KR101752789B1 - 연속 세포 배양에서 목적 폴리펩티드 또는 바이러스를 생산하는 방법 - Google Patents
연속 세포 배양에서 목적 폴리펩티드 또는 바이러스를 생산하는 방법 Download PDFInfo
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- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24087—ADAMTS13 endopeptidase (3.4.24.87)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
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| US61/230,313 | 2009-07-31 | ||
| PCT/EP2010/061191 WO2011012725A1 (en) | 2009-07-31 | 2010-08-02 | Method of producing a polypeptide or virus of interest in a continuous cell culture |
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| KR1020127004996A Active KR101752789B1 (ko) | 2009-07-31 | 2010-08-02 | 연속 세포 배양에서 목적 폴리펩티드 또는 바이러스를 생산하는 방법 |
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| CN103097522A (zh) * | 2010-07-08 | 2013-05-08 | 巴克斯特国际公司 | 在细胞培养物中生产重组adamts13的方法 |
| JP5995871B2 (ja) * | 2011-01-17 | 2016-09-21 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 分離装置およびその使用 |
| AU2012257736B2 (en) | 2011-05-13 | 2015-12-10 | Octapharma Ag | A method of increasing the productivity of eucaryotic cells in the production of recombinant FVIII |
| JP5897708B2 (ja) | 2011-07-01 | 2016-03-30 | アムジエン・インコーポレーテツド | 哺乳類細胞培養物 |
| CN203129697U (zh) | 2013-02-05 | 2013-08-14 | 客贝利(厦门)休闲用品有限公司 | 一种帐篷架杆 |
| HRP20180424T1 (hr) | 2011-11-24 | 2018-06-29 | Genethon | Skalabilni sustav proizvodnje lentivirusnih vektora, kompatibilan s industrijskim farmaceutskim primjenama |
| US9574167B2 (en) | 2013-02-15 | 2017-02-21 | Pharyx, Inc. | Methods and apparatus for independent control of product and reactant concentrations |
| RU2768003C2 (ru) | 2013-03-08 | 2022-03-22 | Джензим Корпорейшн | Интегрированное непрерывное производство терапевтических белковых лекарственных веществ |
| US9217168B2 (en) | 2013-03-14 | 2015-12-22 | Momenta Pharmaceuticals, Inc. | Methods of cell culture |
| US10316282B2 (en) | 2013-03-19 | 2019-06-11 | Cmc Biologics A/S | Method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process |
| US10392603B2 (en) * | 2013-08-30 | 2019-08-27 | The Chemo-Sero-Therapeutic Research Institute | Method of viral purification |
| US11390663B2 (en) | 2013-10-11 | 2022-07-19 | Regeneron Pharmaceuticals, Inc. | Metabolically optimized cell culture |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI709570B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析法及製法 |
| AU2015240353A1 (en) | 2014-04-01 | 2016-11-17 | Advantech Bioscience Farmaceutica Ltda. | Stable Factor VIII formulations with low sugar-glycine |
| AU2015240354A1 (en) | 2014-04-01 | 2016-11-17 | Advantech Bioscience Farmaceutica Ltda. | Stabilization of Factor VIII without calcium as an excipient |
| US10829539B2 (en) * | 2014-06-13 | 2020-11-10 | Csl Limited | Production of recombinant von Willebrand factor in a bioreactor |
| CN116083344A (zh) * | 2016-01-26 | 2023-05-09 | 勃林格殷格翰国际公司 | 对连续流动搅拌釜反应器细胞培养系统的连接灌注 |
| EP3443064A1 (en) | 2016-04-15 | 2019-02-20 | Boehringer Ingelheim International GmbH | Cell retention device and method |
| ES2848701T3 (es) * | 2016-12-21 | 2021-08-11 | Hoffmann La Roche | Control de la proliferación de células eucariotas |
| IL321253A (en) | 2018-05-01 | 2025-08-01 | Amgen Inc | Antibodies with a modulated glycan profile |
| WO2019239780A1 (ja) * | 2018-06-15 | 2019-12-19 | 富士フイルム株式会社 | 細胞培養方法、細胞培養装置、及び生産物の製造方法 |
| HK40046210A (en) | 2018-08-31 | 2021-10-29 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
| CN113355297A (zh) * | 2021-06-23 | 2021-09-07 | 吉林冠界生物技术有限公司 | 一种灌流式培养全悬浮mdck细胞生产重组禽流感病毒的方法 |
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| US5019512A (en) | 1989-03-17 | 1991-05-28 | Baxter International Inc. | Spin filter for removing substantially cell-free culture medium from suspension cell culture system |
| US5626734A (en) | 1995-08-18 | 1997-05-06 | University Technologies International, Inc. | Filter for perfusion cultures of animal cells and the like |
| IL154879A0 (en) | 2000-10-02 | 2003-10-31 | Novo Nordisk As | Factor vii glycoforms |
| NZ533084A (en) * | 2001-11-28 | 2006-02-24 | Sandoz Ag | Cell culture process |
| TWI384069B (zh) | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
| CA2606351C (en) | 2005-06-17 | 2016-12-13 | Baxter International Inc. | Adamts13-comprising compositions having thrombolytic activity |
| KR101423344B1 (ko) * | 2006-01-04 | 2014-07-30 | 백스터 인터내셔널 인코포레이티드 | 올리고펩티드-무함유 세포 배양 배지를 이용하여 단백질을 발현시키는 방법 |
| SI2235197T1 (sl) * | 2007-12-27 | 2017-10-30 | Baxalta GmbH | Procesi celične kulture |
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