KR102070098B1 - 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법 - Google Patents

다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법 Download PDF

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KR102070098B1
KR102070098B1 KR1020187033586A KR20187033586A KR102070098B1 KR 102070098 B1 KR102070098 B1 KR 102070098B1 KR 1020187033586 A KR1020187033586 A KR 1020187033586A KR 20187033586 A KR20187033586 A KR 20187033586A KR 102070098 B1 KR102070098 B1 KR 102070098B1
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fusion protein
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KR20180126632A (ko
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힝 씨. 웡
피터 로데
바이 리우
지아오윤 주
카이-핑 한
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알토 바이오사이언스 코포레이션
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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KR1020187033586A 2010-09-21 2011-09-21 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법 Active KR102070098B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38481710P 2010-09-21 2010-09-21
US61/384,817 2010-09-21
US201161527911P 2011-08-26 2011-08-26
US61/527,911 2011-08-26
PCT/US2011/052545 WO2012040323A2 (en) 2010-09-21 2011-09-21 Multimeric il-15 soluble fusion molecules and methods of making and using same

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KR102070098B1 true KR102070098B1 (ko) 2020-01-28

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KR1020187033586A Active KR102070098B1 (ko) 2010-09-21 2011-09-21 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법

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US (11) US8507222B2 (enExample)
EP (5) EP4385570A3 (enExample)
JP (4) JP6251570B2 (enExample)
KR (2) KR20140020228A (enExample)
CN (3) CN105017429B (enExample)
AU (2) AU2011305476B2 (enExample)
CA (1) CA2811734C (enExample)
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11046747B2 (en) 2010-09-21 2021-06-29 Altor Bioscience Llc Multimeric IL-15 soluble fusion molecules and methods of making and using same
US11053299B2 (en) 2010-09-21 2021-07-06 Immunity Bio, Inc. Superkine
US11173191B2 (en) 2014-06-30 2021-11-16 Altor BioScience, LLC. IL-15-based molecules and methods of use thereof
US11318201B2 (en) 2016-10-21 2022-05-03 Altor BioScience, LLC. Multimeric IL-15-based molecules
US11365231B2 (en) 2007-05-11 2022-06-21 Altor Bioscience, Llc Interleukin 15 (IL-15) variants

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1899364B2 (en) 2005-05-17 2024-10-30 University of Connecticut Compositions and methods for immunomodulation in an organism
SG176468A1 (en) 2005-12-02 2011-12-29 Sinai School Medicine Chimeric viruses presenting non-native surface proteins and uses thereof
WO2007084342A2 (en) 2006-01-13 2007-07-26 The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Codon optimi zed il- 15 and il- 15r-alpha genes for expression in mammalian cells
DK2173378T3 (da) 2007-06-27 2014-05-12 Admune Therapeutics Llc Komplekser af il-15 og il-15ralfa og anvendelser deraf
WO2018112219A1 (en) * 2016-12-14 2018-06-21 Nant Holdings Ip, Llc Superkine
DK2663579T3 (en) 2011-01-14 2017-07-31 Univ California THERAPEUTIC ANTIBODIES AGAINST ROR-1 PROTEIN AND PROCEDURES FOR USE THEREOF
CA2869786A1 (en) * 2012-06-08 2013-12-12 Alkermes, Inc. Fusion polypeptides comprising mucin-domain polypeptide linkers
AU2013334610B2 (en) 2012-10-24 2018-09-13 Novartis Ag IL-15R alpha forms, cells expressing IL-15R alpha forms, and therapeutic uses of IL-15R alpha and IL-15/IL-15R alpha complexes
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