KR102055772B1 - 약물 전달을 위한 티타니아 나노튜브 멤브레인을 갖는 디바이스 - Google Patents

약물 전달을 위한 티타니아 나노튜브 멤브레인을 갖는 디바이스 Download PDF

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KR102055772B1
KR102055772B1 KR1020147018695A KR20147018695A KR102055772B1 KR 102055772 B1 KR102055772 B1 KR 102055772B1 KR 1020147018695 A KR1020147018695 A KR 1020147018695A KR 20147018695 A KR20147018695 A KR 20147018695A KR 102055772 B1 KR102055772 B1 KR 102055772B1
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titania
nanotubes
nanotube membrane
titanium substrate
titania nanotubes
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KR20140106660A (ko
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아담 디. 멘델존
캐슬린 이. 피셔
릴리 에이치. 펭
윌리엄 쥐. 피셔
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나노 프리시전 메디컬, 인코포레이티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02Anodisation
    • C25D11/26Anodisation of refractory metals or alloys based thereon
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C25D11/02Anodisation
    • C25D11/34Anodisation of metals or alloys not provided for in groups C25D11/04 - C25D11/32
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D5/00Electroplating characterised by the process; Pretreatment or after-treatment of workpieces
    • C25D5/48After-treatment of electroplated surfaces
    • CCHEMISTRY; METALLURGY
    • C25ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25DPROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D5/00Electroplating characterised by the process; Pretreatment or after-treatment of workpieces
    • C25D5/48After-treatment of electroplated surfaces
    • C25D5/50After-treatment of electroplated surfaces by heat-treatment
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00Control; Monitoring or safety arrangements
    • F04C2270/04Force
    • F04C2270/041Controlled or regulated

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Metallurgy (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
KR1020147018695A 2011-12-05 2012-12-05 약물 전달을 위한 티타니아 나노튜브 멤브레인을 갖는 디바이스 Active KR102055772B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161566810P 2011-12-05 2011-12-05
US61/566,810 2011-12-05
PCT/US2012/067868 WO2013085951A1 (en) 2011-12-05 2012-12-05 Device having titania nanotube membrane for drug delivery

Publications (2)

Publication Number Publication Date
KR20140106660A KR20140106660A (ko) 2014-09-03
KR102055772B1 true KR102055772B1 (ko) 2019-12-13

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US (1) US9814867B2 (enExample)
EP (1) EP2788439A4 (enExample)
JP (2) JP6564187B2 (enExample)
KR (1) KR102055772B1 (enExample)
CN (1) CN103998536B (enExample)
WO (1) WO2013085951A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2807552A1 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3431485B2 (en) 2010-10-01 2024-09-04 ModernaTX, Inc. Engineered nucleic acids and methods of use thereof
WO2012135805A2 (en) 2011-03-31 2012-10-04 modeRNA Therapeutics Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP2763701B1 (en) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
JP6564187B2 (ja) * 2011-12-05 2019-08-21 ナノ プレシジョン メディカル インコーポレイテッドNano Precision Medical, Inc. チタニアナノチューブ膜を有する、薬物送達用デバイス
KR20140102759A (ko) 2011-12-16 2014-08-22 모더나 세라퓨틱스, 인코포레이티드 변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
DE18200782T1 (de) 2012-04-02 2021-10-21 Modernatx, Inc. Modifizierte polynukleotide zur herstellung von proteinen im zusammenhang mit erkrankungen beim menschen
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
CA2892529C (en) 2012-11-26 2023-04-25 Moderna Therapeutics, Inc. Terminally modified rna
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
EA201690675A1 (ru) 2013-10-03 2016-08-31 Модерна Терапьютикс, Инк. Полинуклеотиды, кодирующие рецептор липопротеинов низкой плотности
US9770412B2 (en) 2014-01-23 2017-09-26 Nano Precision Medical, Inc. Implant device for drug delivery
KR101458486B1 (ko) * 2014-02-26 2014-11-07 재단법인대구경북과학기술원 다공성 한방침 및 이의 제조방법
WO2021173770A1 (en) 2020-02-28 2021-09-02 Nano Precision Medical, Inc. Polymeric stabilizing agents for implantable drug delivery devices
US12071516B2 (en) 2014-09-04 2024-08-27 Nano Precision Medical, Inc. Polymeric stabilizing formulations
WO2016037128A1 (en) * 2014-09-04 2016-03-10 Nano Precision Medical, Inc. Polymeric stabilizing formulations
US20230022463A1 (en) * 2014-11-02 2023-01-26 Nano Precision Medical, Inc. Implantable medical devices for extended release of therapeutic agents
EP3212170B1 (en) * 2014-11-02 2025-07-09 Nano Precision Medical, Inc. Implantable medical devices for extended release of therapeutic agents
WO2016123027A1 (en) * 2015-01-26 2016-08-04 Nano Precision Medical, Inc. Apparatus and method for promoting fluid uptake into an implant
US20160367677A1 (en) * 2015-06-19 2016-12-22 Board Of Regents, The University Of Texas System Lipid nanodiscs and nanorods as modulators of clotting factor function in vivo
WO2017218354A1 (en) 2016-06-13 2017-12-21 Nano Precision Medical, Inc. Drug delivery device
WO2018067535A1 (en) 2016-10-04 2018-04-12 Nano Precision Medical, Inc. Implant delivery system with hydration promotor capability
KR101946703B1 (ko) * 2017-03-10 2019-04-29 성균관대학교산학협력단 친수성의 나노 필름 구조물을 이용한 무동력 액츄에이터 및 상기 무동력 액츄에이터를 제작하는 방법
EP3760241B1 (en) 2018-03-01 2024-04-17 Titanium Textiles AG Tension-free titanium metal warp knit fabric for surgically shaping soft tissues
MX2020009107A (es) 2018-03-01 2022-10-25 Titanium Textiles Ag Matriz de titanio a base de una tela tejida por urdimbre metálica libre de tensión para la regeneración guiada del tejido.
CN109692695B (zh) * 2018-12-27 2022-02-01 东北大学 一种近红外光响应型纳米二氧化钛复合材料及其制备方法
CN109686594B (zh) * 2019-01-18 2020-11-24 三峡大学 钴基双金属硫化物负极材料的制备方法及其应用
WO2022010846A1 (en) 2020-07-08 2022-01-13 Nano Precision Medical, Inc. Methods to control the rate of release of therapeutic agents from implantable devices
WO2023107950A1 (en) * 2021-12-06 2023-06-15 Case Western Reserve University Implant medical devices
WO2023235302A1 (en) 2022-06-01 2023-12-07 Nano Precision Medical, Inc. Devices, methods and formulations to control release of therapeutic agents from implantable devices
WO2023235298A1 (en) 2022-06-01 2023-12-07 Nano Precision Medical, Inc. Methods and devices to control release of therapeutic agents from implantable devices
CA3255297A1 (en) * 2022-06-03 2023-12-07 Nano Prec Medical Inc DEVICES AND METHODS TO IMPROVE THE BIOAVAILABILITY OF THERAPEUTIC AGENTS
KR20250156699A (ko) 2023-01-06 2025-11-03 나노 프리시전 메디컬, 인코포레이티드 Glp-1 작용제를 위한 제형, 디바이스 및 방법
WO2025147462A1 (en) 2024-01-04 2025-07-10 Nano Precision Medical, Inc. Implantable devices, formulations and methods for body weight management
WO2025147459A1 (en) 2024-01-04 2025-07-10 Nano Precision Medical, Inc. Stabilization of peptides and proteins in implantable devices and formulations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100937167B1 (ko) 2007-06-05 2010-01-15 재단법인서울대학교산학협력재단 나노 포어 어레이를 이용한 나노 구조체의 제조방법
US20100187172A1 (en) * 2007-07-26 2010-07-29 The Penn State Research Foundation Highly-ordered titania nanotube arrays
US20100213046A1 (en) * 2009-01-06 2010-08-26 The Penn State Research Foundation Titania nanotube arrays, methods of manufacture, and photocatalytic conversion of carbon dioxide using same
KR101063761B1 (ko) 2008-11-19 2011-09-08 경원대학교 산학협력단 마개가 형성된 나노튜브를 제조하는 방법 및 이에 의해 제조된 나노튜브

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0883788A (ja) * 1994-09-14 1996-03-26 Oki Electric Ind Co Ltd ドライエッチング方法
ES2205462T3 (es) 1997-03-31 2004-05-01 Alza Corporation Sistema de suministro por dufusion, implantable.
WO2003024357A2 (en) 2001-09-14 2003-03-27 Martin Francis J Microfabricated nanopore device for sustained release of therapeutic agent
US20050118229A1 (en) * 2003-10-21 2005-06-02 Imedd, Inc. Implantable drug delivery device for sustained release of therapeutic agent
CN101191248B (zh) * 2006-12-01 2011-08-10 西南交通大学 在钛基底材料表面制备二氧化钛纳米管阵列层的方法
WO2009114719A2 (en) * 2008-03-13 2009-09-17 Richmond Chemical Corporation Apparatus and method of retaining and releasing molecules from nanostructures by an external stimulus
KR101043584B1 (ko) * 2008-08-20 2011-06-22 한국과학기술원 질소 원자가 선택적으로 도핑된 TiO2-xNx 나노튜브 및 그의 제조방법
EP2405967B1 (en) * 2009-03-12 2020-09-23 Delpor, Inc. Implantable device for long-term delivery of drugs
CN101550581B (zh) 2009-04-03 2011-05-11 西北有色金属研究院 一种双通大面积TiO2纳米管阵列膜的制备方法
US20100269894A1 (en) * 2009-04-28 2010-10-28 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada Titanium dioxide nanotubes and their use in photovoltaic devices
NL2003250C2 (en) * 2009-07-20 2011-01-24 Metal Membranes Com B V Method for producing a membrane and such membrane.
CN101717984A (zh) * 2009-11-05 2010-06-02 兰州大学 一种二氧化钛纳米管薄膜的制备方法
JP2011111660A (ja) * 2009-11-27 2011-06-09 National Institute Of Advanced Industrial Science & Technology チタニアナノチューブアレイ及びその形成方法
CN102220616B (zh) * 2011-05-26 2013-02-27 东南大学 二氧化钛纳米管阵列的制备方法
JP6564187B2 (ja) * 2011-12-05 2019-08-21 ナノ プレシジョン メディカル インコーポレイテッドNano Precision Medical, Inc. チタニアナノチューブ膜を有する、薬物送達用デバイス

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100937167B1 (ko) 2007-06-05 2010-01-15 재단법인서울대학교산학협력재단 나노 포어 어레이를 이용한 나노 구조체의 제조방법
US20100187172A1 (en) * 2007-07-26 2010-07-29 The Penn State Research Foundation Highly-ordered titania nanotube arrays
KR101063761B1 (ko) 2008-11-19 2011-09-08 경원대학교 산학협력단 마개가 형성된 나노튜브를 제조하는 방법 및 이에 의해 제조된 나노튜브
US20100213046A1 (en) * 2009-01-06 2010-08-26 The Penn State Research Foundation Titania nanotube arrays, methods of manufacture, and photocatalytic conversion of carbon dioxide using same

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US9814867B2 (en) 2017-11-14
KR20140106660A (ko) 2014-09-03
US20140371687A1 (en) 2014-12-18
CN103998536A (zh) 2014-08-20
JP2018109236A (ja) 2018-07-12
EP2788439A1 (en) 2014-10-15
WO2013085951A1 (en) 2013-06-13
JP6564187B2 (ja) 2019-08-21
EP2788439A4 (en) 2015-09-02
JP2015500288A (ja) 2015-01-05
CN103998536B (zh) 2017-09-15

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