IL233361B - Method and device for rapidly dissolving a solid proteinaceous compound - Google Patents
Method and device for rapidly dissolving a solid proteinaceous compoundInfo
- Publication number
- IL233361B IL233361B IL233361A IL23336114A IL233361B IL 233361 B IL233361 B IL 233361B IL 233361 A IL233361 A IL 233361A IL 23336114 A IL23336114 A IL 23336114A IL 233361 B IL233361 B IL 233361B
- Authority
- IL
- Israel
- Prior art keywords
- protein composition
- solid protein
- fast dissolution
- dissolution
- fast
- Prior art date
Links
- 238000004090 dissolution Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/50—Mixing liquids with solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
- B01F25/451—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture
- B01F25/4512—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by means for moving the materials to be mixed or the mixture with reciprocating pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/25—Mixers with loose mixing elements, e.g. loose balls in a receptacle
- B01F33/251—Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/50—Movable or transportable mixing devices or plants
- B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
- B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
- B01F33/50112—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held of the syringe or cartridge type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7163—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected in a mouth-to-mouth, end-to-end disposition, i.e. the openings are juxtaposed before contacting the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/718—Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL233361A IL233361B (en) | 2011-12-29 | 2014-06-24 | Method and device for rapidly dissolving a solid proteinaceous compound |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL217273A IL217273A0 (en) | 2011-12-29 | 2011-12-29 | Fast dissolution of solid fibrinogen |
| US201261582524P | 2012-01-03 | 2012-01-03 | |
| US201261677048P | 2012-07-30 | 2012-07-30 | |
| IL22118012 | 2012-07-30 | ||
| PCT/IL2012/000393 WO2013098805A1 (en) | 2011-12-29 | 2012-12-20 | Method and device for fast dissolution of solid protein composition |
| IL233361A IL233361B (en) | 2011-12-29 | 2014-06-24 | Method and device for rapidly dissolving a solid proteinaceous compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL233361A0 IL233361A0 (en) | 2014-08-31 |
| IL233361B true IL233361B (en) | 2018-06-28 |
Family
ID=48696437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL233361A IL233361B (en) | 2011-12-29 | 2014-06-24 | Method and device for rapidly dissolving a solid proteinaceous compound |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10618950B2 (enExample) |
| EP (1) | EP2797681B1 (enExample) |
| JP (1) | JP6223999B2 (enExample) |
| KR (1) | KR102109317B1 (enExample) |
| AU (1) | AU2012360048B2 (enExample) |
| BR (1) | BR112014016193A8 (enExample) |
| CA (2) | CA2861722C (enExample) |
| ES (1) | ES2621363T3 (enExample) |
| IL (1) | IL233361B (enExample) |
| IN (1) | IN2014DN05901A (enExample) |
| MX (1) | MX351980B (enExample) |
| RU (1) | RU2605710C2 (enExample) |
| WO (1) | WO2013098805A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2605710C2 (ru) | 2011-12-29 | 2016-12-27 | Омрикс Биофармасьютикалс Лтд. | Способ и устройство для быстрого растворения твердой белковой композиции |
| BR112016016690A2 (pt) | 2014-01-20 | 2018-03-20 | 1 Eveon 2 Ucb Biopharma Sprl | processo para a reconstituição de uma forma sólida de uma composição farmacêutica |
| US20170274012A1 (en) * | 2014-09-03 | 2017-09-28 | Entegrion, Inc. | Acceleration of Reconstitution of Plasma Powder by Mixing with Small Beads |
| US11229702B1 (en) | 2015-10-28 | 2022-01-25 | Coherus Biosciences, Inc. | High concentration formulations of adalimumab |
| US10918790B2 (en) * | 2015-12-22 | 2021-02-16 | Guangzhou Bioseal Biotech Co., Ltd. | Dual syringe with funnel feeding kit |
| USD877890S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution device |
| USD829888S1 (en) * | 2015-12-22 | 2018-10-02 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution and delivery device |
| USD877891S1 (en) | 2015-12-22 | 2020-03-10 | Guangzhou Bioseal Biotech Co., Ltd. | Reconstitution and delivery device |
| IL244922A0 (en) * | 2016-04-05 | 2016-07-31 | Omrix Biopharmaceuticals Ltd | Device and method for sample preparation |
| WO2017184880A1 (en) | 2016-04-20 | 2017-10-26 | Coherus Biosciences, Inc. | A method of filling a container with no headspace |
| US10150115B2 (en) * | 2016-07-21 | 2018-12-11 | Spacepharma SA | System and method for rehydrating powder and delivering the rehydrated powder to a reactor |
| WO2018150375A1 (en) * | 2017-02-17 | 2018-08-23 | Baxter International Inc. | Devices and methods for forming and delivering a tissue sealant |
| AU2018204933B2 (en) | 2017-07-06 | 2024-08-22 | Plas-Tech Engineering, Inc. | Systems and methods related to fluid pumping |
| WO2023119277A1 (en) | 2021-12-21 | 2023-06-29 | Omrix Biopharmaceuticals Ltd. | Highly soluble fibrinogen compositions |
Family Cites Families (48)
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| US3052240A (en) * | 1959-01-29 | 1962-09-04 | Silver | Disposable hypodermic syringe |
| US3405712A (en) * | 1966-02-07 | 1968-10-15 | Richard L. Pierick | Desiccative syringe |
| AT366916B (de) * | 1980-04-02 | 1982-05-25 | Immuno Ag | Vorrichtung zur applikation eines gewebeklebstoffes auf basis von menschlichen oder tierischenproteinen |
| AT371719B (de) | 1980-08-25 | 1983-07-25 | Immuno Ag | Verfahren und vorrichtung zur beschleunigung des aufloesens von schwerloeslichen lyophilisierten arzneimitteln |
| DE3203775A1 (de) | 1982-02-04 | 1983-08-11 | Behringwerke Ag, 3550 Marburg | Fibrinogenzubereitung, verfahen zu ihrer herstellungund ihre verwendung |
| US4610666A (en) * | 1985-06-24 | 1986-09-09 | Pizzino Joanne L | Dual syringe |
| US4742128A (en) * | 1985-10-15 | 1988-05-03 | Stamicarbon B.V. | Process for preparing a polymer alloy, molded product, and reaction injection molded products |
| US4978336A (en) * | 1987-09-29 | 1990-12-18 | Hemaedics, Inc. | Biological syringe system |
| AT397203B (de) | 1988-05-31 | 1994-02-25 | Immuno Ag | Gewebeklebstoff |
| AT392972B (de) | 1988-08-16 | 1991-07-25 | Chemiefaser Lenzing Ag | Verfahren zur herstellung von loesungen von cellulose sowie einrichtung zur durchfuehrung des verfahrens |
| SU1697836A1 (ru) | 1989-01-24 | 1991-12-15 | Московский научно-исследовательский онкологический институт им.П.А.Герцена | Устройство дл смешивани и введени жидких быстроструктурирующихс компонентов |
| US5122117A (en) * | 1990-06-05 | 1992-06-16 | Habley Medical Technology Corp. | Component mixing syringe |
| US5181909A (en) * | 1991-05-15 | 1993-01-26 | Mcfarlane Richard H | Ampule-container medical syringe and methods |
| US5792835A (en) * | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
| EP0534178B1 (en) | 1991-09-27 | 2001-04-18 | Omrix Biopharmaceuticals S.A. | Improved tissue glue prepared by using cryoprecipitate |
| JP3063935B2 (ja) | 1992-05-12 | 2000-07-12 | 宇部興産株式会社 | 接着性、耐熱性および耐カ−ル性を兼ね備えたポリイミドシロキサン組成物 |
| US5599790A (en) * | 1992-06-11 | 1997-02-04 | The Scripps Research Institute | Fibrinogen γ chain polypeptide and compositions thereof |
| US5330974A (en) * | 1993-03-01 | 1994-07-19 | Fibratek, Inc. | Therapeutic fibrinogen compositions |
| AT400675B (de) * | 1993-10-18 | 1996-02-26 | Immuno Ag | Spritzengarnitur zur aufbewahrung und applikation eines mehrkomponentenmaterials, spritzenvorrichtung und betätigungseinrichtung hiefür sowie verfahren zum herstellen einer befüllten, sterilen spritzenvorrichtung |
| US6965014B1 (en) * | 1996-01-16 | 2005-11-15 | Baxter International Inc. | Fibrin material and method for producing and using the same |
| US6599515B1 (en) * | 1995-01-16 | 2003-07-29 | Baxter International Inc. | Fibrin porous structure |
| DE69734557T2 (de) | 1996-03-15 | 2006-07-27 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Sprühvorrichtung zum aufbringen von gewebeklebstoff |
| DE19617369A1 (de) | 1996-04-30 | 1997-11-06 | Immuno Ag | Lagerstabile Fibrinogen-Präparate |
| FR2749169B1 (fr) | 1996-06-04 | 1998-08-21 | Delab | Procede pour constituer une preparation injectable et dispositif pour la mise en oeuvre de ce procede |
| JP3420892B2 (ja) * | 1996-07-25 | 2003-06-30 | 高橋 宏嘉 | 指圧代用刺激具及びその製造方法 |
| JP3063935U (ja) | 1999-05-17 | 1999-12-10 | 川澄化学工業株式会社 | 二液同時混合注出器及びプランジャ結合部材 |
| AU2001287023A1 (en) * | 2000-09-01 | 2002-03-13 | Virginia Commonwealth University Intellectual Property Foundation | Plasma-derived-fibrin-based matrices and tissue |
| JP4385097B2 (ja) | 2001-05-21 | 2009-12-16 | オムリックス・バイオファーマシューティカルズ・エス．アー． | 蛋白質溶液からのプラスミノゲン（プラスミン）の除去 |
| DE10211227A1 (de) | 2002-03-13 | 2003-10-02 | Aventis Behring Gmbh | Verfahren zur Rekonstitution von Iyophilisierten Proteinen |
| ATE345277T1 (de) * | 2002-08-21 | 2006-12-15 | Pharmacia Corp | Injizierbare pharmazeutische suspension in einer phiole mit zwei kammern |
| DE20216631U1 (de) | 2002-10-28 | 2004-03-11 | Haindl, Hans, Dr.med. | Selbstentlüftende Spritze für das Mischen von flüssigen und pulverförmigen Substanzen |
| WO2004067704A2 (en) * | 2003-01-30 | 2004-08-12 | Prochon Biotech Ltd. | Freeze-dried fibrin matrices and methods for preparation thereof |
| US6669667B1 (en) * | 2003-04-11 | 2003-12-30 | Jih-Hsiung Yang | Safety syringe |
| HRP20140442T1 (hr) * | 2003-06-23 | 2014-07-04 | Kiacta Sàrl | Metoda za pripremu spoja 1,3-propan disulfonske kiseline |
| DE102005017985A1 (de) * | 2005-04-19 | 2006-10-26 | Theo Arnitz | Verfahren und Vorrichtungen zum Auflösen von Medikamenten für Injektionen |
| US20080167621A1 (en) * | 2005-05-16 | 2008-07-10 | Wagner Gary S | Multi-Barrel Syringe Having Integral Manifold |
| DE602007007725D1 (de) * | 2006-01-17 | 2010-08-26 | Baxter Healthcare Sa | Mischvorrichtung, -system und -verfahren |
| DE102006009611A1 (de) | 2006-03-02 | 2007-09-06 | Bernd Hansen | System zum Zubereiten und Bereitstellen eines durch Vermischen einer Trockensubstanz mit einem Fluid gebildeten fließfähigen Mediums |
| JP5373618B2 (ja) | 2006-11-02 | 2013-12-18 | オムリクス バイオファーマシューティカルズ リミテッド | 微粒化方法 |
| US20080221584A1 (en) * | 2007-03-06 | 2008-09-11 | Downer David A | Lens Delivery System |
| AU2008230476B2 (en) | 2007-03-22 | 2012-11-01 | Km Biologics Co., Ltd. | Solid fibrinogen preparation |
| DE102008003103A1 (de) | 2008-01-01 | 2009-07-02 | Lts Lohmann Therapie-Systeme Ag | Einweginjektor mit zweikolbigem Zweikammersystem |
| US20090198211A1 (en) * | 2008-02-06 | 2009-08-06 | Intravena, Llc | Convenience IV kits and methods of use |
| US8512740B2 (en) * | 2008-03-26 | 2013-08-20 | Baxter International Inc. | Fibrin foam and process for making |
| JP5264545B2 (ja) | 2008-06-16 | 2013-08-14 | テルモ株式会社 | 液体混合方法 |
| JP5318684B2 (ja) | 2009-07-14 | 2013-10-16 | テルモ株式会社 | シリンジおよびシリンジ連結体 |
| WO2011031783A1 (en) * | 2009-09-08 | 2011-03-17 | Baxter International Inc. | Reconstitution and applicator system for wound sealant product |
| RU2605710C2 (ru) | 2011-12-29 | 2016-12-27 | Омрикс Биофармасьютикалс Лтд. | Способ и устройство для быстрого растворения твердой белковой композиции |
-
2012
- 2012-12-20 RU RU2014131276/05A patent/RU2605710C2/ru not_active IP Right Cessation
- 2012-12-20 JP JP2014549630A patent/JP6223999B2/ja not_active Expired - Fee Related
- 2012-12-20 IN IN5901DEN2014 patent/IN2014DN05901A/en unknown
- 2012-12-20 BR BR112014016193A patent/BR112014016193A8/pt active Search and Examination
- 2012-12-20 CA CA2861722A patent/CA2861722C/en not_active Expired - Fee Related
- 2012-12-20 ES ES12815839.1T patent/ES2621363T3/es active Active
- 2012-12-20 US US13/722,348 patent/US10618950B2/en active Active
- 2012-12-20 MX MX2014008033A patent/MX351980B/es active IP Right Grant
- 2012-12-20 EP EP12815839.1A patent/EP2797681B1/en not_active Not-in-force
- 2012-12-20 CA CA3078563A patent/CA3078563A1/en not_active Abandoned
- 2012-12-20 AU AU2012360048A patent/AU2012360048B2/en not_active Ceased
- 2012-12-20 WO PCT/IL2012/000393 patent/WO2013098805A1/en not_active Ceased
- 2012-12-20 KR KR1020147021027A patent/KR102109317B1/ko not_active Expired - Fee Related
-
2014
- 2014-06-24 IL IL233361A patent/IL233361B/en active IP Right Grant
-
2020
- 2020-03-10 US US16/814,088 patent/US11634473B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2797681A1 (en) | 2014-11-05 |
| CA3078563A1 (en) | 2013-07-04 |
| CN104144742A (zh) | 2014-11-12 |
| BR112014016193A8 (pt) | 2017-07-04 |
| IN2014DN05901A (enExample) | 2015-06-05 |
| WO2013098805A1 (en) | 2013-07-04 |
| RU2605710C2 (ru) | 2016-12-27 |
| KR102109317B1 (ko) | 2020-05-29 |
| US20130312868A1 (en) | 2013-11-28 |
| CA2861722A1 (en) | 2013-07-04 |
| EP2797681B1 (en) | 2017-02-01 |
| US20200262892A1 (en) | 2020-08-20 |
| US11634473B2 (en) | 2023-04-25 |
| RU2014131276A (ru) | 2016-02-20 |
| US10618950B2 (en) | 2020-04-14 |
| JP2015509084A (ja) | 2015-03-26 |
| KR20140108709A (ko) | 2014-09-12 |
| IL233361A0 (en) | 2014-08-31 |
| CA2861722C (en) | 2020-06-30 |
| AU2012360048B2 (en) | 2017-05-25 |
| MX351980B (es) | 2017-11-03 |
| AU2012360048A1 (en) | 2014-08-14 |
| HK1203438A1 (en) | 2015-10-30 |
| ES2621363T3 (es) | 2017-07-03 |
| MX2014008033A (es) | 2014-12-08 |
| JP6223999B2 (ja) | 2017-11-01 |
| BR112014016193A2 (pt) | 2017-06-13 |
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