace |
US10150115B2 (en) * | 2016-07-21 | 2018-12-11 | Spacepharma SA | System and method for rehydrating powder and delivering the rehydrated powder to a reactor |
WO2018150375A1 (en) * | 2017-02-17 | 2018-08-23 | Baxter International Inc. | Devices and methods for forming and delivering a tissue sealant |
US11717797B2 (en) | 2017-07-06 | 2023-08-08 | Plas-Tech Engineering, Inc. | Systems and methods related to fluid pumping |
WO2023119277A1 (en) | 2021-12-21 | 2023-06-29 | Omrix Biopharmaceuticals Ltd. | Highly soluble fibrinogen compositions |
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US3405712A (en) * | 1966-02-07 | 1968-10-15 | Richard L. Pierick | Desiccative syringe |
AT366916B (en) * | 1980-04-02 | 1982-05-25 | Immuno Ag | DEVICE FOR APPLICATING A TISSUE ADHESIVE BASED ON HUMAN OR ANIMAL PROTEINS |
AT371719B (en) | 1980-08-25 | 1983-07-25 | Immuno Ag | METHOD AND DEVICE FOR ACCELERATING THE DISOLDERING OF SLAVE-LYOPHILIZED MEDICINAL PRODUCTS |
DE3203775A1 (en) | 1982-02-04 | 1983-08-11 | Behringwerke Ag, 3550 Marburg | FIBRINOGEN PREPARATION, METHOD FOR THEIR PRODUCTION AND THEIR USE |
US4610666A (en) * | 1985-06-24 | 1986-09-09 | Pizzino Joanne L | Dual syringe |
US4742128A (en) * | 1985-10-15 | 1988-05-03 | Stamicarbon B.V. | Process for preparing a polymer alloy, molded product, and reaction injection molded products |
US4978336A (en) * | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
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AT392972B (en) | 1988-08-16 | 1991-07-25 | Chemiefaser Lenzing Ag | METHOD FOR PRODUCING SOLUTIONS OF CELLULOSE AND DEVICE FOR IMPLEMENTING THE METHOD |
SU1697836A1 (en) * | 1989-01-24 | 1991-12-15 | Московский научно-исследовательский онкологический институт им.П.А.Герцена | Device for mixing and introducing liquid fast self-structurizing components |
US5122117A (en) * | 1990-06-05 | 1992-06-16 | Habley Medical Technology Corp. | Component mixing syringe |
US5181909A (en) * | 1991-05-15 | 1993-01-26 | Mcfarlane Richard H | Ampule-container medical syringe and methods |
US5792835A (en) * | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
EP0534178B1 (en) | 1991-09-27 | 2001-04-18 | Omrix Biopharmaceuticals S.A. | Improved tissue glue prepared by using cryoprecipitate |
JP3063935B2 (en) | 1992-05-12 | 2000-07-12 | 宇部興産株式会社 | Polyimide siloxane composition having adhesiveness, heat resistance and curl resistance |
US5599790A (en) * | 1992-06-11 | 1997-02-04 | The Scripps Research Institute | Fibrinogen γ chain polypeptide and compositions thereof |
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DE102005017985A1 (en) * | 2005-04-19 | 2006-10-26 | Theo Arnitz | Accelerated dissolving of dry pharmaceutical products for injection, comprises locking filled active substance container under vacuum with plug, durably storing substance, adding liquid to substance, mixing and dissolving substance |
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ATE473693T1 (en) * | 2006-01-17 | 2010-07-15 | Baxter Int | MIXING APPARATUS, SYSTEM AND METHOD |
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CN101534952B (en) * | 2006-11-02 | 2012-10-31 | 欧姆瑞克斯生物医药有限公司 | Method of micronization |
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JP5393447B2 (en) | 2007-03-22 | 2014-01-22 | 一般財団法人化学及血清療法研究所 | Solid fibrinogen preparation |
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JP5264545B2 (en) * | 2008-06-16 | 2013-08-14 | テルモ株式会社 | Liquid mixing method |
JP5318684B2 (en) * | 2009-07-14 | 2013-10-16 | テルモ株式会社 | Syringe and syringe assembly |
CA2766229A1 (en) * | 2009-09-08 | 2011-03-17 | Baxter International Inc. | Reconstitution and applicator system for wound sealant product |
US10618950B2 (en) | 2011-12-29 | 2020-04-14 | Omrix Biopharmaceuticals Ltd. | Method and device for fast dissolution of solid protein composition |
-
2012
- 2012-12-20 US US13/722,348 patent/US10618950B2/en active Active
- 2012-12-20 EP EP12815839.1A patent/EP2797681B1/en not_active Not-in-force
- 2012-12-20 JP JP2014549630A patent/JP6223999B2/en not_active Expired - Fee Related
- 2012-12-20 IN IN5901DEN2014 patent/IN2014DN05901A/en unknown
- 2012-12-20 BR BR112014016193A patent/BR112014016193A8/en active Search and Examination
- 2012-12-20 RU RU2014131276/05A patent/RU2605710C2/en not_active IP Right Cessation
- 2012-12-20 KR KR1020147021027A patent/KR102109317B1/en active IP Right Grant
- 2012-12-20 WO PCT/IL2012/000393 patent/WO2013098805A1/en active Application Filing
- 2012-12-20 CA CA2861722A patent/CA2861722C/en not_active Expired - Fee Related
- 2012-12-20 CA CA3078563A patent/CA3078563A1/en not_active Abandoned
- 2012-12-20 ES ES12815839.1T patent/ES2621363T3/en active Active
- 2012-12-20 MX MX2014008033A patent/MX351980B/en active IP Right Grant
- 2012-12-20 AU AU2012360048A patent/AU2012360048B2/en not_active Ceased
-
2014
- 2014-06-24 IL IL233361A patent/IL233361B/en active IP Right Grant
-
2015
- 2015-04-30 HK HK15104175.2A patent/HK1203438A1/en not_active IP Right Cessation
-
2020
- 2020-03-10 US US16/814,088 patent/US11634473B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR102109317B1 (en) | 2020-05-29 |
AU2012360048A1 (en) | 2014-08-14 |
CA2861722C (en) | 2020-06-30 |
CA3078563A1 (en) | 2013-07-04 |
US20130312868A1 (en) | 2013-11-28 |
WO2013098805A1 (en) | 2013-07-04 |
US11634473B2 (en) | 2023-04-25 |
KR20140108709A (en) | 2014-09-12 |
MX351980B (en) | 2017-11-03 |
RU2605710C2 (en) | 2016-12-27 |
BR112014016193A2 (en) | 2017-06-13 |
US20200262892A1 (en) | 2020-08-20 |
IL233361B (en) | 2018-06-28 |
IL233361A0 (en) | 2014-08-31 |
EP2797681B1 (en) | 2017-02-01 |
JP2015509084A (en) | 2015-03-26 |
BR112014016193A8 (en) | 2017-07-04 |
CN104144742A (en) | 2014-11-12 |
AU2012360048B2 (en) | 2017-05-25 |
EP2797681A1 (en) | 2014-11-05 |
CA2861722A1 (en) | 2013-07-04 |
RU2014131276A (en) | 2016-02-20 |
JP6223999B2 (en) | 2017-11-01 |
US10618950B2 (en) | 2020-04-14 |
HK1203438A1 (en) | 2015-10-30 |
ES2621363T3 (en) | 2017-07-03 |
MX2014008033A (en) | 2014-12-08 |
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