KR101792200B1 - 열감응성 겔 마취제 조성물 - Google Patents
열감응성 겔 마취제 조성물 Download PDFInfo
- Publication number
- KR101792200B1 KR101792200B1 KR1020127028635A KR20127028635A KR101792200B1 KR 101792200 B1 KR101792200 B1 KR 101792200B1 KR 1020127028635 A KR1020127028635 A KR 1020127028635A KR 20127028635 A KR20127028635 A KR 20127028635A KR 101792200 B1 KR101792200 B1 KR 101792200B1
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- castor oil
- poloxamer
- weight
- lidocaine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 33
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- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 3
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Images
Classifications
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Landscapes
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- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/EP2011/055009 WO2011121074A1 (en) | 2010-04-01 | 2011-03-31 | Thermogelling anaesthetic compositions |
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| WO2011121074A1 (en) * | 2010-04-01 | 2011-10-06 | Pharmanest Ab | Thermogelling anaesthetic compositions |
| US10220093B2 (en) | 2013-02-28 | 2019-03-05 | Mira Pharma Corporation | Long-acting semi-solid lipid formulations |
| EP2961380B1 (en) * | 2013-02-28 | 2020-04-08 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid formulations and its compositions |
| GB201305622D0 (en) * | 2013-03-27 | 2013-05-15 | Sas Ltd | Composition |
| CA2961660A1 (en) * | 2014-10-01 | 2016-04-07 | Als Mountain Llc | Pharmaceutical composition comprising aspirin, metformin, and serotonin with non-ionic surfactant |
| JP6678946B2 (ja) | 2015-03-25 | 2020-04-15 | テルモ株式会社 | ゲル状局所麻酔剤およびそれを用いたゲル状局所麻酔製剤 |
| EP3375456B1 (en) | 2015-11-12 | 2023-05-03 | Terumo Kabushiki Kaisha | Sustained-release topically administered agent |
| CN105769839B (zh) * | 2016-05-17 | 2019-06-11 | 山西远扬医药科技有限公司 | 一种复方利多卡因药物组合物及其制备方法 |
| CN107149697B (zh) * | 2017-03-24 | 2020-07-31 | 王科 | 一种皮肤表面麻醉敷料、其制备方法及使用方法 |
| US10561606B2 (en) | 2017-12-06 | 2020-02-18 | Mira Pharma Corporation | Injectable long-acting local anesthetic semi-solid gel formulations |
| US11426418B2 (en) | 2017-12-06 | 2022-08-30 | Mira Pharma Corporation | Injectable long-acting semi-solid gel formulations |
| CN108309928A (zh) * | 2018-03-22 | 2018-07-24 | 兆科（广州）眼科药物有限公司 | 一种妇科术后止痛药物组合物及其制备方法 |
| IT201800004036A1 (it) * | 2018-03-28 | 2019-09-28 | Teres Srl | Gel transdermico |
| WO2019217536A1 (en) * | 2018-05-08 | 2019-11-14 | University Of Connecticut | Long-acting local anesthetic formulation |
| CN111840553A (zh) * | 2019-04-15 | 2020-10-30 | 湖州依诺唯新药物制剂有限公司 | 脂性药物制剂及其应用 |
| JP7646175B2 (ja) * | 2019-11-28 | 2025-03-17 | 東洋製薬化成株式会社 | リドカイン含有外用医薬組成物 |
| EP4110293A4 (en) * | 2020-02-25 | 2024-07-10 | The University of North Carolina at Chapel Hill | EUTECTIC-BASED ANESTHESIC COMPOSITIONS AND CORRESPONDING APPLICATIONS |
| WO2022055927A1 (en) * | 2020-09-11 | 2022-03-17 | Ps Therapy Ltd. | Topical compositions and methods of use |
| WO2023150345A1 (en) * | 2022-02-04 | 2023-08-10 | Intact Therapeutics, Inc. | Mesalamine pharmaceutical formulations and methods of use thereof |
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| IT1248014B (it) * | 1991-06-07 | 1995-01-05 | Inverni Della Beffa Spa | Preparazioni oftalmiche a rilascio protratto |
| SE9601421D0 (sv) | 1996-04-12 | 1996-04-12 | Astra Ab | New composition |
| US6217900B1 (en) * | 1997-04-30 | 2001-04-17 | American Home Products Corporation | Vesicular complexes and methods of making and using the same |
| JP3782551B2 (ja) * | 1997-06-24 | 2006-06-07 | 鉄郎 高山 | 鎮痛組成物 |
| US6528086B2 (en) | 1999-09-28 | 2003-03-04 | Zars, Inc. | Methods and apparatus for drug delivery involving phase changing formulations |
| KR100416646B1 (ko) | 2000-08-14 | 2004-02-05 | 구주제약주식회사 | 리도카인을 함유한 조루치료용 마이크로에멀젼 하이드로겔 제형의 약학 조성물 |
| GB0120701D0 (en) | 2001-08-24 | 2001-10-17 | Maelor Pharmaceuticals Ltd | Pharmaceutical formulations |
| GB0120702D0 (en) | 2001-08-24 | 2001-10-17 | Maelor Pharmaceuticals Ltd | Anaesthetic formulations |
| BR0313060A (pt) * | 2002-07-29 | 2005-06-28 | Transform Pharmaceuticals Inc | Composições farmacêuticas aquosas de 2,6-diisopropilfenol |
| US20040220283A1 (en) * | 2002-07-29 | 2004-11-04 | Transform Pharmaceuticals, Inc. | Aqueous 2,6-diisopropylphenol pharmaceutical compositions |
| AU2003900887A0 (en) | 2003-02-27 | 2003-03-13 | Novasel Australia Pty Ltd | Poloxamer emulsion preparations |
| ES2237298B1 (es) * | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
| US20050084508A1 (en) | 2003-07-22 | 2005-04-21 | Vancaillie Thierry G. | Topical anesthesia formulation for bodily cavities |
| US20080154210A1 (en) | 2004-05-28 | 2008-06-26 | Oryxe | Mixture for Transdermal Delivery of Low and High Molecular Weight Compounds |
| US20070190124A1 (en) | 2004-06-07 | 2007-08-16 | Jie Zhang | Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs |
| AU2006201233B2 (en) | 2006-03-24 | 2010-10-07 | Alan Hewitt | Topical anesthesia formulation for bodily cavities |
| US20070298005A1 (en) | 2006-06-22 | 2007-12-27 | Marie-Josee Thibault | Injectable composition for treatment of skin defects or deformations |
| CA2659344C (en) | 2006-07-31 | 2015-03-17 | Laboratoires Besins International | Treatment and prevention of excessive scarring |
| JP5301205B2 (ja) * | 2008-05-28 | 2013-09-25 | 東興薬品工業株式会社 | ゲル軟膏組成物 |
| WO2011121074A1 (en) * | 2010-04-01 | 2011-10-06 | Pharmanest Ab | Thermogelling anaesthetic compositions |
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