KR101744895B1 - 미라미스틴을 포함하는 약학적 제제 - Google Patents
미라미스틴을 포함하는 약학적 제제 Download PDFInfo
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- KR101744895B1 KR101744895B1 KR1020127024396A KR20127024396A KR101744895B1 KR 101744895 B1 KR101744895 B1 KR 101744895B1 KR 1020127024396 A KR1020127024396 A KR 1020127024396A KR 20127024396 A KR20127024396 A KR 20127024396A KR 101744895 B1 KR101744895 B1 KR 101744895B1
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- Prior art keywords
- propyl
- myristoylamino
- pharmaceutical
- dimethyl
- delete delete
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- JQQZCIIDNVIQKO-UHFFFAOYSA-N benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC1=CC=CC=C1 JQQZCIIDNVIQKO-UHFFFAOYSA-N 0.000 title claims abstract description 8
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 16
- -1 dimethyl- (3- [myristoylamino] propyl) amine Chemical class 0.000 claims abstract description 13
- IFYDWYVPVAMGRO-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]tetradecanamide Chemical compound CCCCCCCCCCCCCC(=O)NCCCN(C)C IFYDWYVPVAMGRO-UHFFFAOYSA-N 0.000 claims abstract description 10
- 150000004682 monohydrates Chemical class 0.000 claims abstract description 8
- 239000008063 pharmaceutical solvent Substances 0.000 claims abstract description 8
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 239000008194 pharmaceutical composition Substances 0.000 claims description 11
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 5
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- HUCJFAOMUPXHDK-UHFFFAOYSA-N Xylometazoline Chemical compound CC1=CC(C(C)(C)C)=CC(C)=C1CC1=NCCN1 HUCJFAOMUPXHDK-UHFFFAOYSA-N 0.000 claims description 4
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims description 4
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- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 claims description 2
- VEPZOLKTNZOTTQ-UHFFFAOYSA-N 1-butyl-n-(2,4,6-trimethylphenyl)pyrrolidine-2-carboxamide Chemical compound CCCCN1CCCC1C(=O)NC1=C(C)C=C(C)C=C1C VEPZOLKTNZOTTQ-UHFFFAOYSA-N 0.000 claims description 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims description 2
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- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims description 2
- GOZBHBFUQHMKQB-UHFFFAOYSA-N trimecaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=C(C)C=C1C GOZBHBFUQHMKQB-UHFFFAOYSA-N 0.000 claims description 2
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- VQGHOUODWALEFC-UHFFFAOYSA-N 2-phenylpyridine Chemical compound C1=CC=CC=C1C1=CC=CC=N1 VQGHOUODWALEFC-UHFFFAOYSA-N 0.000 claims 2
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- DLNKOYKMWOXYQA-APPZFPTMSA-N phenylpropanolamine Chemical compound C[C@@H](N)[C@H](O)C1=CC=CC=C1 DLNKOYKMWOXYQA-APPZFPTMSA-N 0.000 claims 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Otolaryngology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2010/001056 | 2010-02-19 | ||
| PCT/EP2010/001056 WO2011100994A1 (de) | 2010-02-19 | 2010-02-19 | Arzneimittel enthaltend myramistin |
| PCT/EP2011/000691 WO2011101113A1 (de) | 2010-02-19 | 2011-02-15 | Arzneimittel enthaltend myramistin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20130018242A KR20130018242A (ko) | 2013-02-20 |
| KR101744895B1 true KR101744895B1 (ko) | 2017-06-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020127024396A Active KR101744895B1 (ko) | 2010-02-19 | 2011-02-15 | 미라미스틴을 포함하는 약학적 제제 |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP2536400B1 (enExample) |
| JP (1) | JP5746224B2 (enExample) |
| KR (1) | KR101744895B1 (enExample) |
| CN (1) | CN102869354B (enExample) |
| AU (1) | AU2011217530B2 (enExample) |
| BR (1) | BR112012020828B1 (enExample) |
| CY (1) | CY1115833T1 (enExample) |
| DK (1) | DK2536400T3 (enExample) |
| EA (1) | EA022283B1 (enExample) |
| ES (1) | ES2524379T3 (enExample) |
| GE (1) | GEP20135942B (enExample) |
| HR (1) | HRP20141173T1 (enExample) |
| IL (1) | IL221501A (enExample) |
| MD (1) | MD4411C1 (enExample) |
| MX (1) | MX2012009646A (enExample) |
| PL (1) | PL2536400T3 (enExample) |
| PT (1) | PT2536400E (enExample) |
| SI (1) | SI2536400T1 (enExample) |
| UA (1) | UA103968C2 (enExample) |
| WO (2) | WO2011100994A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014175757A1 (ru) * | 2013-04-22 | 2014-10-30 | Общество с ограниченной ответственностью "Нанобиотех" | Антисептический ветеринарный препарат и способы его использования |
| RU2542376C1 (ru) * | 2013-07-30 | 2015-02-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Средство для лечения гнойно-воспалительных процессов мягких тканей и слизистых оболочек |
| CN109456218A (zh) * | 2018-12-17 | 2019-03-12 | 山东诚汇双达药业有限公司 | 一种盐酸三甲卡因的生产方法 |
| GB202003240D0 (en) * | 2020-03-05 | 2020-04-22 | Ecosynth Nv | Antiviral treatment |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993000892A1 (fr) | 1991-07-10 | 1993-01-21 | Jury Semenovich Krivoshein | Preparation pharmaceutique |
| US20040033208A1 (en) * | 2000-12-20 | 2004-02-19 | Cagle Gerald D. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| WO2006075932A2 (en) * | 2005-01-13 | 2006-07-20 | Otkrytoe Akzionernoe Obschestvo 'sistema Venture' | Remedy to accelerate healing of wound and burn |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2459062A (en) | 1944-02-08 | 1949-01-11 | American Cyanamid Co | Quaternary ammonium compounds |
| US4093711A (en) * | 1976-08-13 | 1978-06-06 | Noxell Corporation | Oral hygiene |
| SU1796185A1 (ru) | 1990-06-23 | 1993-02-23 | Adolina P Rudko | Фунгицид 2 |
| US5393491A (en) | 1993-09-22 | 1995-02-28 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| UA30143C2 (uk) * | 1997-12-30 | 2001-11-15 | Юрій Семенович Кривошеін | Лікувальний препарат для профілактики та лікування інфекційних та запальних захворювань |
| RU2157214C2 (ru) | 1998-04-16 | 2000-10-10 | Государственный научный центр лекарственных средств | Противовоспалительное и антимикробное лекарственное средство для местного применения |
| RU2161961C1 (ru) * | 2000-03-17 | 2001-01-20 | Кривошеин Юрий Семенович | Лекарственный препарат |
| RU2177314C2 (ru) | 2000-03-22 | 2001-12-27 | Кривошеин Юрий Семенович | Состав с антисептическими, репаративными и болеутоляющими свойствами |
| RU2173142C1 (ru) | 2000-04-18 | 2001-09-10 | Кривошеин Юрий Семенович | Вагинальный контрацептив |
| RU2164135C1 (ru) | 2000-04-27 | 2001-03-20 | Рудько Адолина Петровна | Глазной антисептик |
| RU2184534C2 (ru) | 2000-04-27 | 2002-07-10 | Рудько Адолина Петровна | Антисептические таблетки |
| RU2185157C2 (ru) | 2000-06-26 | 2002-07-20 | Рудько Адолина Петровна | Средство для лечения ожоговых ран |
| RU2185156C2 (ru) | 2000-06-26 | 2002-07-20 | Рудько Адолина Петровна | Интраназальный антисептик |
| RU2188005C2 (ru) | 2000-10-04 | 2002-08-27 | Рудько Адолина Петровна | Состав для антисептической обработки кожи рук и операционного поля |
| WO2002049627A2 (en) * | 2000-12-20 | 2002-06-27 | Alcon, Inc. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| WO2002049633A2 (en) | 2000-12-20 | 2002-06-27 | Alcon, Inc. | Use of amidoamines to treat or prevent acanthamoeba and fungal infections |
| RU2234313C1 (ru) * | 2003-06-04 | 2004-08-20 | Кривошеин Юрий Семенович | Средство инактивации коронавирусов |
| US20070264226A1 (en) | 2006-05-10 | 2007-11-15 | Karagoezian Hampar L | Synergistically enhanced disinfecting solutions |
| CN101562971A (zh) * | 2006-05-10 | 2009-10-21 | S.K.药物公司 | 协同增强的消毒溶液 |
| CN101100432B (zh) * | 2006-07-04 | 2010-08-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 苯甲基二甲基[3-(肉豆蔻酰胺基)丙基]氯化铵的合成方法 |
| DE102008039234A1 (de) * | 2007-10-29 | 2009-05-07 | Neudecker & Jolitz Gmbh & Co. | Motorisch betriebener Türöffner und Motor für einen Türöffner |
| UA30143U (en) | 2007-11-14 | 2008-02-11 | Валерий Михайлович Шарапов | Piezoelectric transformer |
| DE102008039254A1 (de) * | 2008-08-20 | 2010-02-25 | Megainpharm Gmbh | Arzneimittel |
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2010
- 2010-02-19 WO PCT/EP2010/001056 patent/WO2011100994A1/de not_active Ceased
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2011
- 2011-02-15 AU AU2011217530A patent/AU2011217530B2/en active Active
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- 2011-02-15 DK DK11708184.4T patent/DK2536400T3/en active
- 2011-02-15 EP EP11708184.4A patent/EP2536400B1/de active Active
- 2011-02-15 HR HRP20141173AT patent/HRP20141173T1/hr unknown
- 2011-02-15 CN CN201180014472.7A patent/CN102869354B/zh active Active
- 2011-02-15 SI SI201130337T patent/SI2536400T1/sl unknown
- 2011-02-15 GE GEAP201112831A patent/GEP20135942B/en unknown
- 2011-02-15 BR BR112012020828-4A patent/BR112012020828B1/pt not_active IP Right Cessation
- 2011-02-15 PT PT117081844T patent/PT2536400E/pt unknown
- 2011-02-15 WO PCT/EP2011/000691 patent/WO2011101113A1/de not_active Ceased
- 2011-02-15 KR KR1020127024396A patent/KR101744895B1/ko active Active
- 2011-02-15 EA EA201201158A patent/EA022283B1/ru unknown
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2012
- 2012-08-16 IL IL221501A patent/IL221501A/en active IP Right Grant
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2014
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993000892A1 (fr) | 1991-07-10 | 1993-01-21 | Jury Semenovich Krivoshein | Preparation pharmaceutique |
| US20040033208A1 (en) * | 2000-12-20 | 2004-02-19 | Cagle Gerald D. | Antifungal compositions containing an antibiotic and one or more amidoamines |
| WO2006075932A2 (en) * | 2005-01-13 | 2006-07-20 | Otkrytoe Akzionernoe Obschestvo 'sistema Venture' | Remedy to accelerate healing of wound and burn |
Also Published As
| Publication number | Publication date |
|---|---|
| MD4411C1 (ro) | 2016-11-30 |
| BR112012020828B1 (pt) | 2021-01-12 |
| PT2536400E (pt) | 2014-11-27 |
| KR20130018242A (ko) | 2013-02-20 |
| BR112012020828A2 (pt) | 2016-06-28 |
| PL2536400T3 (pl) | 2015-04-30 |
| JP5746224B2 (ja) | 2015-07-08 |
| SI2536400T1 (sl) | 2015-01-30 |
| CN102869354B (zh) | 2015-12-16 |
| EA201201158A1 (ru) | 2013-02-28 |
| AU2011217530A1 (en) | 2012-09-13 |
| GEP20135942B (en) | 2013-10-10 |
| CN102869354A (zh) | 2013-01-09 |
| UA103968C2 (ru) | 2013-12-10 |
| WO2011100994A1 (de) | 2011-08-25 |
| AU2011217530B2 (en) | 2014-01-16 |
| HK1179164A1 (zh) | 2013-09-27 |
| WO2011101113A1 (de) | 2011-08-25 |
| EA022283B1 (ru) | 2015-12-30 |
| MX2012009646A (es) | 2013-02-11 |
| IL221501A (en) | 2016-11-30 |
| DK2536400T3 (en) | 2014-12-15 |
| CY1115833T1 (el) | 2017-01-25 |
| HRP20141173T1 (hr) | 2015-01-30 |
| EP2536400B1 (de) | 2014-09-24 |
| EP2536400A1 (de) | 2012-12-26 |
| ES2524379T3 (es) | 2014-12-05 |
| MD20120079A2 (en) | 2013-01-31 |
| MD4411B1 (ro) | 2016-04-30 |
| JP2013519695A (ja) | 2013-05-30 |
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