KR101857090B1 - 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 - Google Patents

무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 Download PDF

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KR101857090B1
KR101857090B1 KR1020127031569A KR20127031569A KR101857090B1 KR 101857090 B1 KR101857090 B1 KR 101857090B1 KR 1020127031569 A KR1020127031569 A KR 1020127031569A KR 20127031569 A KR20127031569 A KR 20127031569A KR 101857090 B1 KR101857090 B1 KR 101857090B1
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atoh1
antisense
oligonucleotide
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oligonucleotides
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KR20130112695A (ko
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조셉 콜라드
올가 크로코바 셔만
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큐알엔에이, 인크.
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KR1020127031569A 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료 Active KR101857090B1 (ko)

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US34865610P 2010-05-26 2010-05-26
US61/348,656 2010-05-26
PCT/US2011/037833 WO2011150005A2 (en) 2010-05-26 2011-05-25 Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1

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KR1020187012859A Division KR20180053419A (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료

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KR101857090B1 true KR101857090B1 (ko) 2018-06-26

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KR1020127031569A Active KR101857090B1 (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료
KR1020187012859A Ceased KR20180053419A (ko) 2010-05-26 2011-05-25 무조(無調)의 동소체 1 (atoh1)에 대한 자연 안티센스 전사체의 저해에 의한 atoh1 관련된 질환의 치료

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EP (2) EP3299464B1 (enExample)
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US11584932B2 (en) 2016-11-01 2023-02-21 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer
US12319913B2 (en) 2018-10-31 2025-06-03 The Research Foundation For The State University Of New York 5-halouracil-modified microRNAs and their use in the treatment of cancer

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US8895528B2 (en) 2010-05-26 2014-11-25 Curna, Inc. Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1
EP2638163B1 (en) 2010-11-12 2017-05-17 The General Hospital Corporation Polycomb-associated non-coding rnas
US9920317B2 (en) 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs
US10174323B2 (en) 2012-05-16 2019-01-08 The General Hospital Corporation Compositions and methods for modulating ATP2A2 expression
AU2013262700A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating hemoglobin gene family expression
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
CA2873779A1 (en) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions and methods for modulating mecp2 expression
JP2015518714A (ja) 2012-05-16 2015-07-06 ラナ セラピューティクス インコーポレイテッド 遺伝子発現を調節するための組成物及び方法
US10058623B2 (en) 2012-05-16 2018-08-28 Translate Bio Ma, Inc. Compositions and methods for modulating UTRN expression
EP2850186B1 (en) 2012-05-16 2018-12-19 Translate Bio MA, Inc. Compositions and methods for modulating smn gene family expression
AU2013312358B2 (en) 2012-09-07 2018-08-09 Massachusetts Eye & Ear Infirmary Treating hearing loss
US20140134136A1 (en) * 2012-11-02 2014-05-15 Massachusetts Eye And Ear Infirmary Compositions and methods for auditory therapy
US9572815B2 (en) 2013-03-15 2017-02-21 St. Jude Children's Research Hospital Methods and compositions of p27KIP1 transcriptional modulators
WO2016022776A2 (en) * 2014-08-06 2016-02-11 Massachusetts Eye And Ear Infirmary Increasing atoh1 life to drive sensorineural hair cell differentiantion
TWI710635B (zh) * 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體
US10858650B2 (en) 2014-10-30 2020-12-08 The General Hospital Corporation Methods for modulating ATRX-dependent gene repression
EP3271460A4 (en) 2015-03-17 2019-03-13 The General Hospital Corporation RNA INTERACTOM OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1)
EP3310783B1 (en) 2015-06-18 2020-11-04 Ting Therapeutics LLC Compositions for the prevention of hearing loss
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